23 completed, 12 unknown, 5 recruiting, 3 withdrawn. 13 Phase 4, 12 Not applicable, 8 Phase 2, 4 Phase 1, 3 Phase 3.
Follow Procedural Sedation: new trials by email Literature Review of Procedural Sedation trials Research Report on Procedural Sedation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department. Ketamine (1 mg/kg), propofol, Dexmedetomidine - Procedural Sedation | Phase 4 | Not yet recruiting | Sultan Qaboos University | 100 | 2026-10-10 | 2026-10-15 |
| Therapeutic Effects of Music on Procedural Outcomes Low-Tempo Instrumental Music, Silent Audio Control - Procedural Sedation, Gastrointestinal Endoscopy | Not applicable | Recruiting | Bahaa Bou Dargham | 180 | 2026-08-01 | 2026-08-13 |
| SED Pack: Safety and Performance of a Medical Device Software for Predictive Monitoring During Sedation Procedural Sedation, Gastrointestinal Endoscopy | Recruiting | Predictheon Medical, S.L. | 120 | 2026-07-23 | 2026-08-06 | |
| Personalized Music, Dreaming During Propofol Sedation Preferred Music, Matched Non-preferred Music, Silence Control - Procedural Sedation, Dreams | Not applicable | Completed | Wonkwang University Hospital | 300 | 2026-06-24 | 2026-08-14 |
| HFNO Versus Face Mask for Cerebral Oxygenation During Procedural Sedation High-Flow Nasal Oxygen (HFNO), Conventional Face Mask Oxygen - Procedural Sedation, Hypoxemia | Not applicable | Recruiting | Firat University | 100 | 2026-06-01 | 2026-07-21 |
| Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2 General Anesthesia, Procedural sedation - Ischemic Stroke, Anterior Cerebral Circulation | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 958 | 2026-03-24 | 2026-09-02 |
| Ketodex Versus Ketofol in Adolescent Gastrointestinal Endoscopy Ketodex, Ketofol - Procedural Sedation, Gastrointestinal Endoscopy | Completed | Giresun University | 90 | 2026-02-02 | 2026-08-06 | |
| Propofol vs Remifentanil for Sedation in Gastroscopy Propofol (Astra-Zeneca), Remifentanil - Conscious Sedation, Procedural Sedation | Not applicable | Completed | Fatih Sultan Mehmet Training and Research Hospital | 80 | 2026-02-02 | 2026-04-21 |
| Remimazolam vs Propofol in Laser Burn Cases Remimazolam besylate, Propofol - Burn Scar, Hypertrophic Scarring | Phase 4 | Recruiting | Medical University of South Carolina | 136 | 2025-11-12 | 2025-11-20 |
| Effect of Discontinuing Propofol After Cecal Intubation on Patient's Psychomotor Recovery Following Colonoscopy propofol (drug) - Procedural Sedation, Colonoscopy | Not applicable | Active not recruiting | American University of Beirut Medical Center | 100 | 2025-05-19 | 2025-09-11 |
| Remimazolam-Propofol Combination Sedation for Gastrointestinal Endoscopy: A Prospective Observational Study Procedural Sedation, Gastrointestinal Endoscopy | Completed | University of Medicine and Pharmacy "Victor Babes" Timisoara | 29 | 2024-11-01 | 2026-05-22 | |
| The Efficacy of Laryngeal Mask Airway Gastro (LMA® Gastro™) in Preventing Hypercarbia in ERCP Patients LMA Gastro - Endoscopy, Gastrointestinal, Procedural Sedation | Not applicable | Completed | Cairo University | 50 | 2024-10-01 | 2025-09-19 |
| The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study Precedex (Dexmedetomidine) 200 MCG in 2 ML Injection, C group: Patients received saline infusion over 10 minutes - GIT Endoscopy, Procedural Sedation | Phase 4 | Unknown | Theodor Bilharz Research Institute | 52 | 2024-05-01 | 2024-05-16 |
| Propofol Infusion-Based Sedation on Anesthesia-Related Adverse Events in Endoscopic Ultrasonography Procedural Sedation - Sedation Complication, Endoscopic Ultrasonography | Completed | Samsun University | 75 | 2024-04-24 | 2024-08-09 | |
| Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting ketamine- midazolam versus ketamine- propofol - Procedural Sedation | Early Phase 1 | Unknown | Alexandria University | 50 | 2024-04-01 | 2024-04-16 |
| Factors Associated With Successful Completion of MRI in Children Undergoing a Vigil Sedation With Dexmedetomidin Data collection of successful completion of MRI - Procedural Sedation, EEG | Completed | Centre Hospitalier Régional Metz-Thionville | 81 | 2024-01-01 | 2024-08-09 | |
| INK Feasibility Study Intranasal ketamine - Procedural Sedation | Phase 3 | Withdrawn | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2024-01-01 | 2023-03-24 | |
| Effects of Sedation Agents on Optic Nerve Sheath Diameter Procedural Sedation | Completed | Alanya Alaaddin Keykubat University | 73 | 2023-11-01 | 2026-10-20 | |
| Electroencephalogram Based Real-Time Sedation Level Prediction Propofol, Remifentanil - Procedural Sedation | Unknown | University Medical Center Groningen | 1000 | 2023-03-01 | 2023-03-13 | |
| EEG Spectral Pattern of Deep Sedation-induced Airway Adverse Effects Airmod breathing sound monitoring - Procedural Sedation | Unknown | National Taiwan University Hospital | 60 | 2022-11-01 | 2022-11-04 |
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Emergencies (5) · Hypercapnia (2) · Hypoxia (2) · Agnosia (1) · Apnea (1) · Arteriovenous Fistula (1) · Brain Injuries, Traumatic (1) · Bunion (1) · Cicatrix, Hypertrophic (1) · Dilatation, Pathologic (1) · Emergence Delirium (1) · Ischemic Stroke (1) · Learning Disabilities (1) · Mental Disorders (1) · Pain (1)
Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (7) · Signs and Symptoms (7) · Disease Attributes (5) · Nervous System Diseases (5) · Neurologic Manifestations (4) · Neurobehavioral Manifestations (3) · Signs and Symptoms, Respiratory (3) · Brain Diseases (2) · Cardiovascular Diseases (2) · Central Nervous System Diseases (2) · Mental Disorders (2) · Respiration Disorders (2) · Respiratory Tract Diseases (2) · Vascular Diseases (2)
Propofol (11) · Midazolam (9) · Dexmedetomidine (7) · Ketamine (5) · Injections (3) · Chloral Hydrate (2) · Remifentanil (2) · fospropofol (2) · remimazolam (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Alfentanil (1) · Anesthesia, General (1) · Fentanyl (1) · Pharmaceutical Preparations (1) · Saline Solution (1)
Paion UK Ltd. (2) · Zagazig University (2) · Ain Shams University (1) · Alanya Alaaddin Keykubat University (1) · Albert Einstein Healthcare Network (1) · Alexandria University (1) · American University of Beirut Medical Center (1) · Atlantic Center for Oral and Maxillofacial Surgery (1) · Azienda Ospedaliera di Padova (1) · Bahaa Bou Dargham (1) · Cairo University (1) · Centre Hospitalier Régional Metz-Thionville (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Eisai Inc. (1) · Fatih Sultan Mehmet Training and Research Hospital (1)
United States (10) · Egypt (6) · Turkey (Türkiye) (5) · Canada (2) · France (2) · Israel (2) · Lebanon (2) · Spain (2) · Brazil (1) · China (1) · Finland (1) · Iran (1) · Italy (1) · Oman (1) · Romania (1)
Alshaimaa Kamel, M.D (1) · Ashraf Fathy Elshehry, FRCEM-UK (1) · Ayat A Hassan, MD (1) · Bahaa W Bou Dargham, MD (1) · Ben Davis, DDS FRCD(C) (1) · Caner Genc, M.D. (1) · Cheol Lee, M.D.,Ph.D (1) · Chun-Yu Wu (1) · Eduardo Mekitarian Filho, MSc (1) · Franck Verschuren, MD, PhD (1) · Ghada M Bashandy, MD (1) · James B Jones, MD, PharmD (1) · James R Miner, MD (1)
PMID 12826556, PMID 15505441, PMID 16238552, PMID 16946280, PMID 18072987, PMID 19589455, PMID 19845550, PMID 20857254, PMID 22536619, PMID 22615015, PMID 25145661, PMID 25441247, PMID 25502841, PMID 27354454, PMID 27516413, PMID 28557732