197 completed, 31 unknown, 30 recruiting, 18 active not recruiting. 204 Not applicable, 40 Phase 2, 17 Phase 4, 10 Phase 3, 8 Phase 1.
Follow this condition Literature Review of Aggression trials Research Report on Aggression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation Regulating Together group therapy - Autism, Intellectual Disabilities With Other Behavioral Symptoms | Not applicable | Recruiting | Children's Mercy Hospital Kansas City | 10 | 2027-10-01 | 2026-09-03 |
| Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation Regulating Together group therapy - Prader-Willi Syndrome | Not applicable | Recruiting | Children's Mercy Hospital Kansas City | 10 | 2027-01-01 | 2026-09-02 |
| Manualized Assessment and Treatment Model of Challenging Behavior Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking - Problem Behavior, Aggression | Not applicable | Recruiting | Rutgers, The State University of New Jersey | 30 | 2026-12-31 | 2026-05-08 |
| Effect of Verbal De-Escalation-Based Simulation on Agitation Management, Perception of Aggression, and Impact of Aggression in Emergency Department Nurses Standard Verbal De-Escalation Training, Verbal De-Escalation-Based Simulation Training - Agitation Management, Aggression | Not applicable | Not yet recruiting | Uskudar University | 78 | 2026-10-01 | 2026-08-25 |
| Intensive Care Unit Conflict Mediation Study SEM DESTINO - Aggression, Critical Care Staff | Not applicable | Not yet recruiting | Hospital Israelita Albert Einstein | 100 | 2026-10-01 | 2026-06-02 |
| Just-in-Time Coping Prompts for Reactive Digital Behavior in College Students Momentary coping prompt, Active control message - Emotional Regulation, Alcohol Drinking in College | Not applicable | Recruiting | University of Florida | 80 | 2026-09-21 | 2026-10-21 |
| Momentary Coping Prompts and Hair Steroids in College Students Momentary coping prompt, Active control message - Emotional Regulation, Alcohol Drinking in College | Not applicable | Recruiting | University of Florida | 80 | 2026-09-21 | 2026-10-21 |
| Methodology of Super-Early Training of Developer Engineers and Leading Analysts With a Diagnosis of ADHD/ASD for Ensuring the Engineering Sovereignty of the State: Time Horizon: 2026-2038-2050 Voice of Sleep "MamaBee" training modules (Fairy Tales) - Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Active not recruiting | Pisareva Citadel Group LLC | 2 | 2026-08-01 | 2026-09-28 |
| BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis BRAVE (Behavioral Response Against Violence Engagement), Treatment As Usual (TAU) - Violence Risk, Early Psychosis | Not applicable | Recruiting | Howard University | 30 | 2026-07-02 | 2026-07-29 |
| A Virtual Reality Mindfulness Application for Aggression in Schizophrenia Mindfulness-Based Virtual Reality Intervention - Schizophrenia Disorder, Schizoaffecitve Disorder | Not applicable | Recruiting | Manhattan Psychiatric Center | 58 | 2026-06-05 | 2026-06-10 |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-05-18 | 2026-05-18 |
| Death, Dying, Violence and Aggression as Shown on Medical Television Series. End of Life Care, Violent Aggressive Behavior | Not yet recruiting | King's College Hospital NHS Trust | 500 | 2026-05-10 | 2026-02-18 | |
| Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico Cool roof - Resting Heart Rate, Blood Glucose Control | Not applicable | Not yet recruiting | Aditi Bunker | 800 | 2026-04-01 | 2026-03-12 |
| Using an Innovative Implementation Strategy to Increase the Translation of Effective Youth Violence Prevention Programs in Schools iCHAMPS-YVP - Bullying, Teen Dating Violence | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 25 | 2026-04-01 | 2025-11-03 |
| Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression Creative Drama Program, Film Viewing Sessions - Gender Role, Aggression | Not applicable | Not yet recruiting | Ataturk University | 75 | 2026-03-30 | 2026-04-09 |
| Flourish in Schools Pilot Study Flourish - Psychological Distress, Suicidal Ideation | Not applicable | Recruiting | Candice Biernesser | 20 | 2026-03-14 | 2026-04-01 |
| Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants CNS Stimulant, Placebo, CNS Stimulant open label first phase - ADHD - Attention Deficit Disorder With Hyperactivity, Irritability | Phase 4 | Recruiting | Milton S. Hershey Medical Center | 136 | 2026-03-05 | 2026-04-20 |
| Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome SRX246, Placebo - Aggressive Behavior in Fragile X Syndome | Phase 2 | Not yet recruiting | Azevan Pharmaceuticals | 80 | 2026-03-01 | 2026-01-09 |
| Chatbot to Support Healthcare Professionals Experiencing Workplace Aggression Chatbot SANIDAD SEGURA - Workplace Violence, Health Professionals | Completed | Distrito Sanitario Almeria | 105 | 2026-02-19 | 2026-06-03 | |
| Inflammatory Challenge in Human Aggression. Endotoxin (E. coli O:113, Reference Endotoxin), Saline (Placebo) - Intermittent Explosive Disorder | Phase 2 | Recruiting | Ohio State University | 112 | 2026-02-16 | 2026-03-27 |
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Bullying (48) · Depression (31) · Cyberbullying (24) · Psychomotor Agitation (20) · Stress Disorders, Post-Traumatic (20) · Anxiety Disorders (17) · Alzheimer Disease (16) · Autistic Disorder (15) · Problem Behavior (15) · Self-Injurious Behavior (15) · Psychological Well-Being (14) · Psychotic Disorders (14) · Attention Deficit Disorder with Hyperactivity (13) · Antisocial Personality Disorder (12)
Social Behavior (303) · Behavioral Symptoms (298) · Behavior (294) · Aberrant Motor Behavior in Dementia (237) · Mental Disorders (139) · Harassment, Non-Sexual (66) · Pathological Conditions, Signs and Symptoms (56) · Nervous System Diseases (49) · Neurodevelopmental Disorders (44) · Signs and Symptoms (44) · Neurologic Manifestations (37) · Brain Diseases (30) · Central Nervous System Diseases (30) · Neurobehavioral Manifestations (27)
Risperidone (8) · Therapeutics (7) · Aripiprazole (5) · Cognitive Behavioral Therapy (5) · Haloperidol (5) · Transcranial Direct Current Stimulation (5) · Docosahexaenoic Acids (3) · Early Intervention, Educational (3) · Ethanol (3) · Guanfacine (3) · Midazolam (3) · Olanzapine (3) · Palliative Care (3) · Valproic Acid (3) · Amantadine (2)
University of Konstanz (10) · Yale University (9) · VA Office of Research and Development (7) · Indiana University (5) · Rutgers, The State University of New Jersey (5) · University of Deusto (5) · Aditi Bunker (4) · Washington University School of Medicine (4) · Karolinska Institutet (3) · New York State Psychiatric Institute (3) · Ohio State University (3) · Rhode Island Hospital (3) · Selcuk University (3) · University of Florida (3) · University of Medicine and Dentistry of New Jersey (3)
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Esther Calvete, PhD (4) · Collin Tukuitonga, Sir. Dr. (3) · Adrian Raine, DPhil (2) · Alan S Lewis, MD, PhD (2) · Arnstein Mykletun, PhD (2) · Daniel Brandeis, PhD (2) · Denis Sukhodolsky, Ph.D. (2) · Denis Sukhodolsky, PhD (2) · Flora M Hammond, MD (2) · Mark E. Kunik, MD MPH (2) · Megan Ranney, MD MPH (2) · Olivia Choy, PhD (2) · Pia Enebrink, PhD (2) · Shannon R. Miles, PhD (2) · Sherie L. Novotny, MD (2)
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K23MH126312 (2), 1IK2RX001298-01A2 (1), 2008 (1), 2009 (1), 2019 (1), 2025 (1), I01CX002135 (1), K01AA027564 (1), K01MH131872 (1), K23MH116339 (1), KL2TR002367 (1), P01HL040962 (1), P50MH115838 (1), R01AA025090 (1), R01AG021488 (1)