36 completed, 20 unknown, 12 recruiting, 5 not yet recruiting. 79 Phase 3, 12 Phase 2.
Follow Surgery: new trials by email Literature Review of Surgery trials Research Report on Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer Apatinib Mesylate Tablets - Gastric Cancer, Surgery | Phase 3 | Not yet recruiting | Fujian Medical University | 118 | 2026-12-25 | 2026-01-02 |
| Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Morphine-rachi Analgesia rachi morphine anesthesia, laparotomy, Lidocaine IV - Digestive System Disease, Surgery | Phase 3 | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 76 | 2026-09-01 | 2026-08-25 |
| Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery. PAI, PAI + steroid, PAI + zilretta - Knee Osteoarthritis, Musculoskeletal Disease | Phase 2 / Phase 3 | Recruiting | Walter Reed National Military Medical Center | 240 | 2026-09-01 | 2026-08-19 |
| Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt cisplatin based neoadjuvant chemotherapy, Radical cystectomy alone - Muscle-Invasive Bladder Carcinoma, Chemotherapy Effect | Phase 3 | Active not recruiting | Regina Elena Cancer Institute | 236 | 2026-08-13 | 2026-08-17 |
| Neoadjuvant SF-SBRT Plus Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC. Stereotactic body radiotherapy (SBRT), neoadjuvant immunotherapy, Neoadjuvant Chemotherapy - Non Small Cell Lung Cancer, Stereotactic Body Radiotherapy | Phase 3 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 201 | 2026-05-01 | 2026-05-29 |
| Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial Desmopressin Injectable Solution, Tranexamic Acid Injectable Product, Placebo - Chronic Kidney Diseases, Acute Kidney Injury | Phase 3 | Recruiting | Hamilton Health Sciences Corporation | 100 | 2025-06-09 | 2026-05-22 |
| Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients? IV magnesium sulfate, Placebo - Brain Tumor, Surgery | Phase 3 | Unknown | Thomas Jefferson University | 110 | 2024-11-01 | 2023-04-12 |
| Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial Ferric carboxymaltose, Placebo - Surgery, Liver Metastases | Phase 3 | Recruiting | Jon Unosson | 338 | 2024-09-04 | 2024-10-21 |
| Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block Ropivacaine 0.5% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.75% Injectable Solution - Nerve Block, Anesthesia, Local | Phase 3 | Completed | Nordsjaellands Hospital | 78 | 2024-04-18 | 2025-02-17 |
| Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC FOLFIRINOX or gemcitabine-nab-paclitaxel - Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma | Phase 3 | Recruiting | Sahlgrenska University Hospital | 432 | 2023-10-18 | 2024-12-03 |
| Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo Sugammadex, Placebo - Surgery | Phase 3 | Completed | Endeavor Health | 74 | 2023-07-03 | 2026-05-04 |
| Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection mesh, non-mesh - Neoplasms Malignant, Rectal Cancer | Phase 3 | Recruiting | Blokhin's Russian Cancer Research Center | 142 | 2023-06-05 | 2024-08-07 |
| COLLISION RELAPSE Trial Neoadjuvant systemic therapy (CAPOX+/-B FOLFOX+/-B FOLFIRI+/-B), Repeat local treatment - Colorectal Cancer, Liver Metastases | Phase 3 | Recruiting | Amsterdam UMC, location VUmc | 360 | 2023-04-24 | 2023-05-17 |
| NO During CPB in Neonates to Reduce Risk of AKI Nitric Oxide, Oxygen - AKI, CHD - Congenital Heart Disease | Phase 3 | Recruiting | Children's Hospital Medical Center, Cincinnati | 40 | 2023-01-10 | 2026-08-05 |
| 3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection - Gastric Cancer, Surgery | Phase 3 | Recruiting | Fujian Medical University | 702 | 2023-01-03 | 2024-06-24 |
| Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II) Intensified post-discharge surveillance, Standard post-discharge surveillance - Surgery, Cancer | Phase 3 | Active not recruiting | Fox Chase Cancer Center | 526 | 2022-10-14 | 2026-09-21 |
| Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS Ferric Derisomaltose Injection, Normal saline - Gynecologic Cancer, Anemia, Iron Deficiency | Phase 3 | Unknown | Alberta Health Services, Calgary | 82 | 2022-09-30 | 2022-07-20 |
| THRIVE Feasibility Trial Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent - Surgery--Complications, Anesthesia Complication | Phase 3 | Completed | Washington University School of Medicine | 300 | 2022-09-29 | 2023-11-24 |
| Bevonescein for Intra-Operative Nerve Visualization in Head and Neck Surgery Bevonescein, Intraoperative Visualization using White Light Reflectance (WLR) with Fluorescence (FL) Overlay, Intra-operative Visualization using White Light Reflectance (WLR) - Surgery | Phase 3 | Completed | Alume Biosciences, Inc. | 154 | 2022-04-29 | 2026-10-08 |
| Clinical Outcome of Palliative Surgery After Translational Therapy for Metastatic Gastric Cancer Versus Maintenance Chemotherapy for Metastatic Gastric Cancer Palliative surgery after translational therapy, Chemotheraoy along - Metastatic Gastric Cancer, Surgery | Phase 3 | Not yet recruiting | Fujian Medical University | 120 | 2022-04-01 | 2022-04-01 |
Showing 20 of 79. Sign in to see all of them.
