379 completed, 63 unknown, 46 recruiting, 24 terminated. 302 Not applicable, 78 Phase 2, 62 Phase 4, 59 Phase 3, 43 Phase 1.
Follow Glucose: new trials by email Literature Review of Glucose trials Research Report on Glucose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Galactose as a Substrate for Post-Exercise Skeletal Muscle Glycogen Repletion in Individuals With Type 1 Diabetes galactose - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Aarhus | 16 | 2027-02-01 | 2026-08-19 |
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Human Models of Selective Insulin Resistance: Pancreatic Clamp Insulin human, Octreotide Acetate, Glucagon - Insulin Resistance, Hyperinsulinemia | Phase 1 | Not yet recruiting | Columbia University | 36 | 2027-01-01 | 2026-02-06 |
| Dexmedetomidine for Invasive Ventilation In the NEOnate Dexmedetomidine Injectable Solution, Glucose 5% Injectable Solution - Invasive Ventilation, Infant Pain | Phase 2 / Phase 3 | Not yet recruiting | Centre Hospitalier Intercommunal Creteil | 246 | 2027-01-01 | 2026-08-26 |
| The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery Lidocaine HCl 0.8% in D5W, Dextrose 5% in water - Pain, Post Operative Analgesia | Phase 4 | Recruiting | Vanderbilt University Medical Center | 2290 | 2026-10-26 | 2026-11-02 |
| The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension Dextrose, Sildenafil 20mg - Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) | Phase 2 / Phase 3 | Recruiting | Silvia Ulrich | 20 | 2026-10-26 | 2026-11-04 |
| Rapid Rehydration for Severe Hypernatremia Intravenous Dextrose 5% solution - Hypernatremia | Phase 2 | Recruiting | Columbia University | 80 | 2026-10-22 | 2026-10-27 |
| Postprandial Glycemic and GLP-1 Responses to Modified Full-sugar Drinks Sucrose Beverage, Glucose + Fructose beverage, Sucrose with EGCG Beverage - Postprandial Glucose, GLP-1 Concentration | Not applicable | Active not recruiting | Purdue University | 16 | 2026-10-21 | 2026-11-05 |
| The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients Dextrose 50% Intravenous Solution, Lidocaine 1% Injectable Solution - Ehlers-Danlos Syndrome, Low Back Pain | Phase 3 | Withdrawn | Tulane University | 2026-10-05 | 2026-10-08 | |
| Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer Trilaciclib, Saline (0.9% NaCl) - Limited Stage Small Cell Lung Cancer | Phase 3 | Recruiting | Pharmacosmos A/S | 120 | 2026-09-01 | 2026-10-02 |
| Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome Perineural injection with 5% dextrose (D5W)., Local ozone injection, Local glucocorticoid injection (dexamethasone). - Carpal Tunnel Syndrome (CTS), Glucocorticoid | Not applicable | Not yet recruiting | Tanta University | 105 | 2026-07-30 | 2026-03-27 |
| Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance Metyrapone And Hydrocortisone, Dextrose, insulin - Shift Work Schedule, Circadian Rhythm | Phase 4 | Recruiting | Washington State University | 48 | 2026-07-16 | 2026-09-18 |
| Lactate and Glycerol Contribution to Gluconeogenesis Glycerol, Lactate, Glucose - Type 2 Diabetes, Obesity | Not applicable | Not yet recruiting | Rutgers, The State University of New Jersey | 48 | 2026-07-01 | 2025-12-02 |
| Betamethasone vs Dextrose Injections in Trigger Finger Betamethasone, Dextrose Injection - Trigger Finger | Not applicable | Recruiting | Istanbul University - Cerrahpasa | 42 | 2026-06-30 | 2026-07-28 |
| The Effect of Breast Milk, 10% and 20% Dextrose on Pain and Physiological Variables During Heel Puncture in Infants Administering oral breast milk in a supportive position, Administering oral 10% dextrose in a supportive position, Administering oral 20% dextrose in a supportive position - Newborn Care, Pain Management | Not applicable | Recruiting | Mersin University | 96 | 2026-06-18 | 2026-10-27 |
