24 completed, 6 terminated, 6 unknown, 5 recruiting. 44 Phase 2, 7 Phase 3, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 44 | Completed 24, Terminated 6, Unknown 6, Recruiting 5, Withdrawn 2, Not yet recruiting 1 |
| Phase 3 | 7 | Completed 4, Unknown 2, Withdrawn 1 |
| Phase 1 | 4 | Completed 4 |
Follow Post-Traumatic Stress Disorder: new trials by email Literature Review of Post-Traumatic Stress Disorder trials Research Report on Post-Traumatic Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders MDMA - Post-Traumatic Stress Disorder, Adjustment Disorders | Phase 2 | Not yet recruiting | Nautilus Sanctuary | 30 | 2026-10-01 | 2026-05-05 |
| Long-Term Outcomes Following HBOT Hyperbaric Oxygen Therapy (HBOT) - Traumatic Brain Injury, Post-Concussive Symptoms | Phase 2 | Recruiting | Summit Hyperbarics and Wellness | 35 | 2026-06-18 | 2026-07-28 |
| BXCL501 After Stress to Increase Recovery Success BXCL501 (dexmedetomidine HCl), Placebo - Acute Stress Reaction, Acute Stress Disorder | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 100 | 2026-02-23 | 2026-04-14 |
| Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder Propofol - PTSD, Post-traumatic Stress Disorder | Phase 2 | Recruiting | Stanford University | 42 | 2025-07-21 | 2026-10-02 |
| Personalized Brain Stimulation to Treat Chronic Concussive Symptoms Active cTBS, Inactive/Sham cTBS, Imaginal exposure - Post-Concussion Syndrome, Concussion, Brain | Phase 2 | Recruiting | University of California, Los Angeles | 75 | 2024-03-06 | 2026-02-24 |
| Pimavanserin for Insomnia in Veterans With PTSD pimavanserin, Placebo - Post-traumatic Stress Disorder, Insomnia | Phase 2 | Recruiting | VA Office of Research and Development | 60 | 2023-12-28 | 2026-05-04 |
| Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD APEX-002-A02, Placebo - Post-traumatic Stress Disorder, Depression | Phase 2 | Unknown | Apex Labs Ltd. | 160 | 2023-12-15 | 2023-11-29 |
| MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder Prolonged exposure therapy, MDMA, Niacin - PTSD, Alcohol Use Disorder | Phase 2 | Unknown | University of Sydney | 120 | 2023-09-19 | 2023-11-07 |
| A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder 60 mg PRAX-114 or 40 mg PRAX-114, Placebo, 40 mg PRAX-114 - Post-traumatic Stress Disorder, Post Traumatic Stress Disorder | Phase 2 | Terminated | Praxis Precision Medicines | 11 | 2022-01-25 | 2022-12-01 |
| A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder BI 1358894, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Boehringer Ingelheim | 318 | 2021-12-07 | 2024-11-07 |
| Combined Ketamine and eCBT Intervention for PTSD Ketamine, Online Trauma-Focused Cognitive Behavioural Therapy - Post-Traumatic Stress Disorder | Phase 2 | Unknown | Queen's University | 16 | 2021-08-01 | 2022-08-11 |
| A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD) BNC210, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Bionomics Limited | 212 | 2021-07-27 | 2025-02-06 |
| Study of the Safety and Efficacy of Nabiximols Oromucosal Spray Versus Placebo in Patients With Post-traumatic Stress Disorder Nabiximols, Placebo - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Withdrawn | Jazz Pharmaceuticals | 2021-02-01 | 2022-06-03 | |
| Ketamine and Prolonged Exposure in PTSD ketamine-enhanced prolonged exposure - Post-traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Minneapolis Veterans Affairs Medical Center | 12 | 2019-04-03 | 2026-10-14 |
| Pilot rTMS for AUD+mTBI repetitive transcranial magnetic stimulation - Alcohol Use Disorder, Mild Traumatic Brain Injury | Phase 2 | Terminated | VA Office of Research and Development | 2 | 2019-03-21 | 2026-10-30 |
| Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder Placebo oral capsule, NYX-783 - Post-Traumatic Stress Disorder | Phase 2 | Completed | Aptinyx | 160 | 2019-01-25 | 2022-05-17 |
| Phase II Study of BNC210 in PTSD BNC210, Placebo - Post-Traumatic Stress Disorder | Phase 2 | Completed | Bionomics Limited | 193 | 2016-06-30 | 2023-02-27 |
| Effectiveness of PTSD Treatment For Suicidal and Multi-Diagnostic Clients Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol - Post-traumatic Stress Disorder, Suicide | Phase 2 / Phase 3 | Completed | University of Washington | 35 | 2016-02-01 | 2019-09-17 |
| The Role of Computerized Training in Post-Traumatic Stress Disorder Cognitive Bias Modification of Appraisals (CBM-App), Peripheral Vision Task (control condition) - Post-Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Ruhr University of Bochum | 80 | 2016-02-01 | 2019-09-17 |
| Trauma Management Therapy for OEF and OIF Combat Veterans 17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy - Post-Traumatic Stress Disorder, Combat Disorders | Phase 2 | Completed | University of Central Florida | 180 | 2015-11-01 | 2017-10-31 |
Showing 20 of 44. Sign in to see all of them.
