17 completed, 14 unknown, 8 recruiting, 5 not yet recruiting. 21 Not applicable, 13 Phase 4, 2 Phase 1, 2 Phase 2, 1 Early Phase 1.
Follow Remimazolam: new trials by email Literature Review of Remimazolam trials Research Report on Remimazolam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient-controlled Remimazolam Sedation Under Spinal Anesthesia Patient-controlled sedation, Clinician-controlled sedation - Hip Arthroplasty, Spinal Anesthesia | Not applicable | Not yet recruiting | Seoul National University Hospital | 104 | 2026-10-01 | 2026-09-23 |
| Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy Fentanyl and Propofol, Esketamine and remimazolam - Adverse Respiratory Events, Hypoxemia | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Wenzhou Medical University | 120 | 2026-08-01 | 2026-08-06 |
| Efficacy and Safety of Eleveld PK/PD Model-based Dosing During General Anesthesia Eleveld model-guided dosing, Standard weight-based label dosing - Remimazolam, Pharmacokinetics and Pharmacodynamics | Phase 4 | Recruiting | Seoul National University Hospital | 68 | 2026-07-05 | 2026-09-29 |
| Remimazolam on the Incidence of Postoperative Acute Kidney Injury Remimazolam (Byfavo), propofol - Remimazolam, Propofol | Not applicable | Not yet recruiting | Seoul National University Bundang Hospital | 78 | 2026-06-26 | 2026-06-29 |
| Remimazolam NeuroImaging Remimazolam, Peripheral Nerve Stimulation - Anesthesia, Pain | Early Phase 1 | Recruiting | Keith M Vogt | 60 | 2026-03-27 | 2026-04-02 |
| Remimazolam TIVA-Flumazenil Antagonism in Short-duration ENT Surgeries Remimazolam, Total Intravenous Anesthesia | Completed | Tongji Hospital | 511 | 2026-03-09 | 2026-05-11 | |
| The Effect of Reversal of Remimazolam Sedation With Flumazenil on Cognitive Function in Patients Undergoing Hip Arthroplasty Under Spinal Anesthesia remimazolam sedation reversal with flumazenil, placebo - Postoperative Delirium, Sedation | Phase 4 | Not yet recruiting | Medical University of Gdansk | 150 | 2026-01-01 | 2026-01-06 |
| Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation remimazolam group, dexmedetomidine group, esketamine group - Remimazolam, Dexmedetomidine | Not applicable | Recruiting | Maternal and Child Health Hospital of Hubei Province | 150 | 2025-04-01 | 2025-07-10 |
| The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function Remimazolam, propofol - Cognitive Functioning, Propofol | Not applicable | Not yet recruiting | The Second Affiliated Hospital of Chongqing Medical University | 174 | 2025-02-24 | 2025-02-14 |
| Remimazolam Besylate in Sedation of Postcardioperative Patients Remimazolam, Propofol - Remimazolam, Propofol | Not applicable | Recruiting | First Affiliated Hospital of Zhejiang University | 120 | 2025-02-10 | 2025-02-18 |
| Remimazolam and Emergence Delirium in Pediatrics Remimazolam, Normal Saline - Pediatric, Neurosurgery | Phase 4 | Recruiting | Peking University First Hospital | 248 | 2025-01-01 | 2025-07-01 |
| The EEG Study Under Remimazolam Anesthesia in Children Electroencephalography, Remimazolam | Recruiting | Second Affiliated Hospital of Wenzhou Medical University | 60 | 2024-11-22 | 2025-02-06 | |
| RCT Comparing Remimazolam With Propofol Under EEG DSA Guidance During Cardiac Electrophysiology Studies and Ablation Propofol, Remimazolam, With intubation and controlled ventilation to maintain airway - Hemodynamic, Remimazolam | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 200 | 2024-09-20 | 2024-11-22 |
| The Effect of Wavelet Index in Monitoring the Sedation Depth of Remimazolam Besylate Remimazolam besylate - Remimazolam, Anesthesia Awareness | Unknown | Beijing Chao Yang Hospital | 30 | 2024-08-15 | 2024-06-25 | |
| Flumazenil Antagonism of Remimazolam in Kidney Transplant Patients Flumazenil Injection（F1 group）, Flumazenil Injection（F2 group）, Saline（C group） - Flumazenil to Antagonize Remimazolam, Remimazolam | Phase 1 | Unknown | Qianfoshan Hospital | 60 | 2024-07-01 | 2024-08-01 |
| Remimazolam for Emergence Delirium Prevention in Children Undergoing Tonsillectomy Remimazolam 20 MG Injection [Byfavo], NaCl (0,9%) - Remimazolam, Tonsillectomy | Phase 1 | Completed | University Hospital of Split | 110 | 2024-04-01 | 2026-07-15 |
| Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty Remimazolam 20 MG Injection [Byfavo], NaCl 0.9% - Remimazolam, Emergence Delirium | Phase 2 | Unknown | University Hospital of Split | 80 | 2024-03-06 | 2024-05-03 |
| Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Byfavo, Midazolam - Midazolam, Remimazolam | Phase 2 | Unknown | Yeungnam University Hospital | 330 | 2024-03-01 | 2024-02-23 |
| Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam Flumazenil, normal saline - Flumazenil Adverse Reaction, Remimazolam | Not applicable | Recruiting | Pusan National University Yangsan Hospital | 24 | 2023-09-19 | 2025-09-12 |
| Respiratory Depression of Remimazolam vs. Propofol for Monitored Anesthesia Care Propofol, Remimazolam - Propofol, Remimazolam | Phase 4 | Completed | DongGuk University | 76 | 2023-08-24 | 2025-07-22 |
Showing 20 of 45. Sign in to see all of them.
