47 completed, 12 recruiting, 7 unknown, 2 terminated. 61 Not applicable, 6 Phase 2, 5 Phase 1, 2 Phase 3.
Follow Implosive Therapy: new trials by email Literature Review of Implosive Therapy trials Research Report on Implosive Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TMS + Exposure Therapy for Pediatric OCD: Second Phase Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area, Transcranial Magnetic Stimulation: Sham, Exposure with Response Prevention - Obsessive Compulsive Behavior | Not applicable | Recruiting | Bradley Hospital | 60 | 2026-10-31 | 2026-10-19 |
| Use of Augmented Reality and Virtual Reality During Cognitive Behavioral Therapy for Needle Phobia Mixed reality (XR) Exposure Therapy - Needle Phobia, Virtual Reality | Not applicable | Enrolling by invitation | Stanford University | 20 | 2026-09-01 | 2026-08-18 |
| Adapting Exposure for Adolescent AN Exposure Therapy for Anorexia (Exp-AN) - Anorexia Nervosa | Not applicable | Recruiting | Milton S. Hershey Medical Center | 16 | 2026-02-20 | 2026-10-20 |
| Multifaceted Intervention to Restore Resilience and Overcome Risk webSTAIR, ExpoTx, PsychoEd - Military Sexual Trauma, Intimate Partner Violence | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 136 | 2025-09-12 | 2026-09-21 |
| Brief Exposure and Exercise for PTSD. Brief exposure therapy and exercise - PTSD - Post Traumatic Stress Disorder | Not applicable | Completed | Troy Hubert | 12 | 2025-06-25 | 2026-04-08 |
| Internet-Delivered Psychological Treatments for Chronic Pain in Adolescents: ACT and Pain Education. Acceptance and Commitment Therapy, Pain Science Education - Chronic Pain, Nociplastic Pain | Not applicable | Recruiting | Region Stockholm | 150 | 2025-05-01 | 2025-05-20 |
| Study of the Effectiveness of VRET Combined With tDCS in the Treatment of PTSD in Ukrainian Veterans and Civilians Virtual reality exposure therapy, transcranial direct current stimulation, Imaginal exposure therapy - PTSD - Post Traumatic Stress Disorder | Not applicable | Recruiting | Malek Bajbouj | 100 | 2025-04-22 | 2026-08-11 |
| Exposure Therapy for Late-life Anxiety Exposure therapy, Usual Care - Anxiety Disorders, Anxiety Depression | Not applicable | Recruiting | ProPersona | 170 | 2025-02-12 | 2025-05-29 |
| Mechanisms of Exposure Therapy for OCD Exposure therapy - Obsessive-Compulsive Disorder | Not applicable | Recruiting | Mclean Hospital | 400 | 2024-10-16 | 2026-06-25 |
| Reward Processing and Exposure Therapy for Social Anxiety Disorder Positive Affect Treatment - Behavioral (PAT-B), Relaxation Treatment, Exposure Therapy - Social Anxiety Disorder (Social Phobia), Public Speaking Anxiety | Not applicable | Recruiting | University of California, Los Angeles | 94 | 2024-09-26 | 2026-04-02 |
| Exposure Therapy Study In Adults With Eating Disorders Exposure Therapy - Eating Disorders, Anorexia Nervosa | Not applicable | Completed | Milton S. Hershey Medical Center | 25 | 2024-05-02 | 2026-09-29 |
| Brief-intensive CBT Versus Once-weekly CBT in Anxiety-related Disorders Cognitive behavioral therapy (CBT) - Anxiety Disorders, Obsessive-Compulsive Disorder | Not applicable | Active not recruiting | Amsterdam UMC, location VUmc | 120 | 2024-04-26 | 2026-05-29 |
| Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial exposure therapy in virtual reality, Wait list - Obsessive-compulsive Disorder | Not applicable | Recruiting | National Institute of Mental Health, Czech Republic | 30 | 2024-03-20 | 2025-10-03 |
| TMS + Exposure Therapy for Pediatric OCD Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham - Obsessive-Compulsive Disorder | Not applicable | Completed | Bradley Hospital | 59 | 2024-03-20 | 2026-10-19 |
