30 completed, 11 unknown, 7 recruiting, 4 withdrawn. 26 Not applicable, 6 Phase 2, 5 Phase 4, 4 Phase 3, 3 Phase 1.
Follow Intervertebral disc disease: new trials by email Literature Review of Intervertebral disc disease trials Research Report on Intervertebral disc disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy Mirror Image Spine Correction Exercises, Conservative Physiotherapy - Radiculopathy, Radiculopathy Lumbar | Not applicable | Not yet recruiting | University of Sharjah | 64 | 2026-09-01 | 2026-04-30 |
| The Effect of NSAID on Serum Periostin Intervertebral Disc Disease | Recruiting | Keimyung University Dongsan Medical Center | 144 | 2026-06-22 | 2026-08-18 | |
| Relationship of Periostin and ODI, EQ-5D Blood sampling for ELISA - Intervertebral Disc Disease | Recruiting | Keimyung University Dongsan Medical Center | 53 | 2026-06-22 | 2026-08-18 | |
| Clinical and MRI Findings in Lumbar Disc Disease Lumbar Disc Disease, Low Back Pain | Not yet recruiting | Assiut University | 96 | 2026-04-01 | 2026-04-08 | |
| Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain Fluoroscopy-guided lumbar transforaminal epidural steroid injection - Lumbar Disc Disease, Radiculopathy Lumbar | Not yet recruiting | Mersin University | 120 | 2026-04-01 | 2026-03-27 | |
| AuriculoTherapy NeuroImaging Cryo-auriculotherapy, Sham auriculotherapy, Experimental auricular stimulation - Low Back Pain, Chronic Low-back Pain | Not applicable | Recruiting | Keith M Vogt | 60 | 2025-07-30 | 2026-02-18 |
| The Effect of Menthol Ice and Frozen Saline Applications After Lumbar Disc Surgery Menthol ice, Frozen saline, No Interventions - Thirst, Sore Throat | Not applicable | Completed | Istanbul University - Cerrahpasa | 102 | 2025-04-15 | 2025-12-15 |
| Development of a Fascial Training Based Mobile Application and Investigation of Its Effectiveness in Patients With Disc Herniation fascial exercise home brochure, Fascial exercise based mobile application, lumbal stabilizasyon home brochure - Lumbar Disc Disease, Lumbal Disc Herniation | Not applicable | Enrolling by invitation | Baskent University | 1 | 2025-02-01 | 2025-09-23 |
| Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections Ultrasound microendoscopic technique, Fluoroscopy - Radiculopathy Lumbar, Disc Disease Lumbar | Not applicable | Unknown | American University of Beirut Medical Center | 124 | 2024-12-01 | 2024-06-21 |
| LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF) LDGraft, Allograft Bone - Degenerative Disc Disease, Lumbar Disc Disease | Phase 1 / Phase 2 | Recruiting | Locate Bio Pty Ltd | 40 | 2024-11-12 | 2026-08-26 |
| RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain Discogenic Low Back Pain, Intervertebral Disc Degeneration | Enrolling by invitation | EPC Education s.r.o. | 120 | 2024-10-01 | 2026-01-14 | |
| PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study Spinoplasty with Platelet Rich Plasma - Lower Back Pain Chronic, Lumbar Disc Disease | Phase 2 | Completed | Allmed Medical Center | 35 | 2024-09-15 | 2025-12-08 |
| A Clinical Trial to Evaluate the Safety and Efficacy of Single-use Fibrous Ring Sutures for the Suture of Fibrous Ring Incision After Nucleus Pulposus Removal Disposable fibrous ring sutures - Intervertebral Disc Disorder | Not applicable | Unknown | Suzhou Care-Real Medical Technology Co., Ltd. | 135 | 2024-08-15 | 2024-07-19 |
| The Effect of Mediclore as an Anti-adhesion Agent and Safety in Full-endoscopic Spine Surgery: a Preliminary Study Mediclore, Normal Saline - Lumbar Disc Disease, Epidural Fibrosis | Phase 4 | Unknown | King Chulalongkorn Memorial Hospital | 78 | 2023-10-01 | 2023-09-14 |
| NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study NOCISCAN-LS Disc MR Spectroscopy - Lumbar Disc Disease | Unknown | Nocimed, LLC | 240 | 2023-04-01 | 2022-07-29 | |
