Intestinal Diseases: Clinical Trials

8100 completed, 3166 unknown, 2317 recruiting, 1373 terminated. 5242 Not applicable, 3757 Phase 2, 2212 Phase 1, 1643 Phase 3, 723 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	5242	Completed 2459, Unknown 1067, Recruiting 726, Not yet recruiting 319, Terminated 287, Active not recruiting 177, Withdrawn 125, Enrolling by invitation 62, Suspended 20
Phase 2	3757	Completed 1566, Unknown 596, Recruiting 524, Terminated 485, Active not recruiting 215, Not yet recruiting 178, Withdrawn 165, Suspended 19, Enrolling by invitation 9
Phase 1	2212	Completed 1049, Recruiting 323, Terminated 319, Unknown 208, Active not recruiting 130, Not yet recruiting 84, Withdrawn 82, Suspended 12, Enrolling by invitation 5
Phase 3	1643	Completed 817, Unknown 281, Recruiting 179, Terminated 167, Active not recruiting 101, Not yet recruiting 50, Withdrawn 41, Enrolling by invitation 4, Suspended 3
Phase 4	723	Completed 372, Unknown 127, Terminated 72, Recruiting 63, Not yet recruiting 38, Withdrawn 34, Active not recruiting 14, Enrolling by invitation 3
Early Phase 1	165	Completed 48, Unknown 37, Recruiting 23, Not yet recruiting 17, Terminated 14, Active not recruiting 10, Withdrawn 9, Enrolling by invitation 4, Suspended 3

Follow Intestinal Diseases: new trials by email Literature Review of Intestinal Diseases trials Research Report on Intestinal Diseases

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis	Phase 4	Not yet recruiting	Bausch Health Americas, Inc.	100	2029-06-01	2026-10-06
Bilio-pancreatic Complications of Congenital Duodenal Obstructions duodenal atresia - Duodenal Obstruction		Not yet recruiting	University Hospital, Angers	450	2028-12-01	2026-02-10
Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea	Not applicable	Not yet recruiting	Albert Einstein College of Medicine	8	2028-02-01	2026-10-13
The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp Shared Decision Making using a Patient Decision Aid. - Shared Decision Making, Colonic Polyp	Phase 2	Not yet recruiting	Vejle Hospital	110	2028-02-01	2026-04-30
ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	50	2028-01-01	2026-02-09
CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer CA102N, TAS-102, Bevacizumab - Metastatic Colorectal Cancer	Phase 2	Suspended	Holy Stone Healthcare Co., Ltd	100	2027-12-01	2026-09-18
Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer intravoxel incoherent motion magnetic resonance imaging - Rectal Neoplasms, Prognosis		Not yet recruiting	Sichuan Cancer Hospital and Research Institute	400	2027-11-01	2025-12-08
Liver Steatosis in Pediatric CD Patients Gluten-free diet - Celiac Disease in Children, Non-Alcoholic Fatty Liver Disease		Recruiting	University of Palermo	91	2027-11-01	2026-05-01
A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis)	Not applicable	Not yet recruiting	Nova Scotia Health Authority	70	2027-09-01	2026-09-08
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease Digital Mind Body Intervention mobile application - Crohn's Disease, Ulcerative Colitis	Not applicable	Not yet recruiting	Montefiore Medical Center	40	2027-07-01	2026-09-14
Analysis of the Role of the Microbiota in Diverticular Disease Diverticular Disease of Colon, Acute Diverticulitis		Not yet recruiting	Hospital of Navarra	285	2027-06-01	2026-09-02
Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission Adapted Physical Activity, Usual Care - Inflammatory Bowel Diseases (IBD), Fatigue	Not applicable	Not yet recruiting	University Hospital, Grenoble	120	2027-06-01	2026-09-11
SGA-OCRC: Prediction of 90-Day Major Adverse Postoperative Outcomes in Octogenarians With Resectable Colorectal Cancer Octogenarian Patients With Non-metastatic Resectable Colorectal Cancer		Not yet recruiting	Second Affiliated Hospital, Zhejiang University, School of Medicine	1000	2027-06-01	2026-10-29
Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial Balstilimab, Biopsy Procedure, Biospecimen Collection - Colorectal Adenocarcinoma, Stage II Colorectal Cancer AJCC v8	Phase 2	Recruiting	National Cancer Institute (NCI)	20	2027-05-25	2026-09-29
CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and Systemic Therapy for the Treatment of Colorectal Cancer Liver Metastases, CHAMP Trial Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver	Phase 1	Not yet recruiting	City of Hope Medical Center	36	2027-05-06	2026-09-25
PET/MRI in Rectal Cancer Total Neo-adjuvant Therapy, 18FDG-PET/MRI scan - Rectal Cancer	Phase 2	Not yet recruiting	AHS Cancer Control Alberta	40	2027-05-01	2026-10-28
Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis Piperacillin/Tazobactam, Ceftriaxone + Metronidazole - Appendicitis Perforated, Appendectomy, Laparoscopic	Phase 3	Not yet recruiting	McMaster Children's Hospital	180	2027-04-01	2026-10-09
ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch Surgery 5-ASA, Placebo - Ulcerative Colitis (UC), Pouchitis	Phase 4	Not yet recruiting	University Hospital, Linkoeping	110	2027-04-01	2026-08-19
Liver Transplantation for Non-Resectable Colorectal Liver Metastases Without Local Treatment Options Liver transplantation - Colorectal Neoplasms, Liver Neoplasms	Not applicable	Not yet recruiting	Charite University, Berlin, Germany	260	2027-04-01	2026-09-10
Cancer Awareness Among Syrian Migrants PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program - Breast Cancer Screening, Cervical Cancer Screening	Not applicable	Not yet recruiting	Toros University	30	2027-03-09	2026-10-15

