23 completed, 4 unknown, 3 terminated, 3 withdrawn. 37 Phase 2, 6 Phase 1, 4 Phase 3.
Follow Trauma: new trials by email Literature Review of Trauma trials Research Report on Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Cannabidiol and Neuroimaging on Stress Cannabidiol, Placebo - Early Life Adversity, Trauma | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 160 | 2025-10-29 | 2026-09-10 |
| Calcium Administration in Life-saving Management During Massive Hemorrhage calcium gluconate, Control: Placebo - Massive Hemorrhage, Trauma | Phase 2 / Phase 3 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 81 | 2025-05-01 | 2025-02-11 |
| CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial Calcium Gluconate, Vasopressin, saline placebo - Trauma, Hemorrhage | Phase 2 | Recruiting | Jason Sperry | 1050 | 2024-06-30 | 2026-09-29 |
| Role of Active Deresuscitation After Resuscitation: Furosemide Injection, Metolazone Tablets - Fluid Overload, Critical Illness | Phase 2 | Unknown | Unity Health Toronto | 120 | 2024-05-01 | 2024-03-22 |
| A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients EMPOWER, Supportive Conversation - Grief, Trauma | Phase 2 | Active not recruiting | Weill Medical College of Cornell University | 172 | 2022-10-11 | 2026-09-25 |
| Cold Stored Platelet in Hemorrhagic Shock Cold Stored Platelets (CSP), Standard Care - Trauma, Hemorrhage | Phase 2 | Completed | Jason Sperry | 200 | 2022-06-21 | 2024-12-18 |
| REmimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVID-19: REHSCU Study Remimazolam - Acute Respiratory Failure, COVID-19 | Phase 2 | Completed | Nantes University Hospital | 30 | 2020-11-30 | 2021-11-04 |
| MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome MultiStem, Placebo - Trauma, Adult Stem Cells | Phase 2 | Unknown | Healios K.K. | 156 | 2020-11-09 | 2024-05-24 |
| Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection - Muscle Atrophy, Surgery | Phase 2 / Phase 3 | Unknown | The Stone Research Foundation for Sports Medicine and Arthritis | 15 | 2020-05-08 | 2021-08-31 |
| Relieving Acute Pain (RAP) Study: A Pilot Study Oxycodone, Ketorolac, Placebo - Trauma, Opioid Use | Phase 2 | Terminated | University of Maryland, Baltimore | 3 | 2018-09-17 | 2021-04-27 |
| PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs ) Azithromycin, Albendazole, Ivermectin - Lymphatic Filariasis, Yaws | Phase 2 | Completed | Lihir Medical Centre | 42 | 2018-09-01 | 2019-02-28 |
| Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma Acellular Tissue Engineered Vessel (ATEV) - Trauma, Vascular System Injury | Phase 2 / Phase 3 | Completed | Humacyte, Inc. | 72 | 2018-09-01 | 2026-07-29 |
| Fibrinogen Early In Severe Trauma studY Junior Fibrinogen Concentrate, Cryoprecipitate - Trauma, Hemorrhage | Phase 2 | Unknown | Gold Coast Hospital and Health Service | 44 | 2018-07-01 | 2020-06-29 |
| Acellular Adipose Tissue (AAT) for Soft Tissue Reconstruction Acellular Adipose Tissue (AAT) - Soft Tissue Injuries, Trauma | Phase 2 | Completed | Johns Hopkins University | 15 | 2018-06-21 | 2026-05-12 |
| Low Dose Ketamine Intra Nasal Traumatology Ketamine, Placebo - Trauma | Phase 2 | Completed | University of Monastir | 1102 | 2018-01-01 | 2019-07-02 |
| Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients Tramadol, Metoclopramide, Placebo - Trauma, Opioid Analgesic Adverse Reaction | Phase 2 | Completed | University of Malaya | 191 | 2017-07-01 | 2017-12-26 |
| Fibrinogen Early In Severe Trauma studY Fibrinogen Concentrate, Cryoprecipitate - Trauma, Haemorrhage | Phase 2 | Completed | Gold Coast Hospital and Health Service | 100 | 2016-12-01 | 2018-03-05 |
| Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy VHA algorithm - Hemorrhage, Coagulopathy | Phase 2 | Completed | Queen Mary University of London | 412 | 2016-06-01 | 2018-08-29 |
| Dexmedetomidine Versus Propofol for Prolonged Sedation in Poly Traumatized Mechanically Ventilated Patients Dexmedetomidine, Propofol - Trauma | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2015-11-01 | 2016-08-23 |
| BraveMind: Advancing the Virtual Iraq/Afghanistan PTSD Exposure Therapy Virtual Reality Exposure Therapy (VRET) - Trauma, Post-Traumatic Stress Disorder | Phase 2 | Completed | Emory University | 15 | 2015-05-01 | 2017-08-09 |
Showing 20 of 37. Sign in to see all of them.
