136 completed, 44 recruiting, 37 withdrawn, 34 unknown. 208 Not applicable, 37 Phase 4, 19 Phase 3, 14 Phase 2, 8 Phase 1.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Mindfulness-based Stress Reduction Program for IBD Mindfulness based stress reduction, Active Control - Inflammatory Bowel Disease (Crohn&Amp;#39;s Disease and Ulcerative Colitis) | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 70 | 2027-09-01 | 2026-09-08 |
| Memantine Targeting Neurovascular Dysfunction After Mild and Moderate Traumatic Brain Injury (MEND) Memantine - Traumatic Brain Injury, Mild Traumatic Brain Injury | Phase 2 | Not yet recruiting | Nova Scotia Health Authority | 45 | 2027-06-01 | 2026-10-09 |
| Gender Affirming Mastectomy Analgesia Rial Paravertebral (single injection), Wide local infiltration - Gender Affirming Surgery, Mastectomy | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 64 | 2027-01-01 | 2026-10-06 |
| Starlight Therapy in Palliative Care Starlight Therapy - Symptom Management | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-12-15 | 2024-08-23 | |
| Continuous Erector Spinae Block for Analgesia Following Lumbar Decompression Continuous erector spinae plane block - Lumbar Spinal Stenosis, Lumbar Radiculopathy | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-12-01 | 2026-02-17 |
| Planned Operating-Room Extubation After Cardiac Surgery Planned Operating-Room Extubation, Standard Early ICU Extubation - Mechanical Ventilation, Cardiac Surgery | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 336 | 2026-11-01 | 2026-10-15 |
| Powered Impaction and Broaching in Elderly Total Hip Arthroplasty Total Hip Replacement with Automatic impaction and broaching device, Total Hip Replacement - Hip Arthroplasty Replacement, Gait Biomechanics | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-10-01 | 2026-08-05 |
| Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma Targeted Hyperthermia Therapy - Cutaneous Metastatic Melanoma | Not applicable | Not yet recruiting | Sona Nanotech Inc | 10 | 2026-10-01 | 2026-04-24 |
| GLP-1s in Hip and Knee Arthroplasty GLP-1 Receptor Agonists + Behavioral modification, Behavioral + placebo - Arthritis, Obesity & Overweight | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 100 | 2026-10-01 | 2026-08-10 |
| Mobile Application-Based Interventions for Cannabis Use in Young Adults With First Episode Psychosis CHAMPS, I Can Change - First Episode Psychosis (FEP), Psychosis | Not applicable | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 550 | 2026-09-15 | 2026-09-10 |
| Middle Ear Optical Coherence Tomography Imaging and Vibrometry in Patients With Hearing Loss OCT - clear - Conductive Hearing Loss, Sensorineural Hearing Loss | Not yet recruiting | Audioptics Medical Incorporated | 500 | 2026-08-01 | 2026-07-29 | |
| YOGA-FIT: Protocol for a Crossover Trial Investigating the Feasibility and Impact of Yoga for People With Stroke LoveYourBrain Yoga - Stroke | Not applicable | Recruiting | Nova Scotia Health Authority | 40 | 2026-08-01 | 2026-09-03 |
| Identifying Biomarkers of Response to Digital Interventions for Mood Disorders Online Cognitive Behavioural Therapy - Depression / Major Depressive Disorder, Bipolar Disorder (BD) | Not applicable | Enrolling by invitation | Centre for Addiction and Mental Health | 200 | 2026-07-28 | 2026-08-27 |
| Impact of Communication Delays on Anesthesia Response to Medical Emergencies and Ultrasound-Guided Regional Anesthesia Real-time communication, Delayed communication - Regional Anesthesia, Regional Anesthesia Morbidity | Not applicable | Recruiting | Nova Scotia Health Authority | 42 | 2026-07-11 | 2026-09-21 |
| Knee-hip Surgery Wait-list Support Program Support program - Knee Arthropathy, Hip Arthropathy | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 50 | 2026-06-15 | 2026-03-20 |
| Testing the Feasibility of a Virtual Application to Support Breast and Colorectal Cancer Survivors virtual self-management intervention - Breast Cancer Survivor, Colorectal Cancer Survivors | Not applicable | Recruiting | Nova Scotia Health Authority | 60 | 2026-04-20 | 2026-05-14 |
| Virtual Reality for Anxiety Management in Persons With Amyotrophic Lateral Sclerosis Virtual Reality Guided Breathing Exercise - ALS (Amyotrophic Lateral Sclerosis) | Not applicable | Not yet recruiting | Horizon Health Network | 60 | 2026-04-01 | 2026-03-16 |
| Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee Arthroplasty Mepivacaine Injection, Chloroprocaine Injection - Recovery Period, Anesthesia | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 170 | 2026-03-31 | 2026-02-06 |
| Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis Action-Based Cognitive Remediation - Psychosis, Alcohol Use Disorder | Not applicable | Recruiting | Nova Scotia Health Authority | 50 | 2026-03-27 | 2026-04-07 |
| Training Non-Anesthesia Personnel to Perform Nerve Blocks in Microgravity Simulated microgravity, Normal earth gravity - Nerve Block, Regional Anesthesia | Not applicable | Completed | Nova Scotia Health Authority | 30 | 2026-03-20 | 2026-09-30 |
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Depressive Disorder, Major (14) · Stroke (14) · Motor Activity (13) · Depression (11) · Psychotic Disorders (11) · Bipolar Disorder (9) · Neoplasms (9) · Feeding and Eating Disorders (8) · Breast Neoplasms (7) · Psychological Well-Being (7) · Frailty (6) · Osteoarthritis (6) · Pain, Postoperative (6) · Anxiety Disorders (5) · Atrial Fibrillation (5)
Exercise (6) · Therapeutics (6) · Cognitive Behavioral Therapy (5) · Cytidine Triphosphate (4) · Standard of Care (4) · Acetaminophen (3) · Lithium Carbonate (3) · Morphine (3) · Saline Solution (3) · aldesleukin (3) · Arthroplasty, Replacement, Hip (2) · Arthroplasty, Replacement, Knee (2) · Catheter Ablation (2) · Cognitive Training (2) · Dabigatran (2)
Canada (279) · United States (3) · Sweden (2) · Belgium (1) · Denmark (1) · France (1) · Germany (1) · Netherlands (1) · Poland (1) · South Korea (1) · Spain (1) · United Kingdom (1)
Rudolf Uher, MD, PhD (6) · Aaron Keshen, MD, FRCPC (5) · Ivan Wong, MD (4) · Ross K Leighton, MD, FRCS(C) (4) · Ivan H Wong, MD (3) · Lutz Weise, MD, PhD (3) · Philip G Tibbo, MD (3) · Scott Grandy, PhD (3) · David P Morris, MD (2) · Gail A Eskes, PhD (2) · Jai Shankar, MD (2) · John L Sapp, MD FRCPC (2) · Karim Mukhida, MD, PhD (2) · Lee Kirby, MD, FRCPC (2) · Ratika Parkash (2)
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