13 completed, 2 terminated, 2 unknown, 1 active not recruiting. 19 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 13, Terminated 2, Unknown 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 7 | Completed 4, Unknown 2, Withdrawn 1 |
Follow Post-Traumatic Stress Disorder: new trials by email Literature Review of Post-Traumatic Stress Disorder trials Research Report on Post-Traumatic Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MDMA-assisted Massed Prolonged Exposure for PTSD 3,4 Methylenedioxymethamphetamine, Prolonged Exposure - Post-Traumatic Stress Disorder | Phase 3 | Active not recruiting | Healing Breakthrough | 20 | 2024-10-25 | 2026-08-26 |
| Study of the Safety and Efficacy of Nabiximols Oromucosal Spray Versus Placebo in Patients With Post-traumatic Stress Disorder Nabiximols, Placebo - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Withdrawn | Jazz Pharmaceuticals | 2021-02-01 | 2022-06-03 | |
| Using Reconsolidation Blockade to Treat Trauma Related Disorders After Paris Attacks: an Effectiveness Study β-adrenergic blocker propranolol, Treatment as usual - Post-traumatic Stress Disorder | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 364 | 2016-05-27 | 2023-03-22 |
| Helping Children With Trauma Trauma Systems Therapy (TST), Treatment as Usual (TAU) - Trauma, Post-Traumatic Stress Disorder | Phase 3 | Terminated | NYU Langone Health | 14 | 2016-02-01 | 2017-03-31 |
| Effectiveness of PTSD Treatment For Suicidal and Multi-Diagnostic Clients Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol - Post-traumatic Stress Disorder, Suicide | Phase 2 / Phase 3 | Completed | University of Washington | 35 | 2016-02-01 | 2019-09-17 |
| Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD) Placebo, Brexpiprazole - Post-traumatic Stress Disorder, PTSD | Phase 3 | Terminated | H. Lundbeck A/S | 417 | 2013-12-01 | 2017-03-13 |
| Intervention to Support the Reintegration of Former Combatants and Soldiers NET for Forensic Offender Rehabilitation (FORNET): a variant of Narrative Exposure Therapy, Control group - Appetitive Aggression, Post-traumatic Stress Disorder | Phase 2 / Phase 3 | Unknown | University of Konstanz | 100 | 2012-06-01 | 2013-07-30 |
| Maximizing Treatment Outcome and Examining Sleep in Post-traumatic Stress Disorder (PTSD) Prolonged Exposure, Exercise, Wellness Intervention - Post-Traumatic Stress Disorder | Phase 3 | Completed | Southern Methodist University | 9 | 2010-09-01 | 2014-12-10 |
| Maximizing Treatment Outcome in Post-Traumatic Stress Disorder (PTSD) Prolonged Exposure, Exercise - Post-Traumatic Stress Disorder | Phase 3 | Completed | University of Texas at Austin | 28 | 2010-09-01 | 2015-12-29 |
| Comparison of Videoconference and Face-to-Face Delivery of Cognitive Processing Therapy for Posttraumatic Stress Disorder Cognitive Processing Therapy (CPT) - Post-Traumatic Stress Disorder | Phase 3 | Completed | University of Wisconsin, Madison | 90 | 2009-12-01 | 2015-10-02 |
| Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder Cognitive behavioral couples therapy for post-traumatic stress disorder (CBCT for PTSD) - Post-traumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Toronto Metropolitan University | 80 | 2008-08-01 | 2013-11-26 |
| RCT of CBT Combined With D-Cycloserine for Treating PTSD D-cycloserine, Cognitive-Behavioral Therapy - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Unknown | Université de Montréal | 20 | 2007-02-01 | 2007-03-27 |
