50 completed. 50 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 50 | Completed 50 |
Follow Respiratory Insufficiency: new trials by email Literature Review of Respiratory Insufficiency trials Research Report on Respiratory Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic Rhinitis Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg, Oxymetazoline 0.05% nasal solution - Persistent Allergic Rhinitis | Phase 4 | Completed | Dr. Behcet Uz Children's Hospital | 76 | 2025-01-02 | 2026-05-18 |
| Comparison of Gas Exchange Between Two Invasive Mechanical Ventilation Modes in Children Respiratory support a, Respiratory support b - Respiratory Failure | Phase 4 | Completed | University Children's Hospital, Zurich | 59 | 2024-01-15 | 2024-12-13 |
| Respiratory Depression of Remimazolam vs. Propofol for Monitored Anesthesia Care Propofol, Remimazolam - Propofol, Remimazolam | Phase 4 | Completed | DongGuk University | 76 | 2023-08-24 | 2025-07-22 |
| Oliceridine in Patients With Acute Burn Injuries Oliceridine, Historical opioid use - Acute Pain, Burns | Phase 4 | Completed | University of Tennessee | 31 | 2023-04-01 | 2023-10-26 |
| Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy Ciprofol, Propofol, Sufentanil - Bronchoscopy, Procedural Sedation | Phase 4 | Completed | Wenzhou Central Hospital | 100 | 2022-08-01 | 2026-08-04 |
| High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Failure. L Carnitine ( low dose), L-Carnitine ( high dose) - Respiratory Failure | Phase 4 | Completed | Ain Shams University | 60 | 2022-04-15 | 2022-10-17 |
| Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery Tranexamic Acid 1,000 Mg/10 mL (100 Mg/mL) INTRAVEN VIAL (ML) - Chronic Sinusitis, Nasal Obstruction | Phase 4 | Completed | Stanford University | 40 | 2021-06-17 | 2023-04-05 |
| Sedation Complications in Urology During Spinal Anesthesia With Dexmedetomidine or Midazolam Regarding OSA Risk Spinal anesthesia with intraoperative dexmedetomidine sedation, Spinal anesthesia with intraoperative midazolam sedation, Dexmedetomidine - Anesthesia, Anesthesia Complication | Phase 4 | Completed | University Hospital of Split | 115 | 2021-04-01 | 2022-04-08 |
| Low or High Dose of Dexamethasone in Patients With Respiratory Failure by COVID-19 Dexamethasone high dose, Dexamethasone low dose - Covid19, Corticosteroids | Phase 4 | Completed | Manuel Taboada Muñiz | 198 | 2021-01-15 | 2021-10-20 |
| Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery Evaluation of Diaphragm Movement - Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block | Phase 4 | Completed | Alper Tunga Dogan | 50 | 2020-12-01 | 2021-11-30 |
| Handling Oxygenation Targets in COVID-19 Low oxygenation target, High oxygenation target - Hypoxemic Respiratory Failure, Oxygen Toxicity | Phase 4 | Completed | Aalborg University Hospital | 726 | 2020-08-25 | 2024-07-15 |
| Cholecalciferol to Improve the Outcomes of COVID-19 Patients Vitamin D, Placebo - COVID | Phase 4 | Completed | Vitamin D Study Group | 218 | 2020-08-11 | 2021-07-30 |
| Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions Dexamethasone - Acute Hypoxemic Respiratory Failure | Phase 4 | Completed | Hospital Universitario de Gran Canaria Doctor Negrín | 980 | 2020-07-06 | 2026-09-18 |
| BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19 BNO 1030, Standard care - Covid19, Nasopharyngitis | Phase 4 | Completed | Ivano-Frankivsk National Medical University | 133 | 2020-05-01 | 2021-03-15 |
| The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium cisatracurium - Critical Illness, Respiratory Distress Syndrome, Adult | Phase 4 | Completed | Mahidol University | 10 | 2017-12-15 | 2019-03-06 |
