Alfentanil: Clinical Trials

48 trials of Alfentanil, newest first

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38 completed, 4 unknown, 3 not yet recruiting, 2 recruiting. 20 Phase 4, 19 Not applicable, 2 Phase 1, 2 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 420Completed 15, Not yet recruiting 2, Recruiting 1, Unknown 1, Withdrawn 1
Not applicable19Completed 16, Unknown 2, Recruiting 1
Phase 12Completed 1, Not yet recruiting 1
Phase 32Completed 2

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Afentanil and Remifentanil for Anesthesia Quality and Recovery
alfentanil, Remifentanil - Anesthesia Recovery Period ; Postoperative Pain; Hemodynamic Stability During Surgery
Phase 4Not yet recruitingQianfoshan Hospital9902026-09-012026-08-12
A Study to Evaluate the Drug-Drug Interaction Between KL0011034 Injection and Alfentanil Hydrochloride Injection in Participants With Moderate-to-Severe Non-Cancer Chronic Pain
KL0011034 injection, Alfentanil Hydrochloride Injection - Chronic Pain
Phase 1Not yet recruitingThe Third Xiangya Hospital of Central South University272026-07-302026-08-07
A Study Evaluating the Drug-Drug Interaction Between KL0011034 Injection and Alfentanil Hydrochloride Injection
KL0011034 injection, Alfentanil Hydrochloride Injection - Chronic Pain
Phase 1CompletedHunan Kelun Pharmaceutical Co., Ltd.272026-07-152026-09-17
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
Alfentanil - Pediatric Anesthesia, Airway Management
Phase 4CompletedZhongshan Ophthalmic Center, Sun Yat-sen University232026-05-202026-10-07
A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined With Alfentanil for Anesthesia in Thoracic Surgery
Remimazolam Besylate for Injection, Propofol, Alfentanil Hydrochloride Injection - Thoracic Surgery, Anesthesia
Phase 4Not yet recruitingThe First Affiliated Hospital of Xinxiang Medical College502026-03-012026-01-16
Remimazolam for Bronchoscopy in High-Risk Patients
propofol and alfentanil, remimazolam combined with propofol and alfentanil - Pulmonary Infection, Pulmonary Nodule
Phase 4RecruitingFirst Affiliated Hospital of Zhejiang University3602026-02-092026-02-24
EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives
high dose of alfentanil, low dose of alfentanil with propofol - Sedation and Analgesia, Cholangiopancreatography, Endoscopic Retrograde
Not applicableRecruitingChi Kwan Fung202025-10-102026-03-27
Low-dose Propofol Plus High-dose Alfentanil in Rapid Sequence Induction
propofol, alfentanil, Sufentanil - Hemodynamic Instability During Anesthesia, Induction Anesthesia
Not applicableCompletedAoyang Hospital Affiliated to Jiangsu University1722025-08-012026-07-28
To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery
Alfentanil - Procedural Pain
Phase 4UnknownKaohsiung Medical University Chung-Ho Memorial Hospital402024-08-132024-08-20
Effect of Equivalent Dose of Alfentanil and Sufentanil in Bronchoscopic Treatment
Alfentanil - Effect of Drug
Not applicableCompletedTongji Hospital802024-05-202025-01-14
Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?
Alfentanil, Oxycodone - Hip Injuries, Hip Fractures
CompletedNHS Lothian642024-03-042024-12-06
Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement
ciprofol, propofol - Hemodynamics, Transcatheter Aortic Valve Replacement
Phase 4CompletedSecond Affiliated Hospital, Zhejiang University, School of Medicine1242023-06-292026-01-15
Patient-Controlled Sedation in Port Implantation (PACSPI-2)
Propofol + Alfentanil - Pain, Patient Satisfaction
Phase 4CompletedRegion Jönköping County3402023-01-192024-11-12
Observational Study on the Incorporation of Opioids and Their Metabolites Into Hair of Pediatric Patients
Fentanyl - Opioid Use, Unspecified
CompletedUniversity of Zurich1502022-12-062025-03-30
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia
Bispectral index (BIS) or Patient State Index (PSI), Propofol, Alfentanil - Anesthesia, Drug Interaction
UnknownTaipei Veterans General Hospital, Taiwan602022-10-012022-09-07
Comparison of Postoperative Pain Application of Alfentanil or Remifentanil in TIVA
Propofol combined with alfentanil, Propofol combined with remifentanil - Postoperative Pain
Phase 4CompletedXijing Hospital1302022-04-292023-01-19
Modeling and Application of Triple Drug Response Surface Models
Fentanyl, Bispectral index (BIS) and analgesia nociception index (ANI), alfentanil - Pharmacodynamics, Drug Interactions
CompletedTaipei Veterans General Hospital, Taiwan1002019-06-122022-07-20
Pre-medication With Alfentanil vs Placebo During ECT
Alfentanil, Placebos - Blood Pressure, Electroconvulsive Therapy
Phase 4CompletedWake Forest University Health Sciences1002018-06-042021-07-08
Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis
Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email - Postoperative Nausea and Vomiting
Not applicableCompletedVanderbilt University270342016-07-012019-03-07
Effect of a Bolus of 10 µg/kg of Alfentanil on the Pupillary Pain Index
Alfentanil, sevoflurane or propofol - Pain, Anesthesia
Not applicableCompletedPr Isabelle CONSTANT142016-04-012017-05-03