Emergence Delirium (5) · Acute Kidney Injury (1) · Aortic Valve Stenosis (1) · Arrhythmias, Cardiac (1) · Breast Diseases (1) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Hypoxia (1) · Intraoperative Awareness (1) · Myocardial Infarction (1) · Myocardial Ischemia (1) · Obesity, Morbid (1) · Osteoarthritis, Knee (1) · Pain (1) · Parathyroid Diseases (1)
Pathological Conditions, Signs and Symptoms (12) · Pathologic Processes (9) · Signs and Symptoms (9) · Neurologic Manifestations (6) · Postoperative Complications (6) · Confusion (5) · Delirium (5) · Mental Disorders (5) · Nervous System Diseases (5) · Neurobehavioral Manifestations (5) · Neurocognitive Disorders (5) · Heart Diseases (3) · Cardiovascular Diseases (2) · Aortic Valve Disease (1) · Arterial Occlusive Diseases (1)
remimazolam (27) · Propofol (14) · Midazolam (4) · Dexmedetomidine (3) · Fentanyl (3) · Flumazenil (3) · cisatracurium (3) · Esketamine (2) · Injections (2) · Long-Term Synaptic Depression (2) · Saline Solution (2) · Sevoflurane (2) · Sufentanil (2) · Control Groups (1) · Flurbiprofen (1)
Asan Medical Center (4) · Pusan National University Yangsan Hospital (4) · Seoul National University Bundang Hospital (4) · Second Affiliated Hospital of Nanchang University (3) · Seoul National University Hospital (3) · Tongji Hospital (3) · Second Affiliated Hospital of Wenzhou Medical University (2) · University Hospital of Split (2) · Ajou University School of Medicine (1) · Beijing Chao Yang Hospital (1) · Chungbuk National University Hospital (1) · DongGuk University (1) · First Affiliated Hospital of Zhejiang University (1) · Gangnam Severance Hospital (1) · Keith M Vogt (1)
South Korea (19) · China (16) · Croatia (2) · Taiwan (1) · United States (1)
Aihua Du, Dr (1) · Ailin Luo (1) · Filip Peris (1) · Gyengjo Byeon, PhD (1) · Ha-Jung Kim (1) · Hee Young Kim, MD, PhD (1) · Hee Young Kim, MD. PhD (1) · Hee-Soo Kim, MD,PhD (1) · Huacheng Liu (1) · Huacheng Liu, Ph.D. (1) · Keith M Vogt, MD, PhD (1) · Li Yi-Shiuan, Bachelor's (1) · Na Li NaLi, MD (1) · Qiaoqiao Xu (1) · Sang-Hwan Do (1)
PMID 10960198, PMID 19953723, PMID 21447488, PMID 23388507, PMID 23512191, PMID 24165817, PMID 24427550, PMID 24442817, PMID 25907462, PMID 25929547, PMID 26756765, PMID 27111535, PMID 27544232, PMID 27792044, PMID 28654138, PMID 28973220, PMID 29210033, PMID 29687891, PMID 29723512, PMID 30236233, PMID 30292760, PMID 30998509, PMID 31729018, PMID 31794513, PMID 31802534, PMID 31939844, PMID 32303884, PMID 32417976, PMID 32677707, PMID 33555690, PMID 34859868, PMID 34916051, PMID 37993525, PMID 38378937, PMID 38609684, PMID 38760702, PMID 3924084, PMID 40514628, PMID 41892844, PMID 42182779
R35GM146822 (1)