37 completed, 11 unknown, 3 active not recruiting, 3 not yet recruiting. 57 Phase 1, 27 Phase 2.
Follow Periodontitis: new trials by email Literature Review of Periodontitis trials Research Report on Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Dexamethasone on Short Term Patient Response: IV vs Oral Administration Dexamethasone IV injection, Dexamethasone Capsule, Placebo IV administration - Post Operative Pain, Acute, Periodontitis | Phase 1 / Phase 2 | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 40 | 2026-10-01 | 2026-09-21 |
| Minimally Invasive Non-Surgical Periodontal Therapy Alone vs. Minimally Invasive Non-Surgical Periodontal Therapy With I-PRF With or Without Chlorhexidine on Stage III Periodontitis Patients Minimally Invasive Nonsurgical Therapy, Injectable Platelet-Rich Fibrin, Chlorhexidine 2% - Bony Defects, Periodontal Disease | Phase 1 / Phase 2 | Not yet recruiting | Cairo University | 63 | 2026-09-30 | 2026-08-27 |
| Microbiological Modulation Of The Oral-Gut Axis After Treatment With Or Without Systemic Use Of Probiotics In Patients With Periodontitis: A Randomized Controlled Clinical Study. Probiotics Bifidobacterium animalis subsp. lactis HN019 - Periodontitis Stage IV, Periodontitis | Phase 1 | Completed | University of Sao Paulo | 40 | 2026-06-25 | 2026-08-28 |
| Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication - Intervention Studies, ASA Physical Status I | Phase 1 | Recruiting | Ain Shams University | 60 | 2026-06-01 | 2026-06-12 |
| Injectable Platelet-Rich Fibrin (i-PRF) and Oxygen-Releasing Gel in the Treatment of Stage II Periodontitis. Injectable Platelet-Rich Fibrin (i-PRF, Peroxoborate Oxygen-Releasing Oral Gel, Sterile 0.9% Saline Solution - Stage III Periodontitis | Phase 1 / Phase 2 | Completed | Assiut University | 24 | 2026-01-20 | 2026-11-06 |
| Clinical and Laboratory Evaluation of Resveratrol Loaded Nanoparticles in the Treatment of Periodontitis: A Randomized Controlled Clinical Trial Resveratrol loaded gel - Periodontitis Stage III | Phase 1 | Active not recruiting | Hagar Ahmed Ali Mohammed Elzain | 48 | 2025-08-09 | 2026-02-09 |
| Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique Minimally invasive non-surgical technique (MINST), nano-hyaluronic acid - Periodontal Disease, Periodontitis | Phase 1 / Phase 2 | Active not recruiting | Cairo University | 28 | 2025-07-15 | 2026-05-19 |
| Evaluation of Locally Applied Ferulic Acid as Adjunct to Mechanical Debridement in Treatment of Periodontitis Ferulic Acid, Placebo, mechanical debridement only - Periodontitis | Phase 1 / Phase 2 | Active not recruiting | Salah Awad Alanazi | 80 | 2025-05-16 | 2026-02-13 |
| The Effect of Human Umbilical Cord Mesenchymal Stem Cells and Exosomes on the Healing of Postoperative Pain and Periapical Lesions in the Treatment of Apical Periodontitis: Randomized Controlled Clinical Study Stem Cell Product, Bleeding and clots - Apical Periodontitis | Phase 1 / Phase 2 | Not yet recruiting | TC Erciyes University | 45 | 2025-01-01 | 2025-01-08 |
| Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT Bromelain gel, chlorhexidine gel, SRP - Periodontal Pocket | Phase 1 | Recruiting | Krishnadevaraya College of Dental Sciences & Hospital | 36 | 2024-07-01 | 2025-01-13 |
| Effect of Quercetin in Treatment of Periodontitis Quercetin, scaling and root planing - Inflammation Gum | Phase 1 | Unknown | Assiut University | 20 | 2024-02-20 | 2024-01-31 |
| Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail bromelain-quercetin gel, chlorhexidine gel, SRP - Periodontal Pocket | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 30 | 2024-01-04 | 2025-01-15 |
| Local Delivery of Silk Fibroin and Chlorhexidine silk fibroin, Chlorhexidin, combination of silk fibroin and chlorhexidine - Periodontal Pocket | Phase 1 | Unknown | Krishnadevaraya College of Dental Sciences & Hospital | 15 | 2023-11-01 | 2023-09-22 |
| Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study Diode laser and 3% hydrogen peroxide - Pocket, Periodontal, Periodontal Inflammation | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 10 | 2023-05-28 | 2024-05-08 |
