302 completed, 106 unknown, 50 recruiting, 31 terminated. 223 Not applicable, 37 Phase 2, 30 Phase 3, 29 Phase 4, 12 Phase 1.
Follow Trauma: new trials by email Literature Review of Trauma trials Research Report on Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon Cameroon-Adapted SBIRT, Usual Care - Alcohol Use Disorder, Alcohol-Related Injury | Not applicable | Not yet recruiting | University of Buea | 690 | 2027-03-01 | 2026-06-30 |
| Prospective Study of Induction Medications Used in the Trauma RSI Ketamine, Etomidate, Propofol - Trauma, Rapid Sequence Intubation | Withdrawn | University of Southern California | 2027-01-01 | 2026-05-04 | ||
| Impact of Mobile Health Technology Application on Proximal Humerus Fracture Care Practice Step wise post-procedure mobile health shared rehabilitation teaching video instructions modules (as per fracture type) - Proximal Humerus Fracture, Trauma | Not applicable | Not yet recruiting | Aga Khan University Hospital, Pakistan | 60 | 2026-12-01 | 2025-10-01 |
| Hospital Based Continuous Patient Monitoring System Consumer Wearable Device Vital Sign Measurement - Trauma, Appendectomy | Not applicable | Recruiting | University of Alabama at Birmingham | 250 | 2026-10-19 | 2026-10-27 |
| Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness ITR Healing intervention - Stress, Trauma | Not applicable | Not yet recruiting | University of Michigan | 90 | 2026-10-05 | 2026-10-02 |
| Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual - Trauma Exposure, Trauma | Not applicable | Recruiting | Anthony Vesco | 400 | 2026-10-01 | 2026-09-15 |
| Inferior Vena Cava Versus Subclavian Vein Collapsibility for Predicting Fluid Responsiveness in Trauma Hemorrhagic Shock Hemorrhagic Shock, Trauma | Not yet recruiting | Assiut University | 120 | 2026-10-01 | 2026-09-14 | |
| Data-Driven Lay First Responder Program in Cameroon Lay First Responder (LFR) training - Trauma, Injury | Not applicable | Not yet recruiting | Sabrinah Christie | 1812 | 2026-09-01 | 2026-05-12 |
| Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT) Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT), Treatment as Usual (TAU) - Trauma, Posttraumatic Stress Disorder | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 30 | 2026-09-01 | 2026-02-09 |
| TBE Zone 0/1 PMS in Japan Gore® TAG® Thoracic Aortic Branch Stent Graft System - Aneurysm of Aorta, Thoracic, Dissection of Aorta, Thoracic | Not yet recruiting | W.L.Gore & Associates | 75 | 2026-09-01 | 2026-07-09 | |
| Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen - Trauma, Rib Fractures | Not applicable | Not yet recruiting | Loma Linda University | 30 | 2026-09-01 | 2026-02-09 |
| Litter Packaging in the Lateral Position: Effects of Position and Vacuum Mattress Packaging on Pulmonary Function Patient packaging in a rescue litter - Trauma | Not applicable | Not yet recruiting | University of California, San Francisco | 24 | 2026-08-15 | 2026-06-12 |
| Comparing NISS and ISS for Mortality Prediction in Trauma Patients Trauma | Completed | Al-Nahrain University | 458 | 2026-06-10 | 2026-09-10 | |
| Clinical Evaluation of an AI Risk Prediction System (AI-TRiPS) AI-TRiPS Device - Trauma, Injury | Early Phase 1 | Not yet recruiting | Queen Mary University of London | 1200 | 2026-06-01 | 2026-06-08 |
| Trauma-Informed Yoga Intervention in Young Women Trauma-Informed Yoga Intervention Program - Trauma, Young Adult Females | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 46 | 2026-06-01 | 2026-05-15 |
| Prenatal Yoga Intervention in Pregnant Women Prenatal Yoga - Pregnant Women, Prenatal Yoga | Not applicable | Recruiting | Saglik Bilimleri Universitesi | 46 | 2026-05-15 | 2026-05-14 |
| Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion Number of Participants with massive blood transfusion - Thromboembolus, Massive Blood Transfusion; Thrombocytopenia | Completed | Zeliha Alicikus | 75 | 2026-04-30 | 2026-10-08 | |
| Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot) Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT) - Trauma, Posttraumatic Stress Disorder | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 7 | 2026-04-01 | 2026-02-09 |
| Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD) Emotion Regulation, Exposure, Cognitive Processing - PTSD, Trauma | Not applicable | Recruiting | University of Rochester | 200 | 2026-03-15 | 2026-04-08 |
| Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery Nutrition Supplements - Fresubin KCAL Drinks - Trauma, Critical Illness | Not applicable | Recruiting | Duke University | 60 | 2026-02-18 | 2026-06-03 |
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Wounds and Injuries (552) · Stress Disorders, Post-Traumatic (45) · Hemorrhage (32) · Anxiety Disorders (29) · Sepsis (29) · Critical Illness (25) · Depression (23) · Emergencies (19) · Hemostatic Disorders (19) · Fractures, Bone (18) · Shock (18) · Burns (16) · Multiple Trauma (16) · Pain (15) · Shock, Hemorrhagic (15)
Pathological Conditions, Signs and Symptoms (189) · Pathologic Processes (139) · Mental Disorders (85) · Signs and Symptoms (65) · Cardiovascular Diseases (64) · Vascular Diseases (57) · Nervous System Diseases (54) · Disease Attributes (51) · Trauma and Stressor Related Disorders (49) · Infections (46) · Stress Disorders, Traumatic (46) · Neurologic Manifestations (44) · Behavior (42) · Respiratory Tract Diseases (37) · Hemic and Lymphatic Diseases (34)
Fibrinogen (7) · Saline Solution (7) · Standard of Care (7) · Ibuprofen (5) · Ketamine (5) · Sodium Chloride (5) · Therapeutics (5) · Blood Specimen Collection (4) · Etomidate (4) · Magnetic Resonance Spectroscopy (4) · Midazolam (4) · Tramadol (4) · Acetaminophen (3) · Analgesics, Opioid (3) · Anti-Inflammatory Agents, Non-Steroidal (3)
Karolinska Institutet (9) · Harvard University (8) · Copenhagen University Hospital, Rigshospitalet (7) · Massachusetts General Hospital (7) · Methodist Health System (7) · Assiut University (6) · Novo Nordisk A/S (6) · Ajou University School of Medicine (5) · Al-Nahrain University (5) · Denver Health and Hospital Authority (5) · HemoSonics LLC (5) · International Institute of Rescue Research and Education (5) · NYU Langone Health (5) · Teesside University (5) · Unity Health Toronto (5)
United States (205) · Canada (44) · France (25) · United Kingdom (24) · Germany (19) · Switzerland (18) · Turkey (Türkiye) (16) · Netherlands (15) · Italy (13) · Denmark (12) · South Korea (11) · Sweden (11) · Australia (10) · China (10) · Norway (10)
Andrew Karpisek, MD (3) · In Kyong Yi, MD (3) · John R Weisz, PhD (3) · Lukasz Szarpak (3) · R. Nicholas Carleton, PhD (3) · Salvador Navarro-Soto, MD, PhD (3) · Andrea Campos-Serra, MD (2) · Audis Bethea, PharmD, BCPS (2) · Ayman El-Menyar, MD (2) · Catherine M Kuza, MD (2) · Conner McDaniel, MD (2) · Diansan Su, MD,PHD (2) · Eva-Corina Caragounis, MD (2)
PMID 18375483, PMID 18580208, PMID 20802500, PMID 22110166, PMID 23401516, PMID 24137663, PMID 25647203, PMID 39565635, PMID 10319217, PMID 10376632, PMID 10434409, PMID 10487591, PMID 10623981, PMID 10707230, PMID 10781452, PMID 10856313, PMID 11529214, PMID 11594901, PMID 11604980, PMID 11804251, PMID 11881887, PMID 11982463, PMID 12084639, PMID 12131409, PMID 12169936, PMID 12448594, PMID 12563237, PMID 12576361, PMID 12727572, PMID 12755163, PMID 12777902, PMID 12904861, PMID 12941232, PMID 15037369, PMID 15157244, PMID 15162112, PMID 15242867, PMID 15269195, PMID 15286537, PMID 15319720, PMID 15576519, PMID 15643733, PMID 15734783, PMID 15761334, PMID 15840076, PMID 15851777, PMID 15920409, PMID 15983575, PMID 16009794, PMID 16096533
2014 (2), 2018 (2), U54GM062119 (2), 1UL1TR003098 (1), 2004 (1), 2005 (1), 2019 (1), DP2LM012339 (1), K01MH115794 (1), K01TW012689 (1), M01RR002558 (1), P01HL131478 (1), P50GM053789 (1), R01AA027512 (1), R01DA021887 (1)