418 completed, 127 unknown, 78 recruiting, 59 terminated. 273 Not applicable, 114 Phase 2, 84 Phase 3, 59 Phase 1, 42 Phase 4.
Follow Infant, Premature, Diseases: new trials by email Literature Review of Infant, Premature, Diseases trials Research Report on Infant, Premature, Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Speed of Lung Inflation During Ventilation of Extremely Preterm Infants Long PRT, Short PRT - Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 68 | 2027-02-01 | 2026-06-24 |
| Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial Chinstrap - Apnea of Prematurity, Intermittent Hypoxemia | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 20 | 2027-01-15 | 2026-10-26 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia Investigational Combination Product - Periventricular Leukomalacia, White Matter Disease | Early Phase 1 | Withdrawn | MGAM LLC | 2027-01-01 | 2025-07-22 | |
| Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells - Extremely Premature Infant, Anemia Neonatal | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 176 | 2027-01-01 | 2026-03-31 |
| Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system - Retinopathy of Prematurity (ROP) | Not applicable | Recruiting | Duke University | 175 | 2026-12-01 | 2026-09-17 |
| Continued Pressure for Alveolar Protection (CPAP Trial) CPAP, Nasal Cannula - Bronchopulmonary Dysplasia (BPD) | Not applicable | Recruiting | NICHD Neonatal Research Network | 860 | 2026-11-05 | 2026-07-14 |
| Elevated Midline Positioning During Diaper Change in Preterm Infants 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change - Infant, Premature, Diseases, Premature Birth of Newborn | Not applicable | Not yet recruiting | Akdeniz University | 80 | 2026-11-01 | 2026-10-13 |
| Effect of Automated Oxygen Control on Early-childhood Lung Mechanics Forced oscillometry technique - Prematurity, Respiratory Distress Neonatal | Not yet recruiting | King's College Hospital NHS Trust | 60 | 2026-10-12 | 2026-10-14 | |
| National Surveillance and Prevention of Neonatal VAP Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD) | Not yet recruiting | University of Alberta | 1500 | 2026-10-01 | 2026-06-25 | |
| Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature Infants Bronchopulmonary Dysplasia | Not yet recruiting | Huiyi Li | 100 | 2026-10-01 | 2026-09-30 | |
| Noninvasive High Frequency Oscillatory Ventilation Versus Nasal Intermittent Mandatory Ventilation for Respiratory Distress Syndrome in Preterm Neonates Noninvasive High Frequency Oscillatory Ventilation, Nasal Intermittent Mandatory Ventilation - Respiratory Distress Syndrome (RDS), Newborn | Not applicable | Not yet recruiting | Aga Khan University | 158 | 2026-10-01 | 2026-09-23 |
| Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data Artificial Intelligence-Based Risk Prediction - Bronchopulmonary Dysplasia | Not yet recruiting | Konya City Hospital | 108 | 2026-10-01 | 2026-07-09 | |
| Parent Perceptions of OptiPAP Junior Nasal CPAP interface: OptiPAP Junior, Nasal CPAP interface: FlexiTrunk - Bronchopulmonary Dysplasia (BPD), Preterm Birth Complication | Not applicable | Not yet recruiting | Sharp HealthCare | 60 | 2026-10-01 | 2026-09-23 |
| Ventilator Pressure and Optimization of Compliance and Hemodynamics Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP - Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia | Not applicable | Recruiting | University of Alabama at Birmingham | 24 | 2026-10-01 | 2026-10-26 |
| Chest Ultrasound as Diagnostic and Prognostic Tool in Neonatal RDS Respiratory Distress Syndrome, Newborn, Neonatal Respiratory Distress | Not yet recruiting | Assiut University | 82 | 2026-09-28 | 2026-10-15 | |
| Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants higher oxygen saturation target using Nellcor pulse oximetry sensors, lower oxygen saturation target using Nellcor pulse oximetry sensors - Bronchopulmonary Dysplasia, Pulmonary Hypertension | Not applicable | Recruiting | University of Alabama at Birmingham | 39 | 2026-09-22 | 2026-10-06 |
| High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants High-energy group, Standard-energy group - Extreme Prematurity, Enteral Nutrition | Phase 1 / Phase 2 | Recruiting | University of Alabama at Birmingham | 150 | 2026-09-21 | 2026-09-24 |
| Predictors of Prolonged Mechanical Ventilation in Preterm Infants Premature Birth, Respiration Failure | Not yet recruiting | Assiut University | 100 | 2026-09-10 | 2026-09-16 | |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
Showing 20 of 773. Sign in to see all of them.
