141 completed, 57 unknown, 37 recruiting, 37 terminated. 180 Not applicable, 16 Phase 4, 13 Phase 2, 11 Phase 1, 9 Phase 3.
Follow Spondylosis: new trials by email Literature Review of Spondylosis trials Research Report on Spondylosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Study of ProteiOS in Lumbar Interbody Fusion (TLIF) Allograft-derived growth factor (ProteiOS®), Standard of Care (SOC) - Degenerative Disc Disease, Spinal Stenosis Lumbar | Not applicable | Not yet recruiting | Isto Biologics | 280 | 2026-12-01 | 2026-08-20 |
| Kore Fiber PLF Study Kore Fiber, Autologous bone graft - Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease | Not applicable | Not yet recruiting | Kolosis Bio, LLC | 75 | 2026-11-01 | 2026-10-22 |
| Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials Sensitization Acupuncture, Traditional Acupuncture - Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis | Not applicable | Not yet recruiting | Jiangxi University of Traditional Chinese Medicine | 30 | 2026-10-10 | 2026-10-09 |
| The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance Pneumothorax, Intestinal Obstruction | Not yet recruiting | The Third Affiliated Hospital of Southern Medical University | 500 | 2026-10-01 | 2026-10-15 | |
| Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover Ready Set Recover - Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons | Early Phase 1 | Not yet recruiting | National University of Natural Medicine | 60 | 2026-09-30 | 2026-08-17 |
| Comparative Effectiveness of Two Different Approaches to Radiofrequency Ablation of Lumbar Medial Branch Nerves Radiofrequency ablation of lumbar medial branch nerves. - Lumbar Spondylosis | Not applicable | Not yet recruiting | Milton S. Hershey Medical Center | 25 | 2026-08-01 | 2026-07-23 |
| Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis. Group A: Clinical Based Rehabilitation, Group B: Synchronized Telerehabilitation - Grade-II Cervical Spondylosis | Not applicable | Not yet recruiting | Lahore University of Biological and Applied Sciences | 52 | 2026-07-01 | 2026-07-01 |
| Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain Chronic Pain, PERIPHERAL NEUROPATHY | Recruiting | Yale University | 80 | 2026-06-20 | 2026-08-21 | |
| Hard Cervical Collar Use Following Posterior Cervical Fusion Hard Cervical Collar - Spinal Stenosis Cervical, Radiculopathy, Cervical Region | Not applicable | Recruiting | Georgetown University | 150 | 2026-06-03 | 2026-10-01 |
| Effectiveness of Pressure Biofeedback-Assisted Deep Cervical Flexor Training With and Without Scapular Stabilization Exercises on Pain, Range of Motion and Neck Disability in Cervical Spondylosis Pressure Biofeedback-Assisted Deep Cervical Flexor Training, Scapular Stabilization Exercises, Standard Physiotherapy - Cervical Spondylosis | Not applicable | Recruiting | Ibadat International University, Islamabad | 44 | 2026-06-03 | 2026-09-28 |
| High-Frequency Electroacupuncture at Cervical Huatuo Jiaji Points Combined With Electromagnetic Field Therapy for Cervical Spondylotic Radiculopathy High-Frequency Electroacupuncture at Cervical Huatuo Jiaji (EX-B2), Pulsed Electromagnetic Field Therapy, Conventional High-Frequency Electroacupuncture - Cervical Spondylosis, Neck Pain | Not applicable | Recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 104 | 2026-06-02 | 2026-07-31 |
| Efficacy of Three-Needle Dazhui and Electroacupuncture for Cervical Spondylosis With Wind-Cold Syndrome Standard Electroacupuncture, Three-Needle Dazhui Technique & Electroacupuncture, Standard Care Drugs - Cervical Spondylosis, Wind-Cold Syndrome | Not applicable | Recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 74 | 2026-06-01 | 2026-07-20 |
| Validity of the Turkish Translation of the Modified JOA Spondylosis, Cervical, Spinal Cord Compression | Recruiting | Izmir Democracy University | 70 | 2026-05-10 | 2026-05-13 | |
| Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury EC5026 oral tablet, Placebo oral tablet - Spinal Cord Injuries, Neuropathic Pain | Phase 1 | Recruiting | EicOsis Human Health Inc. | 36 | 2026-05-01 | 2026-07-10 |
| A Pilot Study on the Safety of Active Conservative Management of Low Grade Lumbar Stress Reactions in Adolescent Soccer Players Active rehabilitation protocol - Spondylolysis Lumbar | Not applicable | Not yet recruiting | Western Norway University of Applied Sciences | 40 | 2026-05-01 | 2026-05-06 |
| PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System - Degenerative Disc Disease (DDD), Spinal Stenosis | Recruiting | Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co. | 561 | 2026-04-27 | 2026-05-29 | |
| Effect of Hip Extension Mobilization on Functional Disability in Patients With Spondylolisthesis hip extension mobilization, conventional treatment - Spondylolisthesis | Not applicable | Not yet recruiting | Cairo University | 32 | 2026-04-25 | 2026-04-23 |
| Comparative Effects of Gong's Mobilization and Maitland Mobilization in Patients With Cervical Spondylosis Gong's Mobilization, Maitland Cervical Mobilization - Cervical Spondylosis, Neck Pain | Not applicable | Completed | University of Faisalabad | 50 | 2026-04-24 | 2026-09-08 |
| Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain. Electroacupuncture, Auricular Acupressure, Sham Auricular Acupressure - Chronic Low Back Pain (CLBP), Lumbar Spondylosis | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 76 | 2026-04-20 | 2026-08-14 |
| Proprio Spine Measurement Tool Intraoperative spinal measurement system - Intervertebral Disc Degeneration, Intervertebral Disc Displacement | Not applicable | Withdrawn | Duke University | 2026-04-20 | 2026-04-23 |
Showing 20 of 320. Sign in to see all of them.
