286 completed, 26 terminated, 10 unknown, 9 withdrawn. 127 Phase 3, 79 Phase 2, 50 Phase 4, 36 Phase 1, 21 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Bimekizumab in Adults With Pyoderma Gangrenosum Bimekizumab - Pyoderma Gangrenosum | Phase 2 | Not yet recruiting | Oregon Health and Science University | 15 | 2026-09-01 | 2026-08-17 |
| Epilepsy Emergency Department High Utilizer Program CHW-Led Transition-of-Care Intervention - Epilepsy, Uncontrolled Seizures | Enrolling by invitation | Morehouse School of Medicine | 15 | 2026-05-01 | 2026-06-23 | |
| EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment fenfluramine HCl - Lennox Gastaut Syndrome (LGS) | Enrolling by invitation | University of Chicago | 20 | 2026-05-01 | 2026-08-06 | |
| Clinical Utility of Reduced EEG Home Monitoring in Fenfluramine Titration for Dravet and LGS Byteflies Remote patient monitoring solution (with reduced EEG) - Dravet Syndrome (DS), Lennox Gastaut Syndrome (LGS) | Not applicable | Enrolling by invitation | Byteflies | 20 | 2026-04-20 | 2026-10-08 |
| Detecting Fatigue From Voice in Generalised Myasthenia Gravis Myasthenia Gravis Generalised | Not yet recruiting | Thymia Limited | 240 | 2026-02-01 | 2026-01-28 | |
| Zilucoplan for Severe gMG Exacerbations Zilucoplan® - Generalized Myasthenia Gravis (gMG) | Phase 3 | Recruiting | Miriam Freimer | 15 | 2026-01-20 | 2026-08-28 |
| Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment Social media recruitment, Self-Assessment, Follow-up - Myasthenia Gravis, Neuromuscular Disease | Recruiting | ZS Associates | 1000 | 2025-02-26 | 2025-03-10 | |
| Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency Doxecitine and Doxribtimine - Thymidine Kinase 2 (TK2 ) Deficiency, Mitochondrial Myopathies | Phase 2 | Recruiting | Cristina Domínguez González | 15 | 2025-01-01 | 2026-09-17 |
| Bimekizumab in Plaque Psoriasis Bimekizumab - Plaque Psoriasis | Phase 4 | Completed | Icahn School of Medicine at Mount Sinai | 60 | 2024-06-03 | 2026-04-20 |
| Expediting Myasthenia Gravis (MG) Diagnostic Evaluation: A Novel, Proof-of-Concept for Undiagnosed, Symptomatic Patients That Uses Social Media Targeting and Self-Assessment Social media recruitment, Self-Assessment, Follow-up - Myasthenia Gravis, Neuromuscular Manifestations | Completed | ZS Associates | 215 | 2024-03-28 | 2025-03-25 | |
| Digital Solution to Improve Cognitive Function in Epilepsy: PRODDIGE Project cognitive rehabilitation - Cognitive Change | Not applicable | Unknown | Central Hospital, Nancy, France | 90 | 2021-10-01 | 2021-09-27 |
| Personalized Parkinson Project PSP Cohort Verily Study Watch - Progressive Supranuclear Palsy, Brain Diseases | Completed | Radboud University Medical Center | 100 | 2021-05-01 | 2025-03-24 | |
| The Personalized Parkinson Project De Novo Cohort Verily Study Watch - Parkinson Disease, Parkinsonian Disorders | Active not recruiting | Radboud University Medical Center | 103 | 2020-08-29 | 2025-03-24 | |
| Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen Repository Hidradenitis Suppurativa | Recruiting | University of California, San Francisco | 3000 | 2020-08-01 | 2026-04-29 | |
| Evaluation of a New Communication Aid Tool to Favor Global Patient Centered Care Consulting with PARKINSUN as communication aid-tool, Consulting without PARKINSUN as communication aid-tool - Parkinson's Disease | Not applicable | Recruiting | University Hospital, Lille | 120 | 2020-07-21 | 2025-12-23 |
| Clinical Scenarios for Long-term Monitoring of Epileptic Seizures With a Wearable Biopotential Technology Sensor Dot - Epilepsy | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 496 | 2020-06-22 | 2022-11-08 |
| Zilucoplan® in Improving Oxygenation, Short-, Longterm Outcome of COVID19 Patients With Acute Hypoxic Respiratory Failure Zilucoplan®, Placebo - COVID-19 | Phase 2 | Completed | University Hospital, Ghent | 81 | 2020-05-22 | 2023-09-14 |
| CLassification of Axial SpondyloarthritiS Inception Cohort Spondyloarthritis | Completed | Spondyloarthritis Research and Treatment Network | 501 | 2019-12-04 | 2022-12-08 | |
| An Investigation of Levetiracetam in Alzheimer's Disease Levetiracetam, Placebo Oral Tablet - Alzheimer Disease, Epilepsy | Phase 2 | Completed | University of Oxford | 8 | 2018-10-28 | 2024-04-24 |
| Brivaracetam: a Prospective and Multicentre Post-marketing Observational Study Brivaracetam - Epilepsy | Completed | Centre hospitalier de l'Université de Montréal (CHUM) | 51 | 2018-10-04 | 2023-12-19 |
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Epilepsy (70) · Arthritis, Rheumatoid (31) · Parkinson Disease (29) · Crohn Disease (25) · Seizures (20) · Epilepsies, Partial (19) · Lupus Erythematosus, Systemic (14) · Restless Legs Syndrome (12) · Rhinitis, Allergic, Seasonal (11) · Diabetic Neuropathies (9) · Rhinitis (6) · Anxiety Disorders (5) · Chronic Urticaria (5) · Myasthenia Gravis (5) · Psoriasis (5)
Levetiracetam (70) · Certolizumab Pegol (48) · rotigotine (36) · Lacosamide (34) · levocetirizine (28) · 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (18) · brivaracetam (17) · epratuzumab (12) · Inotuzumab Ozogamicin (8) · Rituximab (4) · olokizumab (4) · Cetirizine (3) · Methotrexate (3) · Seletracetam (3) · carbidopa, levodopa drug combination (3)
United States (163) · Germany (96) · France (56) · United Kingdom (54) · Spain (53) · Belgium (52) · Poland (45) · Italy (39) · Canada (38) · Czechia (36) · Hungary (34) · Russia (27) · Mexico (26) · Australia (23) · Netherlands (23)
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PMID 33687069, PMID 29246162, PMID 35285519, PMID 18619874, PMID 24006953, PMID 26899665, PMID 27265725, PMID 33461041, PMID 34218211, PMID 17283312, PMID 17634466, PMID 19015207, PMID 19327967, PMID 19877104, PMID 20547658, PMID 20819318, PMID 21090839, PMID 21095488, PMID 21484766, PMID 22341962, PMID 22413944, PMID 22589265, PMID 26238672, PMID 26353833, PMID 26414341, PMID 26446245, PMID 26882318, PMID 27335114, PMID 27589414, PMID 27598855, PMID 27608437, PMID 27988967, PMID 28236727, PMID 28279891, PMID 29381843, PMID 29414542, PMID 29486396, PMID 29908435, PMID 31937513, PMID 32100960, PMID 32432339, PMID 33231879, PMID 33780735, PMID 34033237, PMID 34155568, PMID 35582748, PMID 35622074, PMID 38788664, PMID 14625037, PMID 15966463
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