7 unknown, 6 completed, 5 recruiting, 2 not yet recruiting. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Unknown 7, Completed 6, Recruiting 5, Not yet recruiting 2, Enrolling by invitation 1 |
Follow Remimazolam: new trials by email Literature Review of Remimazolam trials Research Report on Remimazolam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient-controlled Remimazolam Sedation Under Spinal Anesthesia Patient-controlled sedation, Clinician-controlled sedation - Hip Arthroplasty, Spinal Anesthesia | Not applicable | Recruiting | Seoul National University Hospital | 104 | 2026-10-26 | 2026-11-03 |
| Remimazolam on the Incidence of Postoperative Acute Kidney Injury Remimazolam (Byfavo), propofol - Remimazolam, Propofol | Not applicable | Not yet recruiting | Seoul National University Bundang Hospital | 78 | 2026-06-26 | 2026-06-29 |
| Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation remimazolam group, dexmedetomidine group, esketamine group - Remimazolam, Dexmedetomidine | Not applicable | Recruiting | Maternal and Child Health Hospital of Hubei Province | 150 | 2025-04-01 | 2025-07-10 |
| The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function Remimazolam, propofol - Cognitive Functioning, Propofol | Not applicable | Not yet recruiting | The Second Affiliated Hospital of Chongqing Medical University | 174 | 2025-02-24 | 2025-02-14 |
| Remimazolam Besylate in Sedation of Postcardioperative Patients Remimazolam, Propofol - Remimazolam, Propofol | Not applicable | Recruiting | First Affiliated Hospital of Zhejiang University | 120 | 2025-02-10 | 2025-02-18 |
| RCT Comparing Remimazolam With Propofol Under EEG DSA Guidance During Cardiac Electrophysiology Studies and Ablation Propofol, Remimazolam, With intubation and controlled ventilation to maintain airway - Hemodynamic, Remimazolam | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 200 | 2024-09-20 | 2024-11-22 |
| Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam Flumazenil, normal saline - Flumazenil Adverse Reaction, Remimazolam | Not applicable | Recruiting | Pusan National University Yangsan Hospital | 24 | 2023-09-19 | 2025-09-12 |
| The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia Remimazolam, Dexmedetomidine - Remimazolam, Spinal Anesthesia | Not applicable | Unknown | Pusan National University Yangsan Hospital | 72 | 2023-08-01 | 2023-08-08 |
| The Dose Range of Remimazolam Besylate in Different Age Groups Remimazolam besylate, Propofol - Remimazolam, Anesthesia | Not applicable | Unknown | Tongji Hospital | 1876 | 2023-07-17 | 2023-09-06 |
| Comparison of Hemodynamic Stability During Anesthesia Using Remimazolam and Sevoflurane in Minimally Invasive AVR Remimazolam besylate, Propofol/ Sevoflurane - Aortic Valve Stenosis, Remimazolam | Not applicable | Completed | Pusan National University Yangsan Hospital | 64 | 2023-06-29 | 2025-08-01 |
| Effect of Sevoflurane and Remimazolam on Arterial Oxygenation During One-lung Ventilation Remimazolam, 1% propofol - One-Lung Ventilation, Thoracic Surgery, Video-Assisted | Not applicable | Completed | Pusan National University Yangsan Hospital | 66 | 2023-06-29 | 2024-08-12 |
| Compatible Effect of Remimazolam Besylate Combined With Afentanil for ATI Dos of Afentanil 20, Dos of Afentanil 30, Dos of Afentanil 40 - Remimazolam, Awake Endotracheal Intubation | Not applicable | Unknown | Tongji Hospital | 180 | 2023-04-01 | 2023-09-07 |
| Remimazolam for Postoperative Atrial Fibrillation Remimazolam, midazolam - Coronary Artery Bypass Grafting, Remimazolam | Not applicable | Recruiting | Yangzhou University | 50 | 2023-02-01 | 2023-06-06 |
| Differential Effects of Remimazolam and Propofol on Dynamic Cerebral Autoregulation During General Anesthesia Remimazolam, Propofol - General Anesthesia, Laparoscopic Cholecystectomy | Not applicable | Unknown | Second Affiliated Hospital of Nanchang University | 50 | 2022-10-01 | 2022-09-29 |
| Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol Remimazolam, Propofol - General Anesthesia, Electroencephalography | Not applicable | Unknown | Second Affiliated Hospital of Nanchang University | 12 | 2022-10-01 | 2022-09-29 |
| Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery Remimazolam, Sevoflurane, Fentanyl - Emergence Agitation, Remimazolam | Not applicable | Completed | Second Affiliated Hospital of Nanchang University | 110 | 2022-08-23 | 2023-03-24 |
| Reversal of Remimazolam by a Single Dose of Flumazenil Flumazenil - Flumazenil Adverse Reaction, Ambulatory Surgery | Not applicable | Completed | Konkuk University Medical Center | 224 | 2022-08-02 | 2023-05-19 |
| The Effect of Remifentanil on ED95 of Remimazolam for Loss of Consciousness in Adult Patients Remimazolam, remifantanil - Remimazolam | Not applicable | Unknown | Ajou University School of Medicine | 80 | 2022-07-01 | 2022-06-28 |
| Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance remimazolam group, propofol group - Knee Osteoarthritis, Total Knee Arthroplasty | Not applicable | Completed | Gangnam Severance Hospital | 84 | 2022-06-02 | 2023-07-19 |
| Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy Remimazolam Injection, Propofol Injection - Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication | Not applicable | Unknown | The Third Xiangya Hospital of Central South University | 264 | 2021-08-01 | 2022-06-29 |
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Acute Kidney Injury (1) · Aortic Valve Stenosis (1) · Coronary Artery Disease (1) · Emergence Delirium (1) · Myocardial Infarction (1) · Myocardial Ischemia (1) · Osteoarthritis, Knee (1) · Postoperative Nausea and Vomiting (1)
Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Cardiovascular Diseases (2) · Heart Diseases (2) · Postoperative Complications (2) · Signs and Symptoms (2) · Aortic Valve Disease (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Arthritis (1) · Confusion (1) · Coronary Disease (1) · Delirium (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1)
remimazolam (13) · Propofol (10) · cisatracurium (3) · Dexmedetomidine (2) · Flumazenil (2) · Long-Term Synaptic Depression (2) · Sevoflurane (2) · Sufentanil (2) · Esketamine (1) · Fentanyl (1) · Intubation (1) · Midazolam (1) · Remifentanil (1) · Saline Solution (1)
Pusan National University Yangsan Hospital (4) · Second Affiliated Hospital of Nanchang University (3) · Tongji Hospital (2) · Ajou University School of Medicine (1) · First Affiliated Hospital of Zhejiang University (1) · Gangnam Severance Hospital (1) · Konkuk University Medical Center (1) · Maternal and Child Health Hospital of Hubei Province (1) · Peking University People's Hospital (1) · Seoul National University Bundang Hospital (1) · Seoul National University Hospital (1) · Taipei Veterans General Hospital, Taiwan (1) · The Second Affiliated Hospital of Chongqing Medical University (1) · The Third Xiangya Hospital of Central South University (1) · Yangzhou University (1)
China (11) · South Korea (7) · Taiwan (1)
Ailin Luo (1) · Gyengjo Byeon, PhD (1) · Hee Young Kim, MD, PhD (1) · Hee Young Kim, MD. PhD (1) · Li Yi-Shiuan, Bachelor's (1) · Na Li NaLi, MD (1) · Qiaoqiao Xu (1) · Sangwook Shin, MD. PhD (1) · Seong-Hyop Kim, M.D. Ph.D (1) · Xiaoyan Wang, Doctor (1)
PMID 10960198, PMID 19953723, PMID 21447488, PMID 23388507, PMID 23512191, PMID 24165817, PMID 24427550, PMID 24442817, PMID 25907462, PMID 25929547, PMID 26756765, PMID 27111535, PMID 27544232, PMID 27792044, PMID 28654138, PMID 28973220, PMID 29210033, PMID 29687891, PMID 29723512, PMID 30236233, PMID 30292760, PMID 30998509, PMID 31729018, PMID 31794513, PMID 31802534, PMID 31939844, PMID 32303884, PMID 32417976, PMID 32677707, PMID 33555690, PMID 34859868, PMID 34916051, PMID 3924084, PMID 42182779