8 completed, 2 terminated, 1 recruiting, 1 withdrawn. 12 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 8, Terminated 2, Recruiting 1, Withdrawn 1 |
| Phase 2 | 6 | Completed 5, Recruiting 1 |
Follow Trauma: new trials by email Literature Review of Trauma trials Research Report on Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Cannabidiol and Neuroimaging on Stress Cannabidiol, Placebo - Early Life Adversity, Trauma | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 160 | 2025-10-29 | 2026-09-10 |
| Dexamethasone as an Immediate Intervention Dexamethasone - Trauma | Phase 1 | Withdrawn | NYU Langone Health | 2017-01-01 | 2017-12-14 | |
| A Study to Evaluate the Safety and Tolerability of Valproic Acid in Trauma Patients(Part 2) Valproic Acid, Isotonic saline solution - Shock,Hemorrhagic, Trauma | Phase 1 | Terminated | Dr. Hasan Alam | 1 | 2016-11-01 | 2017-11-06 |
| Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST) Fibrinogen concentrate, Placebo Comparator - Trauma, Injury | Phase 1 / Phase 2 | Completed | Sunnybrook Health Sciences Centre | 50 | 2014-10-01 | 2016-04-14 |
| Cell Therapy for Craniofacial Bone Defects Ixmyelocel-T, Autogenous Bone Grafting - Cleft Palate, Trauma | Phase 1 / Phase 2 | Completed | University of Michigan | 18 | 2012-08-01 | 2017-05-04 |
| Fibrinogen Concentrate (FGTW) in Trauma Patients, Presumed to Bleed (FI in TIC) Human Fibrinogen Concentrate, Placebo - Trauma, Massive Hemorrhage | Phase 1 / Phase 2 | Completed | Medical University Innsbruck | 67 | 2011-09-01 | 2015-12-08 |
| Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-01 Study Omega-3 Polyunsaturated Fatty Acid - Trauma, Posttraumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Japan Science and Technology Agency | 15 | 2008-05-01 | 2012-07-03 |
| Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels rhu-pGelsolin, Placebo - Low Gelsolin, Trauma | Phase 1 / Phase 2 | Completed | Critical Biologics Corporation | 40 | 2008-03-01 | 2010-09-29 |
| Correlation Research Study: IQ2, NcIQ and IQ101 Noninvasive Hemodynamic Patient Monitor - Heart Failure, Dyspnea | Phase 1 | Completed | Noninvasive Medical Technologies, Inc. | 25 | 2007-06-01 | 2007-06-26 |
| Enteral Glutamine Supplementation for the Patient With Major Torso Trauma Glutamine - Trauma, Critical Illness | Phase 1 | Terminated | The University of Texas Health Science Center, Houston | 20 | 2005-06-01 | 2010-04-23 |
| GW406381 In Patients With Peripheral Nerve Injury GW406381 - Hyperalgesia, Neurodynia | Phase 1 | Completed | GlaxoSmithKline | 40 | 2003-09-01 | 2009-02-23 |
| Adjuvant Nutrition for Critically Ill Trauma Patients Juven (nutritional), HMB (nutritional) - Trauma | Phase 1 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 100 | 2003-03-01 | 2010-01-14 |
Wounds and Injuries (12) · Afibrinogenemia (1) · Anxiety Disorders (1) · Burns (1) · Cleft Palate (1) · Combat Disorders (1) · Critical Illness (1) · Dyspnea (1) · Emergencies (1) · Heart Failure (1) · Hemorrhage (1) · Hemostatic Disorders (1) · Hyperalgesia (1) · Hypertension (1) · Infections (1)
Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (5) · Mental Disorders (3) · Cardiovascular Diseases (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disease Attributes (2) · Respiratory Tract Diseases (2) · Shock (2) · Signs and Symptoms (2) · Stress Disorders, Traumatic (2) · Trauma and Stressor Related Disorders (2) · Vascular Diseases (2) · Blood Coagulation Disorders (1) · Blood Coagulation Disorders, Inherited (1) · Coagulation Protein Disorders (1)
Fibrinogen (2) · Cannabidiol (1) · Dexamethasone (1) · Docosahexaenoic Acids (1) · GW406381X (1) · Glutamine (1) · Saline Solution (1) · Valproic Acid (1)
Critical Biologics Corporation (1) · Dr. Hasan Alam (1) · GlaxoSmithKline (1) · Icahn School of Medicine at Mount Sinai (1) · Japan Science and Technology Agency (1) · Medical University Innsbruck (1) · NYU Langone Health (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Noninvasive Medical Technologies, Inc. (1) · Sunnybrook Health Sciences Centre (1) · The University of Texas Health Science Center, Houston (1) · University of Michigan (1)
United States (6) · Austria (1) · Canada (1) · Czechia (1) · Germany (1) · Hong Kong (1) · Japan (1) · United Kingdom (1)
Barto Nascimento, MD MSc (1) · Darnell Kaigler, DDS, PhD (1) · David Seaberg, MD (1) · Dietmar Fries, Prof. MD (1) · Hasan Alam, MD (1) · Isaac Galatzer-Levy, MD (1) · John A Rathmacher, Ph.D. (1) · Joseph A Tyndall, MD (1) · Keren Bachi, PhD (1) · Kevin Ferguson, MD (1) · Margaret M McQuiggan, MS, RD, CNSD (1) · Richard C Straube, MD (1) · Selene Tam, PhD (1) · Wai M Chan, MBBS (1)
PMID 20520307, PMID 21303552, PMID 21720194, PMID 33109923
M01RR002558 (1), R01MH139940 (1), R43DK061818 (1)