8 completed, 2 terminated, 1 enrolling by invitation, 1 recruiting. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 8, Terminated 2, Enrolling by invitation 1, Recruiting 1, Suspended 1, Unknown 1 |
Follow Spondylolysis: new trials by email Literature Review of Spondylolysis trials Research Report on Spondylolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Titanium vs. PEEK Fusion Devices in 1 Level TLIF Titanium Fusion Device, PEEK Fusion Device - Spine Fusion, Lumbar Spondylolisthesis | Phase 4 | Enrolling by invitation | Twin Cities Spine Center | 80 | 2024-09-01 | 2025-06-24 |
| Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion Caroxime sodium sulfonate, Desmopressin, 0.9% Sodium Chloride Injection - Lumbar Spondylolisthesis, Arthrosis; Spine | Phase 4 | Unknown | Chengdu University of Traditional Chinese Medicine | 126 | 2024-03-28 | 2024-03-15 |
| Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Completed | University Hospital Fattouma Bourguiba | 60 | 2023-01-01 | 2023-05-23 |
| Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery Ropivacaine Hydrochloride Injection, Sodium chloride - Spondylolisthesis, Lumbar Disc Herniation | Phase 4 | Completed | Ilse van de Wijgert | 76 | 2022-06-01 | 2024-04-17 |
| Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Recruiting | John O'Toole | 125 | 2022-02-01 | 2026-02-17 |
| Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Liposomal bupivacaine - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Suspended | Allina Health System | 60 | 2019-01-26 | 2024-12-11 |
| BIO4 Clinical Case Study: Cervical Spine 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System - Degenerative Disc Disease, Trauma (Including Fractures) | Phase 4 | Completed | Seton Healthcare Family | 20 | 2017-04-06 | 2022-01-14 |
| A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Exparel, Bupivacaine - Low Back Pain, Lumbosacral Radiculopathy | Phase 4 | Terminated | Virtua Health, Inc. | 19 | 2016-12-01 | 2021-01-06 |
| Effect of Pregabalin on Immediate Post-operative and Longterm Pain Pregabalin, Sugar pill, Oxycodone - Scoliosis, Spondylolisthesis | Phase 4 | Completed | Turku University Hospital | 64 | 2015-08-01 | 2020-10-19 |
| Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion teriparatide, Placebo - Lumbar Spondylosis, Lumbar Spondylolisthesis | Phase 4 | Completed | Shane Burch | 36 | 2011-08-01 | 2021-05-03 |
| Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Ketamine, Normal Saline - Idiopathic Scoliosis, Spondylolisthesis | Phase 4 | Completed | Julia Finkel | 54 | 2010-01-01 | 2016-01-14 |
| Spine Research With Roentgen Stereophotogrammetric Analysis Trabecular Metal Intervertebral Cage with RSA beads - Spondylolisthesis, Degenerative Lumbar Disc Disease | Phase 4 | Completed | Nova Scotia Health Authority | 17 | 2007-07-01 | 2013-02-20 |
| Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Lumbar Interbody Fusion - Low Back Pain, Spondylolisthesis | Phase 4 | Terminated | Medtronic Spinal and Biologics | 102 | 2004-10-01 | 2018-02-13 |
| Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented - Spondylolisthesis, Spinal Stenosis | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 304 | 2000-03-01 | 2015-08-04 |
Spondylolisthesis (14) · Spinal Stenosis (8) · Intervertebral Disc Displacement (7) · Intervertebral Disc Degeneration (3) · Low Back Pain (3) · Spondylosis (3) · Constriction, Pathologic (2) · Intervertebral disc disease (2) · Radiculopathy (2) · Scoliosis (2) · Congenital Abnormalities (1) · Hyperalgesia (1) · Neoplasms (1) · Osteoarthritis (1) · Pain, Postoperative (1)
Bone Diseases (14) · Musculoskeletal Diseases (14) · Spinal Diseases (13) · Spondylosis (11) · Pathological Conditions, Signs and Symptoms (9) · Pathological Conditions, Anatomical (8) · Hernia (7) · Neurologic Manifestations (5) · Signs and Symptoms (5) · Pain (4) · Back Pain (3) · Nervous System Diseases (3) · Neuromuscular Diseases (2) · Peripheral Nervous System Diseases (2)
Ropivacaine (2) · Saline Solution (2) · Sodium Chloride (2) · Bupivacaine (1) · Clonidine (1) · Deamino Arginine Vasopressin (1) · Dexamethasone (1) · Ketamine (1) · Laminectomy (1) · Oxycodone (1) · Parathyroid Hormone (1) · Pregabalin (1) · Single Person (1) · Sugars (1) · Teriparatide (1)
Allina Health System (1) · Chengdu University of Traditional Chinese Medicine (1) · Dartmouth-Hitchcock Medical Center (1) · Ilse van de Wijgert (1) · John O'Toole (1) · Julia Finkel (1) · Medtronic Spinal and Biologics (1) · Nova Scotia Health Authority (1) · Seton Healthcare Family (1) · Shane Burch (1) · Turku University Hospital (1) · Twin Cities Spine Center (1) · University Hospital Fattouma Bourguiba (1) · Virtua Health, Inc. (1)
United States (8) · Netherlands (2) · Canada (1) · Finland (1) · Germany (1) · Tunisia (1)
Carmen Li (1) · Christopher Alcala-Marquez, MD (1) · Dr. Wm Oxner, M.D. (1) · Eeric Truumees, MD (1) · Finkel C Julie, MD (1) · James N. Weinstein, DO, MS (1) · John O'Toole, MD (1) · Pestieau Sophie, MD (1) · Robert Greenleaf, MD (1) · Shane Burch, MD (1)
PMID 17538085, PMID 19487505, PMID 19755935, PMID 22048651, PMID 24809838, PMID 40601485
2015 (1), U01AR045444 (1)