277 completed, 124 unknown, 79 recruiting, 46 not yet recruiting. 604 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 604 | Completed 277, Unknown 124, Recruiting 79, Not yet recruiting 46, Terminated 44, Withdrawn 16, Active not recruiting 8, Enrolling by invitation 5, Suspended 5 |
Follow Shock: new trials by email Literature Review of Shock trials Research Report on Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prehospital mSOFA-Kit Decision Support for the Detection of Multiple Organ Failure mSOFA-Kit, Standard XABCDE assessment - Multiple Organ Failure, Critical Illness | Not applicable | Not yet recruiting | University of Valladolid | 3780 | 2027-04-01 | 2026-11-10 |
| Biological Effects of Hemoadsorption in Septic Shock Hemoadsorption cartridge - Septic Shock, Vasopressor Resistance, Multiple Organ Dysfunction | Not applicable | Not yet recruiting | Miguel Sanchez Garcia | 16 | 2027-01-07 | 2026-07-20 |
| Remote Ischemic Postconditioning in Septic Shock Remote ischemic conditioning, No intervention - Adult Patients With Septic Shock Admitted in Intensive Care Unit | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 720 | 2027-01-01 | 2026-10-09 |
| Vitamin C for Acute Kidney Injury in ACLF With Septic Shock: A Randomized Controlled Trial Vitamin C, Standard of Care (SOC) - Acute-on-Chronic Liver Failure (ACLF) | Not applicable | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 110 | 2026-12-15 | 2026-11-06 |
| Wearable Core Body Temperature Monitoring for Early Detection of Cytokine Release Syndrome in Outpatients Receiving CAR T-Cell Therapy TempShield Continuous Temperature Monitoring, Standard of Care - Myeloma | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 105 | 2026-12-01 | 2026-11-05 |
| ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers ICU-SUCCEED, Augmented Usual Care - Acute Respiratory Failure, Critical Illness | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 144 | 2026-11-15 | 2026-11-05 |
| Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit 13C6-Glucose - Glucose, Metabolism | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 25 | 2026-11-01 | 2026-09-09 |
| Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock Microaxial flow pump (left ventricular assist device), Pulmonary artery catheter, Conventional hemodynamic monitoring - Cardiogenic Shock, Acute Myocardial Infarction (AMI) | Not applicable | Recruiting | Leipzig Heart Science gGmbH | 780 | 2026-10-31 | 2026-11-09 |
| CRP Apheresis in Infarct-Related Cardiogenic Shock Selective C-reactive protein apheresis (PentraSorb®-CRP), Standard of care - Cardiogenic Shock, Acute Myocardial Infarction (AMI) | Not applicable | Recruiting | Leipzig Heart Science gGmbH | 50 | 2026-10-16 | 2026-10-27 |
| INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery Impella 5.5 SmartAssist - Heart Failure, Cardiogenic Shock | Not applicable | Recruiting | Abiomed Inc. | 250 | 2026-10-02 | 2026-11-12 |
| HOPE-Sepsis: Hemoadsorption Therapy for Sepsis Hemoperfusion with CA330 Cytokine Adsorption Column - Sepsis and Septic Shock | Not applicable | Not yet recruiting | Shanghai Zhongshan Hospital | 30 | 2026-10-01 | 2026-10-08 |
| Early Optimization of Ceftazidime Regimen in Critical Care ceftazidime, plasma ceftazidime dosage - Infection in ICU, Sepsis | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 128 | 2026-10-01 | 2026-09-16 |
| Optimal Timing of Microaxial Flow Pump(Impella CP) in AMI-related Cardiogenic Shock Routine pre-PCI Impella CP, Selective post-PCI Impella CP - Myocardial Infarction (MI), Cardiogenic Shock | Not applicable | Not yet recruiting | Chonnam National University Hospital | 126 | 2026-10-01 | 2026-09-14 |
| Fluid Balance Guided by Modified Venous Excess Ultrasonography Versus Standard Care in Patients With Acute Kidney Injury Receiving Continuous Renal Replacement Therapy mVExUS-guided fluid management - AKI - Acute Kidney Injury, Fluid Balance | Not applicable | Recruiting | Chulalongkorn University | 126 | 2026-09-30 | 2026-10-05 |
| Alterations of the Renin-angiotensin-aldosterone System in sEptic Shock Collection of fluid samples - Septic Shock | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 320 | 2026-09-15 | 2026-07-23 |
| Validation of a Capillary Leak Index During Septic Shock, Based on Haemoglobin Level Variations Induced by Fluid Resuscitation. A Pilot Study. TEST GROUP: A standardised fluid bolus of 8 mL/kg of ideal body weight using Ringer's lactate will be administered in septic shock patients., CONTROL GROUP: A standardised fluid bolus of 8 mL/kg of ideal body weight using Ringer's lactate will be administered in non-septic postoperative patients. - Sepsis | Not applicable | Not yet recruiting | University Hospital Center of Martinique | 100 | 2026-09-15 | 2026-07-29 |
| Effects of Hemoadsorption on Vascular Integrity in Septic Shock CytoSorb hemoadsorption, Standard Medical Therapy (SMT) - Septic Shock | Not applicable | Not yet recruiting | Semmelweis University | 110 | 2026-09-01 | 2026-07-17 |
| Electroacupuncture at ST36 for Reducing Postoperative Inflammation After Cardiac Surgery With Cardiopulmonary Bypass Electroacupuncture at Bilateral ST36, Acupuncture Without Electrical Stimulation at Bilateral ST36 - Systemic Inflammatory Response Syndrome (SIRS), Cardiac Surgical Procedures | Not applicable | Recruiting | Sir Run Run Shaw Hospital | 140 | 2026-09-01 | 2026-09-08 |
| Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter Study Serum - Sepsis, Septic Shock | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 210 | 2026-09-01 | 2026-08-04 |
| Feasibility of Protocolised Analgosedation in ECMO Sedation protocol - Intensive Care (ICU), Respiratory Distress Syndrome (RDS) | Not applicable | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 60 | 2026-09-01 | 2026-05-12 |
Showing 20 of 604. Sign in to see all of them.