| Effects of Kinesio Taping on Pain, Endurance, Proprioception, Mobility and Disability in Lumbar Disc Herniation Routine Treatment + I Taping, Routine Treatment + Star Taping, Routine Treatment - Lumbar Disc Herniation, Lumbar Disc Disease | Not applicable | Completed | Sevtap Günay | 90 | 2023-03-15 | 2025-01-15 |
| Determinants of Clinical Outcome After Caudal Epidural Adhesiolysis for Chronic Lumbar Radicular Pain Radicular Pain, Adhesiolysis | Active not recruiting | Mersin University | 40 | 2023-01-01 | 2026-03-23 | |
| Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain Physical Therapy - Low Back Pain, Lumbar Disc Disease | Completed | Afyonkarahisar Health Sciences University | 160 | 2022-12-15 | 2023-02-01 | |
| A Post Market Surveillance on INFUSE Bone Graft INFUSE™ Bone Graft - Intervertebral Disc Degeneration, Spinal Fusion | Recruiting | Medtronic Spinal and Biologics | 600 | 2022-08-10 | 2025-03-20 | |
| Ultrasound-Guided vs. Surgeon-Performed (Free-hand) Erector Spinae Plane Block US-guided ESPB., Surgeon-performed (Free-hand) ESPB. - Lumbar Disc Herniation, Lumbar Disc Disease | Not applicable | Completed | Medipol University | 102 | 2022-08-01 | 2026-03-10 |
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Intervertebral Disc Degeneration (16) · Intervertebral Disc Displacement (13) · Spinal Stenosis (12) · Radiculopathy (11) · Low Back Pain (9) · Spondylolisthesis (7) · Sciatica (5) · Spondylosis (4) · Spinal Diseases (3) · Chronic Pain (2) · Hypertension (2) · Pain, Postoperative (2) · Alopecia (1) · Alzheimer Disease (1)
Bone Diseases (33) · Musculoskeletal Diseases (32) · Spinal Diseases (30) · Pathological Conditions, Signs and Symptoms (27) · Neurologic Manifestations (19) · Signs and Symptoms (19) · Pain (18) · Nervous System Diseases (16) · Neuromuscular Diseases (15) · Peripheral Nervous System Diseases (15) · Pathological Conditions, Anatomical (14) · Hernia (13) · Back Pain (9) · Pathologic Processes (7) · Spondylolysis (7)
Acetaminophen (2) · Ropivacaine (2) · Saline Solution (2) · Sodium Chloride (2) · Total Disc Replacement (2) · Acupuncture Therapy (1) · Anesthetics, General (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Control Groups (1) · Dipyrone (1) · Enzyme-Linked Immunosorbent Assay (1) · Genes, mos (1) · Glucose (1) · Ibuprofen (1)
Cantonal Hospital of St. Gallen (2) · GCS Ramsay Santé pour l'Enseignement et la Recherche (2) · Hospital for Special Surgery, New York (2) · Keimyung University Dongsan Medical Center (2) · Medipol University (2) · Mersin University (2) · NuTech Medical, Inc (2) · Red de Terapia Celular (2) · Seikagaku Corporation (2) · University of Valencia (2) · Afyonkarahisar Health Sciences University (1) · Ain Shams University (1) · Akdeniz University (1) · Allina Health System (1) · Allmed Medical Center (1)
United States (21) · Turkey (Türkiye) (12) · South Korea (5) · Spain (5) · France (4) · Lebanon (2) · Switzerland (2) · Australia (1) · Egypt (1) · Germany (1) · Italy (1) · Mexico (1) · Netherlands (1) · Palestinian Territories (1) · Poland (1)
Nicolai Maldaner, MD (2) · Ana Sanchez, MD, PhD (1) · Bong-Soon Chang, MD, PhD (1) · Byung-Joon Shin, MD, PhD (1) · Catherine Himo Gang (1) · Chambliss Harrod, MD (1) · Chong-Suh Lee, MD, PhD (1) · Christian Cerecedo, MD (1) · Christopher Alcala-Marquez, MD (1) · Daniel Rhon, DPT, DSc (1) · David C Noriega, MD, PhD (1) · Domagoj Coric, MD (1) · Eduardo Galvan Hernandez, MD (1)
PMID 10214567, PMID 15950689, PMID 18164459, PMID 20542472, PMID 25032676, PMID 25203751, PMID 25293819, PMID 27646404, PMID 27661661, PMID 27848245, PMID 29723636, PMID 30100096, PMID 30217693, PMID 30795797, PMID 31042663, PMID 31444917, PMID 32708699, PMID 32779775, PMID 33974372, PMID 34033596, PMID 34042414, PMID 34352935, PMID 35015137, PMID 35800997, PMID 36998982, PMID 37038216, PMID 37182704, PMID 37410465, PMID 39842027, PMID 40601485, PMID 41511609