87 completed, 85 recruiting, 62 unknown, 30 not yet recruiting. 79 Not applicable, 23 Phase 4, 18 Phase 2, 15 Phase 3, 4 Phase 1.
Follow Shock, Cardiogenic: new trials by email Literature Review of Shock, Cardiogenic trials Research Report on Shock, Cardiogenic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| French Observatory on the Management of Cardiogenic Shock 2 Cardiogenic Shock | Not yet recruiting | French Cardiology Society | 1000 | 2027-01-01 | 2026-10-09 | |
| Hong Kong Cardiogenic Shock Initiative Cardiogenic Shock Acute, STEMI - ST Elevation Myocardial Infarction | Not yet recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 320 | 2026-12-01 | 2026-09-16 | |
| INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery Impella 5.5 SmartAssist - Heart Failure, Cardiogenic Shock | Not applicable | Recruiting | Abiomed Inc. | 250 | 2026-10-02 | 2026-10-13 |
| CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock Methylprednisone, Standard of Care (SOC) - Cardiogenic Shock, Heart Failure | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 30 | 2026-10-01 | 2026-08-13 |
| Optimal Timing of Microaxial Flow Pump(Impella CP) in AMI-related Cardiogenic Shock Routine pre-PCI Impella CP, Selective post-PCI Impella CP - Myocardial Infarction (MI), Cardiogenic Shock | Not applicable | Not yet recruiting | Chonnam National University Hospital | 126 | 2026-10-01 | 2026-09-14 |
| Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill Patients Plasma H3.1 nucleosome measurement - Sepsis, Septic Shock | Not yet recruiting | Erasme University Hospital | 1000 | 2026-10-01 | 2026-09-22 | |
| Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock Microaxial flow pump (left ventricular assist device), Pulmonary artery catheter, Conventional hemodynamic monitoring - Cardiogenic Shock, Acute Myocardial Infarction (AMI) | Not applicable | Not yet recruiting | Leipzig Heart Science gGmbH | 780 | 2026-10-01 | 2026-08-24 |
| Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic Shock istaroxime, placebo - Cardiogenic Shock | Phase 2 / Phase 3 | Recruiting | Seismic Pharmaceuticals Operations LLC | 600 | 2026-09-09 | 2026-09-23 |
| Capital Offload-Shock Immediate renal replacement therapy - Hypervolemia, Cardiogenic Shock | Phase 4 | Not yet recruiting | Ottawa Heart Institute Research Corporation | 456 | 2026-09-01 | 2026-09-24 |
| Feasibility of Protocolised Analgosedation in ECMO Sedation protocol - Intensive Care (ICU), Respiratory Distress Syndrome (RDS) | Not applicable | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 60 | 2026-09-01 | 2026-05-12 |
| Prognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients. Cardiogenic Shock | Not yet recruiting | Sohag University | 150 | 2026-08-30 | 2026-08-19 | |
| Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone Dynamics Cardiogenic Shock, Euthyroid Sick Syndrome | Recruiting | Gottsegen National Cardiovascular Institute | 160 | 2026-08-17 | 2026-10-21 | |
| CRP Apheresis in Infarct-Related Cardiogenic Shock Selective C-reactive protein apheresis (PentraSorb®-CRP), Standard of care - Cardiogenic Shock, Acute Myocardial Infarction (AMI) | Not applicable | Not yet recruiting | Leipzig Heart Science gGmbH | 50 | 2026-07-20 | 2026-07-07 |
| Catheter-Oriented Unloading and Recovery With a Left Ventricular Assist Gear: Efficacy in Post Cardiotomy Cardiogenic Shock SynFlow Duro - Cardiogenic Shock | Not applicable | Recruiting | ForQaly Medical (Shanghai) Co., Ltd | 60 | 2026-07-14 | 2026-09-02 |
