517 completed, 173 unknown, 93 recruiting, 41 terminated. 487 Not applicable, 57 Phase 4, 31 Phase 2, 30 Phase 3, 16 Phase 1.
Follow Obesity, Morbid: new trials by email Literature Review of Obesity, Morbid trials Research Report on Obesity, Morbid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Study of an Explainable AI Tool to Support Biliopancreatic Limb Selection in One-Anastomosis Gastric Bypass One-anastomosis gastric bypass with observed biliopancreatic limb length - Obesity, Severe Obesity | Not yet recruiting | The Society of Bariatric and Metabolic Surgeons of Kazakhstan | 120 | 2027-01-15 | 2026-09-14 | |
| Tapered Versus Abrupt Discontinuation of Semaglutide After Treatment of Recurrent Weight Gain or Suboptimal Response Following Metabolic and Bariatric Surgery Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight Gain Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Semaglutide Before Primary Metabolic and Bariatric Surgery in Patients With BMI 60 kg/m² or Higher Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Evaluating Metabolic Health in Individuals With Extreme Obesity High-fat test meal - BMI>40 | Not yet recruiting | Pennington Biomedical Research Center | 10 | 2026-10-01 | 2026-09-17 | |
| Inhaled Nitric Oxide in Severe Obesity Nitric oxide - Obesity, Respiratory Insufficiency | Not applicable | Not yet recruiting | Massachusetts General Hospital | 60 | 2026-10-01 | 2026-05-20 |
| Semaglutide 2.4 mg Once Weekly for Recurrent Weight Gain After Metabolic and Bariatric Surgery (RESURGE) Semaglutide weekly injection, Placabo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 104 | 2026-10-01 | 2026-10-05 |
| Immediate Versus Criterion-triggered Semaglutide for Suboptimal Clinical Response One Year After Primary Metabolic and Bariatric Surgery Semaglutide weekly injection, Placebo - Morbid Obesity | Phase 4 | Not yet recruiting | General Committee of Teaching Hospitals and Institutes, Egypt | 100 | 2026-10-01 | 2026-10-05 |
| Continuous Glucose Monitoring in Metabolic Surgery Abbot Freestyle Libre CGM - Obesity (Disorder) | Not applicable | Not yet recruiting | Pennington Biomedical Research Center | 20 | 2026-09-20 | 2026-09-15 |
| Investigating Metabolic, Brain, and Cognitive Alterations Through Bariatric Surgery Sleeve Gastrectomy - Obesity, Morbid | Not yet recruiting | Laval University | 150 | 2026-09-01 | 2026-07-16 | |
| Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt - Obesity, Obesity, Morbid | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 10 | 2026-09-01 | 2025-12-02 |
| Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH) Prophylactic mesh - Abdominal Aortic Aneurysm, Morbid Obesity | Not yet recruiting | Aesculap AG | 110 | 2026-09-01 | 2026-06-02 | |
| Impact of MBS on Body Composition, Basal Metabolic Rates and Muscle Functions in Morbid Obese Patients Obesity, Morbid, Obesity; Endocrine | Not yet recruiting | All India Institute of Medical Sciences, Bhubaneswar | 21 | 2026-09-01 | 2026-07-30 | |
| Videolaryngoscopes in the Morbidly Obese Airway management - Obesity Difficult Airway Airway Management | Not applicable | Enrolling by invitation | Uniwersytet Radomski im. Kazimierza Pułaskiego | 100 | 2026-08-15 | 2026-08-26 |
| GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity GLP-1 receptor agonist therapy - Morbid Obesity, Anorectal Diseases | Not yet recruiting | Gazi University | 100 | 2026-08-01 | 2026-06-25 | |
| Glycemic Variability After SASI Versus Roux-en-Y Gastric Bypass Single Anastomosis Sleeve Ileal Bypass, Roux-en-Y Gastric Bypass - Obesity, Morbid | Not applicable | Recruiting | Hospitales Universitarios Virgen del Rocío | 68 | 2026-07-14 | 2026-10-13 |
| Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management Clinical and Biochemical Assessment - Obesity, Morbid, Bariatric Surgery | Not yet recruiting | Toros University | 40 | 2026-07-01 | 2026-06-11 | |
| Impact of Bariatric Surgery on Female Sexual Function and Sex Hormones Sleeve Gastrectomy, Gastric Bypass - Morbid Obesity | Recruiting | Cairo University | 40 | 2026-06-05 | 2026-06-10 | |
| Investigation of the Effects of Whole Body Vibration Application on Muscle Functional Level, Physical Fitness and Respiratory Parameters After Bariatric Surgery Resistance Training, Whole Body Vibration, Control Group - Obesity & Overweight, Morbid Obesity | Not applicable | Not yet recruiting | Kirsehir Ahi Evran Universitesi | 60 | 2026-05-30 | 2026-05-22 |
| High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea High-Intensity Progressive Inspiratory Muscle Training (IMT) - Obesity, Class III, Sleep Apnea, Obstructive | Not applicable | Not yet recruiting | University of the State of Santa Catarina | 10 | 2026-05-01 | 2026-03-23 |
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Obesity (258) · Weight Loss (82) · Diabetes Mellitus, Type 2 (39) · Metabolic Syndrome (33) · Diabetes Mellitus (27) · Non-alcoholic Fatty Liver Disease (26) · Motor Activity (24) · Insulin Resistance (23) · Gastroesophageal Reflux (22) · Hypertension (19) · Pain, Postoperative (19) · Overweight (17) · Postoperative Complications (13) · Sleep Apnea, Obstructive (13)
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Bariatric Surgery (55) · Gastric Bypass (50) · Acetaminophen (8) · Exercise (8) · Surgical Procedures, Operative (8) · Propofol (7) · Saline Solution (7) · Control Groups (6) · Diet (6) · Liraglutide (6) · Fentanyl (5) · Ketamine (5) · Surveys and Questionnaires (5) · Bupivacaine (4) · Caloric Restriction (4)
Norwegian University of Science and Technology (33) · Minia University (18) · Mansoura University (17) · Assistance Publique - Hôpitaux de Paris (13) · Rijnstate Hospital (11) · IHU Strasbourg (10) · Hvidovre University Hospital (9) · Inonu University (9) · Laval University (9) · Ain Shams University (8) · Fatih Sultan Mehmet Training and Research Hospital (8) · University of Foggia (8) · General Committee of Teaching Hospitals and Institutes, Egypt (7) · Johns Hopkins University (7) · Sheba Medical Center (7)
United States (210) · Egypt (73) · Turkey (Türkiye) (70) · France (64) · Italy (54) · Norway (51) · Brazil (37) · Spain (37) · Canada (32) · Netherlands (31) · Israel (23) · Germany (20) · Sweden (16) · Switzerland (15) · Denmark (12)
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