244 completed, 77 unknown, 43 terminated, 40 recruiting. 463 Phase 2, 112 Phase 3, 80 Phase 1.
Follow Pregnancy Complications: new trials by email Literature Review of Pregnancy Complications trials Research Report on Pregnancy Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus Semaglutide (Wegovy) weekly injection - Gestational Diabetes Mellitus (GDM), Metabolic Syndrome | Phase 2 / Phase 3 | Not yet recruiting | University of Massachusetts, Worcester | 226 | 2027-09-01 | 2026-09-28 |
| Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders Ravulizumab - Preeclampsia | Phase 2 | Recruiting | Mayo Clinic | 14 | 2027-04-01 | 2026-10-22 |
| Little Lungs Study Calfactant, Budesonide - Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome | Phase 1 / Phase 2 | Not yet recruiting | University of Wisconsin, Madison | 24 | 2027-02-01 | 2026-11-02 |
| CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO) Caffeine citrate, Saline (NaCl 0,9 %) (placebo) - Meconium Aspiration Syndrome | Phase 2 | Not yet recruiting | University of Alberta | 20 | 2026-11-12 | 2026-10-26 |
| Furosemide vs Placebo in Severe Preeclampsia Postpartum Furosemide, Folic Acid 5 MG - Severe Preeclampsia | Phase 2 | Not yet recruiting | Universidad Nacional Autonoma de Honduras | 186 | 2026-11-02 | 2026-11-05 |
| High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants High-energy group, Standard-energy group - Extreme Prematurity, Enteral Nutrition | Phase 1 / Phase 2 | Recruiting | University of Alabama at Birmingham | 150 | 2026-09-21 | 2026-09-24 |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
| Dipyridamole for Early-Onset Preeclampsia: A Pilot Study of Feasibility, Pharmacokinetics, and Biological Effects Dipyridamole 75 MG - Preeclampsia (PE), Hypertension ,Pregnancy | Phase 1 / Phase 2 | Not yet recruiting | Hadassah Medical Organization | 15 | 2026-09-01 | 2026-07-31 |
| Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants Nicotinamide Riboside (NR), Placebo - Preterm Birth, Inadequate Milk Production | Phase 2 / Phase 3 | Recruiting | University of California, Davis | 40 | 2026-08-19 | 2026-09-14 |
| Hyperemesis Gravidarum Risk Reduction With Metformin Metformin Extended Release Oral Tablet - Hyperemesis Gravidarum | Phase 1 / Phase 2 | Recruiting | University of Southern California | 224 | 2026-07-13 | 2026-07-22 |
| Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent Miscarriage Placebo control, Recombinant G-CSF - Recurrent Pregnancy Loss, Recurrent Miscarriages | Phase 2 | Recruiting | Fakih IVF Fertility Center | 150 | 2026-07-10 | 2026-07-24 |
| Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation Dexmedetomidine (IV) 0.5 mcg/kg, Placebo - Abortion, Stillbirth | Phase 2 / Phase 3 | Withdrawn | Stanford University | 2026-07-01 | 2026-07-17 | |
| Tocilizumab for the Treatment of Refractory Granulomatous Lobular Mastitis Tocilizumab - Granulomatous Lobular Mastitis, Granulomatous Mastitis | Phase 1 / Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 31 | 2026-06-01 | 2026-05-19 |
| Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy Methotrexate (drug), Letrozole 2.5Mg Tab - Ectopic Pregnancy | Phase 2 | Not yet recruiting | Kafrelsheikh University | 70 | 2026-06-01 | 2026-06-03 |
| Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage Oxytocin sublingual, Oxytocin IM - Post Partum Hemorrhage | Phase 2 | Not yet recruiting | Insud Pharma | 330 | 2026-05-30 | 2026-04-23 |
| Improving Preterm Kidney Outcomes With Caffeine Caffeine citrate, Placebo - Kidney Injury, Pre-Term | Phase 2 | Recruiting | University of Wisconsin, Madison | 114 | 2026-05-28 | 2026-09-18 |
| Neonatal Outcomes on Direct Fetal Intravenous Immunoglobulin During Intrauterine Transfusion for Rhesus Isoimmunization Intrauterine Transfusion, Intravenous immunoglobulin (IVIG) - Hemolytic Disease of the Newborn, Fetal Anemia | Phase 2 | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 30 | 2026-05-25 | 2026-10-21 |
| Pressure Targeting During High Flow Therapy in Premature Infants Pressure Targeted High Flow, CPAP - Preterm Infants, Respiratory Distress Syndrome (Neonatal) | Phase 2 | Not yet recruiting | University of Texas at Austin | 78 | 2026-05-01 | 2026-02-18 |
| Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section Calcium Chloride, Placebo - Post Partum Haemorrhage, Cesarean Section Surgery | Phase 2 | Not yet recruiting | Pak Emirates Military Hospital | 182 | 2026-05-01 | 2026-04-24 |
| MINImising Total Radiation EXposure in Preterm Infants Lung ultrasound group, Standard Care - Neonatal Respiratory Distress Syndrome, PreTerm Neonate | Phase 2 | Recruiting | Western Health, Australia | 180 | 2026-04-13 | 2026-04-16 |
Showing 20 of 463. Sign in to see all of them.
