12237 completed, 5160 unknown, 3545 recruiting, 1969 terminated. 8011 Not applicable, 6031 Phase 2, 3156 Phase 1, 2530 Phase 3, 1110 Phase 4.
Follow Gastrointestinal Diseases: new trials by email Literature Review of Gastrointestinal Diseases trials Research Report on Gastrointestinal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis | Phase 4 | Not yet recruiting | Bausch Health Americas, Inc. | 100 | 2029-06-01 | 2026-10-06 |
| Bilio-pancreatic Complications of Congenital Duodenal Obstructions duodenal atresia - Duodenal Obstruction | Not yet recruiting | University Hospital, Angers | 450 | 2028-12-01 | 2026-02-10 | |
| Adaptive Neoadjuvant Therapy for Esophageal Cancer Neoadjuvant concurrent chemoradiotherapy - Esophageal Carcinoma, Neoadjuvant Therapy | Not applicable | Enrolling by invitation | Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center | 43 | 2028-03-01 | 2025-05-25 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp Shared Decision Making using a Patient Decision Aid. - Shared Decision Making, Colonic Polyp | Phase 2 | Not yet recruiting | Vejle Hospital | 110 | 2028-02-01 | 2026-04-30 |
| AI-Enabled Mobile App for Safe Eating in Older Adults With Dysphagia AI-Enabled Mobile Application plus Standard Care, Standard Dysphagia Education - Deglutition Disorders, Dysphagia | Not applicable | Not yet recruiting | KAM Chi Shan Anna | 332 | 2028-01-01 | 2026-09-23 |
| Methadone as an Alternative Treatment for Children Underdoing HSCT PCA plus methadone (Experimental), PCA Alone (SOC) - Leukemia, Aplastic Anemia | Phase 3 | Suspended | University of Texas Southwestern Medical Center | 60 | 2028-01-01 | 2025-10-23 |
| ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 50 | 2028-01-01 | 2026-02-09 |
| CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer CA102N, TAS-102, Bevacizumab - Metastatic Colorectal Cancer | Phase 2 | Suspended | Holy Stone Healthcare Co., Ltd | 100 | 2027-12-01 | 2026-09-18 |
| Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer intravoxel incoherent motion magnetic resonance imaging - Rectal Neoplasms, Prognosis | Not yet recruiting | Sichuan Cancer Hospital and Research Institute | 400 | 2027-11-01 | 2025-12-08 | |
| Liver Steatosis in Pediatric CD Patients Gluten-free diet - Celiac Disease in Children, Non-Alcoholic Fatty Liver Disease | Recruiting | University of Palermo | 91 | 2027-11-01 | 2026-05-01 | |
| Oral Fosamprenavir for GERD Fosamprenavir Calcium 700 MG Oral Tablet, Placebo - Refractory Gastroesophageal Reflux Disease, Gastroesophageal Reflux Disease | Phase 2 | Not yet recruiting | Medical College of Wisconsin | 60 | 2027-10-01 | 2026-09-10 |
| DESIR. Evaluation of the Pre-therapeutic Activity of Dihydropyrimidine dEShydrogenase (DPD) in Patients With Cancer and/or Renal Failure blood sampling, Blood sampling - Renal Impairment, Digestive Cancers | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 742 | 2027-10-01 | 2026-11-02 | |
| A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis) | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 70 | 2027-09-01 | 2026-09-08 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis | Not applicable | Not yet recruiting | Montefiore Medical Center | 40 | 2027-07-01 | 2026-09-14 |
| Parent Implemented Oral Nutrition, Eating, and Esophageal Reflexes Reintegration Protocol: RCT PIONEER Protocol - Deglutition Disorders in Infants, Chronic Tube Feeding in Hospitalized Infants | Not applicable | Not yet recruiting | Nationwide Children's Hospital | 130 | 2027-07-01 | 2026-08-28 |
| Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma Pembrolizumab and either Capcecitabine + Oxaliplatin or Oxaliplatin+Leucovorin + 5-fluorouracil - Gastric Cancer, Gastroesophageal-junction Cancer | Phase 3 | Not yet recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 820 | 2027-06-30 | 2026-09-29 |
| Analysis of the Role of the Microbiota in Diverticular Disease Diverticular Disease of Colon, Acute Diverticulitis | Not yet recruiting | Hospital of Navarra | 285 | 2027-06-01 | 2026-09-02 | |
| Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue | Not applicable | Not yet recruiting | University Hospital, Grenoble | 120 | 2027-06-01 | 2026-09-11 |
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Colorectal Neoplasms (6126) · Stomach Neoplasms (3179) · Colonic Neoplasms (2382) · Rectal Neoplasms (2239) · Crohn Disease (1947) · Esophageal Neoplasms (1843) · Colitis, Ulcerative (1793) · Inflammatory Bowel Diseases (1548) · Gastroesophageal Reflux (1174) · Breast Neoplasms (1017) · Irritable Bowel Syndrome (995) · Neoplasms (969) · Deglutition Disorders (836) · Pancreatic Neoplasms (817) · Carcinoma, Non-Small-Cell Lung (731)
Digestive System Diseases (26377) · Intestinal Diseases (17032) · Digestive System Neoplasms (14392) · Neoplasms by Site (14370) · Neoplasms (14114) · Gastrointestinal Neoplasms (13766) · Colonic Diseases (10791) · Intestinal Neoplasms (9352) · Rectal Diseases (8696) · Gastroenteritis (5526) · Pathological Conditions, Signs and Symptoms (5432) · Esophageal Diseases (5100) · Stomach Diseases (3991) · Colorectal Neoplasms (3233)
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National Cancer Institute (NCI) (326) · Fudan University (256) · Mayo Clinic (243) · AstraZeneca (213) · Sun Yat-sen University (210) · M.D. Anderson Cancer Center (193) · Assiut University (183) · Takeda (175) · Memorial Sloan Kettering Cancer Center (172) · Chinese University of Hong Kong (155) · Pfizer (145) · National Taiwan University Hospital (136) · Hoffmann-La Roche (131) · Assistance Publique - Hôpitaux de Paris (129) · Massachusetts General Hospital (128)
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PMID 40243391, PMID 33538338, PMID 35623069, PMID 24275240, PMID 40357993, PMID 26808342, PMID 22825366, PMID 36306483, PMID 40013523, PMID 40341124, PMID 15496622, PMID 24533607, PMID 25430806, PMID 29380251, PMID 32445184, PMID 35588252, PMID 37162250, PMID 19735233, PMID 30207593, PMID 15273542, PMID 25625764, PMID 25694210, PMID 26893500, PMID 27144617, PMID 31268130, PMID 33356421, PMID 35648151, PMID 36124702, PMID 37368103, PMID 40340830, PMID 20354937, PMID 20728210, PMID 21129076, PMID 22646630, PMID 26049686, PMID 26187751, PMID 28712102, PMID 29850873, PMID 30476584, PMID 30679026, PMID 30739254, PMID 31077827, PMID 31378656, PMID 31599001, PMID 32816215, PMID 32816630, PMID 33684552, PMID 35792493, PMID 36342120, PMID 36526796
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