69 completed, 29 unknown, 15 recruiting, 7 terminated. 27 Not applicable, 12 Phase 3, 11 Phase 2, 5 Phase 1, 3 Phase 4.
Follow Multiple Trauma: new trials by email Literature Review of Multiple Trauma trials Research Report on Multiple Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Development and Internal Validation of a Multimodal Prediction Score for Early Hemodynamic Deterioration in Adult Polytrauma Patients Multiple Trauma, Polytrauma | Not yet recruiting | Assiut University | 300 | 2026-10-01 | 2026-09-30 | |
| Predictors of In-Hospital Mortality in Severe Abdominal Trauma Abdominal Injuries, Wounds and Injuries | Recruiting | Minia University | 430 | 2026-10-01 | 2026-10-02 | |
| Affordable, Tailored Therapy for Financially Vulnerable People With Trauma-related Injuries Trauma (Including Fractures), Multiple Trauma/Injuries | Not yet recruiting | Radboud University Medical Center | 17 | 2026-10-01 | 2026-09-15 | |
| BLOCK-TRAUMA Study Polytrauma, Regional Anaesthesia | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 500 | 2026-10-01 | 2026-10-02 | |
| Polytrauma Patients and Non-technical Skills Questions - Polytrauma, Polytrauma Patients | Completed | Antalya Training and Research Hospital | 16 | 2026-04-21 | 2026-05-27 | |
| Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial Veno-arterial Carbondioxide gap, Conventional resuscitation end points - Polytrauma, Resuscitation, Trauma Patients | Phase 4 | Recruiting | Pakistan Institute of Medical Sciences | 60 | 2026-03-16 | 2026-03-18 |
| Prognostic Value of Capillary Lactatemia in Potentially Severe Polytrauma Patients capillary blood sampling - Polytrauma | Not applicable | Recruiting | Centre Hospitalier Universitaire de Nice | 550 | 2026-02-07 | 2026-03-30 |
| Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage in the Prehospital and Emergency Room Setting Exanguination, Polytrauma | Not yet recruiting | Medical University of Graz | 50 | 2026-02-01 | 2025-12-10 | |
| Mortality Prediction Using Trauma Scores Trauma, Multiple | Recruiting | Al-Nahrain University | 150 | 2025-11-28 | 2026-09-17 | |
| Early Norepinephrine in Trauma Patients With Hemorrhagic Shock Norepinephrine, Placebo - Trauma, Multiple | Phase 1 / Phase 2 | Enrolling by invitation | Visarat Palitnonkiat | 40 | 2025-05-20 | 2025-05-18 |
| Evaluation of Patients Suffering From Polytrauma Admitted to the ICU Polytrauma Patients | Active not recruiting | Jessa Hospital | 417 | 2025-04-10 | 2026-03-19 | |
| Comparison of RTS and MGAP Scores in Predicting Outcomes of Trauma Patients Multiple Trauma/Injuries | Recruiting | Al-Nahrain University | 200 | 2025-01-20 | 2026-03-04 | |
| TRISS as a Predictor of Trauma Patient Outcomes Trauma, Multiple | Completed | Al-Nahrain University | 204 | 2024-11-15 | 2026-03-06 | |
| Comparing Exponential Injury Severity Score (EISS) With Injury Severity Score (ISS) and New Injury Severity Score (NISS) Polytrauma | Recruiting | Assiut University | 250 | 2024-11-01 | 2024-12-06 | |
| Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage Exanguination, NCTH | Recruiting | Medical University of Graz | 10 | 2024-11-01 | 2025-04-17 | |
| Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation Stroke, Acquired Brain Injury | Active not recruiting | Tan Tock Seng Hospital | 10000 | 2024-06-01 | 2026-10-07 | |
| Role of Active Deresuscitation After Resuscitation: Furosemide Injection, Metolazone Tablets - Fluid Overload, Critical Illness | Phase 2 | Unknown | Unity Health Toronto | 120 | 2024-05-01 | 2024-03-22 |
