11 completed, 4 recruiting, 2 not yet recruiting, 2 withdrawn. 11 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Recruiting 4, Not yet recruiting 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Quality of Life in Patients With Post-Sepsis Syndrome Efferon LPS - Sepsis | Not yet recruiting | Efferon JSC | 300 | 2026-11-01 | 2026-10-22 | |
| Efferon LPS Hemoadsorption in in Patients With Thermal Burns Efferon LPS - Burns | Not applicable | Recruiting | Efferon JSC | 50 | 2026-10-21 | 2026-10-23 |
| Efferon LPS Hemoadsorption in Cardiac Surgery Patients Efferon LPS - Cardiac Disease, Multiple Organ Dysfunction Syndrome | Not applicable | Recruiting | Efferon JSC | 60 | 2026-04-22 | 2026-08-26 |
| Efferon LPS Hemoadsorption in Patients With Acute Pancreatitis Efferon LPS - Pancreatitis, Acute | Not applicable | Recruiting | Efferon JSC | 150 | 2026-03-30 | 2026-04-07 |
| Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Ulcerative Colitis and Crohn Disease Efferon LPS - Crohn Disease, Ulcerative Colitis | Not applicable | Not yet recruiting | Efferon JSC | 40 | 2026-03-01 | 2026-02-11 |
| Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Thermal Burns Efferon LPS - Burns | Withdrawn | Efferon JSC | 2025-12-08 | 2026-10-19 | ||
| Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Thermal Burns Efferon LPS NEO - Burns | Withdrawn | Efferon JSC | 2025-10-01 | 2026-10-19 | ||
| Efferon CT Hemoadsorption for Cardiogenic Shock in Acute Myocardial Infarction Efferon CT - Myocardial Infarction, Cardiogenic Shock | Not applicable | Recruiting | Efferon JSC | 60 | 2025-04-29 | 2026-08-26 |
| Hemoperfusion Efferon LPS During Cardiac Surgery Using Cardiopulmonary Bypass Efferon LPS - Cardiac Disease, Multiple Organ Dysfunction Syndrome | Not applicable | Terminated | Efferon JSC | 14 | 2024-11-11 | 2025-12-09 |
| Hemoperfusion With Efferon CT for the Treatment of Patients With Severe Psoriasis Efferon CT - Psoriasis | Not applicable | Completed | Efferon JSC | 60 | 2024-10-22 | 2025-11-24 |
| Clearance of Antibacterial Agents During Hemoperfusion in Patients With Sepsis Sepsis, Septic Shock | Completed | Efferon JSC | 30 | 2024-10-21 | 2025-12-02 | |
| Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Sepsis Efferon LPS NEO - Sepsis, Septic Shock | Not applicable | Completed | Efferon JSC | 78 | 2023-01-01 | 2025-06-05 |
| Combination of Cytokine Hemosorption and High-volume Hemofiltration in Acute Pancreatitis Efferon CT - Acute Pancreatitis Without Necrosis or Infection | Not applicable | Completed | Efferon JSC | 28 | 2022-11-01 | 2026-09-11 |
| Combined Hemoperfusion and Therapeutic Plasma Exchange for Treatment of Patients With Septic Shock Efferon LPS, Efferon CT - Sepsis, Septic Shock | Completed | Efferon JSC | 82 | 2022-05-01 | 2024-06-05 | |
| Selective Lipopolysaccharide Hemosorption in Maternal Sepsis Efferon LPS - Maternal sepsIs | Not applicable | Completed | Efferon JSC | 30 | 2022-01-01 | 2024-06-25 |
| Hemoperfusion Efferon СT for the Treatment of Patients With Acute Pancreatitis Efferon CT - Acute Pancreatitis With Uninfected Necrosis, Unspecified | Completed | Efferon JSC | 34 | 2022-01-01 | 2024-02-21 | |
| Lipopolysaccharide Adsorption At Septic Shock Efferon LPS hemoperfusion - Septic Shock | Not applicable | Completed | Efferon JSC | 58 | 2021-03-23 | 2024-09-19 |
| Hemoperfusion With the Efferon CT Extracorporeal Adsorbers in Patients With Severe Covid-19 Efferon CT - COVID-19 | Completed | Efferon JSC | 42 | 2020-10-01 | 2021-11-03 | |
| Hemoperfusion Efferon СT for the Extremely Severe Form of COVID-19 Efferon CT therapy - COVID-19 | Completed | Efferon JSC | 130 | 2020-10-01 | 2025-03-26 | |
| Efferon LPS Hemoperfusion for Treatment of Patients With Septic Shock Efferon LPS - Septic Shock | Completed | Efferon JSC | 9 | 2019-09-13 | 2021-06-03 |
Sepsis (6) · Shock, Septic (6) · Burns (3) · Pancreatitis (3) · COVID-19 (2) · Heart Diseases (2) · Intraabdominal Infections (2) · Multiple Organ Failure (2) · Colitis, Ulcerative (1) · Crohn Disease (1) · Infections (1) · Inflammatory Bowel Diseases (1) · Myocardial Infarction (1) · Pregnancy Complications, Infectious (1) · Psoriasis (1)
Russia (20)
Vladimir Kulabukhov, PhD, MD (3) · Timur Kim, MD (2) · Vladimir Kiselev, PhD, MD (2) · Alexander Mezhin, PhD, MD (1) · Alexey Pyregov, PhD, MD (1) · Igor Afukov, PhD, MD (1) · Igor Bakulin, PhD, MD (1) · Igor Samatov, PhD, MD (1) · Ivan Afukov, PhD, MD (1) · Konstantin Raznatovsky, PhD, MD (1) · Makariy Mendibaev, MD (1) · Nikolai Krotenko, PhD, MD (1) · Sergei Stepanenko, PhD, MD (1) · Sergey Rey, MD, PhD (1) · Sergey Rey, PhD, MD (1)
PMID 10227782, PMID 17448226, PMID 19684388, PMID 20519906, PMID 23860248, PMID 24249974, PMID 24503765, PMID 26903335, PMID 27807819, PMID 28249176, PMID 28343448, PMID 30835303, PMID 31131109