| Levetiracetam in Post-Traumatic Stress Disorder levetiracetam, Placebo, Levetriracetam - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Duke University | 16 | 2005-11-01 | 2014-07-21 |
| KIDNET Versus Meditation/Relaxation - a Dissemination RCTT for Children in Sri Lanka Traumatized by the War and the Tsunami KIDNET, Meditation-Relaxation - Post-Traumatic Stress Disorder | Phase 3 | Completed | University of Konstanz | 31 | 2005-01-01 | 2009-01-12 |
| Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder Quetiapine Fumarate, quetiapine fumarate placebo - Post-Traumatic Stress Disorder | Phase 3 | Completed | AstraZeneca | 90 | 2004-12-01 | 2010-12-09 |
| Comparison of Two Treatments for Post-Traumatic Stress Disorder Sertraline, Cognitive behavioral therapy (CBT) - Post-Traumatic Stress Disorder | Phase 3 | Completed | Case Western Reserve University | 200 | 2004-09-01 | 2022-05-24 |
| The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women Trauma Recovery and Empowerment Model (TREM), Usual care - Post-Traumatic Stress Disorder, Mental Disorders | Phase 3 | Completed | Dartmouth-Hitchcock Medical Center | 300 | 2004-04-01 | 2012-07-23 |
| Risperidone Augmentation for PTSD sertraline and risperidone - Post-Traumatic Stress Disorder | Phase 2 / Phase 3 | Completed | Duke University | 80 | 2004-04-01 | 2014-09-22 |
| BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder Paroxetine - Post-Traumatic Stress Disorder | Phase 3 | Completed | GlaxoSmithKline | 52 | 2002-05-01 | 2014-03-10 |
Stress Disorders, Post-Traumatic (19) · Anxiety Disorders (4) · Wounds and Injuries (3) · Motor Activity (2) · Depression (1) · Mental Disorders (1) · Self-Injurious Behavior (1) · Substance-Related Disorders (1) · Suicide (1)
Stress Disorders, Traumatic (19) · Trauma and Stressor Related Disorders (19) · Mental Disorders (18) · Behavior (4) · Behavioral Symptoms (2) · Chemically-Induced Disorders (1)
Cognitive Behavioral Therapy (2) · Exercise (2) · Sertraline (2) · Therapeutics (2) · 2-cyclohexylidenhydrazo-4-phenyl-thiazole (1) · Control Groups (1) · Cycloserine (1) · Dialectical Behavior Therapy (1) · Levetiracetam (1) · N-Methyl-3,4-methylenedioxyamphetamine (1) · Paroxetine (1) · Quetiapine Fumarate (1) · Risperidone (1) · brexpiprazole (1) · nabiximols (1)
Duke University (2) · University of Konstanz (2) · Assistance Publique - Hôpitaux de Paris (1) · AstraZeneca (1) · Case Western Reserve University (1) · Dartmouth-Hitchcock Medical Center (1) · GlaxoSmithKline (1) · H. Lundbeck A/S (1) · Healing Breakthrough (1) · Jazz Pharmaceuticals (1) · NYU Langone Health (1) · Southern Methodist University (1) · Toronto Metropolitan University (1) · University of Texas at Austin (1) · University of Washington (1)
United States (12) · Canada (2) · France (2) · Australia (1) · Estonia (1) · Finland (1) · Italy (1) · Martinique (1) · Poland (1) · Republic of the Congo (1) · Serbia (1) · South Africa (1) · Sweden (1)
Jonathan Davidson, M.D. (2) · Barbara Rothbaum, Ph.D. (1) · Candice M. Monson, PhD (1) · Glenn Saxe, MD (1) · Gregory J. McHugo, PhD (1) · Leslie Morland, Psy.D. (1) · Lori A. Zoellner, PhD (1) · Melanie S Harned, PhD (1) · Norah C. Feeny, PhD (1) · Thomas Elbert, Prof. Dr. (1)
PMID 25706090, PMID 19439099, PMID 22893167, PMID 23587015, PMID 24717377, PMID 26397721, PMID 29541927, PMID 30336702, PMID 31703570, PMID 32662191, PMID 34672659, PMID 35404227, PMID 39509231
2016 (1), R01MH066348 (1), R01MH068252 (1), R34MH076813 (1), R34MH106598 (1)