| COMPARE-VENT Feasibility Pilot Study Volume Controlled Mode, Pressure Controlled Mode - Respiration Failure, Cardio Vascular Disease | Not applicable | Recruiting | Mayo Clinic | 75 | 2026-07-01 | 2026-08-10 |
| Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic Shock Norepinephrine, Dopamine Agent - Cardiogenic Shock | Not applicable | Recruiting | Chonnam National University Hospital | 512 | 2026-06-16 | 2026-10-15 |
| Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK) Cardiogenic Shock Acute, Cardiogenic Shock | Recruiting | Hospital de Santa Cruz, Portugal | 800 | 2026-06-10 | 2026-06-11 | |
| Outcome of Clinical Phenotypes of Pediatric Myocarditis at Assiut University Children Hospital Standard Medical Therapy - Myocarditis, Myocarditis Acute | Not yet recruiting | Assiut University | 100 | 2026-06-01 | 2025-09-16 | |
| OPTIMIZE 5.5 - Optimizing Impella 5.5 Outcomes Through Advanced Data Science Micro-axial flow pump support - Cardiogenic Shock, Mechanical Circulatory Support | Recruiting | Medical University of Vienna | 100 | 2026-05-08 | 2026-06-01 | |
| Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm Initiation of mechanical ventilation - Cardiac Arrest (CA), Cardiogenic Shock | Not yet recruiting | Laval University | 100 | 2026-05-01 | 2026-03-20 |
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Heart Failure (46) · Myocardial Infarction (30) · Heart Arrest (26) · Shock (22) · Respiratory Distress Syndrome (15) · Acute Coronary Syndrome (13) · Shock, Septic (13) · ST Elevation Myocardial Infarction (12) · Sepsis (10) · Cardiovascular Diseases (8) · Acute Kidney Injury (7) · Heart Diseases (6) · Respiratory Insufficiency (6) · Cardiac Output, Low (4)
Necrosis (289) · Pathologic Processes (289) · Pathological Conditions, Signs and Symptoms (289) · Vascular Diseases (289) · Infarction (288) · Ischemia (288) · Myocardial Ischemia (286) · Heart Diseases (283) · Cardiovascular Diseases (281) · Shock (267) · Myocardial Infarction (259) · Respiratory Tract Diseases (23) · Lung Diseases (21) · Infections (19) · Inflammation (19)
Standard of Care (10) · Intra-Aortic Balloon Pumping (7) · Simendan (7) · Dobutamine (6) · Ivabradine (5) · Echocardiography (4) · Extracorporeal Membrane Oxygenation (4) · Hematologic Tests (3) · Istaroxime (3) · Milrinone (3) · Norepinephrine (3) · Vasoconstrictor Agents (3) · Drug Implants (2) · Ex utero Intrapartum Treatment Procedures (2) · Heparin (2)
Central Hospital, Nancy, France (12) · Assistance Publique - Hôpitaux de Paris (7) · University Hospital, Montpellier (7) · Samsung Medical Center (6) · Abiomed Inc. (5) · Beijing Anzhen Hospital (5) · University Hospital, Strasbourg, France (5) · Erasmus Medical Center (4) · National Taiwan University Hospital (4) · Niguarda Hospital (4) · Ottawa Heart Institute Research Corporation (4) · Assistance Publique Hopitaux De Marseille (3) · Charite University, Berlin, Germany (3) · Chonnam National University Hospital (3) · Copenhagen University Hospital, Rigshospitalet (3)
France (61) · United States (48) · Germany (35) · China (20) · Italy (20) · Canada (13) · Netherlands (13) · South Korea (13) · Czechia (10) · Poland (9) · Spain (8) · Belgium (7) · Switzerland (7) · United Kingdom (7) · Denmark (6)
Holger Thiele, MD (4) · Carsten Skurk, MD (3) · Tharusan Thevathasan, MD (3) · David D'Alessandro, MD (2) · Filio Billia, MD PhD (2) · Jeong Hoon Yang, MD, PhD (2) · Louise Rose, PhD (2) · Marco Maggiorini (2) · Min-Seok Kim (2) · Sarah Thordsen, MD (2) · William W O'Neill, MD (2)
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