198 completed, 63 unknown, 61 recruiting, 35 not yet recruiting. 117 Phase 2, 103 Not applicable, 59 Phase 3, 58 Phase 4, 56 Phase 1.
Follow Pharmaceutical Preparations: new trials by email Literature Review of Pharmaceutical Preparations trials Research Report on Pharmaceutical Preparations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Group PACBT for Depression Psilocybin (drug), Group Cognitive Behavioral Therapy - Depression - Major Depressive Disorder, Psilocybin | Phase 2 | Not yet recruiting | University of California, Los Angeles | 30 | 2027-01-01 | 2026-05-04 |
| SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy Spironolactone (drug), Candesartan 8mg, Hydrochlorothiazide (HCTZ) 25 milligrams. - Hypertension | Phase 4 | Not yet recruiting | Ottawa Hospital Research Institute | 30 | 2027-01-01 | 2026-10-14 |
| Effects of Psilocybin on Craving in Nicotine Dependence Psilocybin (drug) - Nicotine Dependence | Phase 2 | Not yet recruiting | University of British Columbia | 3 | 2027-01-01 | 2026-10-01 |
| Efficacy and Safety of Spironolactone in Pediatric Hemodialysis Patients With Anemia. Spironolactone (drug), Iron Supplement, Erythropoietin stimulating agent - Anemia | Phase 2 | Not yet recruiting | Ain Shams University | 40 | 2026-12-01 | 2026-07-20 |
| Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic Stenosis Dapagliflozin (DAPA), Spironolactone (drug), Spironolactone + Dapagliflozin - Aortic Stenosis | Phase 2 | Not yet recruiting | University College, London | 445 | 2026-12-01 | 2026-09-11 |
| Rifaximin Treatment in Bloating Predominant Functional Bowel Disorders Rifaximin (drug), Placebo - Bloating, Rifaximin | Phase 3 | Not yet recruiting | Mahidol University | 78 | 2026-12-01 | 2026-10-27 |
| NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy Psilocybin (drug), Standard of Care (SOC) - Psilocybin, Neuropathy | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 83 | 2026-11-04 | 2026-10-05 |
| SIMBA in Irritable Bowel Syndrome (IBS) Rifaximin (drug), fluid biopsy capsule - Irritable Bowel Syndrome (IBS), Microbiome | Phase 1 | Not yet recruiting | University of Calgary | 180 | 2026-11-01 | 2026-10-20 |
| Pain Control During ESWL Using Non-Opioid Analgesics Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam - Urolithiasis, Kidney Stones | Phase 4 | Not yet recruiting | University of Gaziantep | 160 | 2026-10-01 | 2026-08-12 |
| Comparing Inclisiran Versus Statin for Primary Aldosteronism inclisiran, Lipophilic statins (such as Simvastatin, Atorvastatin, Fluvastatin, Lovastatin,Pitavastatin), Spironolactone (drug) - Primary Aldosteronism | Not applicable | Recruiting | Third Military Medical University | 50 | 2026-10-01 | 2026-10-21 |
| Guishen Yijing Granules for Diminished Ovarian Reserve With Kidney Deficiency Syndrome: A Randomized Controlled Trial Guishen Yijing Granules, Coenzyme Q10 (drug) - Diminished Ovarian Reserve (DOR) | Early Phase 1 | Not yet recruiting | Shi Yun | 120 | 2026-09-22 | 2026-09-25 |
| Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment Lidocaine (drug), Saline - Refractory Migraine, Headache | Phase 2 | Recruiting | Daniel A Tonetti, MD | 80 | 2026-09-09 | 2026-10-01 |
| Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA bupivacaine-meloxicam (extended release), Bupivacaine, Ketorolac - Periarticular Block, Osteoarthritis (OA) | Phase 4 | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 150 | 2026-09-03 | 2026-10-28 |
| The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers. Psilocybin (drug), Placebo - Healthy Participants, Placebo - Control | Phase 1 | Not yet recruiting | Gabriella Gobbi | 50 | 2026-09-01 | 2026-02-25 |
| CoQ10 Effects on MDM Liver Fat Via FibroTouchI. Coenzyme Q10 (drug), Only undergo baseline assessments without intervention. - Mitochondrial Diabetes | Not applicable | Not yet recruiting | The 95th Hospital of Putian，Putian, Fujian, China | 30 | 2026-09-01 | 2026-08-05 |
