41 completed, 14 unknown, 10 recruiting, 6 withdrawn. 80 Phase 2, 14 Phase 1, 12 Phase 3.
Follow Surgery: new trials by email Literature Review of Surgery trials Research Report on Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II Study of Primary Tumor Resection and Selective Lymph Node Dissection Followed by RT for BTC With Lymph Node Metastases Primary Tumor Resection and Selective Lymph Node Dissection, Postoperative Radiotherapy, Capecitabine or S-1 - Biliary Tract Cancer (BTC), Surgery | Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 73 | 2026-10-08 | 2026-10-26 |
| Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery. PAI, PAI + steroid, PAI + zilretta - Knee Osteoarthritis, Musculoskeletal Disease | Phase 2 / Phase 3 | Recruiting | Walter Reed National Military Medical Center | 240 | 2026-09-01 | 2026-08-19 |
| Research on the Efficacy and Mechanism of Shouhui Tongbian Capsules in Treating Postoperative Constipation of Benign Anal and Rectal Diseases Based on Gut Microbiota Analysis Shouhui Tongbian Capsules, Lactulose Oral Solution Control Group - Intestinal Flora, Anorectal Diseases | Phase 1 / Phase 2 | Not yet recruiting | China-Japan Friendship Hospital | 120 | 2026-08-01 | 2026-07-22 |
| Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery FEIBA, FFP - Cardiac Disease, Surgery | Phase 2 | Recruiting | Northwell Health | 140 | 2025-11-03 | 2026-03-11 |
| A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery Bevonescein - Surgery, Nerve Injury | Phase 2 | Completed | Alume Biosciences, Inc. | 27 | 2024-10-16 | 2026-10-09 |
| Prevent Cardiac Surgery Associated AKI Trial CoQ10 1200 mg orally with Glutathione 1000 mg orally, Group B: Placebo CoQ10 orally and Placebo Glutathione orally - Renal Failure, Coronary Artery Disease | Phase 2 | Recruiting | George Washington University | 242 | 2024-07-18 | 2026-10-14 |
| Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer. ipilimumab, pembrolizumab, durvalumab, idarubicin, bevacizumab - Lung Cancer, Surgery | Phase 2 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 90 | 2024-07-01 | 2024-07-09 |
| Neoadjuvant Intra-tumor Double Immunotherapy for Hepatocellular Carcinoma. ipilimumab, pembrolizumab, durvalumab, idarubicin, bevacizumab - Hepatic Cancer, Surgery | Phase 2 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 90 | 2024-07-01 | 2024-07-09 |
| Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer Cardonilizumab, Chemoradiotherapy ±immunotherapy, Radical surgery - Esophageal Cancer, Immunotherapy | Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 60 | 2024-05-01 | 2025-05-30 |
| Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer Histamine Dihydrochloride (HDC), Interleukin-2 (IL-2) - Pancreatic Cancer, Surgery | Phase 2 | Not yet recruiting | Sahlgrenska University Hospital | 50 | 2024-04-01 | 2023-11-22 |
| Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC. Propranolol, Placebo - Pancreatic Cancer, Surgery | Phase 2 | Recruiting | Zealand University Hospital | 30 | 2024-03-20 | 2024-03-28 |
| Efficacy of Adapted Physical Activity on a Walking Platform in Elderly Patients HOspitalized for Cancer Surgery Early rehabilitation through Adapted Physical Activity - Oncology, Elderly Patients | Phase 2 | Recruiting | Centre Francois Baclesse | 60 | 2024-03-15 | 2026-01-12 |
| Tissue Inhibitor of Metalloproteinases 2 Level in Patients Undergoing Cardiac Surgery TIMP2 level - Acute Kidney Injury, Extracorporeal Circulation; Complications | Phase 1 / Phase 2 | Completed | Wuhan University | 100 | 2023-07-22 | 2025-03-12 |
| Comparative Analysis of the Lung Inflammatory Response After Thoracic Surgery With Single or Double Lung Ventilation: a Randomized, Pilot, Trial two lung ventilation, one lung ventilation - Thoracic Diseases, Surgery | Phase 2 | Completed | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | 40 | 2023-07-20 | 2024-05-08 |
| Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness FibCLOT, RiaSTAP - Hypofibrinogenemia, Surgical Blood Loss | Phase 2 | Completed | IRCCS Policlinico S. Donato | 40 | 2023-03-20 | 2024-02-28 |
