18 completed, 4 terminated, 2 not yet recruiting, 2 recruiting. 8 Phase 2, 8 Phase 3, 7 Phase 4, 5 Not applicable, 3 Phase 1.
Follow fospropofol: new trials by email Literature Review of fospropofol trials Research Report on fospropofol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Fospropofol Disodium TIVA and IVIH on Surgical Field Quality in Adult ESS Fospropofol disodium, Propofol - Fospropofol Disodium | Not applicable | Recruiting | Tongji Hospital | 144 | 2026-07-12 | 2026-09-17 |
| Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy Fospropofol disodium plus sufentanil for anesthesia induction, Propofol plus sufentanil for anesthesia induction - Anesthesia for Urologic Endoscopic Surgery, Urinary Calculi | Phase 4 | Not yet recruiting | Shiyou Wei | 190 | 2026-06-26 | 2026-06-24 |
| Fospropofol Disodium ED95 for Elderly Spinal Anesthesia Sedation Fospropofol Disodium - Lower Extremity Surgery | Phase 4 | Not yet recruiting | Ya-Qun Zhou | 60 | 2026-01-01 | 2026-01-13 |
| Clinical Study of Fospropofol Disodium for Injection in the Painless Endoscopic Diagnosis and Treatment fospropofol Disodium for injection, Propofol - Efficacy and Safety | Not applicable | Completed | Affiliated Hospital of Nantong University | 426 | 2025-08-12 | 2026-08-17 |
| Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial Fospropofol, Propofol - Drug Safety | Phase 4 | Recruiting | Hui Xu | 373 | 2024-09-15 | 2025-04-16 |
| ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia fospropofol - Elective Surgery | Phase 4 | Completed | Tongji Hospital | 330 | 2024-05-01 | 2025-08-14 |
| Safety and Efficacy of Fospropofol vs Propofol During Invasive Mechanical Ventilation. Fospropofol - Invasive Mechanical Ventilation | Not applicable | Completed | Henan Provincial People's Hospital | 200 | 2024-04-12 | 2026-05-29 |
| Efficacy and Safety of Fospropofol Disodium Versus Propofol for Deep Sedation in Critically Ill Patients Fospropofol disodium for injection, Propofol - Critical Illness | Phase 2 | Unknown | Xiaobo Yang, MD | 60 | 2023-06-01 | 2023-07-05 |
| Efficacy and Safety of Fospropofol Disodium Versus Propofol for Sedation in Mechanically Ventilated ICU Patients Fospropofol disodium for injection, Propofol - Critical Illness | Phase 2 | Completed | Xiaobo Yang, MD | 60 | 2022-08-10 | 2023-09-21 |
| Evaluate The Effectiveness Of Fospropofol (Lusedra®) For Induction Of Anesthesia Fospropofol (Lusedra®) 6.5, Fospropofol (Lusedra®) 10, Fospropofol (Lusedra®) 12 - Interstitial Cystitis | Not applicable | Withdrawn | Grace Shih, MD | 2011-06-01 | 2012-10-03 | |
| Fospropofol for Sedation During Elective Awake Intubation fospropofol - Impaired Airway Clearance | Not applicable | Withdrawn | The Cleveland Clinic | 2011-02-01 | 2017-04-18 | |
| Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery Fospropofol disodium, Placebo + Midazolam, Fentanyl - Procedural Sedation, Regional Anesthesia Block | Phase 4 | Terminated | Mayo Clinic | 13 | 2011-02-01 | 2012-06-29 |
| A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion arm 1, LUSEDRA, Propofol (arm 3) - Monitored Anesthesia Care | Phase 1 | Completed | Eisai Inc. | 20 | 2011-01-01 | 2015-11-03 |
| A PK/PD Study of Fospropofol Disodium Compared With Propofol Injectable Emulsion Fospropofol disodium, propofol - Anesthesia | Phase 4 | Completed | Eisai Inc. | 36 | 2010-11-01 | 2017-01-27 |
| A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure Lusedra, Propofol - Lactating Women | Phase 1 | Completed | Eisai Inc. | 10 | 2010-11-01 | 2015-11-03 |
| Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol Fospropofol, Propofol/Lidocaine - Complication of Injection, Pain | Phase 4 | Completed | NYU Langone Health | 116 | 2010-08-01 | 2017-12-29 |
| A Study to Assess the Efficacy and Safety of Fospropofol Disodium Fospropofol disodium - Drug Safety | Phase 1 | Completed | West China Hospital | 80 | 2010-03-01 | 2011-01-06 |
| A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures. AQUAVAN® (fospropofol disodium) Injection - Procedural Sedation | Phase 2 / Phase 3 | Completed | Eisai Inc. | 123 | 2006-05-01 | 2012-06-20 |
| An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy AQUAVAN® (fospropofol disodium) Injection - Bronchoscopy, Anesthesia | Phase 3 | Completed | Eisai Inc. | 250 | 2006-04-01 | 2008-11-07 |
| An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI - Conscious Sedation | Phase 3 | Completed | Eisai Inc. | 300 | 2006-03-01 | 2008-11-07 |
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Eisai Inc. (15) · Tongji Hospital (2) · Xiaobo Yang, MD (2) · Affiliated Hospital of Nantong University (1) · Grace Shih, MD (1) · Henan Provincial People's Hospital (1) · Hui Xu (1) · Mayo Clinic (1) · NYU Langone Health (1) · Shiyou Wei (1) · The Cleveland Clinic (1) · West China Hospital (1) · Ya-Qun Zhou (1)
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