| Personalized Brain Stimulation to Treat Chronic Concussive Symptoms Active cTBS, Inactive/Sham cTBS, Imaginal exposure - Post-Concussion Syndrome, Concussion, Brain | Phase 2 | Recruiting | University of California, Los Angeles | 75 | 2024-03-06 | 2026-02-24 |
| TMS for Exposure Therapy Resistant OCD repetitive transcranial magnetic stimulation (rTMS) - 1 Hz Real rTMS to the Pre-SMA, 1 Hz Sham rTMS to the Pre-SMA | Phase 3 | Recruiting | Amsterdam UMC, location VUmc | 250 | 2022-05-16 | 2026-03-04 |
| Neural Mechanisms of Imaginal and in Vivo Exposure Imaginal exposure, Exposure, Approach-avoidance conflict - Fear of Spiders | Not applicable | Completed | Uppsala University | 87 | 2022-04-07 | 2024-08-26 |
| EFFects of EXPosure and Cognitive-behavioural Therapy for Chronic BACK Pain Exposure therapy, Cognitive behavioral therapy - Chronic Low Back Pain | Not applicable | Completed | University of Kaiserslautern-Landau | 392 | 2022-03-01 | 2026-08-12 |
| Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth - Alcohol; Use, Problem, Posttraumatic Stress Disorder | Not applicable | Completed | University of Washington | 82 | 2021-06-02 | 2026-05-29 |
| Prevention of ICU-Related Anxiety in Lung Transplantation by Virtual Reality Therapy - PIRAT Study Exposure therapy with Virtual Reality. - Transplantation, Lung, Depression, Anxiety | Not applicable | Completed | Assistance Publique Hopitaux De Marseille | 62 | 2021-02-08 | 2025-10-01 |
Showing 20 of 72. Sign in to see all of them.
Stress Disorders, Post-Traumatic (21) · Anxiety Disorders (11) · Phobia, Social (8) · Phobia, Specific (8) · Obsessive-Compulsive Disorder (7) · Anorexia Nervosa (6) · Combat Disorders (6) · Phobic Disorders (6) · Agoraphobia (3) · Feeding and Eating Disorders (3) · Generalized Anxiety Disorder (3) · Panic Disorder (3) · Acrophobia (2) · Arachnophobia (2) · Autistic Disorder (2)
Bradley Hospital (4) · University of Texas at Austin (4) · Uppsala University (3) · VA Office of Research and Development (3) · Amsterdam UMC, location VUmc (2) · Emory University (2) · Milton S. Hershey Medical Center (2) · New York State Psychiatric Institute (2) · US Department of Veterans Affairs (2) · University of California, Los Angeles (2) · University of Central Florida (2) · University of Louisville (2) · University of North Carolina, Chapel Hill (2) · Weill Medical College of Cornell University (2) · Assistance Publique Hopitaux De Marseille (1)
United States (45) · Germany (6) · Netherlands (5) · Sweden (5) · Switzerland (2) · Canada (1) · Czechia (1) · Denmark (1) · France (1) · Norway (1) · Spain (1) · Turkey (Türkiye) (1)
Kristen Benito, PhD (3) · Catherine R Ayers, PhD (2) · Michael J Telch, PhD (2) · Aaron Lulla, MD, PhD (1) · Adam R. Cobb, MA (1) · Asle Hoffart, PhD (1) · Barbara O Rothbaum, PhD (1) · Barbara O Rothbaum, PhD, ABPP (1) · Brett T. Litz, PhD (1) · Brooks King-Casas, PhD (1) · Christine Conelea (1) · Christine Conelea, PhD (1) · Daneil W McNeil, PhD (1) · David Rosenbaum, Dipl.-Psych. (1)
PMID 14629992, PMID 16551156, PMID 20570701, PMID 22694905, PMID 23059145, PMID 25526831, PMID 28541646, PMID 30312595, PMID 30541492, PMID 30978622, PMID 31246050, PMID 32000725, PMID 32216149, PMID 32794449, PMID 33096291, PMID 33308073, PMID 33336858, PMID 33472513, PMID 34284836, PMID 34630934, PMID 34693989, PMID 37730963, PMID 37795783, PMID 38009966, PMID 38348490, PMID 38468293, PMID 39696590, PMID 42658588, PMID 42715141
2018 (1), F31MH100760 (1), F32AA029865 (1), K23MH133971 (1), R01AA027499 (1), R01MH082736 (1), R33MH133666 (1), R34HD065274 (1)