8 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 8, Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1 |
Follow Procedural Sedation: new trials by email Literature Review of Procedural Sedation trials Research Report on Procedural Sedation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department. Ketamine (1 mg/kg), propofol, Dexmedetomidine - Procedural Sedation | Phase 4 | Not yet recruiting | Sultan Qaboos University | 100 | 2026-10-10 | 2026-10-15 |
| Remimazolam vs Propofol in Laser Burn Cases Remimazolam besylate, Propofol - Burn Scar, Hypertrophic Scarring | Phase 4 | Recruiting | Medical University of South Carolina | 136 | 2025-11-12 | 2025-11-20 |
| The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study Precedex (Dexmedetomidine) 200 MCG in 2 ML Injection, C group: Patients received saline infusion over 10 minutes - GIT Endoscopy, Procedural Sedation | Phase 4 | Unknown | Theodor Bilharz Research Institute | 52 | 2024-05-01 | 2024-05-16 |
| Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy Ciprofol, Propofol, Sufentanil - Bronchoscopy, Procedural Sedation | Phase 4 | Completed | Wenzhou Central Hospital | 100 | 2022-08-01 | 2026-08-04 |
| Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implantation Propofol, Dexmedetomidine - Transcatheter Aortic Valve Replacement, Procedural Sedation | Phase 4 | Completed | University Medical Centre Ljubljana | 70 | 2019-01-15 | 2023-05-10 |
| Pharmacological Characteristics of Intranasally Given Dexmedetomidine in Paediatric Patients Dexmedetomidine - Procedural Sedation | Phase 4 | Completed | Turku University Hospital | 50 | 2017-01-01 | 2018-09-12 |
| Can we Get Conscious Sedation by Combining Dexmedetomidine With Alfentanil? Dexmedetomidine, Alfentanil - Procedural Sedation | Phase 4 | Completed | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 40 | 2015-02-01 | 2016-07-06 |
| Dexmedetomidine for Sedation During Radiological Interventional Procedures Dexmeditomedine - Procedural Sedation | Phase 4 | Completed | National Cancer Institute, Egypt | 40 | 2014-01-01 | 2016-04-19 |
| Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy Midazolam, Propofol - Procedural Sedation | Phase 4 | Completed | Infante, Javier Molina, M.D. | 135 | 2011-06-01 | 2016-05-25 |
| Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery Fospropofol disodium, Placebo + Midazolam, Fentanyl - Procedural Sedation, Regional Anesthesia Block | Phase 4 | Terminated | Mayo Clinic | 13 | 2011-02-01 | 2012-06-29 |
| Safety and Efficacy of Propofol Only Sedation in Oral and Maxillofacial Surgery Propofol - Procedural Sedation, Propofol | Phase 4 | Unknown | Atlantic Center for Oral and Maxillofacial Surgery | 169 | 2011-01-01 | 2010-10-25 |
| Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation Propofol, 1:1 Propofol/Ketamine, 4:1 Propofol/Ketamine - Procedural Sedation | Phase 4 | Completed | Hennepin Healthcare Research Institute | 271 | 2010-11-01 | 2015-07-14 |
| Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department Ketamine/Midazolam, Propofol - Procedural Sedation | Phase 4 | Completed | Tel-Aviv Sourasky Medical Center | 60 | 2008-11-01 | 2010-08-03 |
Emergencies (4) · Agnosia (1) · Cicatrix, Hypertrophic (1) · Respiratory Insufficiency (1)
Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Disease Attributes (4) · Cicatrix (1) · Fibrosis (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1) · Perceptual Disorders (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Signs and Symptoms (1)
Propofol (8) · Dexmedetomidine (4) · Ketamine (3) · Midazolam (3) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Alfentanil (1) · Fentanyl (1) · Injections (1) · Saline Solution (1) · Sufentanil (1) · fospropofol (1)
Atlantic Center for Oral and Maxillofacial Surgery (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Hennepin Healthcare Research Institute (1) · Infante, Javier Molina, M.D. (1) · Mayo Clinic (1) · Medical University of South Carolina (1) · National Cancer Institute, Egypt (1) · Sultan Qaboos University (1) · Tel-Aviv Sourasky Medical Center (1) · Theodor Bilharz Research Institute (1) · Turku University Hospital (1) · University Medical Centre Ljubljana (1) · Wenzhou Central Hospital (1)
United States (3) · Egypt (2) · Canada (1) · China (1) · Finland (1) · Israel (1) · Oman (1) · Slovenia (1) · Spain (1)
Ashraf Fathy Elshehry, FRCEM-UK (1) · Ayat A Hassan, MD (1) · Ben Davis, DDS FRCD(C) (1) · Franck Verschuren, MD, PhD (1) · Ghada M Bashandy, MD (1) · James R Miner, MD (1) · Javier Molina-Infante, MD (1) · John B Leslie, MD MBA (1) · Maie K Helaly, MD (1) · Panu Uusalo, MD (1) · Pinchas Halpern, MD (1) · Rishi Patel, MD (1) · Wafaa T Salem, MD (1)
PMID 12826556, PMID 15505441, PMID 18072987, PMID 19845550, PMID 22615015, PMID 25441247