Bronchopulmonary Dysplasia (360) · Premature Birth (274) · Retinopathy of Prematurity (167) · Respiratory Distress Syndrome, Newborn (122) · Respiratory Distress Syndrome (79) · Leukomalacia, Periventricular (40) · Transient Tachypnea of the Newborn (36) · Hyaline Membrane Disease (25) · Lung Diseases (25) · Pain (25) · Infant, Newborn, Diseases (18) · Enterocolitis, Necrotizing (17) · Hypertension, Pulmonary (17) · Respiratory Aspiration (17)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (773) · Infant, Newborn, Diseases (755) · Respiratory Tract Diseases (528) · Lung Diseases (504) · Lung Injury (362) · Ventilator-Induced Lung Injury (353) · Female Urogenital Diseases and Pregnancy Complications (286) · Urogenital Diseases (286) · Pregnancy Complications (283) · Obstetric Labor Complications (273) · Obstetric Labor, Premature (272) · Respiration Disorders (240) · Pathological Conditions, Signs and Symptoms (187) · Eye Diseases (164)
Saline Solution (18) · Budesonide (12) · Continuous Positive Airway Pressure (12) · Bevacizumab (11) · Ranibizumab (10) · Sodium Chloride (10) · poractant alfa (10) · Control Groups (8) · Azithromycin (7) · Dexamethasone (7) · Ibuprofen (6) · Propranolol (6) · Echocardiography (5) · Furosemide (5) · Glucose (5)
NICHD Neonatal Research Network (22) · Children's Hospital of Philadelphia (14) · Ain Shams University (11) · University of Alabama at Birmingham (11) · Assistance Publique - Hôpitaux de Paris (8) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (8) · Duke University (8) · Indiana University (6) · Medipost Co Ltd. (6) · University of Zurich (6) · Akdeniz University (5) · Aristotle University Of Thessaloniki (5) · Centre Hospitalier Intercommunal Creteil (5) · Children's Hospital of Chongqing Medical University (5) · Copenhagen University Hospital, Rigshospitalet (5)
United States (256) · Turkey (Türkiye) (70) · Canada (51) · China (50) · France (49) · Italy (38) · United Kingdom (31) · Egypt (27) · Germany (23) · Spain (21) · Belgium (17) · Poland (17) · Israel (16) · Netherlands (16) · Sweden (16)
Seetha Shankaran, MD (16) · Barbara J. Stoll, MD (13) · Richard A. Ehrenkranz, MD (13) · Edward F. Donovan, MD (11) · Waldemar A. Carlo, MD (10) · David K. Stevenson, MD (9) · Sheldon B. Korones, MD (9) · Abhik Das, PhD (8) · Avroy A. Fanaroff, MD (8) · Charles R. Bauer, MD (8) · James A. Lemons, MD (8) · William Oh, MD (8) · Jon E. Tyson, MD MPH (7) · Abbot R. Laptook, MD (6) · Krisa P. Van Meurs, MD (6)
PMID 11401896, PMID 1388792, PMID 16009843, PMID 413500, PMID 16763218, PMID 18317237, PMID 18383112, PMID 18841536, PMID 19647838, PMID 20180736, PMID 20439601, PMID 20472939, PMID 20539253, PMID 22025591, PMID 22137670, PMID 22222548, PMID 22337229, PMID 22526637, PMID 23166334, PMID 24094879, PMID 24508444, PMID 24657120, PMID 24871971, PMID 24951077, PMID 25157725, PMID 25496504, PMID 25534356, PMID 25712598, PMID 25868788, PMID 26351971, PMID 27187300, PMID 29519879, PMID 29872859, PMID 305471, PMID 30974433, PMID 31935746, PMID 32687801, PMID 33006765, PMID 33876883, PMID 34935127, PMID 36863329, PMID 38365446, PMID 41218846, PMID 42612036, PMID 10379020, PMID 10400143, PMID 10545589, PMID 10625862, PMID 10632246, PMID 10654946
U10HD021385 (18), U10HD027880 (18), U10HD027853 (17), U10HD021364 (16), U10HD027904 (16), U10HD027851 (15), U10HD027856 (15), U10HD034216 (15), U10HD021373 (14), U10HD027871 (14), M01RR008084 (12), U10HD021397 (11), M01RR000070 (10), M01RR000750 (10), U10HD021415 (10)