119 completed, 28 unknown, 17 recruiting, 14 terminated. 210 Phase 1, 80 Phase 2.
Follow Pregnancy Complications: new trials by email Literature Review of Pregnancy Complications trials Research Report on Pregnancy Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Little Lungs Study Calfactant, Budesonide - Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome | Phase 1 / Phase 2 | Not yet recruiting | University of Wisconsin, Madison | 24 | 2027-02-01 | 2026-11-02 |
| High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants High-energy group, Standard-energy group - Extreme Prematurity, Enteral Nutrition | Phase 1 / Phase 2 | Recruiting | University of Alabama at Birmingham | 150 | 2026-09-21 | 2026-09-24 |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
| Islet Function in Gestational Diabetes Exendin 9-39 - Gestational Diabetes Mellitus | Phase 1 | Recruiting | Mayo Clinic | 90 | 2026-09-01 | 2026-09-08 |
| Dipyridamole for Early-Onset Preeclampsia: A Pilot Study of Feasibility, Pharmacokinetics, and Biological Effects Dipyridamole 75 MG - Preeclampsia (PE), Hypertension ,Pregnancy | Phase 1 / Phase 2 | Not yet recruiting | Hadassah Medical Organization | 15 | 2026-09-01 | 2026-07-31 |
| Neonatal White Matter Injury Trial (WRAP) Clemastine fumarate - White Matter Injury, Brain Injury, Fetus and Neonate | Phase 1 | Recruiting | Bridget LaMonica Ostrem, M.D., Ph.D. | 24 | 2026-07-26 | 2026-07-28 |
| Hyperemesis Gravidarum Risk Reduction With Metformin Metformin Extended Release Oral Tablet - Hyperemesis Gravidarum | Phase 1 / Phase 2 | Recruiting | University of Southern California | 224 | 2026-07-13 | 2026-07-22 |
| Pharmacokinetics and Placental Transfer of Caffeine Caffeine citrate - Preterm Labor With Preterm Delivery, Premature Birth | Phase 1 | Recruiting | Indiana University | 30 | 2026-06-01 | 2026-06-04 |
| Pharmacokinetic Study to Evaluate Safety and Tolerability of EG-101 in Healthy Female Volunteers as a Safety Lead-In for Dosing in Pregnant Women With Severe Pre-eclampsia EG-101 - Pre-eclampsia | Phase 1 | Not yet recruiting | Evergreen Therapeutics, Inc. | 24 | 2026-06-01 | 2026-01-12 |
| Tocilizumab for the Treatment of Refractory Granulomatous Lobular Mastitis Tocilizumab - Granulomatous Lobular Mastitis, Granulomatous Mastitis | Phase 1 / Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 31 | 2026-06-01 | 2026-05-19 |
| Comparison of Efficacy and Safety of Oral Versus Vaginal Misoprostol in Missed Abortion in First Trimester of Pregnancy Oral misoprostol, Misoprostol (given vaginally) - Missed Abortion | Phase 1 | Not yet recruiting | Hamna Khaliq | 100 | 2026-05-01 | 2026-04-13 |
| Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis Steroid, Antibiotic - Granulomatous Mastitis | Phase 1 / Phase 2 | Not yet recruiting | All India Institute of Medical Sciences, Bhubaneswar | 72 | 2026-03-15 | 2026-03-06 |
| PNEUMOSTEM® for Improving Respiratory Outcomes in Very Premature Infants Diagnosed With Early Pulmonary Arterial Hypertension PNEUMOSTEM® - Pulmonary Arterial Hypertension (PAH), Premature Infants | Phase 1 | Not yet recruiting | Samsung Medical Center | 12 | 2026-03-01 | 2026-01-26 |
| PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia montelukast 4 mg granule, Placebo - Bronchopulmonary Dysplasia (BPD), Premature Births | Phase 1 / Phase 2 | Recruiting | Duke University | 28 | 2026-02-23 | 2026-07-14 |
| Phase Ib/IIa Clinical Trial of SIBP-A16 Injection in Premature Infants and Full-term Infants SIBP-A16 injection, Nirsevimab, SIBP-A16 buffer solution - Respiratory Syncytial Virus (RSV) | Phase 1 / Phase 2 | Not yet recruiting | Shanghai Institute Of Biological Products | 36 | 2026-01-15 | 2026-01-23 |
| The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy Intradermal Microdialysis, Brain Blood Flow Tests, Local Heating - Gestational Diabetes Mellitus (GDM), Postpartum Women | Phase 1 | Recruiting | Anna Stanhewicz, PhD | 84 | 2025-08-22 | 2025-12-16 |
| Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH) Daily aspirin (ASA), Split dose aspirin (ASA) - Preterm Birth, Preeclampsia | Phase 1 / Phase 2 | Recruiting | Thomas Jefferson University | 400 | 2025-06-26 | 2025-07-17 |
| Dose Escalation Study of Vinpocetine in Healthy Volunteers Vinpocetine - Fetal Alcohol Spectrum Disorders | Phase 1 | Not yet recruiting | Stanford University | 20 | 2025-06-01 | 2024-10-10 |
| ROLE OF PROPHYLACTIC TRANEXAMIC ACID IN PREVENTION OF POST-PARTUM HEMORRHAGE IN ELLSCS Tranexamic Acid (TXA), Placebo - Post Partum Hemorrhage | Phase 1 | Not yet recruiting | Patel Hospital, Pakistan | 104 | 2025-06-01 | 2025-06-04 |
| Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational Diabetes Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (200 µg/d), Dietary Supplement: Oral chromium supplementation during gestational diabetes mellitus through the administration of chromium picolinate tablets (400 µg/d) - Gestational Diabetes Mellitus (GDM), Oxidative Stress | Phase 1 / Phase 2 | Not yet recruiting | University of Kasdi Merbah | 200 | 2025-05-01 | 2025-03-05 |
Showing 20 of 210. Sign in to see all of them.
