51 completed, 19 unknown, 5 recruiting, 4 not yet recruiting. 30 Not applicable, 15 Phase 2, 13 Phase 1, 12 Phase 3, 12 Phase 4.
Follow Long-Term Synaptic Depression: new trials by email Literature Review of Long-Term Synaptic Depression trials Research Report on Long-Term Synaptic Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zuberitamab in the First Episode of Paediatric Nephrotic Syndrome Zuberitamab, standard corticosteroid treatment - Nephrotic Syndrome | Phase 3 | Not yet recruiting | Children's Hospital of Fudan University | 120 | 2026-08-20 | 2026-08-14 |
| Perfluorohexyloctane Eye Drops vs. Sodium Hyaluronate for Video Display Terminal-Associated Dry Eye 0.1% Sodium Hyaluronate Eye Drops, Perfluorohexyloctane Eye Drops (PFHO) - Dry Eye | Phase 4 | Not yet recruiting | Beijing Tongren Hospital | 159 | 2026-06-30 | 2026-07-01 |
| Bovis Calculus Stativus Treat Acute Cerebral Ischemic Stroke With Impaired Consciousness Bovis Calculus Stativus (BCS), Placebo - Acute Ischemic Stroke AIS, Impaired Consciousness | Phase 2 / Phase 3 | Not yet recruiting | Xiang Luo | 220 | 2025-12-15 | 2025-12-18 |
| Identification of HER2-Positive Breast Cancer Molecular Characterization and Subtypes Trastuzumab, Pertuzumab, Chemotherapy - Breast Cancer | Not applicable | Not yet recruiting | Shandong Cancer Hospital and Institute | 1039 | 2025-09-30 | 2025-09-23 |
| Human Bioequivalence Study of Liposomal Amphotericin B for Injection Test product (Liposomal amphotericin B for injection, Sichuan Huiyu Pharmaceutical Co., Ltd.), Reference product (AmBisome®, Astellas Pharma US Inc.) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 58 | 2025-05-25 | 2026-05-27 |
| Human Bioequivalence Study of Amphotericin B Liposome for Injection Amphotericin B Liposome for Injection (strength: 50 mg, Sichuan Huiyu Pharmaceutical Co., Ltd.), Amphotericin B Liposome for Injection (trade name: Ambisome®, strength: 50 mg, MAH: Gilead Sciences) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 42 | 2025-05-13 | 2026-05-22 |
| Study Evaluating PEG-G-CSF Injectionin Preventing Neutropenia After Chemotherapy PEG-G-CSF injection (Kexing Biopharmaceutical Co., Ltd.), PEG-G-CSF injection (Neulasta®，Amgen Europe B.V.) - Neutropenia, Chemotherapy-Induced Febrile, Breast Neoplasm Female | Phase 3 | Active not recruiting | Kexing Biopharm Co., Ltd. | 250 | 2025-01-09 | 2025-11-25 |
| Bioequivalence Study of Iron Sucrose Injection in Healthy Participants Iron Sucrose injection (Test product, manufactured by Sichuan Huiyu Pharmaceutical Co., Ltd) and Iron Sucrose injection (Reference product, Venofer), Iron Sucrose injection (Reference product, Venofer) and Iron Sucrose injection (Test product, manufactured by Sichuan Huiyu Pharmaceutical Co., Ltd) - Bioequivalency, Safety Issues | Phase 1 | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 48 | 2024-11-22 | 2025-03-24 |
| Evidence-based Evaluation and Mechanism of Shenhuang Granules in the Treatment of Sepsis shenhuang granule, placebo - Sepsis | Early Phase 1 | Recruiting | The First Affiliated Hospital of Zhejiang Chinese Medical University | 410 | 2024-07-01 | 2025-08-22 |
| Bioequivalence Study of Iron Sucrose Injection in Healthy Subjects Iron Sucrose injection (Test product, manufactured by Sichuan Huiyu Pharmaceutical Co., Ltd) and Iron Sucrose injection (Reference product, Venofer), Iron Sucrose injection (Reference product, Venofer) and Iron Sucrose injection (Test product, manufactured by Sichuan Huiyu Pharmaceutical Co., Ltd) - Bioequivalency, Safety Issues | Phase 1 | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 48 | 2024-06-25 | 2024-10-08 |
| Tirofiban After Successful MT Recanalization in AIS Tirofiban, Saline placebo - Acute Ischemic Stroke, Vessel Occlusion | Phase 2 / Phase 3 | Completed | Xiang Luo | 1380 | 2024-04-09 | 2026-03-11 |
| The Effectiveness of Vitamin D Supplementation in Patients With End-stage Knee Osteoarthritis Vitamin D, Placebo - Vitamin D Deficiency, Sarcopenia | Not applicable | Unknown | Chinese University of Hong Kong | 56 | 2024-03-17 | 2024-03-27 |
