15664 completed, 3180 unknown, 1866 recruiting, 1160 terminated. 10816 Not applicable, 2353 Phase 2, 2303 Phase 3, 2185 Phase 4, 2089 Phase 1.
Follow Glucose Metabolism Disorders: new trials by email Literature Review of Glucose Metabolism Disorders trials Research Report on Glucose Metabolism Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance | Phase 2 | Withdrawn | University of Arizona | 2030-04-15 | 2025-07-30 | |
| MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients MEDBRIDGE-Guided NCM/CHW Post-Discharge Support Intervention - Type 2 Diabetes, Medication Adherence | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 45 | 2029-05-01 | 2026-05-20 |
| Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes Insul-In This Together - Diabetes Type 1 | Not applicable | Not yet recruiting | Stanford University | 200 | 2028-01-01 | 2026-10-05 |
| The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction Caloric Restriction, Hyperglycemic clamp - Type2diabetes | Phase 2 | Not yet recruiting | Adrian Vella | 20 | 2027-12-15 | 2026-10-28 |
| Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus Semaglutide (Wegovy) weekly injection - Gestational Diabetes Mellitus (GDM), Metabolic Syndrome | Phase 2 / Phase 3 | Not yet recruiting | University of Massachusetts, Worcester | 226 | 2027-09-01 | 2026-09-28 |
| GLP-1 RA for Stage 1 Type 1 Diabetes Semaglutide, Placebo - Stage 1 Diabetes Mellitus, Type 1 | Phase 2 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 15 | 2027-09-01 | 2026-02-24 |
| South Asians With Type 2 Diabetes at Risk for Depression CHW-led T2D Intervention - Type 2 Diabetes | Not applicable | Not yet recruiting | NYU Langone Health | 100 | 2027-08-01 | 2026-05-19 |
| cfMSC Therapy for Diabetes cfMSC therapy for diabetes - Type II Diabetes Mellitus | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-08-27 |
| Na-Phenylbutyrate VAscular Trial Sodium Phenylbutyrate, Placebo - Diabetes | Early Phase 1 | Not yet recruiting | University of Pennsylvania | 30 | 2027-06-01 | 2026-07-28 |
| A Randomized Trial to Reduce Blood Pressure at One Year Postpartum After Preeclampsia The intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs). - Adverse Pregnancy Outcomes, Cardiovascular Diseases | Not applicable | Not yet recruiting | Maternal-Infantil Vall d´Hebron Hospital | 150 | 2027-06-01 | 2026-10-23 |
| The Prevalence of Hyperglycemia in Surgical Patients With Pre-diabetes Prediabetes or Diabetes, Surgery Complications | Not yet recruiting | University of Calgary | 750 | 2027-05-01 | 2026-06-23 | |
| Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation HEARTS implementation strategies, Supply chain strengthening - Hypertension (HTN), Type 2 Diabetes | Not applicable | Not yet recruiting | University of Michigan | 1440 | 2027-05-01 | 2026-04-17 |
| Trial of CGM Technology in Persons Living With Prediabetes Stelo CGM - Prediabetes | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 100 | 2027-04-01 | 2026-10-23 |
| Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D) ESG with OverStitch - Type 2 Diabetes Mellitus (T2D), Obesity (BMI>30) | Not applicable | Not yet recruiting | Boston Scientific Corporation | 50 | 2027-04-01 | 2026-10-23 |
| Mindful Eating and Mindful Movement for Persons With Type 2 Diabetes Mellitus Standard of Care Diet and Exercise Group, Mindful Eating and Mindful Movement (MEMO) Group - Type 2 Diabetes | Not applicable | Not yet recruiting | Northeastern University | 60 | 2027-03-01 | 2026-09-18 |
| Assessing Trauma-related Links Between Affective and Metabolic Systems prazosin - Posttraumatic Stress Disorder, Metabolic Syndrome | Phase 4 | Not yet recruiting | VA Office of Research and Development | 70 | 2027-03-01 | 2026-10-15 |
| Glucose, Understanding, Integrated Digital Health, and Engagement (GUIDE) Study Integrated Digital Health (IDH) platform, Provider engagement - Diabetes, Diabetes Type 2 | Not applicable | Not yet recruiting | Yale University | 300 | 2027-03-01 | 2026-09-29 |
| Testing a Diabetes Care Program in Rural and Low-Income Clinics Community Health Worker-led diabetes program - Type 2 Diabetes Mellitus | Not applicable | Not yet recruiting | The University of Texas Medical Branch, Galveston | 200 | 2027-03-01 | 2026-08-14 |
| Continuous Glucose Monitoring for In-hospital Management of Type 2 Diabetes Continuous glucose monitoring - Diabetes, Continuous Glucose Monitoring System | Not applicable | Not yet recruiting | Steno Diabetes Center Copenhagen | 314 | 2027-03-01 | 2026-09-01 |
| Tracking Income Dynamics and Everyday Health Study Preventative health review invitation early in SNAP cycle, Financial counseling invitation early in the SNAP cycle, Aim 3 follow-up call early in the SNAP period - HIV, Hypertension | Not applicable | Not yet recruiting | University of Pennsylvania | 400 | 2027-03-01 | 2026-10-19 |
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Diabetes Mellitus, Type 2 (10005) · Diabetes Mellitus (8216) · Diabetes Mellitus, Type 1 (3567) · Insulin Resistance (2958) · Obesity (2767) · Metabolic Syndrome (2093) · Hypertension (1268) · Prediabetic State (912) · Cardiovascular Diseases (909) · Motor Activity (868) · Diabetes, Gestational (829) · Glucose Intolerance (786) · Overweight (770) · Hyperglycemia (766) · Hypoglycemia (662)
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Novo Nordisk A/S (850) · AstraZeneca (386) · Eli Lilly and Company (315) · Sanofi (273) · Merck Sharp & Dohme LLC (194) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (166) · GlaxoSmithKline (150) · University of Aarhus (147) · University of Colorado, Denver (145) · Boehringer Ingelheim (139) · Takeda (123) · Mayo Clinic (119) · Brigham and Women's Hospital (116) · Yale University (111) · Massachusetts General Hospital (110)
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