190 completed, 60 unknown, 26 terminated, 24 recruiting. 90 Phase 4, 76 Not applicable, 60 Phase 2, 60 Phase 3, 30 Phase 1.
Follow Progesterone: new trials by email Literature Review of Progesterone trials Research Report on Progesterone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cycle-to-cycle Variability of Progesterone in the Endometrium in Patients Undergoing an Euploid Blastocyst Transfer in a Hormone Replacement Therapy (HRT) Cycle (PROMICOFET) Oestrogel® 0.75 mg (estradiol transdermal gel), Progesterone 200 mg vaginal capsules, Endometrial biopsy - Fertility, Implantation, Embryo | Phase 4 | Not yet recruiting | University Hospital, Ghent | 70 | 2026-10-01 | 2026-09-14 |
| Oral GnRH Antagonist (Linzagolix) Versus Injectable GnRH Antagonist in Controlled Ovarian Stimulation for In Vitro Fertilization: A Randomized Controlled Non-Inferiority Trial With a Concurrent Comparator Cohort Undergoing Progestin-Primed Ovarian Stimulation (PPOS) Ganirelix ; Cetrorelix, Medroxyprogesterone Acetate ; Micronized Progesterone, Linzagolix - Infertility, Female, Ovulation Induction | Not applicable | Not yet recruiting | Centro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita) | 120 | 2026-09-01 | 2026-09-30 |
| Comparing the Pharmacokinetics of a Progesterone Ring Versus a Progesterone Vaginal Insert Progesterone - Pre Term Birth | Phase 1 | Not yet recruiting | Daré Bioscience, Inc. | 60 | 2026-09-01 | 2026-05-08 |
| Azithromycin for Cerclage Prophylaxis Azithromycin Prophylaxis, Azithromycin Placebo, Cefazolin - Cervical Insufficiency | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 80 | 2026-09-01 | 2026-08-27 |
| Progesterone Supplementation After Letrozole-stimulated Insemination Progesterone - Infertility | Phase 4 | Recruiting | Kirstine Kirkegaard | 690 | 2026-08-28 | 2026-09-09 |
| Exogenous Progesterone as Ovulation Trigger Vaginal micronized progesterone - Ovulation, Ovarian Function | Phase 4 | Not yet recruiting | Instituto Valenciano de Infertilidade de Lisboa | 10 | 2026-07-01 | 2026-06-04 |
| GnRH for Luteal Support - Mechanism of Action GnRH agonist, Progesterone - GnRH Antagonist IVF Protocol, Fresh Embryo Transfer | Recruiting | Heli Alexandroni | 150 | 2026-05-18 | 2026-06-02 | |
| First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency 400mg progesterone Callavid - 2hr wear, Cyclogest 400 mg, 400mg progesterone Callavid - 3hr wear - Luteal Phase Insuffiency, Progesterone Delivery | Phase 1 | Recruiting | Calla Lily Clinical Care Ltd | 20 | 2026-04-20 | 2026-09-10 |
| Cerclage Plus Progesterone vs Progesterone Alone in Twin Short Cervix Cervical cerclage, Progesterone - Preterm | Not applicable | Recruiting | National Hospital of Obstetrics and Gynecology | 260 | 2026-04-10 | 2026-04-24 |
| Menopausal HT for Women Living With HIV (HoT) Transdermal estradiol gel, Micronized Progesterone, Placebo for estradiol gel - HIV Infection, Menopause | Phase 4 | Recruiting | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 105 | 2026-04-09 | 2026-05-22 |
| Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy Dydrogesterone 10 MG Oral Tablet, Micronized progesterone 200 MG, Transdermal estradiol - Menopausal Women, Menopausal Symptom Relief | Not applicable | Not yet recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 200 | 2026-04-01 | 2026-03-27 |
| FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural Cycles Letrozole (Aromatase Inhibitors), Choriogonadotropin alpha (r-hCG), Progesterone - Infertility Female, Frozen Embryo Transfer (FET) | Not applicable | Recruiting | University of Novi Sad | 120 | 2026-03-13 | 2026-09-29 |
| Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate - Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes | Not applicable | Enrolling by invitation | Enhanced Emirates Limited | 60 | 2026-03-12 | 2026-05-06 |
| Progesterone and Muscle Protein Synthesis in Premenopausal Women (MP4-MPS) Micronized progesterone (oral capsules), placebo capsule - Healthy Volunteers, Female | Phase 1 | Completed | McMaster University | 20 | 2026-01-01 | 2026-06-17 |
| Effect of Progesterone Administration on Severely Head Injured Patients Progesterone, The usual head trauma care - Severe Head Trauma | Phase 1 | Not yet recruiting | Assiut University | 50 | 2025-12-01 | 2025-06-25 |
| An Open-label, Randomized, Single-dose, Two-treatment, Four-period, Fully Replicate Crossover Bioequivalence Study in Healthy Female Adult Participants Under Fasting Conditions Comparing the Test Product, Prontogest Solution for IM Injection With the Reference Product, Progesterone Injection Progesterone IM of 100 mg - Bioequivalance, Post-menopause | Phase 1 | Completed | Zi Diligence Biocenter | 26 | 2025-11-10 | 2026-03-27 |
| Nintedanib for Improving Reproductive Outcomes in Adenomyosis Nintedanib, Progesterone - Adenomyosis of Uterus | Phase 3 | Not yet recruiting | Sun Yat-sen University | 328 | 2025-09-01 | 2025-09-09 |
| Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome Micronized progesterone 200 MG, Micronized Progesterone 100 MG - Turner Syndrome, Primary Ovarian Insufficiency (Poi) | Phase 4 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2025-07-31 | 2026-08-25 |
| Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency Progesterone, Estrogen Patch - Premature Ovarian Insufficiency | Phase 3 | Recruiting | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 185 | 2025-07-17 | 2026-10-21 |
| Progesterone in Gender Affirming Hormone Therapy Study Placebo, Progesterone - Transgender Women | Phase 2 | Recruiting | Emory University | 40 | 2025-05-12 | 2025-12-24 |
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