Stress Disorders, Post-Traumatic (44) · Anxiety Disorders (6) · Depression (4) · Wounds and Injuries (4) · Alcoholism (3) · Brain Concussion (3) · Combat Disorders (3) · Depressive Disorder, Major (3) · Post-Concussion Syndrome (3) · Brain Injuries, Traumatic (2) · Psychological Well-Being (2) · Stress Disorders, Traumatic, Acute (2) · Adjustment Disorders (1) · Aggression (1) · Autonomic Nervous System Diseases (1)
Mental Disorders (43) · Stress Disorders, Traumatic (43) · Trauma and Stressor Related Disorders (43) · Behavior (9) · Behavioral Symptoms (6) · Nervous System Diseases (6) · Chemically-Induced Disorders (5) · Brain Diseases (4) · Brain Injuries (4) · Central Nervous System Diseases (4) · Head Injuries, Closed (4) · Substance-Related Disorders (4) · Trauma, Nervous System (4) · Wounds and Injuries (4) · Wounds, Nonpenetrating (4)
Cognitive Behavioral Therapy (2) · Implosive Therapy (2) · N-Methyl-3,4-methylenedioxyamphetamine (2) · Propranolol (2) · Sertraline (2) · Virtual Reality Exposure Therapy (2) · Atorvastatin (1) · Carvedilol (1) · Control Groups (1) · Cycloserine (1) · Dexmedetomidine (1) · Dialectical Behavior Therapy (1) · Exercise (1) · Hyperbaric Oxygenation (1) · Ketamine (1)
VA Office of Research and Development (3) · Bionomics Limited (2) · Duke University (2) · GlaxoSmithKline (2) · University Hospital, Toulouse (2) · University of Konstanz (2) · University of Pennsylvania (2) · Apex Labs Ltd. (1) · Aptinyx (1) · Baylor College of Medicine (1) · Boehringer Ingelheim (1) · Columbia Northwest Pharmaceuticals (1) · Emory University (1) · INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium (1) · Jazz Pharmaceuticals (1)
United States (32) · Canada (3) · Australia (2) · France (2) · Germany (2) · Burundi (1) · Croatia (1) · Finland (1) · Israel (1) · Japan (1) · Mexico (1) · Poland (1) · Republic of the Congo (1) · Sweden (1) · United Kingdom (1)
Jonathan Davidson, M.D. (2) · Amy A Herrold, PhD BA (1) · Anselm Crombach, Dipl.-Psych. (1) · Arifulla Khan, MD (1) · Barbara O Rothbaum, PhD/ABPP (1) · Barbara Rothbaum, Ph.D. (1) · Boris D Heifets, MD, PhD (1) · Brenda Wiederhold, PhD (1) · Candice M. Monson, PhD (1) · Casey Paleos, M.D. (1) · Claudia S Robertson, MD (1) · Cynthia Price, PhD (1) · Deborah C Beidel, Ph.D., ABPP (1) · Edna B Foa, Ph.D. (1)
PMID 22893167, PMID 23738530, PMID 25809565, PMID 26654474, PMID 28006970, PMID 29961004, PMID 33165153, PMID 33176074, PMID 33612830, PMID 34092549, PMID 35189456, PMID 38872596, PMID 39647171, PMID 40261001, PMID 42409408
IK2CX002363-01A1 (1), IK2RX000949 (1), R01DA023507 (1), R01MH062003 (1), R34MH076813 (1), R34MH095210 (1), R34MH106598 (1)