Premature Birth (84) · Pre-Eclampsia (27) · HIV Infections (17) · Pregnancy Complications, Infectious (16) · Bronchopulmonary Dysplasia (15) · Postpartum Hemorrhage (15) · Obstetric Labor, Premature (11) · Depression, Postpartum (10) · Diabetes, Gestational (9) · Breast Neoplasms (6) · Fetal Alcohol Spectrum Disorders (6) · Gestational Trophoblastic Disease (6) · Hypertension, Pregnancy-Induced (6) · Carcinoma, Ovarian Epithelial (5)
Female Urogenital Diseases and Pregnancy Complications (210) · Urogenital Diseases (210) · Obstetric Labor Complications (108) · Obstetric Labor, Premature (76) · Pathological Conditions, Signs and Symptoms (52) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (43) · Pathologic Processes (39) · Genital Diseases (32) · Infections (30) · Puerperal Disorders (28) · Respiratory Tract Diseases (27) · Lung Diseases (24) · Hypertension, Pregnancy-Induced (23) · Infant, Newborn, Diseases (23)
Zidovudine (9) · Misoprostol (8) · Sodium Chloride (8) · Oxytocin (7) · Lamivudine (5) · Saline Solution (4) · Acetaminophen (3) · Budesonide (3) · Cholecalciferol (3) · GSK221149A (3) · Injections (3) · Nifedipine (3) · Acetylcysteine (2) · Aspirin (2) · Dexamethasone (2)
National Institute of Allergy and Infectious Diseases (NIAID) (17) · GlaxoSmithKline (9) · Ain Shams University (5) · Cairo University (5) · NICHD Neonatal Research Network (5) · Stanford University (5) · Mansoura University Children Hospital (4) · University of Alabama at Birmingham (4) · Centers for Disease Control and Prevention (3) · The University of Texas Medical Branch, Galveston (3) · Butler Hospital (2) · Children's Hospital Medical Center, Cincinnati (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Hadassah Medical Organization (2) · Hormozgan University of Medical Sciences (2)
United States (106) · Egypt (14) · Canada (9) · China (9) · Australia (6) · Puerto Rico (6) · Iran (5) · Israel (4) · South Korea (4) · United Kingdom (4) · Brazil (3) · Pakistan (3) · Spain (3) · Denmark (2) · Finland (2)
Barbara J. Stoll, MD (3) · Edward F. Donovan, MD (3) · Richard A. Ehrenkranz, MD (3) · Waldemar A. Carlo, MD (3) · Abbot R. Laptook, MD (2) · Abhik Das, PhD (2) · Avroy A. Fanaroff, MD (2) · Charles R. Bauer, MD (2) · Edward F. Bell, MD (2) · Grace Lim, MD, MSc (2) · Jennifer Beck, PhD (2) · Kathleen A. Kennedy, MD MPH (2) · Krisa P. Van Meurs, MD (2) · Kristi L. Watterberg, MD (2)
PMID 33305842, PMID 10379020, PMID 10467792, PMID 10908457, PMID 11502292, PMID 14600674, PMID 14657758, PMID 15209957, PMID 15342835, PMID 15713907, PMID 15774846, PMID 15814645, PMID 15954876, PMID 16015266, PMID 16136470, PMID 16148846, PMID 16220994, PMID 16325601, PMID 16581405, PMID 16842791, PMID 17197859, PMID 17634155, PMID 18055730, PMID 18474496, PMID 18846389, PMID 19432563, PMID 19919718, PMID 19943825, PMID 20009308, PMID 20068553, PMID 20338954, PMID 20375733, PMID 21091415, PMID 21865980, PMID 22251828, PMID 22336574, PMID 22495532, PMID 22540529, PMID 22818551, PMID 22882240, PMID 22935620, PMID 23089601, PMID 23150927, PMID 23340184, PMID 23587979, PMID 23650301, PMID 23673863, PMID 23997960, PMID 24191345, PMID 24218460
U10HD021364 (5), U10HD027853 (4), U10HD027904 (4), U10HD034216 (4), M01RR000080 (3), M01RR008084 (3), U10HD021373 (3), U10HD021385 (3), U10HD027851 (3), U10HD027856 (3), U10HD027871 (3), U10HD027880 (3), U10HD036790 (3), R01MH134538 (2), U10HD021397 (2)