3959 completed, 1481 unknown, 829 recruiting, 384 not yet recruiting. 3472 Not applicable, 507 Phase 3, 464 Phase 2, 450 Phase 4, 210 Phase 1.
Follow Pregnancy Complications: new trials by email Literature Review of Pregnancy Complications trials Research Report on Pregnancy Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Whole-Body Hyperthermia for Mood and Anxiety Disorders Whole-Body Hyperthermia, fMRI - Postpartum Depression, Mood Disorders | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 240 | 2028-06-01 | 2026-06-23 |
| Oral Sodium Bicarbonate for the Prevention of Labour Dystocia oral sodium bicarbonate - Labour Dystocia | Not applicable | Not yet recruiting | Liz Darling | 200 | 2027-10-01 | 2026-10-23 |
| Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus Semaglutide (Wegovy) weekly injection - Gestational Diabetes Mellitus (GDM), Metabolic Syndrome | Phase 2 / Phase 3 | Not yet recruiting | University of Massachusetts, Worcester | 226 | 2027-09-01 | 2026-09-28 |
| Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy Loss 200mg mifepristone and 800mg misoprostol - Early Pregnancy Loss | Phase 3 | Not yet recruiting | University of Pennsylvania | 1000 | 2027-07-01 | 2026-10-09 |
| A Randomized Trial to Reduce Blood Pressure at One Year Postpartum After Preeclampsia The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs). - Adverse Pregnancy Outcomes, Cardiovascular Diseases | Not applicable | Not yet recruiting | Maternal-Infantil Vall d´Hebron Hospital | 150 | 2027-06-01 | 2026-10-23 |
| Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention Clinician notification of elevated preeclampsia risk - Preeclampsia, Hypertensive Disorders of Pregnancy (HDP) | Not applicable | Not yet recruiting | Massachusetts General Hospital | 1000 | 2027-05-01 | 2026-05-29 |
| REmote Physical ACtivity Intervention for High Blood Pressure Postpartum Patient Portal Messaging, FitBit EHR Linkage - Hypertension (HTN), Hypertension ,Pregnancy | Not applicable | Not yet recruiting | Northwestern University | 60 | 2027-04-01 | 2026-09-17 |
| Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders Ravulizumab - Preeclampsia | Phase 2 | Recruiting | Mayo Clinic | 14 | 2027-04-01 | 2026-10-22 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism | Not yet recruiting | University Hospital, Lille | 1600 | 2027-03-01 | 2026-05-22 | |
| Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial Chinstrap - Apnea of Prematurity, Intermittent Hypoxemia | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 20 | 2027-01-15 | 2026-10-27 |
| e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss e-Perinatal Butterfly, Standard routine maternal care - Depressive Symptoms, Perinatal Loss | Not applicable | Not yet recruiting | University of Seville | 60 | 2027-01-12 | 2026-10-30 |
| Eye Tracking and Autism in Former Preterm Infants Eye-tracking device - Autism, Prematurity | Not applicable | Not yet recruiting | Indiana University | 40 | 2027-01-04 | 2026-08-14 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care Lateral, Prone, Incubator care - Kangaroo Care, Premature Infant | Not applicable | Not yet recruiting | Hospital Universitario 12 de Octubre | 314 | 2027-01-01 | 2026-03-16 |
| Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells - Extremely Premature Infant, Anemia Neonatal | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 176 | 2027-01-01 | 2026-03-31 |
| Postpartum Care in the NICU Multi-Site Postpartum Doula Support in the NICU - Postpartum, Postpartum Depression (PPD) | Not applicable | Not yet recruiting | Children's Hospital of Philadelphia | 756 | 2027-01-01 | 2026-10-14 |
| Ophthalmic Artery Doppler in the Puerperium After Hypertensive Disorders of Pregnancy (OPHELIA-PP) Hypertensive Disorders of Pregnancy, Pre-eclampsia | Not yet recruiting | University of Roma La Sapienza | 366 | 2027-01-01 | 2026-09-25 | |
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| Early Nutrition and Heart Structure and Function in Preterm Infants During the First Year of Life echocardiography - Cardiac Abnormalities, Nutrient Intake | Not yet recruiting | Assiut University | 117 | 2026-12-01 | 2026-10-23 |
Showing 20 of 7535. Sign in to see all of them.
