49 completed, 22 unknown, 10 not yet recruiting, 7 recruiting. 43 Not applicable, 16 Phase 4, 10 Phase 2, 9 Phase 3, 3 Phase 1.
Follow Tonsillectomy: new trials by email Literature Review of Tonsillectomy trials Research Report on Tonsillectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine in Tonsillectomy for Opioid-sparing Pain Management Suzetrigine, Acetaminophen, oxycodone - Tonsillectomy, Pharyngoplasty | Phase 4 | Not yet recruiting | Stanford University | 58 | 2026-11-01 | 2026-09-16 |
| Coblator Wand Comparative Analysis New Coblator Ablation Wands, Reprocessed Medline Coblator Ablation Wands - Tonsillectomy, Adenoidectomy | Not applicable | Recruiting | Montefiore Medical Center | 30 | 2026-10-01 | 2026-09-29 |
| Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy Sphenopalatine ganglion block (Ropivacaine), Sham sphenopalatine ganglion block (Saline) - Postoperative Pain, Tonsillectomy | Phase 4 | Not yet recruiting | Vinícius C Quintão, MD, MSc, PhD | 145 | 2026-09-15 | 2026-08-28 |
| Effect of Preoprative Nebulized Dexmedetomidine Compared to Nebulized Lidocaine in Attenuating Sore Throat Following Tonsillectomy In Childern. Group D (dexmedetomidine group), Group L (Lidocaine group) - Sore Throat, Dexmedetomidine Analgesia | Not applicable | Recruiting | Fayoum University Hospital | 70 | 2026-09-01 | 2026-08-21 |
| Postoperative Care After Tonsillectomy Nutrition and Hydration - Tonsillectomy, Bleeding | Phase 3 | Not yet recruiting | Hospital Felicio Rocho | 300 | 2026-09-01 | 2026-08-28 |
| Topical Magnesium Sulfate Versus Peritonsillar Bupivacaine for Post-Tonsillectomy Pain Relief in Children Magnesium Sulfate, Bupivacaine - Post-tonsillectomy Pain, Tonsillectomy | Phase 4 | Not yet recruiting | Assiut University | 40 | 2026-09-01 | 2026-08-12 |
| Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening EEG-guided, Standard - Pediatric Anesthesia, Emergence Delirium, Anesthesia | Not applicable | Completed | Pontificia Universidad Catolica de Chile | 50 | 2026-06-23 | 2026-09-08 |
| Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR Drug therapy (NASONEX nasal spray), Adenoidectomy, Adenotonsillectomy - Adenoidectomy, Tonsillectomy | Not applicable | Not yet recruiting | Tongji Hospital | 36 | 2026-04-11 | 2026-04-14 |
| Screen-delivered Augmented-reality Preparation and Anxiety Before Pediatric Adenotonsillectomy in China Screen-delivered augmented-reality group, Usual Care Group - Tonsillectomy, Preoperative Care | Not applicable | Completed | Central South University | 100 | 2026-04-04 | 2026-08-12 |
| Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy Ondansetron lozenge, Ondansetron intravenous - Ondansetron, Lozenge | Not applicable | Recruiting | Tanta University | 210 | 2026-03-25 | 2026-03-27 |
| Melatonin vs Midazolam in Children Undergoing Tonsillectomy Melatonin group, Midazolam group, Control group - Emergence Delirium, Anesthesia, Child | Phase 3 | Not yet recruiting | Ain Shams University | 195 | 2026-03-01 | 2026-01-13 |
| Head-Only Draping in Pediatric Tonsillectomy Full-Body Surgical Draping, Head-Only Surgical Draping - Tonsillectomy, Infections | Not applicable | Not yet recruiting | NYU Langone Health | 200 | 2026-02-02 | 2026-01-16 |
| Lateral Positioning for Extubation After Adenotonsillectomy lateral postion, supine position - Perioperative Respiratory Adverse Events, Adenoidectomy | Not applicable | Not yet recruiting | Sichuan University | 350 | 2025-08-20 | 2025-08-06 |
| Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children Etomidate and fentanyl group, Etomidate and esketamine group - Etomidate, Esketamine | Not applicable | Not yet recruiting | Anqing Municipal Hospital | 64 | 2025-07-10 | 2025-07-14 |
| Weight-Adjusted Diclofenac Potassium Medicated Lollipop for Post-Adenotonsillectomy Pain in Children Diclofenac Potassium Medicated Lollipop - Post Operative Analgesia, Tonsillectomy | Not applicable | Completed | Hospital Universitario de Caracas | 50 | 2025-05-01 | 2026-06-16 |
| SUPRATHEL 250 as a Treatment for Oropharyngeal Wounds Suprathel 250, Comparator - Tonsillitis, Tonsillectomy | Not applicable | Recruiting | Alaa Emara | 80 | 2025-04-30 | 2026-07-27 |
| Evaluating the Efficacy of Intravenous Acetaminophen (IV Tylenol) in Reducing Pain and Agitation in Pediatric Patients Undergoing Elective Tonsillectomy and/or Adenoidectomy No Intervention: Observational Cohort - Tonsillectomy, Adenoidectomy | Enrolling by invitation | MetroHealth Medical Center | 20 | 2025-04-21 | 2026-05-08 | |
| Comparsion of Intravenous Injection of Magnesium Sulfate and Lidocaine Effectiveness on the Prevention of Laryngospasm and Analgesic Requirement in Tonsillectomy magnsium sulfate, Lidocaine (drug), Saline - Tonsillectomy | Phase 3 | Not yet recruiting | Assiut University | 90 | 2025-03-01 | 2025-01-07 |
| Suprazygomatic Nerve Block in Tonsillectomy Patients Suprazygomatic maxillary nerve block using dexmedetomidne and Bupivacaine, Suprazygomatic maxillary nerve block using Bupivacaine - Tonsillectomy | Not applicable | Unknown | Assiut University | 80 | 2024-10-22 | 2024-04-11 |
| THE EFFECT OF SANDPLAY THERAPY ON THE ANXİETY AND PAİN LEVELS OF CHİLDREN DURİNG PREOPERATİVE PERİOD Sand Play Therapy - Tonsillectomy, Postoperative Pain | Not applicable | Completed | Ondokuz Mayıs University | 68 | 2024-10-01 | 2026-02-25 |
Showing 20 of 95. Sign in to see all of them.