Showing 20 of 17307. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (6131)  ·  Colonic Neoplasms (2382)  ·  Rectal Neoplasms (2242)  ·  Crohn Disease (1950)  ·  Colitis, Ulcerative (1798)  ·  Inflammatory Bowel Diseases (1550)  ·  Irritable Bowel Syndrome (998)  ·  Breast Neoplasms (811)  ·  Neoplasms (698)  ·  Pancreatic Neoplasms (654)  ·  Stomach Neoplasms (595)  ·  Carcinoma, Non-Small-Cell Lung (534)  ·  Neoplasm Metastasis (501)  ·  Lung Neoplasms (484)  ·  Ovarian Neoplasms (420)

Broader conditions

Digestive System Diseases (17187)  ·  Gastrointestinal Diseases (17100)  ·  Colonic Diseases (10805)  ·  Neoplasms by Site (9508)  ·  Digestive System Neoplasms (9455)  ·  Intestinal Neoplasms (9359)  ·  Gastrointestinal Neoplasms (9308)  ·  Neoplasms (8954)  ·  Rectal Diseases (8703)  ·  Gastroenteritis (4867)  ·  Pathological Conditions, Signs and Symptoms (3425)  ·  Colorectal Neoplasms (3235)  ·  Inflammatory Bowel Diseases (2269)  ·  Pathologic Processes (1998)

Interventions

Fluorouracil (671)  ·  Oxaliplatin (652)  ·  Bevacizumab (561)  ·  Leucovorin (547)  ·  Capecitabine (535)  ·  Irinotecan (490)  ·  Cetuximab (393)  ·  Radiotherapy (189)  ·  pembrolizumab (181)  ·  Folfox protocol (166)  ·  Colonoscopy (161)  ·  Infliximab (146)  ·  Panitumumab (137)  ·  Drug Therapy (135)  ·  Blood Specimen Collection (128)

Sponsors

National Cancer Institute (NCI) (222)  ·  Fudan University (148)  ·  Takeda (140)  ·  Sun Yat-sen University (132)  ·  M.D. Anderson Cancer Center (130)  ·  Assiut University (128)  ·  Pfizer (113)  ·  Sixth Affiliated Hospital, Sun Yat-sen University (113)  ·  Memorial Sloan Kettering Cancer Center (107)  ·  Assistance Publique - Hôpitaux de Paris (103)  ·  Mayo Clinic (102)  ·  Hoffmann-La Roche (100)  ·  AbbVie (94)  ·  AstraZeneca (84)  ·  Chinese University of Hong Kong (84)

Countries

United States (5472)  ·  China (2171)  ·  France (1524)  ·  Canada (1177)  ·  Italy (1170)  ·  United Kingdom (1128)  ·  Spain (1029)  ·  Germany (986)  ·  Belgium (757)  ·  Netherlands (753)  ·  South Korea (726)  ·  Denmark (596)  ·  Poland (586)  ·  Australia (566)  ·  Israel (535)

Top investigators

Norman Wolmark, MD (21)

Results publications

PMID 40243391, PMID 24275240, PMID 40357993, PMID 22825366, PMID 36306483, PMID 40013523, PMID 15496622, PMID 24533607, PMID 25430806, PMID 29380251, PMID 32445184, PMID 35588252, PMID 37162250, PMID 25625764, PMID 25694210, PMID 26893500, PMID 31268130, PMID 33356421, PMID 35648151, PMID 36124702, PMID 37368103, PMID 26049686, PMID 26187751, PMID 27144617, PMID 28712102, PMID 29850873, PMID 30476584, PMID 30679026, PMID 30739254, PMID 31077827, PMID 31378656, PMID 31599001, PMID 32816215, PMID 32816630, PMID 33538338, PMID 33684552, PMID 35792493, PMID 36342120, PMID 36526796, PMID 36931693, PMID 38425446, PMID 39778975, PMID 9146781, PMID 15933795, PMID 18316791, PMID 19269519, PMID 19339720, PMID 19735233, PMID 20195905, PMID 20526599

NIH funding

2023 (109), 2025 (82), 2017 (80), 2016 (68), 2019 (59), 2018 (56), 2015 (55), 2014 (45), 2009 (42), 2008 (32), P30CA033572 (32), P30CA015083 (26), P30CA014089 (22), P30CA016672 (18), P30CA068485 (15)