52 completed, 35 unknown, 13 recruiting, 11 not yet recruiting. 66 Not applicable, 27 Phase 2, 14 Phase 3, 9 Phase 4, 8 Phase 1.
Follow Cicatrix, Hypertrophic: new trials by email Literature Review of Cicatrix, Hypertrophic trials Research Report on Cicatrix, Hypertrophic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II Clinical Study on Preliminary Efficacy and Safety of ETD-001 Gel for Hypertrophic Scars ETD-001 gel, Placebo - Hypertrophic Scars | Phase 2 | Not yet recruiting | Etern Therapeutics Wuxi Limited | 90 | 2027-02-28 | 2026-10-23 |
| Hypertrophic Scar Prosthetic Pressure in Burn Amputee Skin assessment of prothesis interface and control area, Interface pressure - Amputation Stump, Burn Injury | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 12 | 2026-09-01 | 2026-09-30 | |
| Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars Fractional Ablative CO₂ Laser, Triamcinolone Acetonide, Fluorouracil (5-FU) - Burn, Hypertrophic Scars | Not applicable | Not yet recruiting | University of California, Davis | 65 | 2026-08-22 | 2026-08-24 |
| Polidocanol 1% and Steroid in Keloids and Hypertrophic Scars Group 1 (polidocanol 1% group):, Group 2 (Triamcinolone acetonide group):, Group 3 (combined Triamcinolone acetonide and polidocanol 1% group): - Keloid and Hypertrophic Scars | Not applicable | Not yet recruiting | Sohag University | 90 | 2026-08-01 | 2026-05-26 |
| Scar Gel Product Family Clinical Investigation Dermatix, Dermatix Ultra - Hypertrophic Scars, Keloids | Not yet recruiting | Hanson Medical, Inc. | 150 | 2026-07-01 | 2026-07-06 | |
| Topical Cryotherapy and Keloid/Hypertrophic Scars Cryotherapy with liquid nitrogen, Intralesional Triamcinolone 10 mg/ml - Keloid Scars, Hypertrophic Scars | Phase 3 | Recruiting | Sonal Choudhary | 30 | 2026-06-10 | 2026-06-12 |
| Nano-Fat Grafting for Post-Burn Scars on the Chest, Shoulders, and Back Autologous Nano-Fat Grafting - Hypertrophic Scars, Post-burn Scars | Not applicable | Not yet recruiting | Assiut University | 55 | 2026-06-01 | 2026-04-29 |
| Surgical Care And Recovery With Laser Evaluation Trial (SCARLET) ProFractional Laser Therapy and/or Broadband Light (BBL) Treatment - Post-surgical Scars, Hypertrophic Scars | Not applicable | Not yet recruiting | AdventHealth | 150 | 2026-04-01 | 2026-01-22 |
| A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture Technique Intervention 1: 5-0 Slow-absorbable PDS suture, Intervention 2: 5-0 Fast-absorbable Vicryl suture - Ultra Tension-Reducing Suture Technique | Not applicable | Recruiting | Zhenzhen Zhang | 20 | 2026-03-01 | 2026-06-10 |
| Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil Chitosan cream, Silicone Gel, Olive Oil Topical Oil - Hypertrophic Scars | Not applicable | Recruiting | Universiti Sains Malaysia | 120 | 2025-12-21 | 2026-01-02 |
| Remimazolam vs Propofol in Laser Burn Cases Remimazolam besylate, Propofol - Burn Scar, Hypertrophic Scarring | Phase 4 | Recruiting | Medical University of South Carolina | 136 | 2025-11-12 | 2025-11-20 |
| An Innovative Image-Based Method for Extensibility Assessment Traditional physical therapy - Hypertrophic Scar | Not applicable | Completed | Cairo University | 90 | 2025-08-15 | 2026-10-15 |
| Cost-Effectiveness of ESWT Plus Rehabilitation vs Rehabilitation Alone in Post-Burn Scars ESWT Combined with Standard Rehabilitation, Standard Rehabilitation Therapy Alone - Hypertrophic Scar | Not applicable | Recruiting | Al Hayah University In Cairo | 104 | 2025-04-22 | 2025-04-06 |
| Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars Scar gel, Scar gel comparator - Acceptability Study, Real-use Conditions | Phase 1 / Phase 2 | Recruiting | Herbarium Laboratorio Botanico Ltda | 80 | 2025-04-03 | 2025-09-11 |
| Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming Mastectomy Brijjit® BP100-6 and BP-75, Control: Standard of care and normal wound dressing - Gender Dysphoria, Mastectomy | Not applicable | Terminated | University of California, San Francisco | 7 | 2025-02-03 | 2026-08-25 |