| Effects of Tapentadol Versus Oxycodone After Hysterectomy. Tapentadol, Oxycodone - Pain, Postoperative, Pain Uterus | Phase 4 | Completed | Oslo University Hospital | 86 | 2017-12-04 | 2019-04-04 |
| Handling Oxygenation Targets in the Intensive Care Unit Oxygen - Hypoxemic Respiratory Failure, Oxygen Toxicity | Phase 4 | Completed | Aalborg University Hospital | 2928 | 2017-06-19 | 2021-10-26 |
| Effect of Neuromuscular Blockade and Reversal on Breathing Sugammadex, Neostigmine, Placebo - Respiratory Insufficiency | Phase 4 | Completed | Leiden University Medical Center | 46 | 2016-09-01 | 2020-02-19 |
| The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation Triamcinolone Acetonide, Ayr saline nasal mist - Nasal Obstruction | Phase 4 | Completed | Stanford University | 42 | 2016-08-01 | 2020-08-13 |
| The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine. Naloxone, Placebo - Respiratory Depression | Phase 4 | Completed | University College Dublin | 96 | 2016-04-01 | 2017-12-19 |
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Nasal Obstruction (11) · Agnosia (3) · Critical Illness (3) · Pain (3) · Pulmonary Disease, Chronic Obstructive (3) · Respiratory Aspiration (3) · Respiratory Distress Syndrome (3) · Acute Pain (2) · Airway Obstruction (2) · COVID-19 (2) · Hypoxia (2) · Pain, Postoperative (2) · Rhinitis, Allergic, Seasonal (2) · Rhinorrhea (2)
Respiration Disorders (50) · Respiratory Tract Diseases (50) · Pathological Conditions, Signs and Symptoms (22) · Signs and Symptoms (15) · Pathologic Processes (14) · Otorhinolaryngologic Diseases (12) · Airway Obstruction (11) · Lung Diseases (11) · Nose Diseases (11) · Neurologic Manifestations (10) · Infections (7) · Signs and Symptoms, Respiratory (7) · Disease Attributes (6) · Nervous System Diseases (6)
Propofol (3) · Acetaminophen (2) · Acetazolamide (2) · Dexamethasone (2) · Dexmedetomidine (2) · Fentanyl (2) · Midazolam (2) · Neostigmine (2) · Oxygen (2) · Oxymetazoline (2) · Pseudoephedrine (2) · Standard of Care (2) · Sugammadex (2) · levocetirizine (2) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1)
Aalborg University Hospital (2) · Hospital Clinic of Barcelona (2) · Leiden University Medical Center (2) · Mahidol University (2) · Stanford University (2) · UCB Pharma (2) · Ain Shams University (1) · Alper Tunga Dogan (1) · Althaia Xarxa Assistencial Universitària de Manresa (1) · Ass.-Prof. PD Dr. Klaus Ulrich Klein (1) · Association pour la Recherche en Physiologie de l'Environnement (1) · B. Braun Medical SA (1) · DongGuk University (1) · Dr. Behcet Uz Children's Hospital (1) · Dr. Josip Benčević General Hospital (1)
United States (8) · Spain (5) · Norway (4) · Switzerland (4) · Netherlands (3) · Turkey (Türkiye) (3) · Croatia (2) · Denmark (2) · Italy (2) · Thailand (2) · United Kingdom (2) · Argentina (1) · Austria (1) · Belgium (1) · China (1)
Bodil Steen Rasmussen, MD, PhD (2) · Albert Dahan, MD, PhD, Professor (1) · Anders Perner, MD, PhD (1) · Benjamin Benzon (1) · Bozidar Duplancic (1) · Carlos Tajer, MD (1) · Cenk Kirakli, MD (1) · Christian Mueller, Prof (1) · Chu C Lin, MD (1) · Dr. Sarath Chandra Sistla, M.S., (1) · Eduardo Marquez, MD (1) · Elisabeth A Kruse, PhD (1)
PMID 38990335, PMID 40920961, PMID 10712328, PMID 16394778, PMID 18388356, PMID 18719057, PMID 21036778, PMID 21047406, PMID 21333087, PMID 22678319, PMID 23578004, PMID 24837977, PMID 25504992, PMID 25742308, PMID 28257388, PMID 28487139, PMID 28632682, PMID 28679605, PMID 28917549, PMID 29284510, PMID 29634491, PMID 31541010, PMID 31792949, PMID 32422305, PMID 32659856, PMID 33428347, PMID 33471452, PMID 33522946, PMID 34425016, PMID 34674834, PMID 34916266, PMID 35065599, PMID 35441849, PMID 35622854, PMID 36608352, PMID 37196799, PMID 37588787, PMID 38501214, PMID 38711834, PMID 39303806, PMID 39800404, PMID 42843159
2017 (2)