1232 completed, 285 terminated, 272 recruiting, 134 active not recruiting. 890 Not applicable, 432 Phase 2, 332 Phase 1, 97 Phase 3, 84 Phase 4.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognitive Neurocomputational Task Reliability and Clinical Applications Consortium: Study 2 Motion Perception Task, Sine Wave Speech Task, Volatility Task - SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder | Not applicable | Not yet recruiting | Washington University School of Medicine | 325 | 2028-04-01 | 2026-10-15 |
| TeamTalk: Improving Inter-professional Communication During Cancer Treatment Multi-level communication intervention - Pediatric Cancer | Not applicable | Not yet recruiting | Washington University School of Medicine | 8 | 2027-09-23 | 2026-01-07 |
| Communication and Hospice Online With Optimal Support and Engagement Intermittent Hospice Team Support, Online Support Group with untrained facilitator, Online Support Group with trained facilitator - Caregivers, Family Caregivers | Not applicable | Not yet recruiting | Washington University School of Medicine | 567 | 2027-02-01 | 2026-08-14 |
| Semaglutide for Low Back Pain Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector) - Lower Back Pain, Obesity (BMI>30) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 250 | 2027-02-01 | 2026-07-28 |
| Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath Tumor avutometinib capsule + defactinib tablet - MPNST (Malignant Peripheral Nerve Sheath Tumor) | Phase 2 | Not yet recruiting | Girish Dhall, MD | 23 | 2027-01-01 | 2026-08-04 |
| Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management Contingency Management, Social Drivers of Health Screening - Pregnancy, Substance Use Disorder (SUD) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 245 | 2027-01-01 | 2026-08-20 |
| Social Media and Risk-reduction Training for Preterm Infant Care Practices Safe Sleep NICU Quality Improvement Campaign, Shared Reading NICU Quality Improvement Campaign, Safe Sleep TodaysNICUBaby videos and messages - Safe Sleep Education, SUID | Not applicable | Not yet recruiting | University of Massachusetts, Worcester | 1600 | 2027-01-01 | 2026-05-13 |
| Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer Telaglenastat, Radiation treatment, Cisplatin - Advanced Cervical Carcinoma, Cervical Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 42 | 2026-12-31 | 2026-09-03 |
| Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer Dabrafenib, Trametinib, Pembrolizumab - Anaplastic Thyroid Carcinoma, Thyroid Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-12-31 | 2026-10-21 |
| MIRICURE: Mirikizumab With Curettage and Repair (Closure) for Perianal Fistulizing Crohn's Disease Mirikizumab, Fistula Tract Curettage and Closure - Crohn's Disease, Perianal Fistula | Phase 4 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 50 | 2026-12-01 | 2026-08-24 |
| Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma Cemiplimab, Prednisone, Sirolimus - Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 22 | 2026-11-30 | 2026-10-15 |
| Synthetic Electrospun Fiber Matrix in Abdominal Wall Donor Sites for Breast Reconstruction Restrata® - Breast Reconstruction, Deep Inferior Epigastric Perforator | Not applicable | Not yet recruiting | Washington University School of Medicine | 20 | 2026-11-30 | 2026-10-01 |
| Sipuleucel-T (Sip-T) in Combination With N-803 in Metastatic Androgen Pathway Modulation Resistant (mAPMR) Prostate Cancer Sipuleucel-T, N803 - Prostate Cancer, Metastatic Prostate Cancer | Phase 1 | Not yet recruiting | Washington University School of Medicine | 30 | 2026-11-30 | 2026-08-10 |
| Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas NeuroBlate® Laser Ablation Laser Interstitial Thermal Therapy, Cemiplimab, Chemotherapy - Glioblastoma, Glioblastoma, IDH-wildtype | Phase 2 | Not yet recruiting | Washington University School of Medicine | 99 | 2026-11-30 | 2026-10-20 |
| Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Nonfunctional Neuroendocrine Neoplasms Somatostatin Analogue(s) - Neuroendocrine Neoplasm, Gastroenteropancreatic Neuroendocrine Neoplasm | Phase 3 | Not yet recruiting | Washington University School of Medicine | 240 | 2026-11-30 | 2026-10-19 |
| Low-Count Quantitative SPECT for Men Treated With Radium-223 Low-count quantitative single-photon emission computed tomography imaging - Prostate Cancer, Cancer of the Prostate | Not applicable | Recruiting | Washington University School of Medicine | 38 | 2026-11-01 | 2026-10-15 |
| Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced Cardiotoxicity 68Ga-Galmydar, PET/MRI, 18F-FDG - Lymphoma Cancer, Breast Cancer | Phase 1 | Not yet recruiting | Washington University School of Medicine | 36 | 2026-11-01 | 2026-09-24 |
| [18F]Fluorthanatrace - Positron Emission Tomography (FTT-PET) and ctDNA to Predict Response to PARP Inhibitor Therapy in Metastatic Prostate Cancer (mPC) 1-(4-(2-Fluoroethoxy)phenyl)-8,9-dihiydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one, FTT-PET/CT, EnhanceAR-Seq - Metastatic Prostate Cancer, Prostate Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 75 | 2026-11-01 | 2026-10-21 |
| Asciminib With or Without Sildenafil for Brain Tumors Asciminib, Sildenafil, Surgical resection or biopsy - Brain Tumor | Early Phase 1 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-10-31 | 2026-09-11 |
| CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma 64Cu-DOTA-ECL1i - Head and Neck Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M) | Phase 2 | Recruiting | Washington University School of Medicine | 90 | 2026-10-31 | 2026-10-07 |
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Obesity (98) · Breast Neoplasms (86) · Depression (57) · Diabetes Mellitus (50) · Neoplasms (47) · Leukemia, Myeloid, Acute (43) · Motor Activity (42) · Multiple Myeloma (40) · Pancreatic Neoplasms (37) · Parkinson Disease (36) · Diabetes Mellitus, Type 2 (31) · Carcinoma, Non-Small-Cell Lung (30) · Myelodysplastic Syndromes (30) · Cardiovascular Diseases (29) · Prostatic Neoplasms (28)
Blood Specimen Collection (30) · Exercise (22) · Standard of Care (22) · Fluorouracil (21) · Gemcitabine (20) · Cisplatin (19) · Granulocyte Colony-Stimulating Factor (19) · Radiotherapy (19) · pembrolizumab (19) · Carboplatin (18) · Nivolumab (17) · Cyclophosphamide (16) · Dexamethasone (16) · Cytarabine (15) · Filgrastim (15)
United States (1918) · Canada (52) · Malawi (26) · Nigeria (18) · Uganda (17) · Australia (12) · Ghana (12) · United Kingdom (12) · Sierra Leone (10) · Bangladesh (9) · Italy (9) · Spain (9) · France (8) · Germany (8) · Colombia (7)
Samuel Klein, MD (28) · Ravi Vij, M.D. (18) · Jay F Piccirillo, MD (17) · Mark J Manary, MD (15) · Mark Manary, MD (14) · Douglas Adkins, M.D. (12) · Simon Haroutounian, PhD (12) · Eric Lenze, MD (11) · Ramaswamy Govindan, M.D. (11) · Farrokh Dehdashti, M.D. (9) · Amanda Cashen, M.D. (8) · Daniel Morgensztern, M.D. (8) · Eric J Lenze, MD (8) · Jiayi Huang, M.D. (8) · Michael S Avidan, MBBCh (8)
PMID 31004409, PMID 33512717, PMID 34905513, PMID 37585253, PMID 38569683, PMID 42714910, PMID 12150647, PMID 15367925, PMID 17375138, PMID 18317237, PMID 18383112, PMID 18477783, PMID 19647838, PMID 19948045, PMID 20208057, PMID 20539253, PMID 21334602, PMID 21818149, PMID 22222548, PMID 22337229, PMID 22526637, PMID 22710617, PMID 23166334, PMID 23522057, PMID 23817024, PMID 24657120, PMID 24852500, PMID 24871971, PMID 25018070, PMID 25273286, PMID 25475435, PMID 25712598, PMID 25979608, PMID 26160288, PMID 26200928, PMID 26494483, PMID 26578308, PMID 27067170, PMID 28292947, PMID 28406662, PMID 28433500, PMID 28473464, PMID 28740827, PMID 28797458, PMID 29294006, PMID 29400693, PMID 29515037, PMID 29955682, PMID 30260448, PMID 30704863
P50CA171963 (7), UL1TR002345 (7), P50MH122351 (6), P30CA091842 (5), P50CA196510 (5), U01AG059798 (5), K12CA167540 (4), KL2TR002346 (4), R01AG046179 (4), U01AG042791 (4), R01AG053267 (3), R01DK088126 (3), R01ES033743 (3), R01HD085930 (3), R01HL144708 (3)