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Conditions studied

Pain (8)  ·  Agnosia (2)  ·  Chronic Pain (2)  ·  Hypoxia (2)  ·  Lung Diseases (2)  ·  Neoplasms (2)  ·  Pain, Postoperative (2)  ·  Adenoviridae Infections (1)  ·  Anxiety Disorders (1)  ·  Arrhythmias, Cardiac (1)  ·  Autistic Disorder (1)  ·  Biliary Tract Diseases (1)  ·  Bipolar Disorder (1)  ·  Bradycardia (1)  ·  Brain Ischemia (1)

Sponsors

Hennepin Healthcare Research Institute (2)  ·  Martin Angst (2)  ·  Rabin Medical Center (2)  ·  Taipei Veterans General Hospital, Taiwan (2)  ·  Aoyang Hospital Affiliated to Jiangsu University (1)  ·  Chang Gung Memorial Hospital (1)  ·  Chi Kwan Fung (1)  ·  Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1)  ·  Daniel Benjamin (1)  ·  First Affiliated Hospital of Zhejiang University (1)  ·  Gachon University Gil Medical Center (1)  ·  Gloucestershire Hospitals NHS Foundation Trust (1)  ·  Hadassah Medical Organization (1)  ·  Hallym University Medical Center (1)  ·  Helsinki University Central Hospital (1)

Countries

United States (9)  ·  China (7)  ·  Taiwan (5)  ·  Israel (4)  ·  United Kingdom (3)  ·  France (2)  ·  Sweden (2)  ·  Turkey (Türkiye) (2)  ·  Belgium (1)  ·  Brazil (1)  ·  Canada (1)  ·  Finland (1)  ·  Germany (1)  ·  Lebanon (1)  ·  Malaysia (1)

Top investigators

Martin S Angst (2)  ·  Andre GS Leite, PhD (1)  ·  Chi Hornik, PharmD (1)  ·  Chi Kwan Boris Fung, MD (1)  ·  Chi-Ming Poon, MBBS (1)  ·  Chung Hsing Hsieh, M.D. (1)  ·  David A Tompkins, M.D. (1)  ·  Evan D Kharasch, MD, PhD (1)  ·  Florian Zapf, Dr. (1)  ·  Franck Verschuren, MD, PhD (1)  ·  Frank Dumortier, MD (1)  ·  Harri Mustonen, DSc (1)  ·  Hyun Jeong Kwak, MD.PhD (1)  ·  Isabelle Constant, PHD (1)

Results publications

PMID 10735670, PMID 11506101, PMID 16211735, PMID 19602953, PMID 2245677, PMID 23446076, PMID 23701339, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26176994, PMID 26926644, PMID 27484339, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29677389, PMID 30198934, PMID 30790601, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33903114, PMID 34302290, PMID 35370711, PMID 35491971, PMID 36215414, PMID 40397427, PMID 41214479, PMID 41247430, PMID 42031608, PMID 42873753, PMID 657853, PMID 8404160, PMID 9560538, PMID 9743396

NIH funding

2009 (1), K24DA023186 (1), R01GM063674 (1)