670 completed, 163 unknown, 119 recruiting, 63 not yet recruiting. 646 Not applicable, 83 Phase 4, 78 Phase 3, 76 Phase 2, 30 Phase 1.
Follow Puerperal Disorders: new trials by email Literature Review of Puerperal Disorders trials Research Report on Puerperal Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Whole-Body Hyperthermia for Mood and Anxiety Disorders Whole-Body Hyperthermia, fMRI - Postpartum Depression, Mood Disorders | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 240 | 2028-06-01 | 2026-06-23 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| Postpartum Care in the NICU Multi-Site Postpartum Doula Support in the NICU - Postpartum, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 756 | 2027-01-01 | 2026-10-14 |
| Ophthalmic Artery Doppler in the Puerperium After Hypertensive Disorders of Pregnancy (OPHELIA-PP) Hypertensive Disorders of Pregnancy, Pre-eclampsia | Not yet recruiting | University of Roma La Sapienza | 366 | 2027-01-01 | 2026-09-25 | |
| AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety Postpartum Depression (PPD), Postpartum Anxiety | Not yet recruiting | University of Hawaii | 100 | 2026-12-01 | 2026-10-21 | |
| A Web-based Intervention Program for Postpartum Depression Web-based program for postpartum depression - Postpartum Depression (PPD), Web-based Intervention | Early Phase 1 | Recruiting | Babes-Bolyai University | 30 | 2026-10-27 | 2026-10-28 |
| The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission. Doula-delivered, Nurse-coordinated postpartum support - Doula Support, Postpartum | Not applicable | Recruiting | University of South Carolina | 350 | 2026-10-21 | 2026-10-23 |
| Comparing Simulated Patients and Manikin Based Simulation in Obstetrics Trained, standardized patient, MamaAnne Patient Simulator - PPH - Postpartum Hemorrhage, Eclampsia | Not applicable | Not yet recruiting | Medical University of Vienna | 72 | 2026-10-15 | 2026-10-05 |
| Web-Based Gamification in Postpartum Hemorrhage Management Education Among Midwifery Students Web-Based Gamification Education, Online Classical Education - Hemorrhage Management Training, Gamification in Health Education | Not applicable | Not yet recruiting | Mersin University | 128 | 2026-10-01 | 2026-07-07 |
| Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms Contingency Management & Problem Solving Therapy, Usual Care - Postpartum Depression (PPD), Alcohol Use | Not applicable | Recruiting | University of Illinois at Chicago | 30 | 2026-10-01 | 2026-10-13 |
| Effect of Peripartum 40 Hz Audiovisual Stimulation on Postpartum Depression in Women Undergoing Elective Cesarean Section: A Randomized Clinical Trial 40 Hz Audiovisual Stimulation, Placebo Audiovisual Stimulation - Depression, Postpartum | Not applicable | Not yet recruiting | The First People's Hospital of Lianyungang | 204 | 2026-10-01 | 2026-09-08 |
| LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies LLM-Generated Medical Summaries - High-risk Pregnancy, Hospitalization | Not applicable | Not yet recruiting | Sheba Medical Center | 200 | 2026-10-01 | 2026-09-16 |
| Efficacy of Balloon Tamponade in Post-partum Hemorrhage Within 24 Hours After Delivery Intrauterine Balloon Tamponade - Condom Catheter - Postpartum Hemorrhage | Not yet recruiting | Aziz Fatimah Medical & Dental College, Faisalabad | 121 | 2026-10-01 | 2026-09-28 | |
| Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage Postpartum Hemorrhage, Treatment Outcome | Recruiting | University of Zurich | 380 | 2026-10-01 | 2026-10-21 | |
| HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding Embolization therapy - Hemorrhage, Gastrointestinal Hemorrhage | Not yet recruiting | Aesculap AG | 176 | 2026-09-30 | 2026-08-07 | |
| Deconstructing Maternal Burdens: Doulas and the Community Unite for Health Doula, Standard (non-enhanced) Medicaid doula support - Pregnancy, Post Partum | Not applicable | Recruiting | University of Florida | 516 | 2026-09-15 | 2026-09-28 |
| The Effects of a Caregiver-initiated Reading Intervention to Their Infant in the Neonatal Intensive Care Unit Reading Intervention - Infant Admitted to Neonatal Intensive Care Unit (NICU) | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 120 | 2026-09-14 | 2026-08-27 |