Premature Birth (162) · Pre-Eclampsia (56) · Postpartum Hemorrhage (34) · Depression, Postpartum (33) · Bronchopulmonary Dysplasia (32) · Diabetes, Gestational (26) · Gestational Trophoblastic Disease (25) · Abortion, Spontaneous (21) · Obstetric Labor, Premature (21) · Respiratory Distress Syndrome (12) · Depression (11) · Hypertension (11) · Hypertension, Pregnancy-Induced (11) · Fetal Growth Retardation (10)
Female Urogenital Diseases and Pregnancy Complications (463) · Urogenital Diseases (463) · Obstetric Labor Complications (226) · Obstetric Labor, Premature (154) · Pathological Conditions, Signs and Symptoms (122) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (93) · Pathologic Processes (89) · Puerperal Disorders (69) · Infant, Newborn, Diseases (53) · Respiratory Tract Diseases (52) · Hypertension, Pregnancy-Induced (47) · Infant, Premature, Diseases (45) · Lung Diseases (45) · Cardiovascular Diseases (41)
Misoprostol (23) · Saline Solution (16) · Sodium Chloride (14) · Oxytocin (13) · Aspirin (12) · Progesterone (12) · Metformin (9) · Nifedipine (9) · Tranexamic Acid (9) · Sildenafil Citrate (8) · Letrozole (7) · Methotrexate (7) · Glucose (6) · Indomethacin (6) · Acetaminophen (5)
Assiut University (17) · Ain Shams University (14) · NICHD Neonatal Research Network (11) · Stanford University (10) · The University of Texas Health Science Center, Houston (7) · Benha University (6) · Centers for Disease Control and Prevention (5) · Massachusetts General Hospital (5) · University of Alabama at Birmingham (5) · Ain Shams Maternity Hospital (4) · Assistance Publique - Hôpitaux de Paris (4) · Cairo University (4) · Fred Hutchinson Cancer Center (4) · Seoul National University Hospital (4) · Sunnybrook Health Sciences Centre (4)
United States (189) · Egypt (47) · Canada (34) · China (19) · France (13) · Israel (12) · Pakistan (10) · Spain (10) · South Korea (9) · United Kingdom (9) · Australia (7) · Brazil (7) · Iran (7) · Denmark (5) · Germany (5)
Barbara J. Stoll, MD (6) · Edward F. Donovan, MD (6) · Seetha Shankaran, MD (6) · Richard A. Ehrenkranz, MD (5) · Sheldon B. Korones, MD (5) · Waldemar A. Carlo, MD (5) · Andrew Combs, MD (4) · Avroy A. Fanaroff, MD (4) · Charles R. Bauer, MD (4) · James A. Lemons, MD (4) · Jon E. Tyson, MD MPH (4) · Abhik Das, PhD (3) · Dale L. Phelps, MD (3) · David K. Stevenson, MD (3) · Jeffrey R Wozniak, Ph.D. (3)
PMID 35947046, PMID 36996264, PMID 20008425, PMID 25496504, PMID 29282009, PMID 39956364, PMID 10379020, PMID 10467792, PMID 10654946, PMID 10908457, PMID 11502292, PMID 11581447, PMID 12892684, PMID 14600674, PMID 15342835, PMID 15507947, PMID 15520109, PMID 15713717, PMID 15713907, PMID 15774846, PMID 15954876, PMID 16390366, PMID 16581405, PMID 16842791, PMID 16900525, PMID 17197859, PMID 17634155, PMID 17650319, PMID 18536599, PMID 18676556, PMID 18695118, PMID 19117865, PMID 19432563, PMID 19843000, PMID 19919718, PMID 19935025, PMID 19943825, PMID 20009308, PMID 20187965, PMID 20375733, PMID 20455694, PMID 20455772, PMID 20525274, PMID 20573151, PMID 20884642, PMID 20920070, PMID 20963840, PMID 20980771, PMID 21083860, PMID 21091415
U10HD021385 (9), U10HD021364 (8), U10HD027853 (8), U10HD027880 (7), U10HD027851 (6), U10HD027856 (6), U10HD027871 (6), U10HD027904 (6), U10HD034216 (6), M01RR008084 (5), U10HD021373 (5), U10HD021415 (5), U10HD036790 (5), U10HD040689 (5), U10HD021397 (4)