| Incidence and Associated Risk Factors of ARC in the Trauma Critically Ill Older Than 50 Years Old No intervention - Augmented Renal Clearance, Critical Illness | Withdrawn | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2024-03-01 | 2024-12-13 | ||
| From Great Surgeons to Brilliant Observators, Evolution of Penetrating Neck Trauma in a Single Center Reference in Spain Penetrating Neck Trauma | Unknown | Hospital del Mar | 1000 | 2024-02-20 | 2024-01-29 | |
| AI Assisted Detection of Fractures on X-Rays (FRACT-AI) Cases reading, Ground truthing - Fracture, Bone Fracture | Completed | Oxford University Hospitals NHS Trust | 21 | 2024-02-08 | 2025-11-24 |
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Wounds and Injuries (46) · Brain Injuries, Traumatic (11) · Critical Illness (9) · Sepsis (9) · Accidental Injuries (8) · Hemorrhage (8) · Shock (8) · Shock, Hemorrhagic (7) · Wounds, Nonpenetrating (7) · Acute Pain (6) · Inflammation (6) · Burns (5) · Emergencies (5) · Fractures, Bone (5)
Wounds and Injuries (91) · Pathological Conditions, Signs and Symptoms (47) · Pathologic Processes (33) · Nervous System Diseases (22) · Signs and Symptoms (17) · Central Nervous System Diseases (16) · Trauma, Nervous System (16) · Disease Attributes (14) · Neurologic Manifestations (14) · Brain Diseases (13) · Cardiovascular Diseases (11) · Craniocerebral Trauma (10) · Shock (10) · Vascular Diseases (10) · Infections (9)
Saline Solution (4) · Control Groups (3) · Epoetin Alfa (2) · Injury Severity Score (2) · Ketamine (2) · Acetaminophen (1) · Analgesics (1) · Ascorbic Acid (1) · Blood Specimen Collection (1) · Blood Transfusion (1) · Cholecalciferol (1) · Colloids (1) · Crystalloid Solutions (1) · Docosahexaenoic Acids (1) · Drug Packaging (1)
Assiut University (6) · Medical University of Vienna (5) · University of Ulm (4) · Al-Nahrain University (3) · Medical University of Graz (3) · US Department of Veterans Affairs (3) · BG Trauma Center Tuebingen (2) · Isfahan University of Medical Sciences (2) · Masaryk Hospital Krajská zdravotní a.s. (2) · Masaryk University (2) · Nantes University Hospital (2) · Norwegian University of Science and Technology (2) · Oslo University Hospital (2) · Oxford University Hospitals NHS Trust (2) · Peking University People's Hospital (2)
United States (25) · Germany (12) · Austria (7) · Czechia (6) · France (6) · Switzerland (6) · United Kingdom (5) · Belgium (4) · Egypt (4) · Norway (4) · Turkey (Türkiye) (4) · Australia (3) · Canada (3) · Iran (3) · Iraq (3)
Jochen Hinkelbein, MD (2) · Manfred Weiss, MD, MBA (2) · A. Gerson Greenburg, MD, PhD (1) · Adem Az, M.D. (1) · Ajai Malhotra, MD (1) · Alberto F Garcia, MD MSc (1) · Alessandro Cartei, MD (1) · Alexandru Rogobete, MSc, PhDs, Clinical Researcher (1) · Anees K Nile, Professor of general surgery (1) · Arun Aneja, MD (1) · Arzu Karaveli (1) · Associate Professor Craig French (1)
PMID 31086450, PMID 33667204, PMID 39773175, PMID 11734620, PMID 12767787, PMID 15520972, PMID 15777856, PMID 16564618, PMID 1734842, PMID 17410508, PMID 17550344, PMID 17717368, PMID 18075402, PMID 18092558, PMID 18376168, PMID 18404076, PMID 18538928, PMID 19416436, PMID 19416437, PMID 19691153, PMID 19702423, PMID 19818031, PMID 19937992, PMID 20028830, PMID 20068467, PMID 20104399, PMID 20350705, PMID 20495473, PMID 21050322, PMID 21203519, PMID 21223493, PMID 21422095, PMID 21427372, PMID 21577147, PMID 22102646, PMID 22244896, PMID 22284159, PMID 2231804, PMID 22339896, PMID 22458247, PMID 22553896, PMID 22767074, PMID 22777514, PMID 23450051, PMID 23479227, PMID 23732264, PMID 23844754, PMID 24108515, PMID 24793256, PMID 24995300
2017 (1), K23DA052041 (1), R01GM120484 (1), R01MD006075 (1)