Spondylolisthesis (205) · Spinal Stenosis (92) · Intervertebral Disc Degeneration (86) · Intervertebral Disc Displacement (35) · Low Back Pain (30) · Radiculopathy (24) · Constriction, Pathologic (16) · Spondylolysis (14) · Scoliosis (12) · Neck Pain (11) · Spinal Diseases (9) · Intervertebral disc disease (8) · Lymphoma, Follicular (8) · Pain (7)
Bone Diseases (319) · Musculoskeletal Diseases (319) · Spinal Diseases (311) · Spondylolysis (199) · Pathological Conditions, Signs and Symptoms (116) · Signs and Symptoms (74) · Neurologic Manifestations (72) · Pain (59) · Pathological Conditions, Anatomical (52) · Nervous System Diseases (51) · Hernia (35) · Back Pain (31) · Neuromuscular Diseases (29) · Peripheral Nervous System Diseases (28)
Electroacupuncture (7) · Gene Fusion (7) · Sodium Chloride (5) · Transplantation, Autologous (5) · Laminectomy (4) · Saline Solution (4) · Spinal Fusion (4) · Acetaminophen (3) · Cupping Therapy (3) · Physical Therapy Modalities (3) · Ropivacaine (3) · Standard of Care (3) · Surgical Procedures, Operative (3) · Analgesia, Patient-Controlled (2) · Chewing Gum (2)
Zimmer Biomet (7) · Riphah International University (6) · Cairo University (5) · NuVasive (5) · Ohio State University (5) · University of Medicine and Pharmacy at Ho Chi Minh City (5) · Aesculap AG (4) · Baxano Surgical, Inc. (4) · K2M, Inc. (4) · Nationwide Children's Hospital (4) · SeaSpine, Inc. (4) · Allina Health System (3) · Assiut University (3) · Dartmouth-Hitchcock Medical Center (3) · Duke University (3)
United States (141) · China (22) · Germany (13) · Canada (12) · France (12) · Pakistan (12) · Netherlands (11) · Italy (8) · South Korea (7) · Turkey (Türkiye) (7) · Vietnam (7) · Egypt (6) · Spain (6) · Switzerland (6) · Norway (4)
Kyle Malone, MS (4) · Aaron Bernstein, PhD (2) · Donna Skerrett, MD (2) · Doron Dinstein, MD (2) · Jan Siewe, Dr. (2) · Joel Batts (2) · Kern Singh, MD (2) · Mitchell Selhorst, DPT (2) · Neha Sharma, PhD (2) · Wilson Z Ray, MD (2) · Zoher Ghogawala, MD (2) · Abdul Ghafoor Sajjad, Phd* (1) · Adam M Pearson, MD (1)
PMID 27825292, PMID 10360702, PMID 10488513, PMID 11172169, PMID 11180753, PMID 11723406, PMID 12709856, PMID 13287061, PMID 15541695, PMID 16227895, PMID 17256032, PMID 17538085, PMID 17906571, PMID 19125304, PMID 19342933, PMID 19487505, PMID 19574662, PMID 19752698, PMID 19755935, PMID 20121352, PMID 20375829, PMID 21235299, PMID 21372654, PMID 21471834, PMID 21492571, PMID 21824580, PMID 22008088, PMID 22048651, PMID 22155226, PMID 22772577, PMID 22817607, PMID 22958075, PMID 23373567, PMID 23386279, PMID 23442780, PMID 23448898, PMID 23526904, PMID 23591658, PMID 23783372, PMID 23948848, PMID 23962994, PMID 23962996, PMID 23962998, PMID 23962999, PMID 23963001, PMID 23963004, PMID 23963009, PMID 23981820, PMID 24005994, PMID 24026148
2015 (1), 2016 (1), K23AR077088 (1), K24AR080786 (1), U01AR045444 (1)