| Exogenous Carbohydrate Oxidation During High Intensity Exercise glucose - Exercise Metabolism | Not applicable | Active not recruiting | University of Bath | 6 | 2026-06-08 | 2026-07-08 |
| Effectiveness of Dextrose Pleurodesis for the Management of Post-Operative Air Leak 50% Dextrose Pleurodesis, Standard of Care Chest Drainage - Post Operative Pulmonary Air Leak | Phase 2 | Not yet recruiting | Thomas Jefferson University | 80 | 2026-06-01 | 2026-04-23 |
| Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus Muscle Biopsy, Jell-O with Amino acids, Dextrose - Type 1 Diabetes | Not applicable | Withdrawn | Mayo Clinic | 2026-06-01 | 2026-08-05 | |
| Enhanced Recovery After Surgery in Hysterectomy Patients dextrose (5%), ERAS protocols - Enhanced Recovery After Surgery (ERAS) Protocol | Not applicable | Not yet recruiting | Cairo University | 78 | 2026-06-01 | 2026-05-04 |
| Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD Dextrose 5% in water bilateral injection, Normal saline bilateral injection - PTSD | Phase 4 | Recruiting | Dr. Dean Reeves Clinic | 50 | 2026-05-16 | 2026-09-16 |
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Obesity (40) · Insulin Resistance (29) · Diabetes Mellitus (26) · Pain (21) · Diabetes Mellitus, Type 2 (18) · Diabetes Mellitus, Type 1 (17) · Carpal Tunnel Syndrome (16) · Hyperglycemia (15) · Hypoglycemia (13) · Appetitive Behavior (12) · Overweight (12) · Osteoarthritis, Knee (10) · Premature Birth (10) · Sepsis (9) · Non-alcoholic Fatty Liver Disease (8)
Agricultural University of Athens (14) · University Hospital, Basel, Switzerland (13) · Merck Sharp & Dohme LLC (9) · University of Toronto (9) · University of Sao Paulo (8) · Mayo Clinic (7) · Columbia University (6) · Ankara City Hospital Bilkent (5) · McGill University Health Centre/Research Institute of the McGill University Health Centre (5) · Tranzyme, Inc. (5) · University Health Network, Toronto (5) · University of Chicago (5) · Assiut University (4) · Bristol-Myers Squibb (4) · Cairo University (4)
United States (164) · Canada (55) · Turkey (Türkiye) (34) · United Kingdom (32) · Denmark (24) · China (23) · France (21) · Switzerland (21) · Brazil (20) · Greece (19) · Taiwan (19) · Italy (18) · Egypt (16) · Germany (16) · Netherlands (16)
Emilia Papakonstantinou, PhD (8) · Bruno Gualano, PhD (5) · Christoph Beglinger, MD (5) · Aimilia Papakonstantinou, PhD (4) · Joshua R Cook, MD, PhD (4) · Thomas MS Wolever, MD, PhD (4) · Adrian Vella, MD (3) · Christoph Beglinger, Prof (3) · Christoph Beglinger, Prof. (3) · Francesca Scazzina, PhD (3) · Furio Brighenti, PhD (3) · Yung-Tsan Wu, MD (3) · Agussalim Bukhari, MD, Ph.D (2)
PMID 21623291, PMID 15138901, PMID 15321413, PMID 15920223, PMID 16443140, PMID 18173431, PMID 19092350, PMID 19447599, PMID 19672175, PMID 20011857, PMID 20455872, PMID 21307769, PMID 21334503, PMID 21334504, PMID 22108086, PMID 22326199, PMID 22813360, PMID 23135692, PMID 23262963, PMID 23739196, PMID 23969793, PMID 23997449, PMID 24034832, PMID 24946047, PMID 25146109, PMID 25201313, PMID 25821536, PMID 25936783, PMID 26692415, PMID 26694495, PMID 27574464, PMID 27629425, PMID 27870737, PMID 29806553, PMID 30187524, PMID 34669959, PMID 8267196, PMID 11145118, PMID 11162047, PMID 11172481, PMID 11238483, PMID 11512567, PMID 11527163, PMID 11743518, PMID 12145777, PMID 12399273, PMID 12450897, PMID 12540646, PMID 12563043, PMID 12630816
2015 (5), 2023 (3), P30DK063608 (3), 2014 (2), 2018 (2), K12DK133995 (2), U10HD036790 (2), UL1TR001082 (2), 1UM1HL116885-01 (1), 2016 (1), 2017 (1), 2025 (1), K01DK120562 (1), K07MH001197 (1), K23AT001879 (1)