254 completed, 156 unknown, 114 recruiting, 33 not yet recruiting. 206 Not applicable, 92 Phase 2, 69 Phase 4, 54 Phase 3, 42 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exercise and Prolonged Fasting to Improve Brown Adipose Tissue Function in Postmenopausal Women Aerobic exercise, Prolonged fasting - Cardiometabolic Diseases, Postmenopause | Not applicable | Not yet recruiting | Universidad de Almeria | 60 | 2027-09-01 | 2026-09-23 |
| Efficacy of Zoster Vaccination in Glioblastoma Patients Additional vaccination against shingles (herpes zoster), Standard of care treatment without additional vaccination - Glioblastoma (GBM) | Phase 4 | Not yet recruiting | University Hospital, Essen | 230 | 2027-01-02 | 2026-04-23 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Psilocybin-Assisted Psychotherapy for Veterans With PTSD Psilocybin-assisted Psychotherapy - Posttraumatic Stress Disorder (PTSD) | Phase 2 | Not yet recruiting | ARQ National Psychotrauma Centre | 12 | 2026-12-01 | 2026-08-28 |
| Efficacy, Safety and Tolerability of Low Sodium Oxybate for Nocturnal Cluster Headache Attacks Low Sodium Oxybate, Placebo - Chronic Cluster Headache | Phase 2 | Not yet recruiting | Leiden University Medical Center | 52 | 2026-12-01 | 2026-08-25 |
| Reduced-Dose Versus Full-Dose Alteplase for High-Risk Pulmonary Embolism Reduced-dose alteplase, Full-dose alteplase - Pulmonary Embolism Acute | Phase 4 | Not yet recruiting | Sahlgrenska University Hospital | 400 | 2026-12-01 | 2026-09-17 |
| Flap Assessment With Regional Oximetry for Early Detection of Compromise in Free Flap Reconstructive Surgery - FLARE Study Elective free flap surgery, INVOS monitoring - Reconstructive Surgery, Flap Monitoring | Not yet recruiting | Leiden University Medical Center | 100 | 2026-12-01 | 2026-10-21 | |
| RADICAL-IO: thRee Cycles of immunotherApy Without raDical Therapy In mediCALly InOperable Stage I Non-small Cell Lung Cancer Cemiplimab 350 mg IV - Non Small Cell Lung Cancer, Immunotherapy | Phase 2 | Not yet recruiting | The Netherlands Cancer Institute | 30 | 2026-11-01 | 2026-10-05 |
| AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery Ovarian Cancer, Ovarian Tumor | Not yet recruiting | Catharina Ziekenhuis Eindhoven | 1300 | 2026-11-01 | 2026-10-20 | |
| Surgery Versus Stereotactic Ablative Radiotherapy for Patients With Locally Advanced Pancreatic Cancer With Favourable Biological Response Following Induction Chemotherapy Pancreatic surgery, MRI guided stereotactic ablative radiotherapy - Locally Advanced Pancreatic Carcinoma (LAPC) | Phase 3 | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 230 | 2026-10-01 | 2026-10-09 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| A Step Forward for Unraveling the Immune Mechanisms and Tools for Tuberculosis Spectrum Management Tuberculosis | Not yet recruiting | Irene Latorre Rueda | 940 | 2026-09-01 | 2026-07-30 | |
| SPECTATOR: Perfusion Monitoring Before, During and After Lower Extremity Revascularization With Laser Speckle Contrast Imaging Laser Speckle Contrast Imaging - Vascular Disease，Peripheral | Recruiting | Leiden University Medical Center | 30 | 2026-09-01 | 2026-09-23 | |
| Therapy Adjustment and IndividuaLized Response With Biomarker Observation in ReaL-world Heart Failure Chronic Heart Failure, Acute Decompensated Heart Failure | Not yet recruiting | Maastricht University Medical Center | 600 | 2026-09-01 | 2026-06-15 | |
| Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial Phototherapy, Exchange Transfusion - Neonatal Hyperbilirubinemia, Treatment Decisions | Not applicable | Not yet recruiting | University Medical Center Groningen | 680 | 2026-08-01 | 2026-06-29 |
| COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green Laser Speckle Contrast Imaging - Leakage, Anastomotic, Colon Cancer | Not yet recruiting | Leiden University Medical Center | 30 | 2026-08-01 | 2026-07-22 | |
| How Differences in the Composition of Microorganisms in the Soil Affect the Microorganisms in the Human Gut, Through the Vegetables That Grow in it: a Process Pilot Study With Healthy Participants Low diversity vegetable smoothie, High diversity vegetable smoothie - Pilot Study | Not applicable | Not yet recruiting | Leiden University Medical Center | 10 | 2026-08-01 | 2026-08-03 |
| Percutaneous Versus EUS-guided Drainage of Symptomatic Fluid Collections After Left Pancreatectomy Plastic double pigtail stent, Percutaneous catheter - Symptomatic Fluid Collection(s) | Not applicable | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 96 | 2026-08-01 | 2026-08-04 |
| Patient-Ventilator Asynchrony: Occurence and Clinical Impact in Usual Care PVA classification software - Mechanical Ventilation, Patient-Ventilator Asynchrony | Recruiting | Erasmus Medical Center | 110 | 2026-07-21 | 2026-08-13 | |
| Coping Strategies, Loneliness, and Resilience in Patients With Dermatosis Questionnaires - Skin Disease, Skin Disorder | Not applicable | Not yet recruiting | University Hospital, Brest | 375 | 2026-07-01 | 2026-06-10 |
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COVID-19 (15) · Colorectal Neoplasms (13) · Cardiovascular Diseases (12) · Neoplasms (12) · Pancreatic Neoplasms (11) · Disease (10) · Pain (10) · Arthritis, Rheumatoid (9) · Diabetes Mellitus (9) · Schistosomiasis (9) · Malaria (8) · Pulmonary Embolism (8) · Rectal Neoplasms (8) · Urinary Tract Infections (8) · Colonic Neoplasms (7)
Surveys and Questionnaires (7) · Cyclophosphamide (5) · Standard of Care (5) · Bevacizumab (4) · Carboplatin (4) · Methotrexate (4) · Methylprednisolone (4) · Mycophenolic Acid (4) · Observation (4) · Prednisolone (4) · Radiotherapy (4) · Rocuronium (4) · Aclarubicin (3) · Blood Specimen Collection (3) · Cognitive Behavioral Therapy (3)
Netherlands (521) · Belgium (32) · Germany (31) · Italy (29) · United Kingdom (29) · Spain (27) · France (24) · Sweden (18) · Switzerland (15) · United States (14) · Austria (12) · Denmark (12) · Czechia (9) · Greece (9) · Canada (8)
Albert Dahan, MD PhD (3) · Andrea WM Evers, Prof. Dr. (3) · Ellen Kapiteijn, MD, PhD (3) · Hans Gelderblom, MD, PhD (3) · Marieke JH Wermer, MD PhD (3) · Meta Roestenberg, MD, PhD (3) · Peter J. Sterk, MD, PhD (3) · AJ Gelderblom, Prof (2) · Abraham Schoe, MD, PhD (2) · Albert Dahan, MD, PhD, Professor (2) · Alejandra Mendez Romero, MD PhD (2) · Anke Versluis, Dr. (2) · Axel Haverich, Prof. Dr. (2) · Darius Soonawala, MD (2)
PMID 23349326, PMID 24251360, PMID 25131735, PMID 28063245, PMID 29806553, PMID 33293204, PMID 35040231, PMID 36262060, PMID 36721961, PMID 39641307, PMID 39963952, PMID 40243391, PMID 42261111, PMID 10373119, PMID 10459972, PMID 16126057, PMID 16431890, PMID 16751327, PMID 17331245, PMID 17379851, PMID 17921381, PMID 17921396, PMID 18039368, PMID 18184122, PMID 18349315, PMID 1842936, PMID 18433464, PMID 18551082, PMID 18558641, PMID 19001507, PMID 19066296, PMID 19201123, PMID 19641203, PMID 19664226, PMID 19773371, PMID 19841453, PMID 20157582, PMID 20181032, PMID 20215360, PMID 20395876, PMID 20484486, PMID 20684711, PMID 21098770, PMID 21304982, PMID 21316664, PMID 21729098, PMID 21853099, PMID 22066583, PMID 22197856, PMID 23186785
2019 (5), 2023 (5), 2015 (4), 2016 (3), 2018 (3), 2009 (2), 2025 (2), U01NS101944 (1), U01NS137702 (1)