| Effect of Daprodustat and Epoetin Alpha on Anemia in Patients Not Undergoing Dialysis Epoetin Alfa (drug), Daprodustat - Chronic Kidney Disease (Stages 3b-5), Anemia Associated With Chronic Kidney Disease | Not applicable | Not yet recruiting | Services Hospital, Lahore | 60 | 2026-09-01 | 2026-08-10 |
| Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies Transcranial Magnetic Stimulation, Psilocybin (drug), Neurofeedback - PTSD, PTSD - Post Traumatic Stress Disorder | Phase 2 | Not yet recruiting | University of New Mexico | 150 | 2026-08-31 | 2026-08-04 |
| Intranasal Delivery of Octreotide for Treatment of Diabetic Macular Edema Octreotide (drug), Placebo - Diabetic Macular Edema | Phase 1 | Withdrawn | University of Alabama at Birmingham | 2026-08-31 | 2026-10-13 | |
| A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors VMD-102 - Hepatocellular Carcinoma (HCC), Metastatic Uveal Melanoma | Phase 1 / Phase 2 | Recruiting | VM Discovery, Inc. | 111 | 2026-07-16 | 2026-08-19 |
| The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease Psilocybin (drug) - Depression, Parkinson's Disease (PD) | Phase 2 | Recruiting | Yale University | 40 | 2026-07-10 | 2026-09-28 |
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Pain (11) · Carcinoma, Hepatocellular (10) · Pain, Postoperative (10) · Hypertension (8) · Schizophrenia (8) · HIV Infections (7) · Neoplasms (7) · Carcinoma, Non-Small-Cell Lung (6) · Parkinson Disease (6) · Renal Insufficiency, Chronic (6) · Depression (5) · Heart Failure (5) · Neoplasm Metastasis (5) · Pulmonary Disease, Chronic Obstructive (5) · Anemia (4)
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest (6) · Medical University of Vienna (6) · Assistance Publique - Hôpitaux de Paris (5) · Sun Yat-sen University (5) · University Health Network, Toronto (5) · University Hospital, Clermont-Ferrand (5) · Yale University (5) · Ain Shams University (4) · Assiut University (4) · Chinese University of Hong Kong (4) · Regional Hospital Holstebro (4) · Technische Universität Dresden (4) · ANRS, Emerging Infectious Diseases (3) · Atatürk Chest Diseases and Chest Surgery Training and Research Hospital (3) · Cairo University (3)
United States (101) · China (40) · France (31) · Germany (31) · Canada (26) · Egypt (18) · Turkey (Türkiye) (16) · Spain (11) · United Kingdom (11) · Italy (9) · Taiwan (9) · Austria (8) · Belgium (8) · Japan (8) · Australia (7)
Erling B Pedersen, Professor (4) · Gabriele Fuchsjaeger-Mayrl, MD (4) · Genevieve Chene, MD, PhD (4) · Manoj K Karmakar, MD (4) · Wilhelm Kirch, MD (4) · Ming Shi, MD (3) · Musa Zengin, MD (3) · Bo Wang, MD PhD (2) · Jean-Michel Molina, MD, PhD (2) · Jesper N Bech, MD, Ph.D. (2) · Jesper N Bech, MD, Ph.d. (2) · Joseph Jankovic, MD (2)
PMID 11732559, PMID 12064356, PMID 15023160, PMID 15060509, PMID 15456093, PMID 15583741, PMID 15717256, PMID 15784740, PMID 15890495, PMID 15978266, PMID 16002461, PMID 16194720, PMID 16495395, PMID 16785215, PMID 16816065, PMID 17101615, PMID 17119142, PMID 17185637, PMID 17434849, PMID 17554116, PMID 17591032, PMID 17638804, PMID 17709660, PMID 17766511, PMID 18052570, PMID 18425621, PMID 18461895, PMID 18536865, PMID 18702902, PMID 19074961, PMID 19128645, PMID 19696440, PMID 19780472, PMID 19933411, PMID 19958860, PMID 20025989, PMID 20122369, PMID 20643821, PMID 20819978, PMID 20843990, PMID 20887414, PMID 21036772, PMID 21060071, PMID 21248083, PMID 21514698, PMID 21607551, PMID 21704313, PMID 21798505, PMID 21918522, PMID 22030902
2004 (3), 2005 (1), 2008 (1), 2014 (1), 2016 (1), 2017 (1), 2025 (1), K01DA046649 (1), K23AA000222 (1), P01HL059412 (1), P30CA043703 (1), R00CA242589 (1), R01DA016834 (1), R01DA054201 (1), R01HL057529 (1)