1969 completed, 704 unknown, 341 recruiting, 197 terminated. 1717 Not applicable, 275 Phase 3, 232 Phase 2, 217 Phase 4, 108 Phase 1.
Follow Obstetric Labor Complications: new trials by email Literature Review of Obstetric Labor Complications trials Research Report on Obstetric Labor Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Sodium Bicarbonate for the Prevention of Labour Dystocia oral sodium bicarbonate - Labour Dystocia | Not applicable | Not yet recruiting | Liz Darling | 200 | 2027-10-01 | 2026-10-23 |
| A Study to Lower Blood Pressure One Year After Childbirth in Women Who Had Preeclampsia The intervention in the GESTA-SCORE study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs). - Adverse Pregnancy Outcomes, Cardiovascular Diseases | Not applicable | Not yet recruiting | Maternal-Infantil Vall d´Hebron Hospital | 150 | 2027-06-01 | 2026-11-03 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism | Not yet recruiting | University Hospital, Lille | 1600 | 2027-03-01 | 2026-05-22 | |
| Little Lungs Study Calfactant, Budesonide - Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome | Phase 1 / Phase 2 | Not yet recruiting | University of Wisconsin, Madison | 24 | 2027-02-01 | 2026-11-02 |
| Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial Chinstrap - Apnea of Prematurity, Intermittent Hypoxemia | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 20 | 2027-01-15 | 2026-10-27 |
| Eye Tracking and Autism in Former Preterm Infants Eye-tracking device - Autism, Prematurity | Not applicable | Not yet recruiting | Indiana University | 40 | 2027-01-04 | 2026-08-14 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care Lateral, Prone, Incubator care - Kangaroo Care, Premature Infant | Not applicable | Not yet recruiting | Hospital Universitario 12 de Octubre | 314 | 2027-01-01 | 2026-03-16 |
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| Fetoscopic Laser Photocoagulation in Management of Vasa Previa Fetoscopic Laser Photocoagulation - Vasa Previa, Pregnancy Complications | Not applicable | Withdrawn | Boston Children's Hospital | 2026-12-01 | 2026-06-02 | |
| Prospective Twin Pregnancy Cohort at Montpellier University Hospital Biological samples from the mother, Biological samples from the twins - Pregnancy, Twin | Not yet recruiting | University Hospital, Montpellier | 360 | 2026-12-01 | 2026-06-18 | |
| Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system - Retinopathy of Prematurity (ROP) | Not applicable | Recruiting | Duke University | 175 | 2026-12-01 | 2026-09-17 |
| Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial Family-centered developmental training intervention - Preterm | Not applicable | Not yet recruiting | Seoul National University Hospital | 170 | 2026-12-01 | 2026-10-20 |
| Early Nutrition and Heart Structure and Function in Preterm Infants During the First Year of Life echocardiography - Cardiac Abnormalities, Nutrient Intake | Not yet recruiting | Assiut University | 80 | 2026-12-01 | 2026-11-05 | |
| nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 Weeks nCPAP-NAVA-backup mode, nCPAP mode - Apnea of Prematurity | Not applicable | Not yet recruiting | University Hospital, Geneva | 25 | 2026-12-01 | 2026-11-06 |
| Comparison of Effect of Two Different Doses of Intravenous Oxytocin on Patients Undergoing Elective Cesarean Section Oxytocin 5 IU (Low Dose), Oxytocin 10 IU (High Dose) - Postpartum Hemorrhage, Uterine Atony | Not applicable | Not yet recruiting | Shalamar Hospital | 120 | 2026-12-01 | 2026-11-06 |
| NICU-to-Home Dyadic Support for Very Preterm Infants and Families Homebased SPEEDI, Telehealth SPEEDI - Preterm Birth, Very Preterm Infant | Not applicable | Not yet recruiting | University of Minnesota | 40 | 2026-11-16 | 2026-10-09 |
| Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up - Development Delay, Motor Skills Disorders | Not applicable | Not yet recruiting | Bengisu Boz Gürboğa | 36 | 2026-11-16 | 2026-10-21 |
| The Hemodynamic Impact of High-frequency Oscillatory Ventilation and Periodic Sighs in Preterm Infants Superimposed sigh breaths, High frequency ventilation - Preterm, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Alexandria University | 100 | 2026-11-15 | 2026-10-27 |
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Premature Birth (2533) · Postpartum Hemorrhage (465) · Obstetric Labor, Premature (228) · Bronchopulmonary Dysplasia (155) · Placenta Accreta (144) · Fetal Membranes, Premature Rupture (97) · Respiratory Distress Syndrome (96) · Pre-Eclampsia (89) · Enterocolitis, Necrotizing (78) · Placenta Previa (74) · Pregnancy Complications (73) · Breast Feeding (68) · Pain (66) · Dystocia (49)
Female Urogenital Diseases and Pregnancy Complications (3616) · Urogenital Diseases (3616) · Pregnancy Complications (3543) · Obstetric Labor, Premature (2433) · Pathological Conditions, Signs and Symptoms (1104) · Pathologic Processes (788) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (507) · Puerperal Disorders (491) · Uterine Hemorrhage (462) · Hemorrhage (455) · Respiratory Tract Diseases (390) · Signs and Symptoms (374) · Infant, Newborn, Diseases (341) · Lung Diseases (302)
Oxytocin (127) · Misoprostol (76) · Tranexamic Acid (62) · carbetocin (55) · Saline Solution (50) · Progesterone (48) · Sodium Chloride (43) · Standard of Care (37) · Nifedipine (28) · Umbilical Cord Clamping (26) · Control Groups (24) · Cerclage, Cervical (19) · Indomethacin (19) · Music Therapy (19) · Blood Specimen Collection (18)
Assiut University (77) · Cairo University (58) · Ain Shams University (44) · NICHD Neonatal Research Network (41) · Assistance Publique - Hôpitaux de Paris (36) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (34) · University of Alabama at Birmingham (32) · Stanford University (25) · Aswan University Hospital (24) · Gynuity Health Projects (23) · Christiana Care Health Services (21) · University of Utah (21) · University of Pennsylvania (19) · Columbia University (18) · University of Calgary (18)
United States (910) · Turkey (Türkiye) (341) · Egypt (275) · France (274) · Canada (193) · Italy (139) · Israel (125) · United Kingdom (110) · China (104) · Spain (87) · Germany (76) · Pakistan (51) · Switzerland (51) · Belgium (46) · Brazil (44)
Seetha Shankaran, MD (32) · Barbara J. Stoll, MD (27) · Richard A. Ehrenkranz, MD (25) · Mrinalini Balki, MD (24) · Waldemar A. Carlo, MD (21) · Abhik Das, PhD (19) · Edward F. Donovan, MD (18) · Abbot R. Laptook, MD (17) · David K. Stevenson, MD (15) · James A. Lemons, MD (14) · Jon E. Tyson, MD MPH (14) · Sheldon B. Korones, MD (14) · William Oh, MD (14)
PMID 35947046, PMID 33232518, PMID 32609374, PMID 36996264, PMID 33305842, PMID 33006765, PMID 33169839, PMID 35921693, PMID 36453699, PMID 18275573, PMID 22086108, PMID 28235686, PMID 28456509, PMID 29872859, PMID 30741812, PMID 39147903, PMID 39162220, PMID 8598837, PMID 10429008, PMID 10835060, PMID 11430325, PMID 12114906, PMID 14510324, PMID 14520225, PMID 14523165, PMID 15060228, PMID 15286223, PMID 15507925, PMID 15520109, PMID 15547163, PMID 15713907, PMID 15741371, PMID 15741374, PMID 15930228, PMID 15956871, PMID 15973322, PMID 15995042, PMID 16000352, PMID 16027695, PMID 16107873, PMID 16143580, PMID 16322158, PMID 16396864, PMID 16467730, PMID 16507341, PMID 16549503, PMID 16585322, PMID 16598294, PMID 16615955, PMID 16647401
U10HD021385 (34), U10HD027880 (32), U10HD027851 (31), U10HD027853 (30), U10HD027904 (30), U10HD021364 (29), U10HD021373 (29), U10HD027856 (28), U10HD027871 (26), U10HD034216 (25), M01RR008084 (23), U10HD021397 (21), M01RR000070 (20), U10HD040689 (20), M01RR000750 (19)