22106 completed, 8974 unknown, 5726 recruiting, 3418 terminated. 12650 Not applicable, 10694 Phase 2, 5929 Phase 1, 4510 Phase 3, 2464 Phase 4.
Follow Digestive System Diseases: new trials by email Literature Review of Digestive System Diseases trials Research Report on Digestive System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC certepetide, nab-paclitaxel, gemcitabine - Pancreas Cancer, Pancreatic Carcinoma | Phase 1 / Phase 2 | Withdrawn | Lisata Therapeutics, Inc. | 2030-01-01 | 2025-06-06 | |
| Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis High dose budesonide rectal foam, Low dose budesonide rectal foam, Matching placebo rectal foam - Ulcerative Colitis | Phase 4 | Not yet recruiting | Bausch Health Americas, Inc. | 100 | 2029-06-01 | 2026-10-06 |
| Bilio-pancreatic Complications of Congenital Duodenal Obstructions duodenal atresia - Duodenal Obstruction | Not yet recruiting | University Hospital, Angers | 450 | 2028-12-01 | 2026-02-10 | |
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Adaptive Neoadjuvant Therapy for Esophageal Cancer Neoadjuvant concurrent chemoradiotherapy - Esophageal Carcinoma, Neoadjuvant Therapy | Not applicable | Enrolling by invitation | Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center | 43 | 2028-03-01 | 2025-05-25 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp Shared Decision Making using a Patient Decision Aid. - Shared Decision Making, Colonic Polyp | Phase 2 | Not yet recruiting | Vejle Hospital | 110 | 2028-02-01 | 2026-04-30 |
| AI-Enabled Mobile App for Safe Eating in Older Adults With Dysphagia AI-Enabled Mobile Application plus Standard Care, Standard Dysphagia Education - Deglutition Disorders, Dysphagia | Not applicable | Not yet recruiting | KAM Chi Shan Anna | 332 | 2028-01-01 | 2026-09-23 |
| Methadone as an Alternative Treatment for Children Underdoing HSCT PCA plus methadone (Experimental), PCA Alone (SOC) - Leukemia, Aplastic Anemia | Phase 3 | Suspended | University of Texas Southwestern Medical Center | 60 | 2028-01-01 | 2025-10-23 |
| ACT for Veterans With IBD and Mental Health Challenges Acceptance and Commitment Therapy - Inflammatory Bowel Diseases, Crohn's Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 50 | 2028-01-01 | 2026-02-09 |
| National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patients - Phase-III Trial Umbilical cord Mesenchymal stem cell, Steroid, Standard Medical Treatment - Acute-On-Chronic Liver Failure | Phase 3 | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 100 | 2028-01-01 | 2025-08-17 |
| The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction Caloric Restriction, Hyperglycemic clamp - Type2diabetes | Phase 2 | Not yet recruiting | Adrian Vella | 20 | 2027-12-15 | 2026-10-28 |
| CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer CA102N, TAS-102, Bevacizumab - Metastatic Colorectal Cancer | Phase 2 | Suspended | Holy Stone Healthcare Co., Ltd | 100 | 2027-12-01 | 2026-09-18 |
| Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer intravoxel incoherent motion magnetic resonance imaging - Rectal Neoplasms, Prognosis | Not yet recruiting | Sichuan Cancer Hospital and Research Institute | 400 | 2027-11-01 | 2025-12-08 | |
| Liver Steatosis in Pediatric CD Patients Gluten-free diet - Celiac Disease in Children, Non-Alcoholic Fatty Liver Disease | Recruiting | University of Palermo | 91 | 2027-11-01 | 2026-05-01 | |
| Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas - Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor | Not applicable | Enrolling by invitation | Ohio State University Comprehensive Cancer Center | 12 | 2027-10-01 | 2026-10-13 |
| Oral Fosamprenavir for GERD Fosamprenavir Calcium 700 MG Oral Tablet, Placebo - Refractory Gastroesophageal Reflux Disease, Gastroesophageal Reflux Disease | Phase 2 | Not yet recruiting | Medical College of Wisconsin | 60 | 2027-10-01 | 2026-09-10 |
| DESIR. Evaluation of the Pre-therapeutic Activity of Dihydropyrimidine dEShydrogenase (DPD) in Patients With Cancer and/or Renal Failure blood sampling, Blood sampling - Renal Impairment, Digestive Cancers | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 742 | 2027-10-01 | 2026-11-02 | |
| Shuganhuazhuo Formula for Advanced Hepatocellular Carcinoma With Damp-Heat Syndrome Shuganhuazhuo Formula, Targeted therapy, Immunotherapy - HCC - Hepatocellular Carcinoma, Chinese Herbal Medicine | Phase 2 | Not yet recruiting | Xiang-Qian | 120 | 2027-09-01 | 2026-08-27 |
| A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis) | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 70 | 2027-09-01 | 2026-09-08 |
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