Wounds and Injuries (37) · Hemorrhage (8) · Hemostatic Disorders (5) · Shock, Hemorrhagic (4) · Sepsis (3) · Stress Disorders, Post-Traumatic (2) · Stroke (2) · Acidosis, Lactic (1) · Afibrinogenemia (1) · Anemia (1) · Anxiety Disorders (1) · Brain Injuries (1) · Burns (1) · COVID-19 (1) · Cleft Palate (1)
Pathological Conditions, Signs and Symptoms (15) · Pathologic Processes (13) · Cardiovascular Diseases (9) · Vascular Diseases (9) · Hemic and Lymphatic Diseases (7) · Hematologic Diseases (6) · Hemorrhagic Disorders (5) · Shock (5) · Signs and Symptoms (4) · Infections (3) · Inflammation (3) · Lung Diseases (3) · Mental Disorders (3) · Nervous System Diseases (3) · Respiratory Tract Diseases (3)
Fibrinogen (5) · Saline Solution (4) · Calcium Gluconate (2) · Propranolol (2) · Sodium Chloride (2) · Standard of Care (2) · cryoprecipitate coagulum (2) · Albendazole (1) · Azithromycin (1) · Calcium (1) · Cannabidiol (1) · Dexmedetomidine (1) · Diethylcarbamazine (1) · Docosahexaenoic Acids (1) · Ferric Oxide, Saccharated (1)
Denver Health and Hospital Authority (3) · Novo Nordisk A/S (3) · Gold Coast Hospital and Health Service (2) · Jason Sperry (2) · Assiut University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Critical Biologics Corporation (1) · Emory University (1) · Hamilton Health Sciences Corporation (1) · Healios K.K. (1) · Humacyte, Inc. (1) · Icahn School of Medicine at Mount Sinai (1) · Intermountain Health Care, Inc. (1) · Japan Science and Technology Agency (1) · Johns Hopkins University (1)
United States (16) · Germany (6) · Canada (5) · Australia (4) · France (4) · Israel (4) · United Kingdom (4) · Switzerland (3) · Austria (2) · Czechia (2) · Denmark (2) · Finland (2) · Italy (2) · Netherlands (2) · Norway (2)
Barbara O Rothbaum, PhD/ABPP (1) · Barto Nascimento, MD MSc (1) · Charles Cox, MD (1) · Christine Gaarder, MD (1) · Damon Cooney, MD, PhD (1) · Darnell Kaigler, DDS, PhD (1) · Dietmar Fries, Prof. MD (1) · Ernest E Moore, MD (1) · Frank Guyette, MD, MPH (1) · Frank V. Booth, BCh, FACS (1) · Fredric M Pieracci, MD, MPH (1) · Hala S Abdel-Ghaffar, MD (1) · Holly Prigerson, PhD (1) · Jakob Stensballe, MD, PhD (1)
PMID 18580208, PMID 15734783, PMID 16096533, PMID 16734808, PMID 16859505, PMID 17156226, PMID 17184516, PMID 17189115, PMID 17686152, PMID 18496183, PMID 20520307, PMID 21303552, PMID 21720194, PMID 23682548, PMID 25784527, PMID 26220293, PMID 26814938, PMID 27430210, PMID 28549445, PMID 29047413, PMID 30032977, PMID 31851290, PMID 32818264, PMID 33109923, PMID 35508351, PMID 36163263, PMID 37262040, PMID 38708880, PMID 39565635, PMID 40174701, PMID 40766812, PMID 40983029, PMID 41140335, PMID 42133624, PMID 42848323
2004 (1), 2014 (1), R01MH139940 (1), R01NR019831 (1), R03DK073349 (1)