252 completed, 94 unknown, 29 terminated, 14 recruiting. 138 Not applicable, 109 Phase 4, 79 Phase 3, 66 Phase 2, 17 Phase 1.
Follow Misoprostol: new trials by email Literature Review of Misoprostol trials Research Report on Misoprostol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy Loss 200mg mifepristone and 800mg misoprostol - Early Pregnancy Loss | Phase 3 | Not yet recruiting | University of Pennsylvania | 1000 | 2027-07-01 | 2026-10-09 |
| Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone · Misoprostol + letrozole, misoprostol alone - Abortion Induced Complicated, Abortion | Phase 1 / Phase 2 | Not yet recruiting | Sohag University | 80 | 2026-08-01 | 2026-08-17 |
| Combined Misoprostol and Cervical Balloon vs Misoprostol Alone for Induction on the First Day in Primiparas Misoprostol, Misoprostol plus Cervical Balloon - Primiparous Women | Phase 4 | Not yet recruiting | Peking University First Hospital | 220 | 2026-06-30 | 2026-07-08 |
| Period Pills for Menstrual Regulation: A New Reproductive Health Option Mifepristone + Misoprostol - Menstrual Regulation, Menstrual Health Intervention | Phase 4 | Recruiting | University of California, San Francisco | 100 | 2026-06-22 | 2026-09-02 |
| Impact of Standardization on Outcomes Following Cervical Ripening Cervical Ripening with a double balloon catheter only, Cervical ripening with a double balloon catheter plus misoprostol, Usual-care control group - Pregnancy | Phase 2 / Phase 3 | Not yet recruiting | Indiana University | 1158 | 2026-06-01 | 2026-05-08 |
| Cervical Ripening Balloon Compared With Vaginal Misoprostol for Cervical Ripening in Obese Woman at Term Cervical folleys, Misoprostol - Cervical Ripening | Not applicable | Active not recruiting | HUDDA Ahmad | 108 | 2026-05-01 | 2026-07-06 |
| Comparison of Efficacy and Safety of Oral Versus Vaginal Misoprostol in Missed Abortion in First Trimester of Pregnancy Oral misoprostol, Misoprostol (given vaginally) - Missed Abortion | Phase 1 | Not yet recruiting | Hamna Khaliq | 100 | 2026-05-01 | 2026-04-13 |
| Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention Carbetocin 100 Microgram/mL Solution for Injection, Misoprostol - Postpartum Complication, Postpartum Hemorrhage | Not applicable | Not yet recruiting | Western Galilee Hospital-Nahariya | 146 | 2026-01-31 | 2026-01-20 |
| Office Hysteroscopy in Postmenopausal Women: A Randomized Trial of Cervical Preparation Strategies No Cervical Preparation, Misoprostol ( Cytotec) 200 microgram a tablet, Vaginal Estrogen (7-Day Regimen) - Postmenopausal Women, Intrauterine Diseases | Not applicable | Recruiting | Faculty of Medicine of Tunis | 120 | 2026-01-02 | 2026-10-16 |
| Comparison of Vaginal PGE2 (Dinoprostone) and Vaginal Misoprostol for Induction of Labour in Primigravid Term Pregnancy Misoprostol, Dinoprostone 3 mg - Labor, Induced, Term Pregnancy | Not applicable | Active not recruiting | Mayo Hospital Lahore | 240 | 2025-10-29 | 2026-04-30 |
| Intravenous Dexamethasone for Inducing Labor in Women With Term Pregnancy and Pre-Labour Rupture of Membranes Dexamethasone, Prostaglandin E1, Normal Saline - Rupture of Membranes Prior to Onset of Labor, Induction of Labor | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-31 |
| Letrozole Plus Misoprostol Versus Misoprostol Only in Induction of Missed Abortion Letrozole + Misoprostol, Misoprostol - Letrozole, Misoprostol | Not applicable | Completed | Sohag University | 400 | 2025-06-14 | 2026-06-09 |
| Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage Misoprostol (given vaginally), Letrozole 5 mg, Placebo - Miscarriage in First Trimester, Missed Miscarriage | Phase 4 | Recruiting | Nishtar Medical University | 92 | 2025-05-13 | 2025-09-08 |