| Clinical Efficacy of Local Delivery of Minocycline and Hyaluronan Gel to Treat Periodontitis in Diabetic Patients Non -surgical treatment and oral hygiene instruction, Application of minocycline and hyaluronic acid gel., local application of placebo gel - Periodontitis and Diabetes, Periodontitis | Phase 1 | Completed | Kafrelsheikh University | 20 | 2023-05-20 | 2025-05-30 |
| Effects of the Adjunctive Use of Hyaluronic Acid-based Gel in the Surgical Periodontal Treatment of Periodontitis open flap debridement and Hyaluronic Acid-Based Gel application, open flap debridement - Periodontitis (Stage 3) | Phase 1 / Phase 2 | Completed | Ordu University | 18 | 2023-04-04 | 2025-02-24 |
| Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy C-PRF - Periodontal Pocket | Phase 1 | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 48 | 2023-02-01 | 2023-09-15 |
| Encapsulated Acellular System From Mesenchymal Stem Cells for Dental Pulp Regeneration Acellular system - Periapical Periodontitis | Phase 1 | Unknown | Universidad de los Andes, Chile | 10 | 2022-12-30 | 2022-10-31 |
| Clinical and Biochemical Assessment of Ozonated Olive Oil Mixed Bone Substitute in Treating Intra Bony Periodontal Defect ozonized olive oil, xenograft bone substitute - Periodontitis | Phase 1 / Phase 2 | Unknown | Ain Shams University | 30 | 2022-07-01 | 2022-12-19 |
| Perio. Maint. With Diode LBR Epic Diode, HP, Sham - Chronic Periodontitis | Phase 1 | Completed | Biolase Inc | 14 | 2022-04-01 | 2023-05-03 |
Showing 20 of 57. Sign in to see all of them.
Chronic Periodontitis (14) · Periodontal Pocket (7) · Periapical Periodontitis (4) · Periodontal Diseases (4) · Aggressive Periodontitis (3) · Gingivitis (3) · Inflammation (3) · Periodontal Attachment Loss (2) · Alveolar Bone Loss (1) · Bone Diseases, Metabolic (1) · Dental Plaque (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Gingival Recession (1)
Mouth Diseases (57) · Stomatognathic Diseases (57) · Periodontal Diseases (53) · Pathologic Processes (17) · Pathological Conditions, Signs and Symptoms (17) · Chronic Disease (14) · Disease Attributes (14) · Jaw Diseases (5) · Periapical Diseases (5) · Gingival Diseases (4) · Infections (4) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Periodontal Atrophy (3)
Tooth Exfoliation (9) · Root Planing (5) · Saline Solution (3) · Control Groups (2) · Amoxicillin (1) · Ashwagandha (1) · Atorvastatin (1) · Calcium (1) · Calcium Hydroxide (1) · Cannabidiol (1) · Cell- and Tissue-Based Therapy (1) · Chlorhexidine (1) · Ciprofloxacin (1) · Debridement (1) · Dental Devices, Home Care (1)
Krishnadevaraya College of Dental Sciences & Hospital (5) · Cairo University (3) · Tatyasaheb Kore Dental College (3) · Ain Shams University (2) · Air Force Military Medical University, China (2) · Assiut University (2) · Misr University for Science and Technology (2) · Tanta University (2) · Alexandria University (1) · Aristotle University Of Thessaloniki (1) · Biolase Inc (1) · Biomedical Development Corporation (1) · Bulent Ecevit University (1) · Ege University (1) · Geistlich Pharma AG (1)
Egypt (13) · India (8) · United States (6) · China (4) · Turkey (Türkiye) (3) · Brazil (2) · Belarus (1) · Chile (1) · Czechia (1) · Greece (1) · Iran (1) · Iraq (1) · Japan (1) · Morocco (1) · Sweden (1)
Dilip Khambete, MDS (2) · Ahmed Mortada Fikry, professor (1) · Ahmed Y Gamal, PhD (1) · Angela Paliaologou-Gallis, DDS (1) · Antonis Konstantinidis, Professor (1) · Baoyong Yan, Doctor (1) · Boyu Liu, Bachelor (1) · David L Steed, MD (1) · Donald Clem, DDS (1) · Eralp Buduneli, Proffessor (1) · Fan Zhang, Bachelor (1) · Guangshun Liu, Master (1) · Hacer Sahin Aydinyurt, Assist Prof (1) · Igor Volotovski, Prof (1)
PMID 20950166, PMID 21555774, PMID 26895633, PMID 27660886, PMID 32047601, PMID 32383274, PMID 32436173, PMID 33899259, PMID 3425152, PMID 3793432, PMID 38847929, PMID 39364843, PMID 41269357, PMID 8910821