Obstetric Labor Complications: Clinical Trials

1956 completed, 710 unknown, 331 recruiting, 197 terminated. 1706 Not applicable, 275 Phase 3, 232 Phase 2, 216 Phase 4, 108 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	1706	Completed 951, Unknown 313, Recruiting 160, Not yet recruiting 94, Terminated 91, Withdrawn 44, Active not recruiting 41, Enrolling by invitation 9, Suspended 3
Phase 3	275	Completed 154, Unknown 40, Terminated 22, Recruiting 20, Withdrawn 18, Not yet recruiting 13, Active not recruiting 6, Enrolling by invitation 1, Suspended 1
Phase 2	232	Completed 123, Unknown 42, Recruiting 21, Terminated 21, Withdrawn 10, Not yet recruiting 9, Active not recruiting 5, Suspended 1
Phase 4	216	Completed 123, Unknown 41, Terminated 19, Recruiting 18, Withdrawn 8, Not yet recruiting 6, Active not recruiting 1
Phase 1	108	Completed 57, Unknown 17, Terminated 11, Recruiting 7, Withdrawn 7, Not yet recruiting 6, Active not recruiting 3
Early Phase 1	29	Completed 16, Unknown 4, Recruiting 3, Withdrawn 3, Active not recruiting 2, Terminated 1

Follow this condition Literature Review of Obstetric Labor Complications trials Research Report on Obstetric Labor Complications

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth		Not yet recruiting	University of Campania Luigi Vanvitelli	600	2027-04-01	2026-10-21
Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism		Not yet recruiting	University Hospital, Lille	1600	2027-03-01	2026-05-22
Eye Tracking and Autism in Former Preterm Infants Eye-tracking device - Autism, Prematurity	Not applicable	Not yet recruiting	Indiana University	40	2027-01-04	2026-08-14
The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm	Not applicable	Not yet recruiting	Leiden University Medical Center	1860	2027-01-01	2026-08-10
Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care Lateral, Prone, Incubator care - Kangaroo Care, Premature Infant	Not applicable	Not yet recruiting	Hospital Universitario 12 de Octubre	314	2027-01-01	2026-03-16
Fetoscopic Laser Photocoagulation in Management of Vasa Previa Fetoscopic Laser Photocoagulation - Vasa Previa, Pregnancy Complications	Not applicable	Withdrawn	Boston Children's Hospital		2026-12-01	2026-06-02
Prospective Twin Pregnancy Cohort at Montpellier University Hospital Biological samples from the mother, Biological samples from the twins - Pregnancy, Twin		Not yet recruiting	University Hospital, Montpellier	360	2026-12-01	2026-06-18
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system - Retinopathy of Prematurity (ROP)	Not applicable	Recruiting	Duke University	175	2026-12-01	2026-09-17
Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial Family-centered developmental training intervention - Preterm	Not applicable	Not yet recruiting	Seoul National University Hospital	170	2026-12-01	2026-10-20
NICU-to-Home Dyadic Support for Very Preterm Infants and Families Homebased SPEEDI, Telehealth SPEEDI - Preterm Birth, Very Preterm Infant	Not applicable	Not yet recruiting	University of Minnesota	40	2026-11-16	2026-10-09
Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up - Development Delay, Motor Skills Disorders	Not applicable	Not yet recruiting	Bengisu Boz Gürboğa	36	2026-11-16	2026-10-21
Initial Oxygen Concentration at Birth in Late-Preterm Infants 60% Oxygen Group - Infants will start in 60% oxygen, 30% Oxygen Group - Infants will start in 30% oxygen - Preterm Birth	Not applicable	Not yet recruiting	University of Alberta	1520	2026-11-01	2026-09-10
PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled Tiotropium tiotropium bromide (Spiriva Respimat) - Bronchial Obstruction, Premature Birth	Phase 4	Not yet recruiting	General University Hospital, Prague	50	2026-11-01	2026-09-18
Elevated Midline Positioning During Diaper Change in Preterm Infants 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change - Infant, Premature, Diseases, Premature Birth of Newborn	Not applicable	Not yet recruiting	Akdeniz University	80	2026-11-01	2026-10-13
Parent-Facilitated Early Oral-Sensory Experience in the NICU for Feeding Outcomes Parent-Facilitated Early Oral-Sensory Experience (PEOE) - Premature Birth, Infant, Premature	Not applicable	Not yet recruiting	Boston College	60	2026-11-01	2026-10-20
Postoperative Pain in Infants Postoperative Pain		Not yet recruiting	Uppsala University Hospital	100	2026-10-30	2026-10-02
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics Trained, standardized patient, MamaAnne Patient Simulator - PPH - Postpartum Hemorrhage, Eclampsia	Not applicable	Not yet recruiting	Medical University of Vienna	72	2026-10-15	2026-10-05
Amnioinfusion for Chorioamnionitis: Targeting Neonatal Brain Injury Biomarkers Intrauterine Pressure Catheter, Standard obstetric care at discretion of delivery provider - Chorioamnionitis Affecting Fetus or Newborn, Amnioinfusion	Not applicable	Not yet recruiting	Medical College of Wisconsin	80	2026-10-15	2026-10-08
Cervical Stiffness in Women With Threatened Preterm Labor Pregnolia System - Preterm Labor, Preterm Birth		Recruiting	Pregnolia AG	100	2026-10-15	2026-10-21
Effect of Automated Oxygen Control on Early-childhood Lung Mechanics Forced oscillometry technique - Prematurity, Respiratory Distress Neonatal		Not yet recruiting	King's College Hospital NHS Trust	60	2026-10-12	2026-10-14

Showing 20 of 3601. Sign in to see all of them.