| Pulsed High Intensity Laser Versus Extracorporeal Shockwave Therapy on Hypertrophic Scar Post Burn pulsed high intensity laser therapy, Extracorporeal shockwave therapy - Hypertrophic Scar | Not applicable | Not yet recruiting | Cairo University | 60 | 2025-01-26 | 2025-01-31 |
| Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry 3D-Pictures - Keloid Scar Following Surgery, Scars, Hypertrophic | Recruiting | University of Zurich | 20 | 2025-01-10 | 2025-02-07 | |
| Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic Scarring 3D scan measurment - Burns, Hypertrophic Scar | Not applicable | Recruiting | Centre Hospitalier Régional Metz-Thionville | 25 | 2025-01-10 | 2026-06-24 |
| Microporous Tape and Post Surgical Scars Microporous tape, Tradition physical therapy - Microporous Tape, Hypertrophic Scars | Not applicable | Not yet recruiting | Cairo University | 44 | 2025-01-07 | 2025-01-10 |
| Treatment of Hypertrophic Scars Using Fractional CO2 Laser Alone in Comparison With Adding Botulinum Toxin Either Through Intralesional Injection or Assisted Drug Delivery Botulinum toxin type A (Botox®, Allergan) - Hypertrophic Scars | Not applicable | Completed | Cairo University | 48 | 2025-01-01 | 2026-01-22 |
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Keloid (40) · Cicatrix (37) · Burns (17) · Hypertrophy (3) · Surgical Wound (3) · Fibrosis (2) · Hyperpigmentation (2) · Pain, Postoperative (2) · Pruritus (2) · Surgical Wound Infection (2) · Wounds and Injuries (2) · Acne Vulgaris (1) · Alopecia Areata (1) · Blister (1)
Pathologic Processes (128) · Pathological Conditions, Signs and Symptoms (128) · Fibrosis (126) · Cicatrix (91) · Skin and Connective Tissue Diseases (47) · Collagen Diseases (40) · Connective Tissue Diseases (40) · Wounds and Injuries (20) · Skin Diseases (9) · Pathological Conditions, Anatomical (4) · Signs and Symptoms (4) · Infections (3) · Neurologic Manifestations (3) · Postoperative Complications (3) · Neoplasms (2)
Botulinum Toxins (3) · Botulinum Toxins, Type A (3) · Extracorporeal Shockwave Therapy (3) · Percutaneous Collagen Induction (3) · Saline Solution (3) · Silicone Gels (3) · Sodium Chloride (3) · Triamcinolone Acetonide (3) · abobotulinumtoxinA (3) · Adrenal Cortex Hormones (2) · Athletic Tape (2) · Cryotherapy (2) · Fluorouracil (2) · Lasers, Dye (2) · Lidocaine (2)
Cairo University (10) · Hangang Sacred Heart Hospital (3) · Mahidol University (3) · Massachusetts General Hospital (3) · The Hong Kong Polytechnic University (3) · Alexandria University (2) · Amsterdam UMC, location VUmc (2) · Assiut University (2) · Henry Ford Health System (2) · Hugel (2) · Kaohsiung Veterans General Hospital. (2) · Medstar Health Research Institute (2) · Nova Scotia Health Authority (2) · Olix Pharmaceuticals, Inc. (2) · Pfizer (2)
United States (37) · Egypt (14) · Canada (8) · China (7) · Taiwan (6) · South Korea (5) · Thailand (5) · Netherlands (3) · Pakistan (3) · Brazil (2) · France (2) · Germany (2) · Honduras (2) · Hong Kong (2) · Italy (2)
David Ozog, MD (2) · Jonathan Friedstat, MD (2) · Michael H Tirgan, MD (2) · Michiel CE van Leeuwen, MD (2) · Pamela Pavco, PhD (2) · A M Abd Elbaky, Professor (1) · Adam Weinfeld, MD (1) · Ahmed Ali, Assistant Proffesor (1) · Alexander Meves, MD (1) · Alexander Neumeister, MD (1) · Alexandra Trimaille (1) · Alexes Hazen, MD (1)
PMID 1003586, PMID 10077078, PMID 10808705, PMID 10927682, PMID 11242330, PMID 11348456, PMID 11887386, PMID 12028527, PMID 12028528, PMID 12032371, PMID 12534517, PMID 12711943, PMID 12845617, PMID 15113289, PMID 15209788, PMID 15253184, PMID 16079683, PMID 16163087, PMID 16254707, PMID 16267427, PMID 16413399, PMID 16437463, PMID 16575391, PMID 16696385, PMID 17214728, PMID 18182896, PMID 18534768, PMID 18555763, PMID 18843115, PMID 19215252, PMID 19341651, PMID 19621835, PMID 19802513, PMID 20009818, PMID 2009067, PMID 20440184, PMID 21332916, PMID 21551963, PMID 22090252, PMID 22177632, PMID 22907286, PMID 23027220, PMID 23102873, PMID 23716460, PMID 24085055, PMID 24108222, PMID 24501476, PMID 24898579, PMID 25257046, PMID 2529659
2009 (1)