| XCHT for Irinotecan-Induced Gut Toxicities (Randomized Controlled Trial) Xiao Chai Hu Tang (XCHT), Placebo, Irinotecan regimen - Xiao Chai Hu Tang, Irinotecan-induced Diarrhea | Not applicable | Recruiting | Guangzhou University of Traditional Chinese Medicine | 98 | 2024-03-08 | 2025-07-01 |
| Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS) Human urinary kininogenase(HUK), Placebo - Acute Ischemic Stroke | Not applicable | Recruiting | First Affiliated Hospital of Harbin Medical University | 200 | 2024-01-01 | 2024-11-20 |
| Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients Rivaroxaban 10 MG, Placebo - Glioma, Malignant | Not applicable | Unknown | Nanfang Hospital, Southern Medical University | 320 | 2023-11-01 | 2024-01-09 |
| Cyclopofol Versus Propofol for Postoperative Delirium in Elderly Patients Having Orthopedic Surgery Cyclopofol, Propofol - Postoperative Delirium, Stroke | Phase 4 | Unknown | RenJi Hospital | 60 | 2023-10-01 | 2023-09-21 |
| Study on the Bioequivalence of Amisulpride Orally Disintegrating Tablets in Human Body Drug: Test (T) Amisulpride orally disintegrating tablets (200mg). Produced and supplied by Zezheng (Shanghai) Biotechnology Co., Ltd. - Bioequivalence, Schizophrenia | Phase 1 | Unknown | The Affiliated Hospital of Qingdao University | 100 | 2023-09-20 | 2023-10-04 |
| Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam Flumazenil, normal saline - Flumazenil Adverse Reaction, Remimazolam | Not applicable | Recruiting | Pusan National University Yangsan Hospital | 24 | 2023-09-19 | 2025-09-12 |
| Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in Allergic Rhinitis High-intensity focused ultrasound (HIFU), intranasal corticosteroids, oral antihistamines, oral leukotriene receptor antagonists, and intranasal antihistamines - Allergic Rhinitis | Early Phase 1 | Unknown | Chongqing Medical University | 240 | 2023-08-01 | 2024-02-22 |
| Safety, Tolerability and Pharmacokinetics of Meloxicam Nanocrystal Injection in Healthy Subjects Meloxicam Nanocrystal Injection(Yangtze River Pharmaceutical Group Co., Ltd.), Meloxicam Nanocrystal Injection (ANJESO®) - Pain | Phase 1 | Completed | Yangtze River Pharmaceutical Group Co., Ltd. | 20 | 2023-07-05 | 2026-06-29 |
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Ischemic Stroke (5) · Bile Duct Neoplasms (3) · Colorectal Neoplasms (2) · Dry Eye Syndromes (2) · Esophageal Neoplasms (2) · Febrile Neutropenia (2) · Hypertension (2) · Invasive Fungal Infections (2) · Leishmaniasis, Visceral (2) · Mumps (2) · Neoplasms (2) · Pain (2) · Pancreatic Neoplasms (2) · Rhinitis, Allergic (2) · Sjogren's Syndrome (2)
Chiba University (4) · Sichuan Huiyu Pharmaceutical Co., Ltd (4) · Seoul National University Hospital (3) · Beijing Tongren Hospital (2) · Guangzhou University of Traditional Chinese Medicine (2) · Jiangsu Province Centers for Disease Control and Prevention (2) · Korea University Anam Hospital (2) · Maastricht University Medical Center (2) · Pusan National University Yangsan Hospital (2) · Xiang Luo (2) · Affiliated Hospital of Jiangnan University (1) · Asan Medical Center (1) · Beijing Minhai Biotechnology Co., Ltd (1) · Bispebjerg Hospital (1) · Centers for Disease Control and Prevention, China (1)
China (42) · South Korea (13) · Japan (4) · Taiwan (4) · Brazil (2) · Netherlands (2) · United States (2) · Denmark (1) · Hong Kong (1) · Pakistan (1) · Russia (1) · Thailand (1) · Turkey (Türkiye) (1)
Katsunori Furukawa, MD (3) · Qing Wen (2) · Annemie Schols, Prof. (1) · Bo Ri Kim, M.D., Ph.D. (1) · Bo Young Chung, M.D., PhD (1) · Brett R Levine, MD (1) · Chang-O Kim, M.D, MSW (1) · Chenjin Jin, Dr. (1) · Chuanling Li (1) · Chun Wan (1) · Daisuke Suzuki (1) · Eunah Cho, M.Dm. (1) · Feng DanDan, master (1) · Fernando V Andrigueti, MD (1)
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