38 completed, 13 unknown, 9 terminated, 7 recruiting. 18 Phase 3, 16 Phase 2, 15 Not applicable, 3 Phase 1, 1 Phase 4.
Follow Shock, Hemorrhagic: new trials by email Literature Review of Shock, Hemorrhagic trials Research Report on Shock, Hemorrhagic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Predictors of In-Hospital Mortality in Severe Abdominal Trauma Abdominal Injuries, Wounds and Injuries | Recruiting | Minia University | 430 | 2026-10-01 | 2026-10-02 | |
| Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients Hemorrhagic Shock, Pediatric Trauma | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-09-09 | |
| Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries. Crystalloid below 1000 mL., IV fluids more than 1,000 mL - Trauma and Emergency Care, Shock,Hemorrhagic | Not yet recruiting | Hospital Departamental de Villavicencio | 716 | 2026-10-01 | 2026-05-28 | |
| Inferior Vena Cava Versus Subclavian Vein Collapsibility for Predicting Fluid Responsiveness in Trauma Hemorrhagic Shock Hemorrhagic Shock, Trauma | Not yet recruiting | Assiut University | 120 | 2026-10-01 | 2026-09-14 | |
| Cryo-FIRST: Effectiveness of INTERCEPT Fibrinogen Complex (IFC) for Trauma-Associated Hemorrhage Pathogen Reduced Cryoprecipitated Fibrinogen Complex - Hypofibrinogenemia, Hemorrhage | Enrolling by invitation | Cerus Corporation | 320 | 2026-09-15 | 2026-10-14 | |
| Hemorrhagic Shock in Orthopedic Fractures Hemorrhagic Shock, Pelvic Fractures | Not yet recruiting | Sohag University | 250 | 2026-07-25 | 2026-07-10 | |
| Evaluation of Transthoracic Echocardiography Parameters and Their Changes in Blood Donor Volunteers Transthoracic Echocardiography measurements - Hemorrhage, Trauma | Not applicable | Completed | Centre Hospitalier Universitaire de Nīmes | 66 | 2025-10-02 | 2026-10-22 |
| Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock low-titer O-group whole blood, 1:1:1 component transfusion, ABO- and Rh-compatible whole blood - Hemorrhage, Hemorrhagic Shock | Phase 3 | Not yet recruiting | Xijing Hospital | 180 | 2025-09-01 | 2025-08-19 |
| REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam ResQFoam - Hemorrhagic Shock, Trauma | Not applicable | Recruiting | Arsenal Medical, Inc. | 40 | 2025-08-07 | 2025-11-10 |
| Biological and Clinical Relevance of Quantra Viscoelastic Hemostatic Assay in Hemorrhagic Cardiac Surgery Viscoelastometric hemostatic assay - Hemorrhage, Cardiac Surgery | Completed | Pitié-Salpêtrière Hospital | 600 | 2025-07-10 | 2026-04-20 | |
| Implementation of an Empiric Transfusion Bundle for Out of Hospital Patients With Haemorrhagic Shock Haemorrhagic Shock, Trauma Coagulopathy | Recruiting | Medical University of Graz | 10 | 2025-06-01 | 2025-12-17 | |
| Empiric Calcium in Massive Transfusion Calcium Gluconate - Hemorrhage, Trauma | Phase 3 | Withdrawn | University of California, Irvine | 2025-01-01 | 2026-03-30 | |
| Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children Low Titer Group O Whole Blood (LTOWB), Placebo, Tranexamic Acid (TXA) - Hemorrhagic Shock, Trauma Injury | Phase 3 | Recruiting | Philip Spinella | 1000 | 2024-11-01 | 2026-09-17 |
| Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days, Protonix (pantoprazole) 40 mg q 24 hrs for 2 days - Acute Kidney Injury | Phase 2 / Phase 3 | Recruiting | The University of Texas Health Science Center, Houston | 100 | 2024-09-07 | 2026-02-19 |
| Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock Crystalloid and blood as resuscitation, crystalloid, blood and low dose of norepinephrine - Mortality Rate, Hemorrhagic Shock | Not applicable | Completed | Tanta University | 60 | 2024-08-30 | 2025-07-11 |
| CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial Calcium Gluconate, Vasopressin, saline placebo - Trauma, Hemorrhage | Phase 2 | Recruiting | Jason Sperry | 1050 | 2024-06-30 | 2026-10-30 |
| Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma Multi-organ Failure After Severe Trauma | Unknown | Assistance Publique - Hôpitaux de Paris | 80 | 2024-06-27 | 2024-07-15 | |
| Evaluation of Endothelial Glycocalyx in the Surgical Resuscitation of Major Burn Patients Debridement Surgery, Sdc-1 Level Measurement - Syndecan 1, Severe Burn | Recruiting | Hospital Universitari Vall d'Hebron Research Institute | 40 | 2024-03-05 | 2024-11-01 | |
| Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock Low dose of Norepinephrine (NE), High dose of Norepinephrine (NE) - Norepinephrine, Hemorrhagic Shock | Not applicable | Unknown | Tanta University | 200 | 2023-12-01 | 2024-03-15 |
| Efficacy and Safety of Early Use PCC in Severe Trauma 4 factor Prothrombin Complex Concentrates - Severe Trauma, Traumatic Shock | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 380 | 2023-08-10 | 2026-04-20 |
Showing 20 of 79. Sign in to see all of them.