| Early Detection of Perinatal Depression With Wearable Technology Oura Ring (Photoplethysmography-based wearable ring), EmbracePlus Watch (Electrodermal activity wristband sensor) - Perinatal Depression | Not applicable | Not yet recruiting | Women's College Hospital | 10 | 2026-09-01 | 2026-08-25 |
| Treatment With Repetitive Transcranial Magnetic Stimulation in Peripartal Depression Repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation - Depression During Pregnancy, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Psychiatric University Hospital, Zurich | 60 | 2026-09-01 | 2026-08-19 |
| Multimodal Biomarkers and Precision TMS for Postpartum Depression Repetitive Transcranial Magnetic Stimulation (rTMS) - Depression, Postpartum | Not applicable | Not yet recruiting | University of Macau | 290 | 2026-09-01 | 2026-08-11 |
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Depression, Postpartum (561) · Postpartum Hemorrhage (463) · Depression (102) · Anxiety Disorders (54) · Breast Feeding (52) · Hemorrhage (30) · Psychological Well-Being (27) · Mastitis (25) · Premature Birth (24) · Uterine Inertia (23) · Depressive Disorder, Major (19) · Granulomatous Mastitis (17) · Pregnancy Complications (16) · Motor Activity (15)
Female Urogenital Diseases and Pregnancy Complications (1121) · Urogenital Diseases (1121) · Pregnancy Complications (1106) · Mental Disorders (555) · Depressive Disorder (551) · Mood Disorders (549) · Pathological Conditions, Signs and Symptoms (534) · Pathologic Processes (489) · Obstetric Labor Complications (486) · Uterine Hemorrhage (460) · Hemorrhage (434) · Behavior (208) · Behavioral Symptoms (108) · Signs and Symptoms (68)
Oxytocin (105) · Misoprostol (63) · carbetocin (55) · Tranexamic Acid (51) · Sodium Chloride (21) · Saline Solution (19) · Standard of Care (13) · Therapeutics (13) · Cognitive Behavioral Therapy (11) · brexanolone (11) · Ketamine (10) · Ergonovine (8) · Control Groups (7) · Esketamine (7) · Exercise (7)
Samuel Lunenfeld Research Institute, Mount Sinai Hospital (34) · Gynuity Health Projects (23) · Cairo University (22) · Assiut University (16) · McMaster University (16) · Northwestern University (14) · Aswan University Hospital (12) · Assistance Publique - Hôpitaux de Paris (11) · Columbia University (9) · Stanford University (9) · Ain Shams University (8) · Women and Infants Hospital of Rhode Island (8) · Brigham and Women's Hospital (7) · Istanbul University - Cerrahpasa (7) · Massachusetts General Hospital (7)
United States (294) · Turkey (Türkiye) (108) · Canada (93) · Egypt (83) · France (50) · China (47) · Pakistan (35) · Israel (23) · Spain (21) · United Kingdom (21) · Italy (18) · India (16) · Switzerland (15) · Denmark (13) · Hong Kong (9)
Mrinalini Balki, MD (24) · Beverly Winikoff, MD, MPH (10) · Jill Durocher (9) · Ryan Van Lieshout, MD, PhD (6) · Jose Carvalho, MD (5) · Rasha Dabash, MPH (5) · Ahmed Maged (4) · Darius Tandon, PhD (4) · Dong-Xin Wang, MD, PhD (4) · Martha G Welch, MD (4) · Sona Dimidjian, PhD (4) · Ayisha Diop, MPH (3) · Caron Zlotnick, PhD (3)
PMID 33232518, PMID 32609374, PMID 42383885, PMID 33169839, PMID 32987448, PMID 33078388, PMID 34286512, PMID 28456509, PMID 33181049, PMID 39162220, PMID 17027730, PMID 22581378, PMID 24880136, PMID 25374288, PMID 27227751, PMID 29718920, PMID 30119704, PMID 30177236, PMID 32944940, PMID 34232578, PMID 36737079, PMID 37158447, PMID 37713322, PMID 39010232, PMID 39443446, PMID 10137741, PMID 10467792, PMID 10522604, PMID 10908457, PMID 11181139, PMID 11207490, PMID 11502292, PMID 11864681, PMID 12171026, PMID 12727395, PMID 12738159, PMID 14313451, PMID 14600674, PMID 14768311, PMID 15227649, PMID 15295368, PMID 15339775, PMID 15669988, PMID 15954876, PMID 16108235, PMID 1623693, PMID 16309682, PMID 16319245, PMID 16390366, PMID 16502488
2023 (4), 2009 (2), 2017 (2), R01MH134538 (2), R21HD101786 (2), R21MD011320 (2), R34MH083866 (2), R61MH118405 (2), 1UG3HL165064-01 (1), 2005 (1), 2008 (1), 2014 (1), 2016 (1), 2018 (1), 2025 (1)