918 completed, 177 unknown, 147 recruiting, 51 not yet recruiting. 1105 Not applicable, 130 Phase 2, 72 Phase 3, 59 Phase 1, 54 Phase 4.
Follow Cognitive Behavioral Therapy: new trials by email Literature Review of Cognitive Behavioral Therapy trials Research Report on Cognitive Behavioral Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RISE for PTSD and Substance Use Disorder in Veterans Written Exposure Therapy, Cognitive Behavioral Therapy for Substance Use Disorders (skill components), Cognitive Behavioral Therapy for Substance Use Disorders - Stress Disorders, Post-Traumatic, Substance-Related Disorders | Not applicable | Not yet recruiting | VA Office of Research and Development | 30 | 2028-08-01 | 2026-10-29 |
| Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion - Tobacco Use Disorder | Not applicable | Not yet recruiting | VA Office of Research and Development | 120 | 2027-03-01 | 2026-07-20 |
| Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health. Gardasil 9 vaccine, Hepatitis B Virus Vaccine(HBV), Cognitive Behavioral Therapy - Hepatitis B, Human Papilloma Virus | Phase 4 | Not yet recruiting | Eunice Dube | 2140 | 2027-01-30 | 2026-07-30 |
| Intervention for Chronic Insufficient Sleep in Young Adult Cancer Patients and Survivors Cognitive behavioral therapy for insomnia, Sleep education and skills - Cancer | Not applicable | Not yet recruiting | Medstar Health Research Institute | 74 | 2027-01-04 | 2026-09-22 |
| Digitally Enhanced Cognitive-Behavioral Therapy Cognitive-behavioral therapy (CBT), Digital app - Depression in Adolescence, Obesity & Overweight | Not applicable | Not yet recruiting | Colorado State University | 60 | 2027-01-01 | 2026-09-03 |
| Neurobiology of Pain in Burn Survivors Cognitive Behavioral Therapy, Pain Education - Burn, Chronic Pain | Not applicable | Not yet recruiting | Spaulding Rehabilitation Hospital | 92 | 2027-01-01 | 2026-09-22 |
| Comparative Effects of Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, and Treatment-as-Usual on Depression Among People With Marital Crisis Acceptance and Commitment Therapy, Cognitive Behavioral Therapy - Depression - Major Depressive Disorder, Anxiety | Not applicable | Not yet recruiting | Universiti Sains Malaysia | 120 | 2027-01-01 | 2026-09-08 |
| Psychotherapy in Patients With Endometriosis: Cognitive Behavioral Therapy Versus Acceptance and Commitment Therapy Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT) - Endometriosis, Adenomyosis | Not applicable | Not yet recruiting | Fiammetta Cosci | 128 | 2027-01-01 | 2026-11-04 |
| Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU) - Autism Spectrum Disorder, Depressive Disorder | Not applicable | Not yet recruiting | Children's Hospital Los Angeles | 140 | 2026-12-01 | 2026-08-10 |
| Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study Cognitive Behavioral Therapy (CBT), Whole-Body Hyperthermia - Major Depressive Disorder | Not applicable | Not yet recruiting | University of California, San Francisco | 60 | 2026-12-01 | 2026-10-13 |
| Investigation of the Gut-Brain Axis in Alcohol Use Disorder Fecal Microbiota Transplantation (FMT) Procedure and Cognitive Behavioral Therapy (CBT) Procedure - Alcohol Use Disorder (AUD), Alcohol Abstinence | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 78 | 2026-11-16 | 2026-10-29 |
| Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL) Cognitive-behavioral therapy - Chronic Postsurgical Pain, Chronic Post-surgical Pain | Not applicable | Not yet recruiting | University Rovira i Virgili | 125 | 2026-11-01 | 2026-10-13 |
| Brief Psychoanalytic Therapy Versus Cognitive Behavioral Therapy for Major Depressive Disorder Brief Psychoanalytic Therapy, Cognitive Behavioral Therapy - Major Depressive Disorder (MDD | Not applicable | Not yet recruiting | Istanbul Nisantasi University | 90 | 2026-11-01 | 2026-10-05 |
| Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI) Cognitive Behavioral Therapy for Insomnia - Insomnia, Depression - Major Depressive Disorder | Not applicable | Not yet recruiting | Madigan Army Medical Center | 144 | 2026-11-01 | 2026-10-22 |
| Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online) Cognitive-Behavioral Therapy for Adolescent Binge Eating, Lifestyle Behavioral Obesity Intervention, Active Control - Binge Eating, Overweight and Obesity | Not applicable | Not yet recruiting | Indiana University | 159 | 2026-11-01 | 2026-10-29 |
| Cognitive-behavioral Therapy vs. Nutrition Counseling for Avoidant/Restrictive Food Intake Disorder Part II Cognitive-Behavioral Therapy for Avoidance Restrictive Food Intake Disorder (CBT-AR), Nutrition Counseling for Avoidant/Restrictive Food Intake Disorder - Avoidant/Restrictive Food Intake Disorder (ARFID) | Not applicable | Recruiting | Massachusetts General Hospital | 70 | 2026-11-01 | 2026-11-10 |
| TMS + Exposure Therapy for Pediatric OCD: Second Phase Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area, Transcranial Magnetic Stimulation: Sham, Exposure with Response Prevention - Obsessive Compulsive Behavior | Not applicable | Recruiting | Bradley Hospital | 60 | 2026-10-31 | 2026-10-19 |
| Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy - Obesity, Smoking Cessation | Phase 1 | Not yet recruiting | Medical University of South Carolina | 20 | 2026-10-01 | 2026-09-09 |
| Behavioral Resources and Awareness for Veterans With Episodic Migraine: Impact on Neurological Disability and Quality of Life- Pilot Cognitive behavioral therapy for migraine (CBTm), MEintervention - Migraine, Migraine Headache | Not applicable | Not yet recruiting | Yale University | 24 | 2026-10-01 | 2026-08-31 |
| Examining a New Insomnia Treatment for People Living With Secondary Breast Cancer. Sleep hygiene education, Cognitive behavioural therapy for insomnia (CBTi) - Insomnia, Breast Cancer Metastatic Breast Cancer | Not applicable | Not yet recruiting | University of Strathclyde | 50 | 2026-09-24 | 2026-10-05 |
Showing 20 of 1410. Sign in to see all of them.
Depression (238) · Sleep Initiation and Maintenance Disorders (214) · Anxiety Disorders (169) · Stress Disorders, Post-Traumatic (80) · Depressive Disorder, Major (67) · Chronic Pain (57) · Obsessive-Compulsive Disorder (51) · Phobia, Social (47) · Substance-Related Disorders (45) · Generalized Anxiety Disorder (44) · Alcoholism (41) · Psychotic Disorders (39) · Schizophrenia (39) · Obesity (35) · Panic Disorder (34)
VA Office of Research and Development (41) · Massachusetts General Hospital (34) · Karolinska Institutet (31) · Yale University (26) · University of Pennsylvania (25) · University of California, Los Angeles (21) · Stanford University (20) · University of Michigan (19) · University of Washington (19) · The University of Hong Kong (15) · Centre for Addiction and Mental Health (14) · Medical University of South Carolina (14) · University of Pittsburgh (14) · McMaster University (13) · New York State Psychiatric Institute (13)
United States (718) · Canada (109) · Sweden (49) · Norway (42) · United Kingdom (39) · Germany (35) · Spain (31) · China (27) · Netherlands (25) · France (24) · Turkey (Türkiye) (23) · Hong Kong (22) · Pakistan (21) · Denmark (18) · Egypt (18)
Ashley E Mason, PhD (5) · Eric Storch, Ph.D. (5) · Qasir Abbas, PHD (4) · Ryan Van Lieshout, MD, PhD (4) · Allison G Harvey, PhD (3) · Benjamin Bohman (3) · Benjamin Bohman, PhD (3) · David F Tolin, Ph.D. (3) · Dawson Church, PhD (3) · Gerhard Andersson (3) · Gretchen Brenes, PhD (3) · Guillem Feixas, Ph.D. (3)
PMID 41170811, PMID 33884617, PMID 35420700, PMID 37795783, PMID 42383885, PMID 32368793, PMID 40243391, PMID 29747068, PMID 34693989, PMID 12150647, PMID 18855829, PMID 18974308, PMID 24506079, PMID 24565357, PMID 25721183, PMID 28569390, PMID 31549310, PMID 33860531, PMID 34197151, PMID 34232578, PMID 35149627, PMID 37651553, PMID 38743265, PMID 38819882, PMID 39436396, PMID 42574109, PMID 10191796, PMID 10417762, PMID 10422602, PMID 10493090, PMID 10510989, PMID 10581887, PMID 10740940, PMID 10748642, PMID 10791509, PMID 10812284, PMID 10885042, PMID 10901493, PMID 10910795, PMID 11127718, PMID 11176814, PMID 11236847, PMID 11260806, PMID 11315822, PMID 11516593, PMID 11556941, PMID 11765093, PMID 11828224, PMID 11952185, PMID 11952187
2023 (3), R01MH060417 (3), 2025 (2), K23DA016574 (2), P20MH071905 (2), P50DA009241 (2), R01AG026364 (2), R01AT008559 (2), R01DA017441 (2), R01DK049587 (2), R01MH053932 (2), R34AT011221 (2), R34AT012767 (2), R34AT013077 (2), R34DA043751 (2)