Premature Birth (2526) · Pre-Eclampsia (882) · Diabetes, Gestational (829) · Depression, Postpartum (561) · Postpartum Hemorrhage (463) · Hypertension, Pregnancy-Induced (262) · Fetal Growth Retardation (257) · Obstetric Labor, Premature (228) · Abortion, Spontaneous (212) · Pelvic Floor Disorders (212) · Bronchopulmonary Dysplasia (158) · Placenta Accreta (144) · Obesity (141) · Breast Feeding (140)
Female Urogenital Diseases and Pregnancy Complications (7534) · Urogenital Diseases (7534) · Obstetric Labor Complications (3519) · Obstetric Labor, Premature (2426) · Pathological Conditions, Signs and Symptoms (2120) · Pathologic Processes (1320) · Nutritional and Metabolic Diseases (1100) · Puerperal Disorders (1082) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (976) · Endocrine System Diseases (940) · Metabolic Diseases (933) · Signs and Symptoms (913) · Glucose Metabolism Disorders (879) · Diabetes Mellitus (804)
Oxytocin (138) · Misoprostol (134) · Aspirin (73) · Saline Solution (72) · Standard of Care (67) · Progesterone (65) · Metformin (63) · Tranexamic Acid (63) · Sodium Chloride (60) · Blood Specimen Collection (59) · carbetocin (57) · Exercise (49) · Nifedipine (47) · Control Groups (45) · Ultrasonography (38)
Assiut University (148) · Cairo University (106) · Ain Shams University (77) · Assistance Publique - Hôpitaux de Paris (76) · University of Pennsylvania (50) · Stanford University (45) · University of Alabama at Birmingham (45) · NICHD Neonatal Research Network (44) · The University of Texas Health Science Center, Houston (41) · Gynuity Health Projects (40) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (38) · Northwestern University (37) · Brigham and Women's Hospital (35) · Washington University School of Medicine (35) · Aswan University Hospital (34)
United States (2008) · Turkey (Türkiye) (616) · Egypt (493) · France (469) · Canada (371) · China (317) · United Kingdom (242) · Italy (230) · Israel (224) · Spain (214) · Pakistan (134) · Germany (124) · Denmark (121) · Brazil (110) · India (90)
Seetha Shankaran, MD (35) · Barbara J. Stoll, MD (28) · Richard A. Ehrenkranz, MD (27) · Mrinalini Balki, MD (24) · Waldemar A. Carlo, MD (23) · Edward F. Donovan, MD (20) · Abhik Das, PhD (19) · Abbot R. Laptook, MD (18) · Ahmed Maged, MD (18) · David K. Stevenson, MD (16) · Sheldon B. Korones, MD (16) · Avroy A. Fanaroff, MD (15) · James A. Lemons, MD (15)
PMID 35947046, PMID 36996264, PMID 33232518, PMID 32609374, PMID 37815037, PMID 42383885, PMID 32748394, PMID 33305842, PMID 34061352, PMID 33006765, PMID 33169839, PMID 35921693, PMID 32358837, PMID 34286512, PMID 36453699, PMID 32378735, PMID 32987448, PMID 33078388, PMID 33779986, PMID 18275573, PMID 22086108, PMID 23356673, PMID 28235686, PMID 28456509, PMID 28657417, PMID 29370047, PMID 29872859, PMID 30373146, PMID 30741812, PMID 33181049, PMID 34529073, PMID 39147903, PMID 39162220, PMID 39704322, PMID 8598837, PMID 10429008, PMID 10802492, PMID 10835060, PMID 11430325, PMID 12114906, PMID 14510324, PMID 14520225, PMID 14523165, PMID 15060228, PMID 15286223, PMID 15507925, PMID 15520109, PMID 15547163, PMID 15713907, PMID 15717289
U10HD021385 (37), U10HD027880 (35), U10HD021364 (32), U10HD027851 (32), U10HD027853 (32), U10HD027904 (32), U10HD021373 (31), U10HD027856 (30), U10HD027871 (28), U10HD034216 (28), M01RR008084 (25), U10HD021397 (23), M01RR000070 (22), U10HD040689 (22), M01RR000750 (21)