Narrower conditions

Premature Birth (2520)  ·  Postpartum Hemorrhage (463)  ·  Obstetric Labor, Premature (228)  ·  Bronchopulmonary Dysplasia (152)  ·  Placenta Accreta (144)  ·  Fetal Membranes, Premature Rupture (97)  ·  Respiratory Distress Syndrome (95)  ·  Pre-Eclampsia (89)  ·  Enterocolitis, Necrotizing (78)  ·  Placenta Previa (74)  ·  Pregnancy Complications (73)  ·  Breast Feeding (67)  ·  Pain (66)  ·  Dystocia (49)

Broader conditions

Female Urogenital Diseases and Pregnancy Complications (3601)  ·  Urogenital Diseases (3601)  ·  Pregnancy Complications (3528)  ·  Obstetric Labor, Premature (2420)  ·  Pathological Conditions, Signs and Symptoms (1100)  ·  Pathologic Processes (785)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (504)  ·  Puerperal Disorders (489)  ·  Uterine Hemorrhage (460)  ·  Hemorrhage (453)  ·  Respiratory Tract Diseases (385)  ·  Signs and Symptoms (372)  ·  Infant, Newborn, Diseases (338)  ·  Lung Diseases (298)

Interventions

Oxytocin (126)  ·  Misoprostol (76)  ·  Tranexamic Acid (62)  ·  carbetocin (55)  ·  Saline Solution (50)  ·  Progesterone (48)  ·  Sodium Chloride (43)  ·  Standard of Care (37)  ·  Nifedipine (28)  ·  Umbilical Cord Clamping (26)  ·  Control Groups (24)  ·  Cerclage, Cervical (19)  ·  Indomethacin (19)  ·  Music Therapy (19)  ·  Blood Specimen Collection (18)

Sponsors

Assiut University (76)  ·  Cairo University (58)  ·  Ain Shams University (43)  ·  NICHD Neonatal Research Network (41)  ·  Assistance Publique - Hôpitaux de Paris (36)  ·  Samuel Lunenfeld Research Institute, Mount Sinai Hospital (34)  ·  University of Alabama at Birmingham (31)  ·  Stanford University (25)  ·  Aswan University Hospital (24)  ·  Gynuity Health Projects (23)  ·  Christiana Care Health Services (21)  ·  University of Utah (21)  ·  University of Pennsylvania (19)  ·  Columbia University (18)  ·  University of Calgary (18)

Countries

United States (908)  ·  Turkey (Türkiye) (337)  ·  Egypt (274)  ·  France (273)  ·  Canada (193)  ·  Italy (137)  ·  Israel (124)  ·  United Kingdom (109)  ·  China (103)  ·  Spain (87)  ·  Germany (76)  ·  Switzerland (50)  ·  Pakistan (49)  ·  Belgium (46)  ·  Brazil (44)

Top investigators

Seetha Shankaran, MD (32)  ·  Barbara J. Stoll, MD (27)  ·  Richard A. Ehrenkranz, MD (25)  ·  Mrinalini Balki, MD (24)  ·  Waldemar A. Carlo, MD (21)  ·  Abhik Das, PhD (19)  ·  Edward F. Donovan, MD (18)  ·  Abbot R. Laptook, MD (17)  ·  David K. Stevenson, MD (15)  ·  James A. Lemons, MD (14)  ·  Jon E. Tyson, MD MPH (14)  ·  Sheldon B. Korones, MD (14)  ·  William Oh, MD (14)

Results publications

PMID 35947046, PMID 33232518, PMID 32609374, PMID 36996264, PMID 33305842, PMID 33006765, PMID 33169839, PMID 35921693, PMID 36453699, PMID 18275573, PMID 22086108, PMID 28235686, PMID 28456509, PMID 30741812, PMID 39162220, PMID 8598837, PMID 10429008, PMID 10835060, PMID 11430325, PMID 12114906, PMID 14510324, PMID 14520225, PMID 14523165, PMID 15060228, PMID 15286223, PMID 15507925, PMID 15520109, PMID 15547163, PMID 15713907, PMID 15741371, PMID 15741374, PMID 15930228, PMID 15956871, PMID 15973322, PMID 15995042, PMID 16000352, PMID 16027695, PMID 16107873, PMID 16143580, PMID 16322158, PMID 16396864, PMID 16467730, PMID 16507341, PMID 16549503, PMID 16585322, PMID 16598294, PMID 16615955, PMID 16647401, PMID 16769377, PMID 16818526

NIH funding

U10HD021385 (34), U10HD027880 (32), U10HD027851 (31), U10HD027853 (30), U10HD027904 (30), U10HD021364 (29), U10HD021373 (29), U10HD027856 (28), U10HD027871 (26), U10HD034216 (25), M01RR008084 (23), U10HD021397 (21), M01RR000070 (20), U10HD040689 (20), M01RR000750 (19)