| Effect of Dexamethasone on Labour Induction in Term Pregnancies Dexamethasone (Decadron) 8mg IM injection, Misoprostol 25 mcg, Both Misoprostol 25 mcg & Dexamethasone 8mg IM injection - Labor Induction | Early Phase 1 | Recruiting | Cairo University | 150 | 2025-05-01 | 2025-08-07 |
| Surgical vs. Medical Abortion on Sexual Function After Early Pregnancy Loss mifepristone and misoprostol, Vacuum Aspiration - Early Pregnancy Loss, Abortion, Spontaneous | Not applicable | Completed | Harran University | 88 | 2025-04-01 | 2026-06-12 |
| Prevention of HEMOrhagic Risk in Upper MYOmeCTomy by Use of Misoprostol. myomectomy with placebo, myomectomy with misoprostol - Myoma;Uterus, Myomectomy; Surgical Blood Loss | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 80 | 2025-03-12 | 2025-09-24 |
| Use Misoprostol to Optimize Prevention of Cervical Cancer Placebo, Misoprostol - Cervical Cancers | Not applicable | Recruiting | University of Alabama at Birmingham | 420 | 2025-02-25 | 2026-08-31 |
| Sublingual Misoprostol Versus No Cervical Priming Before Hysteroscopic Resection of Symptomatic Uterine Niches Misoprostol 200mcg Tab, Placebo tab, Hysteroscopic resection of uterine niche - Scar Niche, Abnormal Uterine Bleeding | Not applicable | Completed | Benha University | 56 | 2025-02-11 | 2025-12-16 |
| Foley Balloon for Cervical Preparation Before Dilation and Evacuation Foley Balloon Catheter, Misoprostol, Laminaria - Abortion, Second Trimester, Abortion, Medical | Not applicable | Recruiting | Stony Brook University | 102 | 2025-02-10 | 2026-04-30 |
| Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor Misoprostol, Foley catheter - Labor | Not applicable | Completed | Muhammad Aamir Latif | 76 | 2025-02-01 | 2026-02-18 |
Showing 20 of 409. Sign in to see all of them.
Postpartum Hemorrhage (63) · Abortion, Spontaneous (20) · Hemorrhage (18) · Abortion, Missed (17) · Abortion, Incomplete (10) · Blood Loss, Surgical (9) · Dilatation, Pathologic (8) · Fetal Membranes, Premature Rupture (8) · Myofibroma (6) · Pre-Eclampsia (6) · Neoplasm Metastasis (5) · Obesity (5) · Uterine Inertia (5) · Fetal Death (4) · Leiomyoma (4)
Gynuity Health Projects (51) · Cairo University (29) · Ain Shams University (25) · Assiut University (14) · Aswan University Hospital (13) · Ain Shams Maternity Hospital (8) · Stanford University (6) · Montefiore Medical Center (5) · University of Pennsylvania (5) · Aljazeera Hospital (4) · Hawler Medical University (4) · The University of Hong Kong (4) · University of Pittsburgh (4) · Wolfson Medical Center (4) · Zagazig University (4)
Egypt (117) · United States (82) · Pakistan (17) · Israel (13) · India (10) · Turkey (Türkiye) (10) · France (9) · Vietnam (9) · Brazil (7) · Sweden (7) · Tunisia (6) · Canada (5) · Ecuador (5) · Iran (5) · Iraq (5)
Beverly Winikoff, MD, MPH (24) · Jill Durocher (7) · Rasha Dabash, MPH (6) · Jennifer Blum, MPH (5) · Ahmed Maged (3) · Ayisha Diop, MPH (3) · Dina Abbas, MPH (3) · Hillary Bracken, PhD (3) · Mohamed S. Sweed, MD (3) · Mohammed A Taymour, MD (3) · Anwar H Nassar, MD (2) · Beverly Winikoff (2)
PMID 36996264, PMID 33232518, PMID 34061352, PMID 21527040, PMID 34155622, PMID 17027730, PMID 20542898, PMID 23150927, PMID 10472877, PMID 10648742, PMID 10863541, PMID 10960643, PMID 11146149, PMID 11194687, PMID 11207490, PMID 11284645, PMID 11303205, PMID 11336776, PMID 11563466, PMID 12013166, PMID 12648175, PMID 12738159, PMID 14749647, PMID 15121558, PMID 1554660, PMID 15802392, PMID 16108235, PMID 16125041, PMID 16305563, PMID 16309682, PMID 16318611, PMID 16437525, PMID 1656970, PMID 16934269, PMID 17012482, PMID 17157102, PMID 17400850, PMID 17516956, PMID 17961568, PMID 18165400, PMID 18555814, PMID 18718007, PMID 19187376, PMID 19243750, PMID 19616358, PMID 19757270, PMID 19955104, PMID 20060161, PMID 20060162, PMID 20129334
2015 (2), 2009 (1), R01CA279021 (1), R01HD071920 (1), U01HD042372 (1), U01TR002398 (1)