180 completed, 67 unknown, 44 recruiting, 27 terminated. 107 Not applicable, 67 Phase 2, 45 Phase 3, 40 Phase 1, 18 Phase 4.
Follow Bronchopulmonary Dysplasia: new trials by email Literature Review of Bronchopulmonary Dysplasia trials Research Report on Bronchopulmonary Dysplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells - Extremely Premature Infant, Anemia Neonatal | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 176 | 2027-01-01 | 2026-03-31 |
| Continued Pressure for Alveolar Protection (CPAP Trial) CPAP, Nasal Cannula - Bronchopulmonary Dysplasia (BPD) | Not applicable | Recruiting | NICHD Neonatal Research Network | 860 | 2026-11-05 | 2026-07-14 |
| National Surveillance and Prevention of Neonatal VAP Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD) | Not yet recruiting | University of Alberta | 1500 | 2026-10-01 | 2026-06-25 | |
| Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature Infants Bronchopulmonary Dysplasia | Not yet recruiting | Huiyi Li | 100 | 2026-10-01 | 2026-09-30 | |
| Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data Artificial Intelligence-Based Risk Prediction - Bronchopulmonary Dysplasia | Not yet recruiting | Konya City Hospital | 108 | 2026-10-01 | 2026-07-09 | |
| Parent Perceptions of OptiPAP Junior Nasal CPAP interface: OptiPAP Junior, Nasal CPAP interface: FlexiTrunk - Bronchopulmonary Dysplasia (BPD), Preterm Birth Complication | Not applicable | Not yet recruiting | Sharp HealthCare | 60 | 2026-10-01 | 2026-09-23 |
| Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants higher oxygen saturation target using Nellcor pulse oximetry sensors, lower oxygen saturation target using Nellcor pulse oximetry sensors - Bronchopulmonary Dysplasia, Pulmonary Hypertension | Not applicable | Recruiting | University of Alabama at Birmingham | 39 | 2026-09-22 | 2026-10-06 |
| High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants High-energy group, Standard-energy group - Extreme Prematurity, Enteral Nutrition | Phase 1 / Phase 2 | Recruiting | University of Alabama at Birmingham | 150 | 2026-09-21 | 2026-09-24 |
| Predictors of Prolonged Mechanical Ventilation in Preterm Infants Premature Birth, Respiration Failure | Not yet recruiting | Assiut University | 100 | 2026-09-10 | 2026-09-16 | |
| Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants Bronchopulmonary Dysplasia | Not yet recruiting | Medical University of Vienna | 140 | 2026-09-01 | 2026-08-18 | |
| 129Xe MRI in Pediatric Population With BPD MagniXene, hyperpolarized 129Xe MRI - Bronchopulmonary Dysplasia | Phase 1 | Withdrawn | Xemed LLC | 2026-08-01 | 2026-02-05 | |
| Ventilator Pressure and Optimization of Compliance and Hemodynamics Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP - Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia | Not applicable | Recruiting | University of Alabama at Birmingham | 24 | 2026-08-01 | 2026-05-11 |
| Pharmacokinetics and Placental Transfer of Caffeine Caffeine citrate - Preterm Labor With Preterm Delivery, Premature Birth | Phase 1 | Recruiting | Indiana University | 30 | 2026-06-01 | 2026-06-04 |
| OCTA Evaluation of Retinal Vascularization in Preterm Infants With or Without Bronchopulmonary Dysplasia OCT Angiography - Bronchopulmonary Dysplasia | Not applicable | Not yet recruiting | Centre Hospitalier Intercommunal Creteil | 56 | 2026-06-01 | 2026-06-15 |
| Pressure Targeting During High Flow Therapy in Premature Infants Pressure Targeted High Flow, CPAP - Preterm Infants, Respiratory Distress Syndrome (Neonatal) | Phase 2 | Not yet recruiting | University of Texas at Austin | 78 | 2026-05-01 | 2026-02-18 |
| Lipid Infusions to Optimize Nutrition Trial SOLE, MOLE - Bronchopulmonary Dysplasia, Neurodevelopmental Impairment | Phase 2 | Recruiting | The University of Texas Health Science Center, Houston | 230 | 2026-04-29 | 2026-08-06 |
| Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below intravenous immunoglobulin - Bronchopulmonary Dysplasia | Phase 2 | Recruiting | International Peace Maternity and Child Health Hospital | 29 | 2026-04-23 | 2026-07-23 |
| Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively? Betamethasone - Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD) | Phase 2 | Not yet recruiting | Khang Nguyen | 100 | 2026-04-01 | 2026-03-03 |
| Impact of the Early Life Virome Development on Bronchopulmonary Dysplasia in Preterm Neonates Viral metagenomics and metatranscriptomics analysis of oropharyngeal and stool samples - Bronchopulmonary Dysplasia (BPD) | Not yet recruiting | Hospices Civils de Lyon | 40 | 2026-04-01 | 2026-03-23 | |
| PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm Infants Nasal swab, blood sampling, Mother milk sampling - Bronchopulmonary Dysplasia, Preterm Infant Development | Not applicable | Not yet recruiting | University Hospital, Caen | 270 | 2026-03-01 | 2026-02-13 |
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Premature Birth (152) · Respiratory Distress Syndrome (35) · Lung Diseases (22) · Retinopathy of Prematurity (19) · Enterocolitis, Necrotizing (13) · Hypertension, Pulmonary (13) · Respiratory Distress Syndrome, Newborn (13) · Infant, Newborn, Diseases (11) · Infant, Premature, Diseases (11) · Ductus Arteriosus, Patent (10) · Asthma (9) · Respiratory Aspiration (9) · Respiratory Insufficiency (8) · Apnea (7)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (358) · Lung Injury (354) · Respiratory Tract Diseases (352) · Ventilator-Induced Lung Injury (351) · Infant, Newborn, Diseases (347) · Infant, Premature, Diseases (347) · Lung Diseases (336) · Female Urogenital Diseases and Pregnancy Complications (156) · Urogenital Diseases (156) · Pregnancy Complications (155) · Obstetric Labor Complications (152) · Obstetric Labor, Premature (151) · Respiration Disorders (68) · Pathological Conditions, Signs and Symptoms (67) · Pathologic Processes (46)
Budesonide (11) · Saline Solution (11) · Azithromycin (7) · Continuous Positive Airway Pressure (7) · Sodium Chloride (6) · Hydrocortisone (5) · poractant alfa (5) · Dexamethasone (4) · Ibuprofen (4) · Surface-Active Agents (4) · caffeine citrate (4) · calfactant (4) · Air (3) · Albuterol (3) · Beclomethasone (3)
NICHD Neonatal Research Network (14) · Children's Hospital of Philadelphia (10) · University of Alabama at Birmingham (8) · Medipost Co Ltd. (6) · Centre Hospitalier Intercommunal Creteil (5) · Copenhagen University Hospital, Rigshospitalet (5) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (5) · Indiana University (5) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Boston Children's Hospital (4) · Children's Hospital of Chongqing Medical University (4) · Hospices Civils de Lyon (4) · National Center for Research Resources (NCRR) (4) · Alexandria University (3) · Assistance Publique - Hôpitaux de Paris (3)
United States (145) · China (32) · Canada (30) · France (23) · Italy (16) · Turkey (Türkiye) (13) · United Kingdom (13) · Netherlands (10) · South Korea (9) · Spain (9) · Australia (8) · Belgium (8) · Germany (8) · Austria (6) · Israel (6)
Barbara J. Stoll, MD (9) · Seetha Shankaran, MD (9) · Richard A. Ehrenkranz, MD (8) · Waldemar A. Carlo, MD (7) · Abhik Das, PhD (6) · Charles R. Bauer, MD (6) · Edward F. Donovan, MD (6) · Abbot R. Laptook, MD (5) · David K. Stevenson, MD (5) · Jon E. Tyson, MD MPH (5) · Ronald N. Goldberg, MD (5) · Avroy A. Fanaroff, MD (4) · Bradley Yoder, MD (4) · Brenda B. Poindexter, MD MS (4) · Dale L. Phelps, MD (4)
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U10HD027853 (11), U10HD021364 (10), U10HD021373 (10), U10HD021385 (10), U10HD027851 (10), U10HD027880 (10), U10HD027856 (9), U10HD027871 (9), U10HD027904 (9), U10HD034216 (9), M01RR008084 (8), U10HD021397 (8), M01RR000750 (6), M01RR000070 (5), M01RR000997 (5)