Wounds and Injuries (35) · Hemorrhage (22) · Shock (10) · Hemostatic Disorders (8) · Shock, Traumatic (8) · Multiple Trauma (7) · Accidental Injuries (6) · Brain Injuries, Traumatic (5) · Wounds, Penetrating (4) · Acidosis, Lactic (3) · Sepsis (3) · Shock, Septic (3) · Wounds, Nonpenetrating (3) · Acute Kidney Injury (2)
Pathological Conditions, Signs and Symptoms (79) · Pathologic Processes (78) · Shock (69) · Hemorrhage (57) · Wounds and Injuries (15) · Cardiovascular Diseases (11) · Vascular Diseases (10) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Hemorrhagic Disorders (9) · Brain Diseases (7) · Central Nervous System Diseases (7) · Nervous System Diseases (7) · Infections (6) · Brain Injuries (5)
Standard of Care (5) · Saline Solution (4) · Sodium Chloride (4) · Norepinephrine (3) · PEG-hemoglobin (3) · Resuscitation (3) · Ringer's Lactate (3) · Tranexamic Acid (3) · maleimide-polyethylene glycol-modified hemoglobin, MP4 (3) · Blood Specimen Collection (2) · Calcium Gluconate (2) · Erythrocyte Count (2) · Valproic Acid (2) · Vasopressins (2) · polynitroxylated pegylated hemoglobin (2)
Assiut University (4) · Jason Sperry (4) · Assistance Publique - Hôpitaux de Paris (3) · Sangart (3) · Dartmouth-Hitchcock Medical Center (2) · Denver Health and Hospital Authority (2) · Dr. Hasan Alam (2) · Haukeland University Hospital (2) · Tanta University (2) · The University of Texas Health Science Center, Houston (2) · University of Alabama at Birmingham (2) · University of California, Irvine (2) · University of California, San Francisco (2) · University of Maryland, Baltimore (2) · University of Washington (2)
United States (35) · France (12) · Canada (6) · Egypt (5) · Germany (5) · China (4) · Norway (4) · Australia (3) · Austria (3) · New Zealand (3) · South Africa (3) · Spain (3) · Switzerland (3) · United Kingdom (3) · Brazil (2)
Karim Brohi, MD (3) · Hasan Alam, MD (2) · Jan Jansen, MBBS, PhD (2) · Jason Sperry, MD (2) · Amy Goldberg, MD (1) · Bruce D Spiess, MD, FAHA (1) · Charles Van Way, III, M.D. (1) · David Hoyt, MD (1) · David T Neilipovitz, MD (1) · Dongsheng Zhou, MD, PhD (1)
PMID 25647203, PMID 26220293, PMID 38531812, PMID 40271704, PMID 17109736, PMID 18090009, PMID 19228496, PMID 21112053, PMID 21115374, PMID 21332727, PMID 21841534, PMID 22071998, PMID 22777113, PMID 23857856, PMID 24088993, PMID 24335442, PMID 24751831, PMID 24940804, PMID 24996573, PMID 25275593, PMID 25782753, PMID 25784523, PMID 25784527, PMID 25816119, PMID 25947955, PMID 26002260, PMID 26376142, PMID 26508436, PMID 26522327, PMID 26680132, PMID 26773077, PMID 28183347, PMID 28374096, PMID 28497259, PMID 28611888, PMID 28731937, PMID 28930959, PMID 29766088, PMID 29793591, PMID 30030268, PMID 30032977, PMID 30447946, PMID 31050809, PMID 31461138, PMID 31851290, PMID 31969168, PMID 32983160, PMID 33797501, PMID 34330462, PMID 34530886
U01HL077863 (2), 1UG3HL157401-01A1 (1), R34HL135224 (1), U24HL157310 (1)