| Induction Lorlatinib in Stage III Non-small Cell Lung Cancer Lorlatinib - Stage III NSCLC, Surgery | Phase 2 | Active not recruiting | Guangdong Provincial People's Hospital | 48 | 2023-03-15 | 2026-01-20 |
| Inhaled NO in Surgical Patients With Recent COVID-19 Infection Nitric Oxide Gas - Nitric Oxide, COVID-19 | Phase 2 | Completed | Xijing Hospital | 660 | 2023-02-17 | 2024-05-10 |
| Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery BX1000, Rocuronium Bromide - Neuromuscular Blockade, Anesthesia | Phase 2 | Completed | Baudax Bio | 80 | 2022-10-25 | 2023-08-01 |
| Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy Mitomycin, Lobaplatin - Colorectal Cancer, Chemotherapy Effect | Phase 2 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 201 | 2022-09-01 | 2022-02-21 |
| Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma Thyroxine - Thyroid Cancer, Surgery | Phase 2 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 140 | 2022-08-01 | 2023-10-17 |
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Hemorrhage (6) · Carcinoma, Non-Small-Cell Lung (4) · Lung Neoplasms (4) · Neoplasm Metastasis (4) · Neoplasms (4) · Pain (4) · Pain, Postoperative (4) · Pancreatic Neoplasms (4) · Stomach Neoplasms (4) · Blood Loss, Surgical (2) · Breast Neoplasms (2) · Esophageal Neoplasms (2) · Glioma (2) · Heart Diseases (2) · Intestinal Perforation (2)
Neoplasms (33) · Neoplasms by Site (31) · Pathological Conditions, Signs and Symptoms (29) · Pathologic Processes (22) · Digestive System Diseases (19) · Digestive System Neoplasms (15) · Gastrointestinal Diseases (12) · Signs and Symptoms (11) · Gastrointestinal Neoplasms (9) · Neurologic Manifestations (9) · Respiratory Tract Diseases (9) · Cardiovascular Diseases (7) · Endocrine Gland Neoplasms (7) · Endocrine System Diseases (7) · Neoplasms by Histologic Type (7)
Saline Solution (4) · Surgical Procedures, Operative (4) · Anti-Inflammatory Agents, Non-Steroidal (2) · Bevacizumab (2) · Bupivacaine (2) · Drug Therapy (2) · Idarubicin (2) · Ipilimumab (2) · Neoadjuvant Therapy (2) · Radiotherapy (2) · Standard of Care (2) · chlorhexidine gluconate (2) · durvalumab (2) · lobaplatin (2) · maltodextrin (2)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences (3) · Alume Biosciences, Inc. (2) · Medline Industries (2) · Second Affiliated Hospital of Guangzhou Medical University (2) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude (2) · Aalborg University Hospital (1) · Alexion Pharmaceuticals, Inc. (1) · BIRENDRA KUMAR SAH (1) · Baudax Bio (1) · Brugmann University Hospital (1) · Centre Francois Baclesse (1) · China-Japan Friendship Hospital (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Dana-Farber Cancer Institute (1)
United States (22) · China (16) · France (5) · Brazil (4) · Canada (4) · United Kingdom (4) · Belgium (2) · Denmark (2) · Germany (2) · Sweden (2) · Switzerland (2) · Taiwan (2) · Australia (1) · Austria (1) · Finland (1)
Kaixiong Tao, Professor (2) · Zhenfeng Zhang, MD, PhD (2) · Amy McCutchan, MD (1) · Andreas Muth (1) · Barbara C Brocki, PT (1) · Bashir M Hamid, MD (1) · Brandon C Chapman (1) · Brent Senior, MD (1) · Chong Lei, MD&phD (1) · Christopher Puccini, MD (1) · Claudia RF Andrade, Professor (1) · Dan L. Waitzberg, PhD (1) · Desheng Hu, Dr. (1) · Dirk Waldschmidt (1) · Dmitri Lissin, MD (1)
PMID 32306237, PMID 10091726, PMID 11813623, PMID 18306479, PMID 18779478, PMID 22189752, PMID 22282868, PMID 22287157, PMID 22510183, PMID 22831982, PMID 23095627, PMID 23361105, PMID 23398953, PMID 24837794, PMID 25532706, PMID 25680955, PMID 26310534, PMID 26489835, PMID 30203101, PMID 30234517, PMID 30340932, PMID 30850756, PMID 31155459, PMID 31255386, PMID 31388703, PMID 31516975, PMID 31806506, PMID 31815658, PMID 31839089, PMID 32045583, PMID 33086312, PMID 33278291, PMID 33279544, PMID 33482865, PMID 34176743, PMID 34996918, PMID 35123474, PMID 36408876, PMID 37071876, PMID 37314165, PMID 37877260, PMID 38282804, PMID 38380215, PMID 38485487, PMID 38876084, PMID 38919978, PMID 39002730, PMID 39383100, PMID 39499201, PMID 40595556
2014 (1), 2015 (1), 2018 (1), 2019 (1), P50CA165962 (1)