Shock, Septic (295) · Sepsis (163) · Shock, Cardiogenic (79) · Multiple Organ Failure (57) · Systemic Inflammatory Response Syndrome (46) · Critical Illness (38) · Cytokine Release Syndrome (36) · Acute Kidney Injury (34) · Hypotension (21) · COVID-19 (20) · Wounds and Injuries (19) · Heart Failure (17) · Respiratory Distress Syndrome (15) · Respiratory Insufficiency (15)
Pathologic Processes (604) · Pathological Conditions, Signs and Symptoms (604) · Inflammation (384) · Infections (355) · Systemic Inflammatory Response Syndrome (345) · Sepsis (165) · Cardiovascular Diseases (133) · Vascular Diseases (117) · Heart Diseases (104) · Myocardial Ischemia (81) · Infarction (79) · Ischemia (79) · Necrosis (79) · Myocardial Infarction (70)
Standard of Care (17) · Norepinephrine (12) · Saline Solution (12) · Blood Specimen Collection (10) · Ascorbic Acid (7) · Continuous Renal Replacement Therapy (7) · Control Groups (6) · Epinephrine (6) · Hydrocortisone (6) · Ringer's Lactate (6) · Sodium Chloride (6) · Enteral Nutrition (5) · Plasma Exchange (5) · Thiamine (5) · Vasopressins (5)
Assistance Publique - Hôpitaux de Paris (16) · Hospices Civils de Lyon (12) · Mahidol University (10) · Mayo Clinic (7) · Southeast University, China (7) · University Hospital, Angers (7) · Efferon JSC (6) · First Affiliated Hospital of Wannan Medical College (6) · Pontificia Universidad Catolica de Chile (6) · University of Sao Paulo (6) · Ain Shams University (5) · Central Hospital, Nancy, France (5) · Centre Hospitalier Universitaire de Nīmes (5) · Centre Hospitalier Universitaire, Amiens (5) · Institute of Liver and Biliary Sciences, India (5)
France (101) · United States (94) · China (70) · Germany (39) · Egypt (21) · Italy (17) · Thailand (17) · Netherlands (14) · Russia (14) · Switzerland (14) · Canada (13) · South Korea (13) · Brazil (12) · Denmark (12) · India (12)
Alexander Supady, Dr., MPH (2) · Chairat Permpikul, MD (2) · Claire Roger (2) · Frank Bloos, MD, Ph.D. (2) · Glenn Hernandez, PhD (2) · Haibo Qiu, Doctor (2) · Holger Thiele, MD (2) · Jean Reignier, MD, PhD (2) · Jeong Hoon Yang, MD, PhD (2) · Keith Corl, MD (2) · Mahmoud S Abu-Samak, PhD (2) · Massimo Antonelli, MD (2) · Melissa J Parker, MD, MSc (2) · Min-Seok Kim (2)
PMID 28101605, PMID 34519356, PMID 10470572, PMID 11395904, PMID 15276536, PMID 16497588, PMID 16855261, PMID 17638928, PMID 18090355, PMID 18434884, PMID 18702960, PMID 19531784, PMID 20179283, PMID 21918497, PMID 22704255, PMID 22751621, PMID 23067578, PMID 23117776, PMID 23352391, PMID 23353941, PMID 23519193, PMID 23544148, PMID 23740148, PMID 23888228, PMID 23899564, PMID 24232462, PMID 24401721, PMID 24635770, PMID 24811308, PMID 25242124, PMID 25392034, PMID 26051981, PMID 26258150, PMID 26903338, PMID 27288610, PMID 27406647, PMID 28127437, PMID 28343448, PMID 28757818, PMID 28871441, PMID 29084247, PMID 29377282, PMID 30373638, PMID 36416787, PMID 40622772, PMID 41668891, PMID 9635646, PMID 10890632, PMID 11376306, PMID 11482918
2019 (2), 2004 (1), 2014 (1), K23HL171951 (1), R01GM104481 (1), R01HD053129 (1), R01HL073233 (1), R01HL121228 (1), R25TW009337 (1), U54CK000610 (1), UH3HL125119 (1)