Neoplasms (7) · Stomach Neoplasms (6) · Agnosia (4) · Colorectal Neoplasms (4) · Inflammation (4) · Pain, Postoperative (4) · Postoperative Complications (4) · Hemorrhage (3) · Pancreatic Neoplasms (3) · Rectal Neoplasms (3) · Cataract (2) · Depression (2) · Esophageal Neoplasms (2) · Nervous System Diseases (2) · Pain (2)
Neoplasms by Site (28) · Pathological Conditions, Signs and Symptoms (28) · Neoplasms (27) · Pathologic Processes (24) · Digestive System Diseases (23) · Digestive System Neoplasms (20) · Gastrointestinal Diseases (17) · Gastrointestinal Neoplasms (16) · Signs and Symptoms (10) · Intestinal Diseases (9) · Intestinal Neoplasms (8) · Neurologic Manifestations (8) · Nervous System Diseases (7) · Postoperative Complications (7) · Rectal Diseases (7)
Saline Solution (6) · Tranexamic Acid (4) · chlorhexidine gluconate (4) · Dexamethasone (3) · Acetaminophen (2) · Capecitabine (2) · Ketorolac (2) · Morphine (2) · Neoadjuvant Therapy (2) · R-1,1,1-trifluoro-4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-4-methyl-2-(((2-methyl-5-quinolyl)amino)methyl)pentan-2-ol (2) · Radiotherapy (2) · Sodium Chloride (2) · Sugammadex (2) · Aminocaproic Acid (1) · Analgesia, Patient-Controlled (1)
Medline Industries (4) · Fujian Medical University (3) · Amsterdam UMC, location VUmc (2) · Bausch & Lomb Incorporated (2) · Fresenius Kabi (2) · Fudan University (2) · Shanghai Pulmonary Hospital, Shanghai, China (2) · Sun Yat-sen University (2) · Sunnybrook Health Sciences Centre (2) · University Hospital, Grenoble (2) · Washington University School of Medicine (2) · Ain Shams University (1) · Alberta Health Services, Calgary (1) · Alume Biosciences, Inc. (1) · BIRENDRA KUMAR SAH (1)
United States (22) · China (17) · France (8) · Brazil (5) · Canada (3) · Italy (3) · Denmark (2) · Netherlands (2) · Spain (2) · Sweden (2) · Argentina (1) · Australia (1) · Belgium (1) · Colombia (1) · Egypt (1)
Paul Karanicolas, MD PhD (2) · Ahmed N El-Shaer, PhD (1) · Andreas Obermair, Prof (1) · Andrew G Hill, MBChB MD FRACS (1) · Antonio M. Lacy, MD, PhD (1) · Bahaa El-Din E Ali, PhD (1) · Belal N Khalil, M.Sc (1) · Brett Berman MD FACC (1) · C Beausoleil (1) · Chang-ming Huang (1) · Christian Rothe, PhD (1) · Colin Sietses, MD, PhD (1) · David H. Chi, MD (1) · E. Sander Connolly, M.D. (1) · Elena Rangelova, PhD (1)
PMID 10470696, PMID 11157016, PMID 12456412, PMID 12944571, PMID 15273542, PMID 15814643, PMID 16518661, PMID 17116130, PMID 17156221, PMID 17725736, PMID 18306479, PMID 18779478, PMID 19826360, PMID 20442260, PMID 21502557, PMID 23095627, PMID 23132508, PMID 23361105, PMID 23812286, PMID 23849573, PMID 25559811, PMID 26579498, PMID 26936365, PMID 27154151, PMID 27765582, PMID 27871504, PMID 28935558, PMID 29395821, PMID 30203101, PMID 30234517, PMID 30464493, PMID 30554184, PMID 30717805, PMID 31155459, PMID 31315670, PMID 31516975, PMID 31806506, PMID 31818843, PMID 31839089, PMID 32201572, PMID 32360052, PMID 32464476, PMID 32962936, PMID 33279544, PMID 33482865, PMID 33553366, PMID 34465477, PMID 34728527, PMID 34932836, PMID 34996918
2014 (1), 2015 (1), 2025 (1), R01NR017916 (1)