90 completed, 20 recruiting, 17 unknown, 14 not yet recruiting. 61 Not applicable, 28 Phase 1, 25 Phase 4, 23 Phase 2, 16 Phase 3.
Follow Single Person: new trials by email Literature Review of Single Person trials Research Report on Single Person
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain Syndrome Venlafaxine oral tablet combined with Education and Behavioral Modification Program (EBMP), Education and Behavioral Modification Program (EBMP) only - Bladder Pain Syndrome, Chronic Pelvic Nociplastic Pain | Phase 1 | Not yet recruiting | Beijing Tiantan Hospital | 140 | 2026-12-31 | 2026-07-13 |
| A Study to Learn the Safety and Efficacy of HLX37 in Combination With Chemotherapy for First-line Treatment in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Investigational drug: HLX37 dose1, IV, Q3W, PEMBROLIZUMAB (alone or when added to a regimen above), Carboplatin (Investigator discretion) - NSCLC (Advanced Non-small Cell Lung Cancer) | Phase 2 / Phase 3 | Not yet recruiting | Shanghai Henlius Biotech | 1438 | 2026-11-30 | 2026-10-08 |
| Study of Peripheral Neuropathy in Patients With Advanced Urothelial Cancer Treated With Enfortumab Vedotin and Pembrolizumab With Supportive Neuridase (ENDEAVOR) enfortumab vedotin (EV), PEMBROLIZUMAB (alone or when added to a regimen above), Neuridase - Urothelial Carcinoma (UC), Peripheral Nerve Disease | Not applicable | Not yet recruiting | University of Florence | 40 | 2026-09-01 | 2026-06-08 |
| Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only - PTSD, Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Not yet recruiting | Leslie Lundahl | 280 | 2026-09-01 | 2026-08-26 |
| Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty Adductor Canal Block (ACB) Only - Arthroplasty, Replacement, Knee, Nerve Block Assessment | Recruiting | Konya City Hospital | 623 | 2026-08-09 | 2026-08-12 | |
| Oral Tranexamic Acid Plus Triple Combination vs Triple Combination Alone in Melasma Oral tranexamic acid + triple combination cream (fluocinolone acetonide + hydroquinone + tretinoin), Triple combination cream (fluocinolone acetonide + hydroquinone + tretinoin) alone - Melasma, Melasma (Facial Melasma) | Phase 4 | Not yet recruiting | Combined Military Hospital Abbottabad | 128 | 2026-07-15 | 2026-07-28 |
| Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients. Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only - Nerve Block/Methods | Phase 2 / Phase 3 | Recruiting | Children's Cancer Hospital Egypt 57357 | 126 | 2026-07-09 | 2026-09-01 |
| Strain Counter Strain With and Without Sustained Natural Aphophyseal Glide in Non Specific Neck Pain Strain Counterstrain + SNAG with Common Treatment, Strain Counterstain (SCS) only - Cervical Pain | Not applicable | Recruiting | Riphah International University | 68 | 2026-06-20 | 2026-07-24 |
| Reperfusion Approach in Predicted In-hospital Delay for Primary PCI in STEMI Single, weight-adjusted i.v. bolus of tenecteplase, catheterisation - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Not yet recruiting | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | 240 | 2026-05-20 | 2026-06-11 |
| Effectiveness of Combined Kinesiotapping and Core Stability Exercises in SIJ Dysfunction Kinesiotapping and Core Stability Exercises, Core Stability Exercises (CSE) only - Sacroiliac Dysfunction | Not applicable | Completed | Riphah International University | 44 | 2026-03-26 | 2026-08-26 |
| Effectiveness of Epigallocatechin-3-Gallate (Green Tea Extract) as Adjunctive Locally Delivered Nanotherapeutic in the Treatment of Stage II Periodontitis Ten patients with stage II periodontitis will receive epigallocatechin-3-gallate (EGCG)-loaded chitosan nanoparticulate gel injected into the periodontal pockets, chitosan nanoparticulate gel (CTN gel), scaling and root planing (SRP) only. - Peridontitis | Phase 1 | Recruiting | Mansoura University | 30 | 2026-03-16 | 2026-08-10 |
| Effect of Adding Vastus Medialis Nerve Block to Adductor Canal Block After Anterior Cruciate Ligament Reconstruction Adductor Canal Block (ACB) Only, Vastus Medialis Nerve Block - Anterior Cruciate Ligament Injury | Not applicable | Completed | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 104 | 2026-03-14 | 2026-07-14 |
| Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers To determine the efficacy of a gel containing polyhexanide and biguanide, alone or in combination with alginate with or without silver, in preventing biofilm in PU, in terms of healing at 4 weeks - Pressure Ulcers, Pressure Ulcers Stage III | Early Phase 1 | Not yet recruiting | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | 140 | 2026-01-30 | 2026-02-10 |
| A Phase 3 Study of [177Lu]Ludotadipep for Metastatic Castration-Resistant Prostate Cancer [177-Lu]Ludotadipep, Best supportive care/standard of care (BSC/SOC) alone - Prostate Cancer, mCRPC | Phase 3 | Recruiting | FutureChem | 114 | 2026-01-26 | 2026-10-01 |
| Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty Adductor Canal Block (ACB) Only, IPACK block, BiFeS Block - Knee Osteoarthritis, Postoperative Pain Management | Not applicable | Completed | Ataturk University | 74 | 2025-12-01 | 2026-10-05 |
| Comparison of ACB With ACB and BiFeS Combination in Knee Arthroplasty Surgeries Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + Biceps Femoris Short Head Block (BiFeS) - Postoperative Pain Management, Knee Surgery | Not applicable | Not yet recruiting | Cumhuriyet University | 60 | 2025-11-20 | 2025-11-25 |
| Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Plus Biceps Femoris Short Head Block in Patients Undergoing Knee Arthroscopy Adductor Canal Block (ACB) Only, biceps femoris short head block + Adductor Canal Block (ACB) - Postoperative Pain Management | Not applicable | Completed | Kanuni Sultan Suleyman Training and Research Hospital | 50 | 2025-11-20 | 2026-04-07 |
| Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries Adductor Canal Block (ACB) Only - Postoperative Analgesia, Morphine and Dexmedetomidine | Phase 1 / Phase 2 | Not yet recruiting | Kafrelsheikh University | 15 | 2025-11-17 | 2025-11-20 |
| Perioperative Chemotherapy and Immunotherapy for Locally Recurrent Nasopharyngeal Carcinoma Gemcitabine (GEM), Cisplatin, PEMBROLIZUMAB (alone or when added to a regimen above) - Nasopharyngeal Cancer Recurrent, Nasopharyngeal Cancinoma (NPC) | Phase 2 | Not yet recruiting | The University of Hong Kong | 53 | 2025-11-01 | 2025-09-04 |
| NMES With PNF for Ankle Sprain Rehabilitation Proprioceptive neuromuscular facilitation (PNF) with neuromuscular electrical stimulation (NMES), Proprioceptive neuromuscular facilitation (PNF) only - Ankle Sprain | Not applicable | Recruiting | Fooyin University | 60 | 2025-10-01 | 2025-11-17 |
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Carcinoma, Non-Small-Cell Lung (8) · COVID-19 (6) · Asthma (5) · Pain (4) · Depression (3) · Infertility (3) · Neoplasms (3) · Obesity (3) · Pain, Postoperative (3) · Prostatic Neoplasms (3) · Psychological Well-Being (3) · Vitamin D Deficiency (3) · Acute Coronary Syndrome (2) · Anterior Cruciate Ligament Injuries (2) · Anxiety Disorders (2)
Merck KGaA, Darmstadt, Germany (6) · Longbio Pharma (4) · Kaleido Biosciences (3) · Mansoura University (3) · Ain Shams University (2) · AstraZeneca (2) · CHU de Reims (2) · Columbia University (2) · Elsan (2) · GlaxoSmithKline (2) · Guangzhou Jiayin Biotech Ltd (2) · Johns Hopkins University (2) · Riphah International University (2) · Shandong University (2) · AM-Pharma (1)
United States (47) · China (14) · France (10) · Turkey (Türkiye) (9) · Canada (8) · Egypt (8) · Italy (8) · Australia (7) · Russia (7) · Germany (6) · United Kingdom (6) · Israel (5) · Spain (5) · Netherlands (4) · Poland (4)
Mark Wingertzahn, PhD (3) · Abduallah S Ali (1) · Abdullah S Ali, Programme Manager (1) · Alexandru Crisan, Phd (1) · Ali Amar, MBBS, FCPS, CHPE (1) · Amna Zia, PhD* (1) · Andreas Martensson (1) · Andrew Ostor (1) · Annelies Legters (1)
PMID 34870327, PMID 16170175, PMID 18427231, PMID 20457669, PMID 21071331, PMID 21744082, PMID 21793744, PMID 21982342, PMID 22342863, PMID 23207787, PMID 23357165, PMID 23786930, PMID 24331154, PMID 24498872, PMID 24770617, PMID 24932181, PMID 24976972, PMID 25271011, PMID 25318563, PMID 25483677, PMID 25722382, PMID 25867990, PMID 25894148, PMID 26730981, PMID 26809431, PMID 27159009, PMID 27220317, PMID 27468073, PMID 27529314, PMID 28196163, PMID 28441975, PMID 28493599, PMID 28887751, PMID 29338855, PMID 30065909, PMID 30117635, PMID 30461121, PMID 30466850, PMID 30526588, PMID 31594857, PMID 31833543, PMID 32543118, PMID 32590151, PMID 32694032, PMID 33383226, PMID 33810796, PMID 33992421, PMID 34397042, PMID 34444304, PMID 34585740
2016 (1), 2019 (1), 2023 (1), DP3DK101055 (1), P50MH115838 (1), R01AI145675 (1), R01DK067561 (1), R01DK112136 (1), R01MH128913 (1), R01NS097876 (1)