Pain, Postoperative (17) · Pain (11) · Hemorrhage (7) · Agnosia (4) · Anxiety Disorders (4) · Emergence Delirium (4) · Postoperative Complications (4) · Postoperative Hemorrhage (4) · Tonsillitis (4) · Sleep Apnea, Obstructive (3) · Drug-Related Side Effects and Adverse Reactions (2) · Otorhinolaryngologic Diseases (2) · Sleep Apnea Syndromes (2) · Acute Pain (1) · Arnold-Chiari Malformation (1)
Pathological Conditions, Signs and Symptoms (40) · Signs and Symptoms (32) · Neurologic Manifestations (30) · Pathologic Processes (30) · Postoperative Complications (23) · Pain (14) · Nervous System Diseases (13) · Respiratory Tract Diseases (11) · Neurobehavioral Manifestations (8) · Mental Disorders (7) · Infections (6) · Otorhinolaryngologic Diseases (6) · Respiratory Tract Infections (6) · Pharyngeal Diseases (5) · Stomatognathic Diseases (5)
Saline Solution (8) · Acetaminophen (6) · Sodium Chloride (6) · Standard of Care (6) · Tonsillectomy (6) · Bupivacaine (5) · Dexamethasone (5) · Dexmedetomidine (4) · Ketamine (3) · Midazolam (3) · Ropivacaine (3) · Celecoxib (2) · Epinephrine (2) · Gabapentin (2) · Honey (2)
Assiut University (4) · Children's Hospital of Philadelphia (2) · Hospital Universitario de Caracas (2) · Kasr El Aini Hospital (2) · Medtronic - MITG (2) · Vanderbilt University Medical Center (2) · Ain Shams University (1) · Alaa Emara (1) · Anqing Municipal Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Ayse Sonay Turkmen, Prof.Dr (1) · Baylor College of Medicine (1) · Central South University (1) · Centre Hospitalier Universitaire Dijon (1) · Centre Hospitalier Universitaire de Besancon (1)
United States (31) · China (6) · Turkey (Türkiye) (6) · France (5) · Egypt (4) · Sweden (3) · Brazil (2) · Canada (2) · Denmark (2) · Germany (2) · Israel (2) · Italy (2) · Venezuela (2) · Austria (1) · Belgium (1)
Abdulhadi Al'Saflan, MD (1) · Alaa Emara (1) · Alaa M. Khidr, MD (1) · Alex Van Hoorn, MD (1) · Ana Menezes (1) · Andrea Cassone, RN, BSN MES (1) · Art P Wheeler, MD (1) · Cathy Lammers, MD (1) · Christina Calamaro, PhD, CPNP-PC (1) · Christopher J Hartnick, MD (1) · Daniel L Price, MD (1) · Dina Mohamed (1) · Elizabeth Card, MSN (1) · Emine Aysu Salviz, Assoc. Prof. (1)
PMID 22235871, PMID 16929992, PMID 18983373, PMID 19294964, PMID 19841335, PMID 20069307, PMID 20090434, PMID 20564474, PMID 21812940, PMID 21951354, PMID 21994191, PMID 22344711, PMID 22500063, PMID 22704676, PMID 23385384, PMID 24281921, PMID 24366615, PMID 24815964, PMID 25215457, PMID 25515059, PMID 25846344, PMID 26956620, PMID 27020269, PMID 28289832, PMID 28372527, PMID 28598766, PMID 28815308, PMID 29574597, PMID 29912819, PMID 30702436, PMID 30946442, PMID 32247766, PMID 32618627, PMID 33394138, PMID 33640801, PMID 34304234, PMID 34338876, PMID 35412873, PMID 35672942, PMID 35771572, PMID 36627154, PMID 37231477, PMID 38018707, PMID 38303681, PMID 38666175, PMID 38916221, PMID 40934240, PMID 41083818, PMID 41862716, PMID 42053523
2019 (3), 2025 (1), K08DA048110 (1), R01HD037007 (1), R01NR004826 (1)